Category	Term	Count	%	PValue	Genes	List Total	Pop Hits	Pop Total	Fold Enrichment	Bonferroni	Benjamini	FDR
SP_PIR_KEYWORDS	acetylation	322	40.0	2.079143532872512E-80	XRCC5, S100A4, SYT1, PDLIM5, PITPNB, MORF4, SYNCRIP, CCT2, WTAP, HMGN4, RAB1A, PRIM1, NONO, SFRS7, DDX18, H2AFV, AGPS, LOC100129652, HRSP12, LSM4, PELI2, OGT, MRPL39, EIF2B3, STAG2, GTPBP4, BRAF, ROCK1, RAN, PTBP1, RAP1GDS1, VTI1B, SFRS1, DCTN4, SFRS3, SFRS2, MAPK1, SPAG9, RFC3, NNT, RFC4, RFC1, RFC2, EIF2S1, SERBP1, DLD, RAB14, FLII, YME1L1, SRP72, MCTS1, RAD23B, CDV3, UBA6, ACP1, ARFGEF1, NUP50, C11ORF58, PRPF40A, FH, ZC3H14, GPD2, SUB1, MAP2K4, S100A10, WDR70, DLAT, DDX5, VDAC3, PTPN12, PPA1, GART, CCT5, WDR61, NOLC1, PKP4, PCNA, H3F3B, MAP7, GOSR2, C15ORF44, ABCF2, COPS3, CANX, YBX1, MTHFD1, ACTR3, ZNF148, MYC, AP3B1, ABCE1, C1ORF144, EXOSC9, RBBP4, AIFM1, EXOSC2, HN1, ERLIN1, DARS2, GTF2H1, HNRPDL, ATP6V1C1, MED6, WDR48, BLMH, ADK, NUP205, NCK1, RRM1, RAB5A, MTAP, TOMM22, YWHAZ, FKBP1A, ABI1, HPRT1, PDAP1, LOC440434, SUMO3, SUMO2, NUMA1, ACSL1, SET, DDX19B, DHX15, PCMT1, C12ORF5, AGK, BUB3, FEN1, C21ORF59, NMD3, CSNK1A1, GDI2, C1ORF163, PDS5A, MAT2A, ILF3, ACLY, YWHAE, SOD2, ATRX, BLVRA, PAPOLA, PPP1R2, YWHAH, PSMD12, PYGL, PSMD11, PSMD10, RAB22A, YWHAQ, PGK1, PSAT1, PAICS, ATP6V0A2, CALM1, NCBP1, PRPF4B, IDE, EIF5A, CBX3, PNN, FNTA, EIF1, RBM12, API5, SNRPA1, MAGOH, HBXIP, HNRNPU, TIMM8A, PSMA2, SCCPDH, PSMA1, ZNF195, TRIM33, PSMA5, VAMP7, PSMA3, PRPS1, SMARCA4, CAV1, CNBP, ME2, GLUD2, GLUD1, SNX2, ANAPC10, ARPC4, STIP1, TRRAP, ZMYND8, HNRNPM, TUBB, PTK2, DDX3X, CSE1L, ARPC2, HNRNPF, NPM1, HNRNPD, DNAJA1, RPL3, TAF9, HNRNPC, RUNX1, STK38L, TMEM30A, EIF3M, TFDP1, MRPS28, CSTF2, SMCHD1, C21ORF33, AK2, LIN7C, SNW1, SMEK1, MOBKL1B, TSN, IDH3A, PPIF, EIF4B, CORO1C, PSMC6, HNRNPH2, EIF4E, PSMC3, PSMC2, GLS, PRKAR1A, SPTBN1, WDR1, HSPD1, SPCS2, DNAJB1, HNRNPH1, PDCD5, HSP90AB1, UQCRC2, ACOX1, METAP2, SKIV2L2, DEK, PRDX3, DSTN, FUBP1, ACOT9, GSR, MAX, RANBP9, CTTN, MCM7, PRMT5, NARS2, SNTB1, DLG3, MAGOHB, RANBP1, RANBP2, TPR, TBL1XR1, SSBP1, CDC5L, UBE2H, MRPS7, MCM4, CDK2, UBE2N, SMU1, LARP4, RRAS2, UCHL5, UBC, PSME3, KPNA4, MAPRE1, KPNA2, MATR3, UGP2, GLRX3, NUP98, PRKDC, WBP11, TPM4, C3ORF63, RPA1, MTHFS, ANXA7, SAFB, NUDT21, ETNK1, PAFAH1B1, HSPA4, SFRS2IP, MYOF, GAPDH, GTF3C4, GEMIN4, HSPA8, MOBKL3, TNPO3, ENO1, GLRX, ACTB, MSH6, EBP, TCP1, PDCD10, DNM1L, MSH2, PNO1, NF1, GYG1, SMC3, XPNPEP1, ANXA3, ANXA2, DR1, NGDN, CUL4B, CRK	802	2635	19235	2.9308465080183788	1.0728380629622163E-77	1.0728380629622163E-77	3.0073110817395163E-77
SP_PIR_KEYWORDS	phosphoprotein	492	61.118012422360245	2.1525564283030157E-43	XRCC5, SYNCRIP, WTAP, SSR1, MAP3K7, LOC100129652, OGT, TLK2, STAG2, SYK, BRAF, ROCK1, PTBP1, BCL2L13, PROX1, MAPK1, SPAG9, SCYL2, MED17, EIF2S1, MAPK9, FLII, PPP2R5E, SIP1, MCTS1, RAD23B, GNAI3, ARFGEF1, ACP1, BZW1L1, GORASP2, RCHY1, SEC23IP, CDC42EP3, PRPF40A, FH, ZC3H14, GPD2, MAP2K4, ATR, WDR70, VDAC3, GART, HSPA12A, UPF3B, NOLC1, AIDA, PARP8, PKP4, H3F3B, MAP7, LDLR, SLC20A1, NUAK1, PDIA6, YBX1, MTHFD1, CCNE2, ZNF148, KIAA1033, ANP32A, MYC, SRPK2, CDC6, RAP2C, EXOSC9, LYN, AIFM1, EXOSC2, MRPL9, HN1, ELMO2, GTF2H1, WDR48, PJA1, TAF12, NUP205, NCK1, NAB1, C19ORF2, MGEA5, THOC2, TMCO1, PARVA, DEGS1, MFSD6, CREM, POLA1, ABI2, ABI1, MTMR2, GPHN, NUMA1, ACSL1, DDX19B, DHX15, EXOC5, PPP3CA, USP34, BUB3, ETFA, C21ORF59, NMD3, NBPF14, MAT2A, LRRC42, SWAP70, ELAVL1, ACLY, ANKHD1, ATRX, RPS6KA3, LRP8, ZBTB1, NCBP1, MPZL1, PRPF4B, RAB9A, ATP6AP2, XPO4, HBS1L, EIF5, TCEAL1, RGL1, BATF, FNTB, FNTA, PGRMC1, FBXO28, SLC2A1, PSIP1, EIF1, ASPH, API5, NET1, SNRPA1, SPTLC2, SLC33A1, HBXIP, HNRNPU, VAMP7, DNTTIP2, VAMP3, SMARCA4, EID1, GLUD1, MAPKAPK5, PHKA1, CTPS2, STIP1, CCNG2, HNRNPM, PTK2, TUBB, NIPBL, DDX3X, HNRNPF, PRKRA, RPL3, HNRNPD, DNAJA1, TAF9, HNRNPC, SH3TC2, TMEM30A, TFDP1, DNAJA2, SMCHD1, MET, BRIP1, SMEK1, MOBKL1B, DOCK4, CDKN1C, HNRNPH2, GPR39, PRKAR1A, HSPD1, HNRNPH1, HDAC9, DNAJB6, ACOX1, DEK, SKAP2, MAX, WARS, PEX1, EDC3, SNTB1, DLG3, MAGOHB, PDE8A, KIF2A, DLG1, NFX1, SEC23A, TBL1XR1, SSBP1, CDC5L, GAL, CDK2, ATP6V1A, RRAS2, CLDN1, UBC, MAPRE1, NUP98, ABLIM3, WBP11, NFYA, SEC63, APLP2, ORC2L, CHD1L, PAFAH1B1, HSPA4, GTF3C4, HSPA8, MOBKL3, GTF3C3, CEP192, CREB1, PNO1, NF1, GRSF1, GYG1, DRG2, SMC3, SLBP, ANXA2, ORC3L, CUL4B, SYT1, RAB3GAP2, CHMP5, IL6ST, PDLIM5, PITPNB, CDC16, TPD52, HMGN4, RAB1A, NONO, SFRS7, AGPS, CD46, HRSP12, C1ORF107, PELI2, GLE1, FOXO3B, RAPGEF2, GTPBP4, RAN, STRN3, VTI1B, SFRS1, SFRS3, TANK, SFRS2, DCLRE1A, RFC3, RFC1, NAV2, MTF2, UBR5, SERBP1, RAB14, SRP72, GIGYF2, FUS, ERMP1, CDV3, PTPLAD1, TAF9B, AKAP12, ASAP1, CALU, NUP50, AMD1, C11ORF58, GAD1, SUB1, S100A10, DDX5, CDC27, PTPN12, CD55, NSMCE4A, CD59, UTP14A, PLAU, COPS2, ABCF2, COPS3, COPS8, CANX, MTFR1, ACTR3, CTAGE4, AP3B1, C1ORF144, RBBP4, RAB4A, HERC4, GTF2B, SENP2, HNRPDL, SENP3, MED7, PSEN1, POGK, ADK, TOP3A, RAB5A, MTAP, MOSPD2, TOMM22, BID, YWHAZ, GULP1, PPFIA1, FKBP1A, PDAP1, STAU1, SUMO1, SET, KLC1, LANCL2, PRKAA1, C12ORF5, CD24, TPRKB, CSNK1A1, GDI2, PDS5A, ILF3, POLR3C, STAT1, PRPF18, YWHAE, STAT3, CAPRIN1, BLVRA, TJP1, PAPOLA, PPP1R2, YWHAH, ILF2, YAF2, FYN, PYGL, PSMD11, SVIL, YWHAQ, ABCC1, APBB2, PGK1, PAICS, ATP6V0A2, UBXN4, CALM1, BCAR3, TOB1, CEP76, F2RL1, EIF5A, CBX3, CASK, CBX1, FOXO3, PNN, SLC16A1, RC3H2, IFRD1, RBM12, USP1, TOR1AIP1, PRKAB1, TIMM8A, PSMA2, PSMA1, MAP4K5, TRIM33, PSMA5, RIOK3, LYST, PSMA3, CLIP1, RIPK2, AKAP1, DST, RAD17, CAV2, CAV1, SLC38A2, DERL1, MCL1, TH1L, ITGB4, SNX2, TRRAP, ZMYND8, NPM1, SSX2IP, RUNX1, STK38L, EWSR1, RNF14, EIF3M, CREBL2, CSTF2, TSR1, RYK, ZMYM6, ATAD2, SNW1, CORO1C, EIF4B, MSL3, PSMC6, EIF4E, PSMC3, PPID, SPTBN1, YIPF5, WDR1, PDCD5, PLEKHA2, HSP90AB1, UQCRC2, KIAA0802, NAMPT, METAP2, SGPP1, PRKAG2, PDCD4, DSTN, FUBP1, GSR, RANBP9, CTTN, MCM7, CAMSAP1, PSMD4, RANBP1, RANBP2, TPR, FTSJ1, IFNGR1, OSGEPL1, PROSC, MCM4, C20ORF30, LARP4, PSME3, KPNA4, KPNA2, KPNA1, MATR3, PRKDC, TCF7L2, TPM4, C3ORF63, RPA1, MTHFS, CDYL, CEP57, SAFB, NUDT21, SLC25A46, SFRS2IP, GAPDH, MYOF, GEMIN4, TNPO3, ENO1, ACTB, DCTD, MSH6, TCP1, DNM1L, MSH3, MSH2, RGS19, NUP155, RPAP3, TMEM48, DR1, TDP1, NGDN, CRK, BMPR1A	802	7263	19235	1.624676433657698	1.110719117004356E-40	5.55359558502178E-41	3.1134968310541476E-40
GOTERM_CC_FAT	GO:0070013~intracellular organelle lumen	180	22.36024844720497	2.2287387976359322E-23	S100A4, XRCC5, NCBP1, MRPL42, MORF4, IDE, SNRPD1, SYNCRIP, CCT2, CBX1, CDC16, MED21, WTAP, PNN, PRIM1, PGRMC1, MRPL39, OGT, CUL1, GTPBP4, RAN, USP1, STRN3, MAGOH, HKDC1, PTBP1, SKP1, SFRS1, SFRS2, RFC5, MAPK1, RFC3, RFC4, RFC1, NAV2, RFC2, MED17, DLD, FLII, SIP1, RAD17, PNMA1, FUS, RAD23B, ME2, MRPS15, MCL1, GLUD2, GLUD1, HOXA11, TAF9B, TH1L, ANAPC10, TRRAP, CALU, HNRNPM, DDX3X, HNRNPF, NUP50, NPM1, RPL3, TAF9, FH, TFDP1, PRPF40A, NKRF, CSTF2, MRPS28, TSR1, SUB1, RTCD1, ZMYM6, SNW1, DLAT, ATR, DDX5, CDC27, IDH3A, PPIF, CDKN1C, CCT5, HNRNPH2, NOLC1, GLS, PCNA, SPTBN1, DNAJB1, HSPD1, UTP14A, HNRNPH1, HDAC9, PARP2, ENY2, COPS2, PRKAG2, DNAJC10, PDIA6, SKIV2L2, ZNF207, CCNE2, FUBP1, MCCC2, MCM7, ZNF148, NARS2, TPR, MYC, CDC6, TBL1XR1, SRPK2, RBBP4, EXOSC9, SSBP1, AIFM1, EXOSC2, MRPL9, DARS2, CDC5L, MCM4, GTF2B, CDK2, GTF2H1, MED6, SENP3, MED7, TAF12, UBC, TOP3A, C19ORF2, ORC5L, KPNA2, MATR3, KPNA1, NUP98, POLR2K, CREM, POLA1, PRKDC, NFYB, WBP11, NFYA, DIMT1L, TCF7L2, POT1, RPA1, NUMA1, MRPL13, ORC2L, NPAS2, SUMO1, SET, SAFB, NUDT21, MRPL18, PCSK5, GTF3C4, BUB3, GEMIN4, PHLDA1, GTF3C3, NMD3, ETFA, ACTB, POLR3K, CREB1, PDK3, PNO1, ILF3, STAT1, POLR3C, PRPF18, SMC3, STAT3, SOD2, PAPOLA, RPS6KA3, ORC3L, ILF2, CALM1, RCN2	624	1779	12782	2.0725775068102217	1.1455717419848692E-20	1.1455717419848692E-20	3.221936435747892E-20
GOTERM_CC_FAT	GO:0031974~membrane-enclosed lumen	184	22.857142857142858	6.238273591923241E-23	S100A4, XRCC5, NCBP1, MRPL42, MORF4, IDE, SNRPD1, SYNCRIP, CCT2, CBX1, CDC16, MED21, WTAP, PNN, PRIM1, PGRMC1, MRPL39, OGT, CUL1, GTPBP4, RAN, USP1, STRN3, MAGOH, HKDC1, PTBP1, SKP1, SFRS1, SFRS2, TIMM8A, RFC5, MAPK1, RFC3, RFC4, RFC1, NAV2, RFC2, MED17, DLD, FLII, SIP1, RAD17, PNMA1, FUS, RAD23B, ME2, MRPS15, MCL1, GLUD2, GLUD1, HOXA11, TAF9B, TH1L, ANAPC10, TRRAP, CALU, HNRNPM, DDX3X, HNRNPF, NUP50, NPM1, RPL3, TAF9, FH, TFDP1, PRPF40A, NKRF, CSTF2, MRPS28, TSR1, SUB1, RTCD1, ZMYM6, AK2, SNW1, DLAT, ATR, DDX5, CDC27, IDH3A, PPIF, CDKN1C, CCT5, HNRNPH2, NOLC1, GLS, PCNA, SPTBN1, DNAJB1, HSPD1, UTP14A, HNRNPH1, HDAC9, PARP2, ENY2, COPS2, PRKAG2, DNAJC10, PDIA6, SKIV2L2, ZNF207, CCNE2, FUBP1, MCCC2, MCM7, ZNF148, NARS2, TPR, MYC, CDC6, TBL1XR1, SRPK2, RBBP4, EXOSC9, LYN, SSBP1, AIFM1, EXOSC2, MRPL9, DARS2, CDC5L, TIMM23, MCM4, GTF2B, CDK2, GTF2H1, MED6, SENP3, MED7, TAF12, UBC, TOP3A, C19ORF2, ORC5L, KPNA2, MATR3, KPNA1, NUP98, POLR2K, CREM, POLA1, PRKDC, NFYB, WBP11, NFYA, DIMT1L, TCF7L2, POT1, RPA1, NUMA1, MRPL13, ORC2L, NPAS2, SUMO1, SET, SAFB, NUDT21, MRPL18, PCSK5, GTF3C4, BUB3, GEMIN4, PHLDA1, GTF3C3, NMD3, ETFA, ACTB, POLR3K, CREB1, PDK3, PNO1, ILF3, STAT1, POLR3C, PRPF18, SMC3, STAT3, SOD2, PAPOLA, RPS6KA3, ORC3L, ILF2, CALM1, RCN2	624	1856	12782	2.0307388373121134	3.206472626248546E-20	1.603236313124273E-20	9.018248797616445E-20
GOTERM_CC_FAT	GO:0043233~organelle lumen	180	22.36024844720497	3.0090700781041955E-22	S100A4, XRCC5, NCBP1, MRPL42, MORF4, IDE, SNRPD1, SYNCRIP, CCT2, CBX1, CDC16, MED21, WTAP, PNN, PRIM1, PGRMC1, MRPL39, OGT, CUL1, GTPBP4, RAN, USP1, STRN3, MAGOH, HKDC1, PTBP1, SKP1, SFRS1, SFRS2, RFC5, MAPK1, RFC3, RFC4, RFC1, NAV2, RFC2, MED17, DLD, FLII, SIP1, RAD17, PNMA1, FUS, RAD23B, ME2, MRPS15, MCL1, GLUD2, GLUD1, HOXA11, TAF9B, TH1L, ANAPC10, TRRAP, CALU, HNRNPM, DDX3X, HNRNPF, NUP50, NPM1, RPL3, TAF9, FH, TFDP1, PRPF40A, NKRF, CSTF2, MRPS28, TSR1, SUB1, RTCD1, ZMYM6, SNW1, DLAT, ATR, DDX5, CDC27, IDH3A, PPIF, CDKN1C, CCT5, HNRNPH2, NOLC1, GLS, PCNA, SPTBN1, DNAJB1, HSPD1, UTP14A, HNRNPH1, HDAC9, PARP2, ENY2, COPS2, PRKAG2, DNAJC10, PDIA6, SKIV2L2, ZNF207, CCNE2, FUBP1, MCCC2, MCM7, ZNF148, NARS2, TPR, MYC, CDC6, TBL1XR1, SRPK2, RBBP4, EXOSC9, SSBP1, AIFM1, EXOSC2, MRPL9, DARS2, CDC5L, MCM4, GTF2B, CDK2, GTF2H1, MED6, SENP3, MED7, TAF12, UBC, TOP3A, C19ORF2, ORC5L, KPNA2, MATR3, KPNA1, NUP98, POLR2K, CREM, POLA1, PRKDC, NFYB, WBP11, NFYA, DIMT1L, TCF7L2, POT1, RPA1, NUMA1, MRPL13, ORC2L, NPAS2, SUMO1, SET, SAFB, NUDT21, MRPL18, PCSK5, GTF3C4, BUB3, GEMIN4, PHLDA1, GTF3C3, NMD3, ETFA, ACTB, POLR3K, CREB1, PDK3, PNO1, ILF3, STAT1, POLR3C, PRPF18, SMC3, STAT3, SOD2, PAPOLA, RPS6KA3, ORC3L, ILF2, CALM1, RCN2	624	1820	12782	2.025887573964497	1.5466620201455563E-19	5.155540067151855E-20	4.350008414017101E-19
GOTERM_CC_FAT	GO:0031981~nuclear lumen	149	18.509316770186334	1.3228761608102775E-19	S100A4, XRCC5, NCBP1, MORF4, SNRPD1, SYNCRIP, CCT2, CBX1, CDC16, WTAP, MED21, PNN, PRIM1, PGRMC1, OGT, CUL1, GTPBP4, RAN, USP1, STRN3, HKDC1, MAGOH, PTBP1, SKP1, SFRS1, SFRS2, RFC5, MAPK1, RFC3, RFC4, RFC1, NAV2, RFC2, MED17, FLII, SIP1, RAD17, PNMA1, FUS, RAD23B, MCL1, HOXA11, TH1L, TAF9B, ANAPC10, TRRAP, HNRNPM, DDX3X, HNRNPF, NUP50, NPM1, RPL3, TAF9, TFDP1, PRPF40A, NKRF, CSTF2, TSR1, SUB1, RTCD1, ZMYM6, SNW1, ATR, DDX5, CDC27, CDKN1C, CCT5, HNRNPH2, NOLC1, PCNA, SPTBN1, DNAJB1, UTP14A, HNRNPH1, HDAC9, PARP2, ENY2, COPS2, PRKAG2, SKIV2L2, ZNF207, CCNE2, FUBP1, MCM7, ZNF148, TPR, MYC, TBL1XR1, CDC6, SRPK2, RBBP4, EXOSC9, EXOSC2, CDC5L, MCM4, GTF2B, CDK2, GTF2H1, MED6, MED7, SENP3, TAF12, UBC, TOP3A, C19ORF2, ORC5L, KPNA2, MATR3, KPNA1, NUP98, POLR2K, CREM, POLA1, PRKDC, WBP11, NFYB, NFYA, DIMT1L, TCF7L2, POT1, RPA1, NUMA1, ORC2L, NPAS2, SUMO1, SET, SAFB, NUDT21, GTF3C4, BUB3, GEMIN4, PHLDA1, GTF3C3, NMD3, ACTB, POLR3K, CREB1, PNO1, ILF3, STAT1, PRPF18, POLR3C, SMC3, STAT3, PAPOLA, RPS6KA3, ORC3L, ILF2, CALM1	624	1450	12782	2.104904951370469	6.799583466564826E-17	1.6998958666412066E-17	1.9123922942508766E-16
SP_PIR_KEYWORDS	cytoplasm	240	29.81366459627329	1.951373454722337E-19	RAB3GAP2, CHMP5, PITPNB, SYNCRIP, CCT2, CDC16, LOC100129652, HRSP12, C7ORF49, NGFRAP1, GLE1, OGT, FOXO3B, ROCK1, BRAF, RAN, STRN3, RINT1, SFRS1, DCTN4, TANK, SPAG9, SCYL2, SERBP1, FLII, PPP2R5E, SRP72, SIP1, MCTS1, RAD23B, CDV3, RBP1, AKAP12, ASAP1, ACP1, ARIH1, RCHY1, CDC42EP3, FH, GDE1, PAIP1, LGALS8, PTPN12, PPA1, CCT5, UPF3B, C1ORF116, NOLC1, ARF3, MAP7, COPS2, COPS3, COPS8, YBX1, ACTR3, MTHFD1, BAG1, ANP32A, CDC6, ABCE1, SRPK2, EXOSC9, LYN, RAB4A, EXOSC2, HERC4, ELMO2, MTRR, SENP2, WDR48, HNRPDL, BLMH, PRUNE, CHMP1B, NCK1, RRM1, MGEA5, MTAP, PARVA, BID, YWHAZ, ATG12, GULP1, PPFIA1, ABI2, FKBP1A, ABI1, HPRT1, STAU1, NXT2, MTMR2, SUMO3, LOC440434, SUMO2, GPHN, SUMO1, SET, LANCL2, DDX19B, PCMT1, EXOC5, TPRKB, BCAS4, PHLDA1, NMD3, NBPF14, CSNK1A1, GDI2, SWAP70, ELAVL1, ACLY, ILF3, ANKHD1, STAT1, CAPN2, YWHAE, STAT3, CAPRIN1, BLVRA, PAPOLA, ILF2, PTP4A1, SVIL, PTP4A2, YWHAQ, PGK1, CALM1, NCBP1, CNOT8, CEP76, XPO4, IDE, SLC7A8, EIF5A, CASK, FOXO3, RBM9, ATG5, RC3H2, API5, NET1, NUDT4, MAGOH, HBXIP, HNRNPU, ARPC1A, LOC645139, PSMA2, PSMA1, MAP4K5, PSMA5, LYST, PSMA3, RIPK2, CLIP1, DST, CAV2, EID1, CNBP, MCL1, MAPKAPK5, ARPC4, STIP1, ARPC5, CCNG2, PEG10, DDX3X, CSE1L, ARPC2, PRKRA, HNRNPD, RPL3, STK38L, EWSR1, RNF14, EIF3M, TSN, SMEK1, PSMC6, HNRNPH2, PSMC3, PSMC2, PPID, SPTBN1, HSPD1, DNAJB1, WDR1, PDCD6, DNAJB6, PLEKHA2, HSP90AB1, NAMPT, RHOQ, SKAP2, PDCD4, GSR, WARS, CTTN, RANBP9, PEX1, PRMT5, EDC3, SNTB1, KIF2A, MBNL2, CDC5L, SMU1, UBC, PSME3, MAPRE1, KPNA4, KPNA2, UGP2, KPNA1, GLRX3, ABLIM3, WBP11, TPM4, TUBGCP4, MTHFS, CEP57, SH3GLB1, ETNK1, PAFAH1B1, HSPA4, GAPDH, HSPA8, GEMIN4, MOBKL3, ENO1, GLRX, TNPO3, ACTB, TCP1, DNM1L, CEP192, GRSF1, DRG2, XPNPEP1, SLBP, TDP1, NGDN, CRK	802	3332	19235	1.7275239272766463	1.0069087026367259E-16	3.3563623421224195E-17	2.8225021131134396E-16
GOTERM_CC_FAT	GO:0005829~cytosol	137	17.018633540372672	5.110376087541563E-18	NCBP1, CEP76, CHMP5, PDLIM5, IDE, EIF5, SNRPD1, EIF5A, CASK, CCT2, CDC16, FOXO3, MAP3K7, FNTA, LOC100129652, PSIP1, PIK3CA, NGFRAP1, PELI2, OGT, FOXO3B, CUL1, NET1, ROCK1, RAN, SKP1, HBXIP, PSMA2, PSMA1, MAPK1, PSMA5, EIF2S1, PSMA3, RAB14, RIPK2, SIP1, PRPS1, CAV2, CNBP, CAV1, ANAPC10, BCL2L1, PTK2, TUBB, NPM1, HNRNPD, RPL3, AMD1, GGH, CDC27, PTPN12, C21ORF96, PPA1, EIF4B, RPE, CCT5, HNRNPH2, EIF4E, PRKAR1A, SPTBN1, RHEB, HSPD1, WDR1, NAMPT, ENOX2, PRKAG2, PRDX3, PDCD4, CCNE2, GSR, PEX1, BAG1, PSMD4, RANBP2, PSMD6, FOSL1, DLG1, SEC23A, CDC6, LYN, RAB4A, HERC4, MRPS7, CDK2, MTRR, ATP6V1A, CHMP1B, ADK, RRM1, UBC, C19ORF2, MAPRE1, UGP2, KPNA1, BID, ABI2, FKBP1A, ABI1, HPRT1, TCF7L2, LOC440434, TUBGCP4, ANXA7, MTHFS, NUMA1, SET, ACSL1, CEP57, KLC1, LANCL2, SOS2, PAFAH1B1, PPP3CA, TPRKB, HSPA8, BUB3, GEMIN4, ENO1, C21ORF59, GLRX, ACTB, CSNK1A1, DCTD, TCP1, DNM1L, CEP192, RGS19, ACLY, GYG1, YWHAE, CAPRIN1, XPNPEP1, PSMD12, PSMD11, FYN, PSMD10, CRK, CALM1	624	1330	12782	2.110003373819163	2.6267333089963632E-15	5.253466617992727E-16	7.387723915557085E-15
GOTERM_CC_FAT	GO:0005654~nucleoplasm	105	13.043478260869565	5.599273291263083E-18	XRCC5, NCBP1, MORF4, SNRPD1, SYNCRIP, CBX1, CDC16, WTAP, MED21, PNN, PRIM1, OGT, CUL1, RAN, MAGOH, STRN3, USP1, PTBP1, SKP1, SFRS1, SFRS2, RFC5, MAPK1, RFC3, RFC4, RFC1, RFC2, MED17, SIP1, RAD23B, MCL1, HOXA11, TAF9B, TH1L, ANAPC10, TRRAP, DDX3X, HNRNPF, NPM1, NUP50, TAF9, PRPF40A, TFDP1, SUB1, RTCD1, ATR, CDC27, HNRNPH2, PCNA, HNRNPH1, HDAC9, PARP2, ENY2, PRKAG2, CCNE2, MCM7, TPR, MYC, TBL1XR1, CDC6, RBBP4, CDC5L, GTF2B, MCM4, CDK2, GTF2H1, MED6, MED7, SENP3, TAF12, UBC, C19ORF2, TOP3A, ORC5L, KPNA2, KPNA1, NUP98, POLR2K, CREM, POLA1, PRKDC, WBP11, NFYB, NFYA, TCF7L2, POT1, RPA1, SUMO1, NPAS2, ORC2L, NUMA1, SET, NUDT21, GTF3C4, GEMIN4, NMD3, GTF3C3, ACTB, POLR3K, CREB1, PRPF18, POLR3C, RPS6KA3, ORC3L, CALM1	624	882	12782	2.438568376068376	2.8780264717092247E-15	4.796710786182042E-16	8.094489426022677E-15
SP_PIR_KEYWORDS	nucleus	280	34.78260869565217	3.512156103740182E-17	XRCC5, MORF4, SYNCRIP, MED21, WTAP, HMGN4, NONO, SFRS7, H2AFV, HRSP12, C1ORF107, LSM4, NGFRAP1, GLE1, TLK2, OGT, FOXO3B, STAG2, GTPBP4, RAN, PTBP1, BCL2L13, SFRS1, PROX1, SFRS3, SFRS2, RFC5, RAD1, RFC3, DCLRE1A, RFC4, RFC1, RFC2, MTF2, NAV2, MED17, UBR5, SERBP1, FLII, SIP1, PNMA1, FUS, RAD23B, HOXA11, TAF9B, BCL2L1, PIR, NUP50, RCHY1, ARNTL2, PLAGL2, PRPF40A, NKRF, ZC3H14, SUB1, RTCD1, TFCP2, ATR, DDX5, CDC27, UPF3B, NOLC1, PCNA, H3F3B, UTP14A, PARP2, ENY2, COPS2, COPS3, COPS8, YBX1, CCNE2, BAG1, ZNF148, ANP32A, MYC, SRPK2, CDC6, EXOSC9, RBBP4, LYN, AIFM1, EXOSC2, HN1, GTF2B, ZBTB25, GTF2H1, SENP2, MED6, WDR48, HNRPDL, SENP3, MED7, TAF12, PRUNE, POGK, NCK1, NUP205, NAB1, C19ORF2, MGEA5, THOC2, POLR2K, CREM, POLA1, ABI1, DIMT1L, POT1, NXT2, SUMO3, LOC440434, SUMO2, SUMO1, NUMA1, SET, LANCL2, DDX19B, DHX15, PPP3CA, TPRKB, FEN1, BUB3, PHLDA1, NMD3, CAPN7, POLR3K, PDS5A, SWAP70, ILF3, POLR3C, STAT1, PRPF18, STAT3, ATRX, PAPOLA, ILF2, YAF2, ZBTB1, UBXN4, NCBP1, PRPF4B, CNOT8, XPO4, SNRPD1, EIF5A, CBX3, CASK, CBX1, FOXO3, RBM9, TCEAL1, PNN, BATF, GABPB1, PSIP1, RBM12, API5, NET1, SNRPA1, USP1, MAGOH, TOR1AIP1, HNRNPU, PSMA2, HHEX, PSMA1, ZNF195, TRIM33, PSMA5, PSMA3, DNTTIP2, RAD17, SMARCA4, CAV2, EID1, MCL1, MAPKAPK5, TH1L, STIP1, TRRAP, HNRNPM, PEG10, NIPBL, DDX3X, CSE1L, HNRNPF, NPM1, HNRNPD, TAF9, SSX2IP, HNRNPC, RUNX1, EWSR1, RNF14, TFDP1, CREBL2, CSTF2, TSR1, ZMYM6, BRIP1, ATAD2, SNW1, SMEK1, TSN, MSL3, CDKN1C, PSMC6, HNRNPH2, PSMC3, PSMC2, DNAJB1, HDAC9, HNRNPH1, PDCD6, DNAJB6, PLEKHA2, ZNF84, SKIV2L2, DEK, PDCD4, ZNF207, FUBP1, MAX, RANBP9, MCM7, PRMT5, MAGOHB, RANBP2, TPR, FOSL1, NFX1, TBL1XR1, MBNL2, CDC5L, MBNL1, MCM4, SMU1, UBC, ORC5L, PSME3, KPNA4, KPNA2, MATR3, KPNA1, NUP98, PRKDC, NFYB, WBP11, NFYA, TCF7L2, RPA4, APLP2, MSX2, RPA1, ORC2L, NPAS2, CHD1L, CDYL, CEP57, SAFB, NUDT21, PAFAH1B1, SFRS2IP, MYOF, GAPDH, GTF3C4, GEMIN4, TNPO3, GTF3C3, ENO1, MSH6, MSH2, CREB1, PNO1, NUP155, SMC3, SLBP, ORC3L, TMEM48, TDP1, DR1, NGDN	802	4283	19235	1.56793400575144	1.812272549529934E-14	4.530681373824835E-15	5.080046569456624E-14
GOTERM_MF_FAT	GO:0000166~nucleotide binding	195	24.22360248447205	3.7666230453887976E-17	FASTKD3, XRCC5, SYNCRIP, CCT2, RAB1A, NONO, MAP3K7, SFRS7, DDX18, AGPS, PIK3CA, MRPL39, TLK2, SYK, GTPBP4, ROCK1, BRAF, RAN, HKDC1, PTBP1, SFRS1, SFRS3, SFRS2, RFC5, MAPK1, RFC3, NNT, RFC4, RFC1, NAV2, RFC2, SCYL2, DLD, RAB14, MAPK9, YME1L1, FUS, GNAI3, UBA6, ARF6, RTCD1, MAP2K4, ATR, DDX5, VDAC3, GART, CCT5, HSPA12A, UPF3B, NOLC1, ARF3, ARF4, RHEB, ENOX2, ABCF2, NUAK1, ACTR3, MTHFD1, MCCC2, RAP2B, CDC6, ABCE1, SRPK2, RAP2C, LYN, AIFM1, RAB4A, DARS2, MTRR, HNRPDL, SQLE, ADK, RRM1, TOP3A, RAB5A, STEAP1, ALDH18A1, POLA1, GALK2, GPHN, ACSL1, DDX19B, LANCL2, DHX15, PRKAA1, AGK, ETFA, CSNK1A1, MAT2A, SWAP70, PDK3, ELAVL1, ACLY, ATRX, RPS6KA3, PAPOLA, ILF2, FYN, PYGL, RAB22A, ABCC1, PGK1, PAICS, PRPF4B, RAB9A, IDE, EIF5, HBS1L, CASK, RBM9, RALB, RBM12, HNRNPU, MAP4K5, RIOK3, RIPK2, RAD17, PRPS1, SMARCA4, ME2, GLUD2, MAPKAPK5, GLUD1, ARFRP1, CTPS2, HNRNPM, TUBB, PTK2, UBE2D3, DDX3X, HNRNPF, HNRNPD, SRR, TAF9, HNRNPC, RUNX1, STK38L, EWSR1, CSTF2, SMCHD1, RYK, MET, ATAD2, BRIP1, AK2, IDH3A, EIF4B, PSMC6, HNRNPH2, PSMC3, PSMC2, PRKAR1A, NDUFV2, HSPD1, HNRNPH1, HSP90AB1, ACOX1, PRKAG2, RHOQ, SKIV2L2, GSR, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, UBE2A, UBE2H, MCM4, CDK2, UBE2N, ATP6V1A, RRAS2, ORC5L, MATR3, PRKDC, MTHFS, CHD1L, SAFB, ETNK1, HSPA4, GAPDH, HSPA8, ACTB, MSH6, TCP1, DNM1L, MSH3, MSH2, GRSF1, DRG2, SMC3, DUS4L, BMPR1A	641	2245	12983	1.7592813289368991	3.461526578712305E-14	3.461526578712305E-14	5.887068009870725E-14
SP_PIR_KEYWORDS	nucleotide-binding	141	17.51552795031056	8.480582368453125E-16	XRCC5, PRPF4B, RAB9A, IDE, EIF5, HBS1L, CASK, CCT2, RAB1A, MAP3K7, DDX18, RALB, PIK3CA, TLK2, SYK, GTPBP4, BRAF, ROCK1, RAN, HKDC1, HNRNPU, RFC5, MAPK1, RFC3, MAP4K5, RFC4, RFC1, RIOK3, NAV2, RFC2, RAB14, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GNAI3, GLUD1, MAPKAPK5, ARFRP1, UBA6, ARF6, CTPS2, PTK2, UBE2D3, TUBB, DDX3X, TAF9, STK38L, RYK, RTCD1, MAP2K4, MET, AK2, ATAD2, BRIP1, ATR, DDX5, VDAC3, GART, PSMC6, CCT5, HSPA12A, NOLC1, PSMC3, PSMC2, ARF3, PRKAR1A, ARF4, RHEB, HSPD1, HSP90AB1, ABCF2, NUAK1, RHOQ, SKIV2L2, ACTR3, MTHFD1, MCCC2, WARS, MCM7, PEX1, NARS2, KIF2A, RAP2B, CDC6, ABCE1, SRPK2, UBE2A, RAP2C, LYN, RAB4A, UBE2H, DARS2, MCM4, CDK2, UBE2N, ATP6V1A, ADK, RRAS2, RRM1, TOP3A, RAB5A, ORC5L, ALDH18A1, PRKDC, GALK2, MTHFS, GPHN, CHD1L, ACSL1, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ACTB, CSNK1A1, MSH6, TCP1, DNM1L, MSH3, MAT2A, MSH2, PDK3, ACLY, DRG2, SMC3, ATRX, PAPOLA, RPS6KA3, PYGL, FYN, RAB22A, ABCC1, PGK1, PAICS, BMPR1A	802	1686	19235	2.0057618409492286	4.583000645652646E-13	9.170442183403793E-14	1.2878587085651816E-12
UP_SEQ_FEATURE	mutagenesis site	158	19.627329192546583	1.9457076872088504E-14	XRCC5, NCBP1, MPZL1, IL6ST, MORF4, IDE, EIF5A, CBX1, FOXO3, TCEAL1, PNN, FNTB, MAP3K7, GABPB1, FNTA, ATG5, CD46, PSIP1, RALB, TLK2, FOXO3B, ROCK1, RAN, USP1, MAGOH, SFRS1, HBXIP, TANK, RAD1, NPC1, DCLRE1A, MAP4K5, TRIM33, UBR5, FLII, RIPK2, MCTS1, RAD17, SMARCA4, PRPS1, CAV2, EID1, ME2, MCL1, GLUD1, MAPKAPK5, UBA6, ARF6, ARPC4, BCL2L1, ACP1, ARIH1, PEG10, PTK2, DDX3X, GORASP2, HNRNPF, PRKRA, NPM1, DNAJA1, HNRNPC, RCHY1, AMD1, RUNX1, STK38L, EIF3M, RNF14, SUB1, GGH, ATAD2, BRIP1, TFCP2, ATR, UPF3B, EIF4E, PSMC3, GPR39, CD59, PCNA, RHEB, EMR2, PDCD6, PLAU, NAMPT, ENOX2, SLC20A1, LDLR, NUAK1, RHOQ, PEX3, YBX1, CCNE2, MTHFD1, MAX, PRMT5, RANBP2, PDE8A, NFX1, DLG1, LYN, AIFM1, RAB4A, CDC5L, GTF2B, CDK2, UBE2N, HNRPDL, SENP3, PRUNE, CHMP1B, PSEN1, UBC, CLDN1, RAB5A, UCHL5, PSME3, MAPRE1, UGP2, YWHAZ, GULP1, PRKDC, WBP11, TCF7L2, MTMR2, MSX2, SUMO3, MTHFS, SUMO2, SUMO1, CHD1L, SH3GLB1, LANCL2, DDX19B, NUDT21, C12ORF5, MYOF, FEN1, ENO1, NMD3, MSH6, TMPRSS2, EBP, KLK7, DNM1L, SWAP70, MSH2, RGS19, ANKHD1, STAT1, CAPRIN1, XPNPEP1, SLBP, SOD2, ANXA2, TDP1, PTP4A1, PTP4A2, ABCC1, CRK, PAICS	802	2045	19113	1.8412733447554708	4.1733283495659634E-11	4.1733283495659634E-11	3.368416656712725E-11
SP_PIR_KEYWORDS	atp-binding	113	14.037267080745341	3.6105318906389055E-13	XRCC5, PRPF4B, IDE, CASK, CCT2, MAP3K7, DDX18, PIK3CA, TLK2, SYK, BRAF, ROCK1, HKDC1, HNRNPU, RFC5, MAPK1, MAP4K5, RFC3, RFC4, RFC1, NAV2, RFC2, RIOK3, RIPK2, MAPK9, YME1L1, RAD17, SMARCA4, PRPS1, MAPKAPK5, GLUD1, UBA6, CTPS2, PTK2, UBE2D3, DDX3X, TAF9, STK38L, RYK, RTCD1, MET, MAP2K4, ATAD2, BRIP1, AK2, ATR, DDX5, GART, CCT5, HSPA12A, PSMC6, NOLC1, PSMC3, PSMC2, HSPD1, HSP90AB1, ABCF2, NUAK1, SKIV2L2, MTHFD1, ACTR3, MCCC2, WARS, MCM7, PEX1, NARS2, KIF2A, ABCE1, CDC6, SRPK2, UBE2A, LYN, UBE2H, DARS2, MCM4, CDK2, UBE2N, ATP6V1A, ADK, RRM1, TOP3A, ORC5L, ALDH18A1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ACTB, CSNK1A1, MSH6, TCP1, MSH3, MAT2A, MSH2, PDK3, ACLY, SMC3, ATRX, PAPOLA, RPS6KA3, FYN, ABCC1, PGK1, PAICS, BMPR1A	802	1326	19235	2.0438675182330748	1.8629897624578007E-10	3.104982937429668E-11	5.222267063231811E-10
SP_PIR_KEYWORDS	mrna splicing	36	4.472049689440994	1.806723564473864E-12	NCBP1, PRPF4B, SNRPD1, SYNCRIP, SKIV2L2, WBP11, RBM9, WTAP, YBX1, PNN, NONO, HNRNPM, SFRS7, HNRNPF, DHX15, LSM4, MAGOHB, SFRS2IP, HNRNPC, GEMIN4, PRPF40A, SRPK2, SNRPA1, MAGOH, PTBP1, SNW1, CDC5L, SFRS1, DDX5, PRPF18, SFRS3, HNRNPU, SFRS2, HNRNPH1, THOC2, SIP1	802	209	19235	4.1311792289610905	9.322969063418896E-10	1.331852406138978E-10	2.613353977665156E-9
SP_PIR_KEYWORDS	mrna processing	40	4.968944099378882	3.4849224560631477E-12	NCBP1, PRPF4B, SNRPD1, SYNCRIP, SKIV2L2, WBP11, RBM9, WTAP, YBX1, PNN, NONO, HNRNPM, SFRS7, HNRNPF, NUDT21, DHX15, MAGOHB, LSM4, SFRS2IP, HNRNPC, GEMIN4, PRPF40A, SRPK2, SNRPA1, CSTF2, MAGOH, PTBP1, SNW1, CDC5L, SFRS1, DDX5, PRPF18, SFRS3, HNRNPU, SLBP, SFRS2, PAPOLA, HNRNPH1, THOC2, SIP1	802	260	19235	3.6898139267216576	1.7981975908298864E-9	2.2477464334258457E-10	5.040590167482151E-9
GOTERM_MF_FAT	GO:0017076~purine nucleotide binding	160	19.875776397515526	4.6107134807496014E-12	FASTKD3, XRCC5, PRPF4B, RAB9A, HBS1L, IDE, EIF5, CASK, CCT2, RAB1A, MAP3K7, DDX18, AGPS, RALB, PIK3CA, TLK2, SYK, GTPBP4, ROCK1, BRAF, RAN, HKDC1, HNRNPU, RFC5, MAPK1, RFC3, MAP4K5, RFC4, RFC1, RIOK3, SCYL2, NAV2, RFC2, DLD, RAB14, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GNAI3, GLUD2, GLUD1, MAPKAPK5, ARFRP1, UBA6, CTPS2, ARF6, TUBB, PTK2, UBE2D3, DDX3X, SRR, TAF9, RUNX1, STK38L, SMCHD1, RYK, RTCD1, MAP2K4, MET, AK2, ATAD2, BRIP1, ATR, DDX5, GART, PSMC6, CCT5, HSPA12A, NOLC1, PSMC3, PSMC2, ARF3, PRKAR1A, ARF4, RHEB, HSPD1, HSP90AB1, ACOX1, ABCF2, NUAK1, PRKAG2, RHOQ, SKIV2L2, ACTR3, MTHFD1, MCCC2, GSR, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, RAP2B, CDC6, ABCE1, SRPK2, UBE2A, RAP2C, LYN, AIFM1, RAB4A, UBE2H, DARS2, MCM4, CDK2, MTRR, UBE2N, ATP6V1A, SQLE, ADK, RRAS2, RRM1, TOP3A, RAB5A, ORC5L, STEAP1, ALDH18A1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, LANCL2, DDX19B, DHX15, ETNK1, PRKAA1, HSPA4, AGK, HSPA8, ETFA, ACTB, CSNK1A1, MSH6, TCP1, DNM1L, MSH3, MAT2A, SWAP70, MSH2, PDK3, ACLY, DRG2, SMC3, ATRX, PAPOLA, RPS6KA3, ILF2, PYGL, FYN, RAB22A, ABCC1, DUS4L, PGK1, PAICS, BMPR1A	641	1918	12983	1.689617532563659	4.237284967345545E-9	2.1186424836727724E-9	7.206413243920906E-9
GOTERM_BP_FAT	GO:0008380~RNA splicing	46	5.714285714285714	6.1158981855883064E-12	FUS, NCBP1, PRPF4B, POLR2K, SNRPD1, SYNCRIP, SKIV2L2, WBP11, RBM9, WTAP, YBX1, PNN, NONO, HNRNPM, SFRS7, HNRNPF, PRMT5, NUDT21, DHX15, HNRNPD, MAGOHB, LSM4, HNRNPC, SFRS2IP, GEMIN4, PRPF40A, SRPK2, SNRPA1, CSTF2, MAGOH, PTBP1, SNW1, MBNL1, CDC5L, SFRS1, DDX5, PRPF18, SFRS3, HNRNPU, SFRS2, PAPOLA, UPF3B, HNRNPH2, THOC2, HNRNPH1, SIP1	683	284	13528	3.2081331326170788	1.76504456605997E-8	1.76504456605997E-8	1.0965195418322082E-8
GOTERM_BP_FAT	GO:0032268~regulation of cellular protein metabolic process	62	7.7018633540372665	1.1094033417831724E-11	HSP90AB1, NCBP1, IL6ST, IDE, PRKAG2, EIF5, EIF5A, CDC16, PDCD4, FNTA, ATG5, HRSP12, PSMD4, EIF1, PSMD6, EIF2B3, CUL1, SYK, GTPBP4, LYN, MAGOH, SKP1, UBE2N, LOC645139, PSMA2, MAPK1, PSMA1, MAP4K5, PSEN1, PSMA5, EIF2S1, NCK1, PSMA3, UBC, MGEA5, PSME3, GATC, CAV1, PTPLAD1, FKBP1A, ANAPC10, SET, TAF9, CD24, BUB3, BMP4, PAIP1, ANKHD1, CDC27, YWHAE, SELT, EIF4B, PSMC6, EIF4E, PSMD12, PSMC3, PSMD11, PSMC2, PSMD10, PRKAR1A, NGDN, BMP7, BMPR1A	683	474	13528	2.590754366131055	3.20173255685674E-8	1.6008662950817154E-8	1.989050035788864E-8
GOTERM_MF_FAT	GO:0030554~adenyl nucleotide binding	137	17.018633540372672	1.7033985807152332E-11	XRCC5, FASTKD3, PRPF4B, IDE, CASK, CCT2, RAB1A, MAP3K7, DDX18, AGPS, PIK3CA, TLK2, SYK, BRAF, ROCK1, HKDC1, HNRNPU, RFC5, MAPK1, RFC3, MAP4K5, RFC4, RFC1, NAV2, RFC2, SCYL2, RIOK3, DLD, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GLUD2, GLUD1, MAPKAPK5, UBA6, CTPS2, PTK2, UBE2D3, DDX3X, SRR, TAF9, RUNX1, STK38L, SMCHD1, RYK, RTCD1, MET, MAP2K4, AK2, ATAD2, BRIP1, ATR, DDX5, GART, PSMC6, CCT5, HSPA12A, NOLC1, PSMC3, PSMC2, PRKAR1A, HSPD1, HSP90AB1, ACOX1, ABCF2, NUAK1, PRKAG2, SKIV2L2, MTHFD1, ACTR3, GSR, MCCC2, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, CDC6, ABCE1, SRPK2, UBE2A, LYN, AIFM1, UBE2H, DARS2, MCM4, CDK2, MTRR, UBE2N, ATP6V1A, SQLE, ADK, RRM1, TOP3A, ORC5L, STEAP1, ALDH18A1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, LANCL2, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ETFA, ACTB, CSNK1A1, MSH6, TCP1, MSH3, MAT2A, SWAP70, MSH2, PDK3, ACLY, SMC3, ATRX, PAPOLA, RPS6KA3, ILF2, PYGL, FYN, ABCC1, DUS4L, PGK1, PAICS, BMPR1A	641	1577	12983	1.7595673769880409	1.5654283425092785E-8	5.218094512038363E-9	2.6623470095188395E-8
GOTERM_BP_FAT	GO:0006397~mRNA processing	48	5.962732919254658	3.532109088102446E-11	FUS, NCBP1, PRPF4B, POLR2K, SNRPD1, SYNCRIP, SKIV2L2, WBP11, WTAP, RBM9, YBX1, PNN, NONO, HNRNPM, SFRS7, HNRNPF, PRMT5, NUDT21, DHX15, HNRNPD, MAGOHB, LSM4, HNRNPC, SFRS2IP, GEMIN4, PRPF40A, SRPK2, SNRPA1, CSTF2, MAGOH, PTBP1, GRSF1, SNW1, MBNL1, CDC5L, SFRS1, DDX5, PRPF18, SFRS3, HNRNPU, SLBP, SFRS2, PAPOLA, UPF3B, HNRNPH2, THOC2, HNRNPH1, SIP1	683	321	13528	2.9617547652604643	1.0193662991486718E-7	3.3978877822526954E-8	6.332731006253312E-8
SP_PIR_KEYWORDS	rna-binding	59	7.329192546583851	3.77880257783114E-11	SYNCRIP, EIF5A, RBM9, PDCD4, YBX1, NONO, SFRS7, DDX18, LSM4, MAGOHB, RBM12, SNRPA1, EXOSC9, MAGOH, PTBP1, EXOSC2, MBNL2, MBNL1, CDC5L, SFRS1, HNRNPU, SFRS3, SFRS2, HNRPDL, LARP4, EIF2S1, SERBP1, THOC2, AKAP1, MATR3, FUS, DIMT1L, STAU1, HNRNPM, DDX3X, DDX19B, SAFB, HNRNPF, NUDT21, PRKRA, NPM1, HNRNPD, HNRNPC, EWSR1, ZC3H14, CSTF2, PNO1, GRSF1, ELAVL1, ILF3, ANKHD1, DDX5, SLBP, EIF4B, PAPOLA, UPF3B, EIF4E, HNRNPH2, HNRNPH1	802	540	19235	2.6204511868476956	1.949860517491686E-8	2.1665117477809304E-9	5.465724539632788E-8
GOTERM_MF_FAT	GO:0001882~nucleoside binding	138	17.142857142857142	4.0429567394503125E-11	XRCC5, FASTKD3, PRPF4B, IDE, CASK, CCT2, RAB1A, MAP3K7, DDX18, AGPS, PIK3CA, TLK2, SYK, BRAF, ROCK1, HKDC1, HNRNPU, RFC5, MAPK1, RFC3, MAP4K5, RFC4, RFC1, NAV2, RFC2, SCYL2, RIOK3, DLD, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GLUD2, GLUD1, MAPKAPK5, UBA6, CTPS2, PTK2, UBE2D3, DDX3X, SRR, TAF9, RUNX1, STK38L, SMCHD1, RYK, RTCD1, MET, MAP2K4, AK2, ATAD2, BRIP1, ATR, DDX5, GART, PSMC6, CCT5, HSPA12A, NOLC1, PSMC3, PSMC2, PRKAR1A, HSPD1, HSP90AB1, ACOX1, ABCF2, NUAK1, PRKAG2, SKIV2L2, ACTR3, MTHFD1, GSR, MCCC2, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, CDC6, ABCE1, SRPK2, UBE2A, LYN, AIFM1, UBE2H, DARS2, MCM4, CDK2, MTRR, UBE2N, ATP6V1A, SQLE, ADK, RRM1, TOP3A, ORC5L, STEAP1, ALDH18A1, POLA1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, LANCL2, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ETFA, ACTB, CSNK1A1, MSH6, TCP1, MSH3, MAT2A, SWAP70, MSH2, PDK3, ACLY, SMC3, ATRX, PAPOLA, RPS6KA3, ILF2, PYGL, FYN, ABCC1, DUS4L, PGK1, PAICS, BMPR1A	641	1612	12983	1.7339280668000914	3.715475449528327E-8	9.288688707087545E-9	6.318963130524935E-8
GOTERM_MF_FAT	GO:0001883~purine nucleoside binding	137	17.018633540372672	4.995856482969315E-11	XRCC5, FASTKD3, PRPF4B, IDE, CASK, CCT2, RAB1A, MAP3K7, DDX18, AGPS, PIK3CA, TLK2, SYK, BRAF, ROCK1, HKDC1, HNRNPU, RFC5, MAPK1, RFC3, MAP4K5, RFC4, RFC1, NAV2, RFC2, SCYL2, RIOK3, DLD, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GLUD2, GLUD1, MAPKAPK5, UBA6, CTPS2, PTK2, UBE2D3, DDX3X, SRR, TAF9, RUNX1, STK38L, SMCHD1, RYK, RTCD1, MET, MAP2K4, AK2, ATAD2, BRIP1, ATR, DDX5, GART, PSMC6, CCT5, HSPA12A, NOLC1, PSMC3, PSMC2, PRKAR1A, HSPD1, HSP90AB1, ACOX1, ABCF2, NUAK1, PRKAG2, SKIV2L2, MTHFD1, ACTR3, GSR, MCCC2, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, CDC6, ABCE1, SRPK2, UBE2A, LYN, AIFM1, UBE2H, DARS2, MCM4, CDK2, MTRR, UBE2N, ATP6V1A, SQLE, ADK, RRM1, TOP3A, ORC5L, STEAP1, ALDH18A1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, LANCL2, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ETFA, ACTB, CSNK1A1, MSH6, TCP1, MSH3, MAT2A, SWAP70, MSH2, PDK3, ACLY, SMC3, ATRX, PAPOLA, RPS6KA3, ILF2, PYGL, FYN, ABCC1, DUS4L, PGK1, PAICS, BMPR1A	641	1601	12983	1.733190351973854	4.591194580072511E-8	9.182389293371784E-9	7.808310664714213E-8
GOTERM_MF_FAT	GO:0032555~purine ribonucleotide binding	150	18.633540372670808	1.400208123482861E-10	FASTKD3, XRCC5, PRPF4B, RAB9A, IDE, EIF5, HBS1L, CASK, CCT2, RAB1A, MAP3K7, DDX18, RALB, PIK3CA, TLK2, SYK, GTPBP4, ROCK1, BRAF, RAN, HKDC1, HNRNPU, RFC5, MAPK1, RFC3, MAP4K5, RFC4, RFC1, RIOK3, SCYL2, NAV2, RFC2, RAB14, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GNAI3, GLUD2, GLUD1, MAPKAPK5, ARFRP1, UBA6, ARF6, CTPS2, PTK2, UBE2D3, TUBB, DDX3X, SRR, TAF9, RUNX1, STK38L, SMCHD1, RYK, RTCD1, MAP2K4, MET, AK2, ATAD2, BRIP1, ATR, DDX5, GART, PSMC6, CCT5, HSPA12A, NOLC1, PSMC3, PSMC2, ARF3, PRKAR1A, ARF4, RHEB, HSPD1, HSP90AB1, ABCF2, NUAK1, PRKAG2, RHOQ, SKIV2L2, ACTR3, MTHFD1, MCCC2, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, RAP2B, CDC6, ABCE1, SRPK2, UBE2A, RAP2C, LYN, RAB4A, UBE2H, DARS2, MCM4, CDK2, UBE2N, ATP6V1A, ADK, RRAS2, RRM1, TOP3A, RAB5A, ORC5L, ALDH18A1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, LANCL2, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ACTB, CSNK1A1, MSH6, TCP1, DNM1L, MSH3, MAT2A, SWAP70, MSH2, PDK3, ACLY, DRG2, SMC3, ATRX, PAPOLA, RPS6KA3, ILF2, PYGL, FYN, RAB22A, ABCC1, PGK1, PAICS, BMPR1A	641	1836	12983	1.6547622689221293	1.2867908194547084E-7	2.1446514786305215E-8	2.1884637435576337E-7
GOTERM_MF_FAT	GO:0032553~ribonucleotide binding	150	18.633540372670808	1.400208123482861E-10	FASTKD3, XRCC5, PRPF4B, RAB9A, IDE, EIF5, HBS1L, CASK, CCT2, RAB1A, MAP3K7, DDX18, RALB, PIK3CA, TLK2, SYK, GTPBP4, ROCK1, BRAF, RAN, HKDC1, HNRNPU, RFC5, MAPK1, RFC3, MAP4K5, RFC4, RFC1, RIOK3, SCYL2, NAV2, RFC2, RAB14, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GNAI3, GLUD2, GLUD1, MAPKAPK5, ARFRP1, UBA6, ARF6, CTPS2, PTK2, UBE2D3, TUBB, DDX3X, SRR, TAF9, RUNX1, STK38L, SMCHD1, RYK, RTCD1, MAP2K4, MET, AK2, ATAD2, BRIP1, ATR, DDX5, GART, PSMC6, CCT5, HSPA12A, NOLC1, PSMC3, PSMC2, ARF3, PRKAR1A, ARF4, RHEB, HSPD1, HSP90AB1, ABCF2, NUAK1, PRKAG2, RHOQ, SKIV2L2, ACTR3, MTHFD1, MCCC2, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, RAP2B, CDC6, ABCE1, SRPK2, UBE2A, RAP2C, LYN, RAB4A, UBE2H, DARS2, MCM4, CDK2, UBE2N, ATP6V1A, ADK, RRAS2, RRM1, TOP3A, RAB5A, ORC5L, ALDH18A1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, LANCL2, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ACTB, CSNK1A1, MSH6, TCP1, DNM1L, MSH3, MAT2A, SWAP70, MSH2, PDK3, ACLY, DRG2, SMC3, ATRX, PAPOLA, RPS6KA3, ILF2, PYGL, FYN, RAB22A, ABCC1, PGK1, PAICS, BMPR1A	641	1836	12983	1.6547622689221293	1.2867908194547084E-7	2.1446514786305215E-8	2.1884637435576337E-7
SP_PIR_KEYWORDS	protein transport	54	6.70807453416149	1.4300119470994702E-10	RAB9A, CHMP5, TIMM17A, XPO4, EIF5A, RAB1A, PEX1, RANBP2, GLE1, TPR, AP3B1, SEC23A, SCAMP1, RAN, RAB4A, RINT1, VTI1B, TIMM23, TIMM8A, SENP2, CHMP1B, LYST, VAMP7, NUP205, RAB14, RAB5A, TOMM22, KPNA4, KPNA2, KPNA1, NUP98, DERL1, SNX2, ARF6, LMAN1, SEC63, NXT2, TMED2, CSE1L, DDX19B, NUP50, BCAP29, EXOC5, NMD3, TNPO3, LIN7C, NUP155, AP4S1, TMEM48, ARF3, ARF4, RAB22A, GOSR2, YIPF5	802	485	19235	2.670360182019179	7.378859923079517E-8	7.378860189533043E-9	2.0683948998012625E-7
GOTERM_BP_FAT	GO:0016071~mRNA metabolic process	51	6.3354037267080745	1.5627958786729218E-10	NCBP1, PRPF4B, SNRPD1, SYNCRIP, SKIV2L2, WTAP, RBM9, YBX1, PNN, NONO, SFRS7, PRMT5, LSM4, MAGOHB, SNRPA1, SRPK2, MAGOH, PTBP1, MBNL1, CDC5L, SFRS1, SFRS3, HNRNPU, SFRS2, LOC645139, SERBP1, SIP1, THOC2, FUS, POLR2K, WBP11, HNRNPM, HNRNPF, NUDT21, DHX15, HNRNPD, SFRS2IP, HNRNPC, GEMIN4, PRPF40A, CSTF2, PAIP1, GRSF1, ELAVL1, SNW1, PRPF18, DDX5, SLBP, PAPOLA, UPF3B, HNRNPH2, HNRNPH1	683	370	13528	2.730117526017965	4.510226647713722E-7	1.1275568523316792E-7	2.8019423448100156E-7
GOTERM_BP_FAT	GO:0000398~nuclear mRNA splicing, via spliceosome	30	3.7267080745341614	5.276789564618097E-10	FUS, NCBP1, POLR2K, SNRPD1, YBX1, HNRNPM, SFRS7, PRMT5, HNRNPF, NUDT21, HNRNPD, SFRS2IP, HNRNPC, GEMIN4, SRPK2, SNRPA1, CSTF2, MAGOH, PTBP1, SNW1, MBNL1, SFRS1, HNRNPU, SFRS3, SFRS2, PAPOLA, HNRNPH2, UPF3B, HNRNPH1, SIP1	683	153	13528	3.883673527976345	1.5228804682854147E-6	3.045762791975548E-7	9.460778604974962E-7
GOTERM_BP_FAT	GO:0000377~RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	30	3.7267080745341614	5.276789564618097E-10	FUS, NCBP1, POLR2K, SNRPD1, YBX1, HNRNPM, SFRS7, PRMT5, HNRNPF, NUDT21, HNRNPD, SFRS2IP, HNRNPC, GEMIN4, SRPK2, SNRPA1, CSTF2, MAGOH, PTBP1, SNW1, MBNL1, SFRS1, HNRNPU, SFRS3, SFRS2, PAPOLA, HNRNPH2, UPF3B, HNRNPH1, SIP1	683	153	13528	3.883673527976345	1.5228804682854147E-6	3.045762791975548E-7	9.460778604974962E-7
GOTERM_BP_FAT	GO:0000375~RNA splicing, via transesterification reactions	30	3.7267080745341614	5.276789564618097E-10	FUS, NCBP1, POLR2K, SNRPD1, YBX1, HNRNPM, SFRS7, PRMT5, HNRNPF, NUDT21, HNRNPD, SFRS2IP, HNRNPC, GEMIN4, SRPK2, SNRPA1, CSTF2, MAGOH, PTBP1, SNW1, MBNL1, SFRS1, HNRNPU, SFRS3, SFRS2, PAPOLA, HNRNPH2, UPF3B, HNRNPH1, SIP1	683	153	13528	3.883673527976345	1.5228804682854147E-6	3.045762791975548E-7	9.460778604974962E-7
GOTERM_MF_FAT	GO:0032559~adenyl ribonucleotide binding	127	15.77639751552795	5.762020583151906E-10	XRCC5, FASTKD3, PRPF4B, IDE, CASK, CCT2, RAB1A, MAP3K7, DDX18, PIK3CA, TLK2, SYK, BRAF, ROCK1, HKDC1, HNRNPU, RFC5, MAPK1, MAP4K5, RFC3, RFC4, RFC1, NAV2, RFC2, SCYL2, RIOK3, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GLUD2, GLUD1, MAPKAPK5, UBA6, CTPS2, PTK2, UBE2D3, DDX3X, SRR, TAF9, RUNX1, STK38L, SMCHD1, RYK, RTCD1, MET, MAP2K4, ATAD2, BRIP1, AK2, ATR, DDX5, GART, CCT5, HSPA12A, PSMC6, NOLC1, PSMC3, PSMC2, PRKAR1A, HSPD1, HSP90AB1, ABCF2, NUAK1, PRKAG2, SKIV2L2, MTHFD1, ACTR3, MCCC2, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, ABCE1, CDC6, SRPK2, UBE2A, LYN, UBE2H, DARS2, MCM4, CDK2, UBE2N, ATP6V1A, ADK, RRM1, TOP3A, ORC5L, ALDH18A1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, LANCL2, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ACTB, CSNK1A1, MSH6, TCP1, MSH3, MAT2A, SWAP70, MSH2, PDK3, ACLY, SMC3, ATRX, PAPOLA, RPS6KA3, ILF2, PYGL, FYN, ABCC1, PGK1, PAICS, BMPR1A	641	1497	12983	1.7182998341977769	5.295295770757491E-7	7.56470995844083E-8	9.005788004223803E-7
GOTERM_BP_FAT	GO:0031396~regulation of protein ubiquitination	24	2.981366459627329	6.300843898793039E-10	GTPBP4, FKBP1A, ANAPC10, SKP1, CDC16, CDC27, UBE2N, PSMA2, PSMA1, PSMC6, ATG5, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, CUL1, BUB3	683	100	13528	4.753616398243046	1.8184220095252002E-6	3.030705645334919E-7	1.1296809487859605E-6
GOTERM_BP_FAT	GO:0031400~negative regulation of protein modification process	26	3.229813664596273	8.794091060203269E-10	CAV1, ANAPC10, FKBP1A, CDC16, SET, ATG5, PSMD4, PSMD6, BUB3, GTPBP4, YWHAE, CDC27, PSMA2, PSMA1, PSMC6, PSEN1, PSMD12, PSMD11, PSMC3, PSMA5, PSMC2, PSMD10, PSMA3, UBC, MGEA5, PSME3	683	119	13528	4.32752193117364	2.5379714462259173E-6	3.62567743827924E-7	1.5766961736218832E-6
GOTERM_MF_FAT	GO:0005524~ATP binding	125	15.527950310559005	9.698782626449897E-10	XRCC5, FASTKD3, PRPF4B, IDE, CASK, CCT2, RAB1A, MAP3K7, DDX18, PIK3CA, TLK2, SYK, BRAF, ROCK1, HKDC1, HNRNPU, RFC5, MAPK1, MAP4K5, RFC3, RFC4, RFC1, NAV2, RFC2, SCYL2, RIOK3, MAPK9, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, GLUD1, MAPKAPK5, UBA6, CTPS2, PTK2, UBE2D3, DDX3X, SRR, TAF9, RUNX1, STK38L, SMCHD1, RYK, RTCD1, MET, MAP2K4, ATAD2, BRIP1, AK2, ATR, DDX5, GART, CCT5, HSPA12A, PSMC6, NOLC1, PSMC3, PSMC2, HSPD1, HSP90AB1, ABCF2, NUAK1, PRKAG2, SKIV2L2, MTHFD1, ACTR3, MCCC2, WARS, MCM7, PEX1, NARS2, TPR, KIF2A, ABCE1, CDC6, SRPK2, UBE2A, LYN, UBE2H, DARS2, MCM4, CDK2, UBE2N, ATP6V1A, ADK, RRM1, TOP3A, ORC5L, ALDH18A1, PRKDC, GALK2, MTHFS, CHD1L, ACSL1, LANCL2, DDX19B, DHX15, ETNK1, HSPA4, PRKAA1, AGK, HSPA8, ACTB, CSNK1A1, MSH6, TCP1, MSH3, MAT2A, SWAP70, MSH2, PDK3, ACLY, SMC3, ATRX, PAPOLA, RPS6KA3, ILF2, PYGL, FYN, ABCC1, PGK1, PAICS, BMPR1A	641	1477	12983	1.7141410097839256	8.913177506064685E-7	1.1141476230491776E-7	1.5158775790169443E-6
GOTERM_BP_FAT	GO:0051443~positive regulation of ubiquitin-protein ligase activity	20	2.484472049689441	9.79209527072187E-10	ANAPC10, SKP1, CDC16, CDC27, UBE2N, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, CUL1	683	70	13528	5.659067140765531	2.8259946001085723E-6	3.532497617753094E-7	1.7556286979747426E-6
GOTERM_BP_FAT	GO:0051438~regulation of ubiquitin-protein ligase activity	21	2.608695652173913	1.0701544336487666E-9	ANAPC10, SKP1, CDC16, CDC27, UBE2N, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, CUL1, BUB3	683	78	13528	5.3325824980290575	3.0884608582804063E-6	3.4316278862966954E-7	1.9186842226126544E-6
GOTERM_BP_FAT	GO:0015031~protein transport	79	9.813664596273291	1.243319371386664E-9	RAB3GAP2, RAB9A, CHMP5, TIMM17A, XPO4, EIF5A, PEX3, CANX, RAB1A, SSR1, PEX1, GLE1, RANBP2, TPR, AP3B1, SEC23A, SCAMP1, LYN, RAN, RAB4A, RINT1, VTI1B, TIMM23, TIMM8A, SENP2, MAPK1, CHMP1B, PSEN1, NUP205, VAMP7, LYST, MGEA5, RAB5A, RAB14, TOMM22, SRP72, KPNA4, KPNA2, KPNA1, BID, YWHAZ, NUP98, DERL1, AKAP12, SNX2, ARF6, LMAN1, SEC63, NXT2, TMED2, CEP57, CSE1L, DDX19B, NPM1, NUP50, BCAP29, PPP3CA, EXOC5, CD24, PCSK5, SEC23IP, TNPO3, NMD3, GDI2, LIN7C, AP4S1, NUP155, YWHAE, TMEM48, YWHAH, ARF3, RAB22A, ARF4, YWHAQ, PCNA, SPTBN1, GOSR2, YIPF5, TOB1	683	762	13528	2.053454152784343	3.5882131693698582E-6	3.588218963068712E-7	2.2291523182893513E-6
GOTERM_BP_FAT	GO:0006259~DNA metabolic process	60	7.453416149068323	1.2665119840374948E-9	XRCC5, MORF4, PRIM1, NONO, CCNE2, MCM7, PSIP1, MYC, CDC6, UBE2A, RBBP4, SSBP1, AIFM1, RAN, USP1, MCM4, CDK2, GTF2H1, UBE2N, RAD1, RFC5, RFC3, DCLRE1A, RFC4, RFC1, RFC2, RRM1, TOP3A, ORC5L, KPNA2, RAD17, RAD23B, NUP98, POLA1, PRKDC, POT1, RPA4, GIN1, RPA1, SUMO1, ORC2L, SET, CHD1L, FEN1, MSH6, MSH3, SWAP70, MSH2, BRIP1, TSN, ATR, SMC3, SOD2, ATRX, ORC3L, TDP1, PCNA, HSPD1, CUL4B, PARP2	683	506	13528	2.3486247026892517	3.6551469726475716E-6	3.3228664053641666E-7	2.2707345559425107E-6
GOTERM_BP_FAT	GO:0051439~regulation of ubiquitin-protein ligase activity during mitotic cell cycle	20	2.484472049689441	1.274875818124818E-9	ANAPC10, SKP1, CDC16, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, CUL1, BUB3	683	71	13528	5.579361969768833	3.679284999003052E-6	3.0660760030887246E-7	2.2857301607004388E-6
GOTERM_BP_FAT	GO:0046907~intracellular transport	71	8.819875776397515	1.7671949813221508E-9	NCBP1, RAB3GAP2, CHMP5, TIMM17A, EIF5A, PEX3, SSR1, PEX1, ANP32A, RANBP1, RANBP2, GLE1, TPR, AP3B1, SEC23A, SCAMP1, NUDT4, RAN, VTI1B, TIMM23, TIMM8A, MAPK1, HHEX, NPC1, PSEN1, NUP205, VAMP7, LYST, MGEA5, RAB14, TOMM22, SRP72, KPNA4, THOC2, KPNA2, DST, KPNA1, BID, YWHAZ, NUP98, DERL1, AKAP12, SNX2, BCL2L1, LMAN1, SEC63, SET, CEP57, CSE1L, KLC1, DDX19B, NPM1, NUP50, BCAP29, PAFAH1B1, PPP3CA, EXOC5, CD24, SEC23IP, HSPA8, NUP155, AP4S1, YWHAE, PPIF, SLC25A14, YWHAH, YWHAQ, PCNA, SPTBN1, GOSR2, TOB1	683	657	13528	2.140453857656369	5.10011161281021E-6	3.9231720139198956E-7	3.168411022436146E-6
GOTERM_BP_FAT	GO:0045184~establishment of protein localization	79	9.813664596273291	1.9062639117537034E-9	RAB3GAP2, RAB9A, CHMP5, TIMM17A, XPO4, EIF5A, PEX3, CANX, RAB1A, SSR1, PEX1, GLE1, RANBP2, TPR, AP3B1, SEC23A, SCAMP1, LYN, RAN, RAB4A, RINT1, VTI1B, TIMM23, TIMM8A, SENP2, MAPK1, CHMP1B, PSEN1, NUP205, VAMP7, LYST, MGEA5, RAB5A, RAB14, TOMM22, SRP72, KPNA4, KPNA2, KPNA1, BID, YWHAZ, NUP98, DERL1, AKAP12, SNX2, ARF6, LMAN1, SEC63, NXT2, TMED2, CEP57, CSE1L, DDX19B, NPM1, NUP50, BCAP29, PPP3CA, EXOC5, CD24, PCSK5, SEC23IP, TNPO3, NMD3, GDI2, LIN7C, AP4S1, NUP155, YWHAE, TMEM48, YWHAH, ARF3, RAB22A, ARF4, YWHAQ, PCNA, SPTBN1, GOSR2, YIPF5, TOB1	683	769	13528	2.0347621123818844	5.501462558177295E-6	3.9296261500343377E-7	3.4177483621000704E-6
GOTERM_BP_FAT	GO:0051351~positive regulation of ligase activity	20	2.484472049689441	2.128793503168171E-9	ANAPC10, SKP1, CDC16, CDC27, UBE2N, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, CUL1	683	73	13528	5.426502737720372	6.143679102454946E-6	4.0957978109101845E-7	3.816722493610314E-6
GOTERM_MF_FAT	GO:0003723~RNA binding	74	9.192546583850932	2.1435543513965988E-9	NCBP1, SNRPD1, EIF5A, SYNCRIP, RBM9, PDCD4, YBX1, NONO, FUBP1, SFRS7, DDX18, LSM4, MAGOHB, RBM12, SNRPA1, EXOSC9, MAGOH, PTBP1, EXOSC2, MBNL2, MRPS7, CDC5L, MBNL1, SFRS1, HNRNPU, SFRS3, SFRS2, LOC645139, HNRPDL, PSMA1, LARP4, EIF2S1, SERBP1, UBR5, SRP72, THOC2, AKAP1, MCTS1, MATR3, FUS, CNBP, DIMT1L, STAU1, HNRNPM, DDX3X, HNRNPF, DDX19B, SAFB, NPM1, NUDT21, PRKRA, RPL3, HNRNPD, HNRNPC, EWSR1, ZC3H14, NKRF, CSTF2, PAIP1, RTCD1, PNO1, GRSF1, ELAVL1, ILF3, TSN, ANKHD1, DDX5, SLBP, EIF4B, PAPOLA, HNRNPH2, EIF4E, UPF3B, ILF2, HNRNPH1	641	718	12983	2.087489516293744	1.969924494749087E-6	2.1888069101638763E-7	3.350282151703965E-6
GOTERM_BP_FAT	GO:0051340~regulation of ligase activity	21	2.608695652173913	2.1991369324011495E-9	ANAPC10, SKP1, CDC16, CDC27, UBE2N, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, CUL1, BUB3	683	81	13528	5.1350794425465	6.346689201408573E-6	3.966692552204165E-7	3.942841653170603E-6
GOTERM_BP_FAT	GO:0031397~negative regulation of protein ubiquitination	20	2.484472049689441	2.731148299950581E-9	GTPBP4, ANAPC10, CDC16, CDC27, PSMA2, PSMA1, PSMC6, ATG5, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, BUB3	683	74	13528	5.353171619643069	7.882062962649705E-6	4.636524822965171E-7	4.896686900401903E-6
GOTERM_BP_FAT	GO:0010605~negative regulation of macromolecule metabolic process	76	9.440993788819876	2.8832691297485604E-9	HSP90AB1, COPS2, IDE, CBX3, CDC16, RBM9, PDCD4, TCEAL1, FNTA, ATG5, ZNF148, PSMD4, PSMD6, EIF2B3, MYC, NFX1, TBL1XR1, CDC6, GTPBP4, STRN3, PROX1, PSMA2, INHBB, PSMA1, HHEX, PSEN1, TRIM33, PSMA5, PSMA3, NAB1, UBC, MGEA5, PSME3, RAD17, SMARCA4, EID1, CAV1, TAF9B, TH1L, ANAPC10, FKBP1A, BCL2L1, POT1, SUMO1, ORC2L, SET, LANCL2, NPM1, PRKRA, TAF9, BUB3, ENO1, BMP4, NKRF, MSH6, MSH3, MSH2, SNW1, ILF3, ATR, ANKHD1, CDC27, YWHAE, STAT3, CDKN1C, PSMC6, PSMD12, YAF2, PSMC3, PSMD11, DR1, PSMC2, PSMD10, YWHAQ, HDAC9, DNAJB6	683	734	13528	2.0508335959722497	8.321080242068568E-6	4.6228405214954194E-7	5.169425021378515E-6
GOTERM_BP_FAT	GO:0031399~regulation of protein modification process	42	5.217391304347826	3.186746610409361E-9	CAV1, IL6ST, PTPLAD1, PRKAG2, FKBP1A, ANAPC10, CDC16, PDCD4, FNTA, SET, ATG5, PSMD4, CD24, PSMD6, CUL1, BUB3, SYK, BMP4, GTPBP4, LYN, SKP1, CDC27, YWHAE, UBE2N, PSMA2, PSMA1, MAP4K5, PSMC6, PSMD12, PSEN1, PSMA5, PSMD11, PSMC3, PSMD10, PSMC2, PSMA3, PRKAR1A, UBC, MGEA5, PSME3, BMP7, BMPR1A	683	295	13528	2.8199419311611287	9.196908538400272E-6	4.840499265856835E-7	5.713530992768057E-6
GOTERM_BP_FAT	GO:0031401~positive regulation of protein modification process	32	3.9751552795031055	4.1271099920181E-9	CAV1, IL6ST, PRKAG2, FKBP1A, ANAPC10, CDC16, FNTA, PSMD4, CD24, PSMD6, CUL1, SYK, BMP4, LYN, SKP1, CDC27, UBE2N, PSMA2, PSMA1, PSMC6, PSMD12, PSEN1, PSMA5, PSMD11, PSMC3, PSMD10, PSMC2, PSMA3, UBC, PSME3, BMP7, BMPR1A	683	187	13528	3.3893878062339007	1.1910768513589964E-5	5.955417949898845E-7	7.399512180761292E-6
GOTERM_BP_FAT	GO:0051437~positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	19	2.360248447204969	4.2092824130836155E-9	ANAPC10, SKP1, CDC16, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, CUL1	683	68	13528	5.534234777366291	1.214791515047331E-5	5.784754963933381E-7	7.546839375649483E-6
GOTERM_BP_FAT	GO:0031398~positive regulation of protein ubiquitination	21	2.608695652173913	4.35975979134553E-9	FKBP1A, ANAPC10, SKP1, CDC16, CDC27, UBE2N, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, CUL1	683	84	13528	4.951683748169839	1.2582187582932391E-5	5.719210518506657E-7	7.81663090920759E-6
GOTERM_MF_FAT	GO:0003697~single-stranded DNA binding	17	2.111801242236025	4.975171452103684E-9	RAD23B, CNBP, MSH3, SSBP1, MSH2, SUB1, WBP11, MCM4, RPA4, YBX1, POT1, RPA1, HNRPDL, FUBP1, MCM7, TDP1, HSPD1	641	55	12983	6.260416962133031	4.572172164651889E-6	4.57218157223771E-7	7.775976396118267E-6
GOTERM_BP_FAT	GO:0032269~negative regulation of cellular protein metabolic process	31	3.8509316770186333	6.463968277309307E-9	HSP90AB1, CAV1, IDE, FKBP1A, ANAPC10, CDC16, SET, ATG5, TAF9, PSMD4, PSMD6, EIF2B3, BUB3, GTPBP4, ANKHD1, CDC27, YWHAE, PSMA2, PSMA1, PSMC6, PSMD12, PSEN1, PSMA5, PSMD11, PSMC3, PSMD10, PSMC2, PSMA3, UBC, MGEA5, PSME3	683	180	13528	3.4111599154058894	1.8654838424780884E-5	8.110871679845033E-7	1.1589274584444809E-5
SP_PIR_KEYWORDS	mRNA transport	18	2.236024844720497	7.103439995568998E-9	ENY2, NCBP1, NUP98, MAGOH, EIF5A, NUP155, NXT2, SENP2, TMEM48, UPF3B, NUP205, DDX19B, NUP50, MAGOHB, GLE1, RANBP2, THOC2, TPR	802	74	19235	5.833894992249108	3.665368308425343E-6	3.332158559077314E-7	1.0274544448574119E-5
GOTERM_CC_FAT	GO:0043232~intracellular non-membrane-bounded organelle	186	23.1055900621118	7.412877701717264E-9	S100A4, XRCC5, MRPL42, PRPF4B, CEP76, PDLIM5, MORF4, CBX3, CASK, CCT2, CBX1, CDC16, WTAP, HMGN4, MRPS30, PNN, PRIM1, FNTB, FNTA, H2AFV, LOC100129652, PGRMC1, MRPL39, STAG2, GTPBP4, ROCK1, RAN, HKDC1, PTBP1, DCTN4, RFC5, ARPC1A, MAPK1, RFC3, RFC4, RFC1, NAV2, RFC2, LYST, PSMA3, FLII, CLIP1, DST, RAD17, SMARCA4, PNMA1, FUS, MRPS15, AKAP12, ARPC4, ARPC5, HNRNPM, TUBB, PTK2, ARPC2, HNRNPF, NPM1, RPL3, HNRNPD, CDC42EP3, STK38L, NKRF, CSTF2, MRPS28, SMCHD1, TSR1, SUB1, ZMYM6, C21ORF33, SNW1, ATR, SMEK1, DDX5, CDC27, DOCK4, CDKN1C, CORO1C, MSL3, CCT5, HNRNPH2, NOLC1, PCNA, SPTBN1, H3F3B, MAP7, DNAJB1, WDR1, UTP14A, HNRNPH1, PARP2, COPS2, ENOX2, RHOQ, SKIV2L2, DSTN, ZNF207, ACTR3, FUBP1, CTTN, RANBP9, MCM7, BAG1, ZNF148, CAMSAP1, SNTB1, RANBP1, TPR, MYC, IFNGR1, DLG1, KIF2A, CDC6, TBL1XR1, SRPK2, UBE2A, RBBP4, ADAM10, EXOSC9, LYN, SSBP1, EXOSC2, MRPL9, CDC5L, MRPS7, MCM4, CDK2, ELMO2, SENP3, TAF12, PSEN1, UBC, TOP3A, ORC5L, MAPRE1, PARVA, NUP98, YWHAZ, POLA1, ABI2, ABI1, DIMT1L, RPA4, POT1, TPM4, STAU1, TUBGCP4, RPA1, SUMO3, SUMO2, GPHN, NUMA1, MRPL13, ORC2L, CDYL, CEP57, KLC1, LANCL2, SAFB, NUDT21, MRPL19, MRPL18, PAFAH1B1, ZWILCH, MYOF, GEMIN4, BUB3, PHLDA1, NMD3, ACTB, MSH6, TCP1, PDS5A, CEP192, CREB1, PNO1, ILF3, STAT1, SMC3, STAT3, ATRX, PAPOLA, ORC3L, ILF2, PSMD10, SVIL, PTP4A1, CALM1	624	2596	12782	1.4676499348109517	3.810211921861928E-6	5.443168776819718E-7	1.0716293796786402E-5
GOTERM_CC_FAT	GO:0043228~non-membrane-bounded organelle	186	23.1055900621118	7.412877701717264E-9	S100A4, XRCC5, MRPL42, PRPF4B, CEP76, PDLIM5, MORF4, CBX3, CASK, CCT2, CBX1, CDC16, WTAP, HMGN4, MRPS30, PNN, PRIM1, FNTB, FNTA, H2AFV, LOC100129652, PGRMC1, MRPL39, STAG2, GTPBP4, ROCK1, RAN, HKDC1, PTBP1, DCTN4, RFC5, ARPC1A, MAPK1, RFC3, RFC4, RFC1, NAV2, RFC2, LYST, PSMA3, FLII, CLIP1, DST, RAD17, SMARCA4, PNMA1, FUS, MRPS15, AKAP12, ARPC4, ARPC5, HNRNPM, TUBB, PTK2, ARPC2, HNRNPF, NPM1, RPL3, HNRNPD, CDC42EP3, STK38L, NKRF, CSTF2, MRPS28, SMCHD1, TSR1, SUB1, ZMYM6, C21ORF33, SNW1, ATR, SMEK1, DDX5, CDC27, DOCK4, CDKN1C, CORO1C, MSL3, CCT5, HNRNPH2, NOLC1, PCNA, SPTBN1, H3F3B, MAP7, DNAJB1, WDR1, UTP14A, HNRNPH1, PARP2, COPS2, ENOX2, RHOQ, SKIV2L2, DSTN, ZNF207, ACTR3, FUBP1, CTTN, RANBP9, MCM7, BAG1, ZNF148, CAMSAP1, SNTB1, RANBP1, TPR, MYC, IFNGR1, DLG1, KIF2A, CDC6, TBL1XR1, SRPK2, UBE2A, RBBP4, ADAM10, EXOSC9, LYN, SSBP1, EXOSC2, MRPL9, CDC5L, MRPS7, MCM4, CDK2, ELMO2, SENP3, TAF12, PSEN1, UBC, TOP3A, ORC5L, MAPRE1, PARVA, NUP98, YWHAZ, POLA1, ABI2, ABI1, DIMT1L, RPA4, POT1, TPM4, STAU1, TUBGCP4, RPA1, SUMO3, SUMO2, GPHN, NUMA1, MRPL13, ORC2L, CDYL, CEP57, KLC1, LANCL2, SAFB, NUDT21, MRPL19, MRPL18, PAFAH1B1, ZWILCH, MYOF, GEMIN4, BUB3, PHLDA1, NMD3, ACTB, MSH6, TCP1, PDS5A, CEP192, CREB1, PNO1, ILF3, STAT1, SMC3, STAT3, ATRX, PAPOLA, ORC3L, ILF2, PSMD10, SVIL, PTP4A1, CALM1	624	2596	12782	1.4676499348109517	3.810211921861928E-6	5.443168776819718E-7	1.0716293796786402E-5
GOTERM_BP_FAT	GO:0031145~anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	18	2.236024844720497	1.3858842406440893E-8	ANAPC10, CDC16, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, BUB3	683	65	13528	5.484941997972745	3.99958196096728E-5	1.6665244223501574E-6	2.4847572543951202E-5
GOTERM_BP_FAT	GO:0051436~negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	18	2.236024844720497	1.3858842406440893E-8	ANAPC10, CDC16, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, BUB3	683	65	13528	5.484941997972745	3.99958196096728E-5	1.6665244223501574E-6	2.4847572543951202E-5
GOTERM_BP_FAT	GO:0051248~negative regulation of protein metabolic process	31	3.8509316770186333	1.6069461453370773E-8	HSP90AB1, CAV1, IDE, FKBP1A, ANAPC10, CDC16, SET, ATG5, TAF9, PSMD4, PSMD6, EIF2B3, BUB3, GTPBP4, ANKHD1, CDC27, YWHAE, PSMA2, PSMA1, PSMC6, PSMD12, PSEN1, PSMA5, PSMD11, PSMC3, PSMD10, PSMC2, PSMA3, UBC, MGEA5, PSME3	683	187	13528	3.2834694372890914	4.6375390682640294E-5	1.8550569215181056E-6	2.8810999452844044E-5
SP_PIR_KEYWORDS	dna replication	19	2.360248447204969	1.8260190186336175E-8	CDC6, RBBP4, SSBP1, POLA1, MCM4, RPA4, RPA1, RFC5, PRIM1, RFC3, ORC2L, RFC4, MCM7, ORC3L, RFC1, RFC2, RRM1, PCNA, ORC5L	802	88	19235	5.178318408524144	9.42221380773045E-6	7.851878748299512E-7	2.6411868414566442E-5
GOTERM_BP_FAT	GO:0006403~RNA localization	22	2.732919254658385	1.9803052699045676E-8	ENY2, NCBP1, NUP98, RAN, MAGOH, EIF5A, NUP155, STAU1, NXT2, SENP2, HHEX, TMEM48, UPF3B, NUP205, DDX19B, NPM1, NUP50, MAGOHB, GLE1, RANBP2, THOC2, TPR	683	100	13528	4.357481698389458	5.714997768935248E-5	2.1981364614065413E-6	3.550496864290764E-5
GOTERM_BP_FAT	GO:0032270~positive regulation of cellular protein metabolic process	35	4.3478260869565215	2.104818553497131E-8	CAV1, IL6ST, PRKAG2, EIF5A, FKBP1A, ANAPC10, CDC16, FNTA, PSMD4, CD24, PSMD6, CUL1, SYK, BMP4, LYN, SKP1, CDC27, UBE2N, PSMA2, MAPK1, PSMA1, PSMC6, PSMD12, PSEN1, PSMA5, PSMD11, PSMC3, PSMD10, PSMC2, PSMA3, UBC, MGEA5, PSME3, BMP7, BMPR1A	683	233	13528	2.975260621217929	6.0743219128633896E-5	2.2498146570182342E-6	3.773737152767964E-5
GOTERM_BP_FAT	GO:0051352~negative regulation of ligase activity	18	2.236024844720497	2.2753141664941663E-8	ANAPC10, CDC16, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, BUB3	683	67	13528	5.321212386092962	6.566341176883483E-5	2.3451960966536234E-6	4.079419332336798E-5
GOTERM_BP_FAT	GO:0051444~negative regulation of ubiquitin-protein ligase activity	18	2.236024844720497	2.2753141664941663E-8	ANAPC10, CDC16, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, BUB3	683	67	13528	5.321212386092962	6.566341176883483E-5	2.3451960966536234E-6	4.079419332336798E-5
GOTERM_BP_FAT	GO:0010498~proteasomal protein catabolic process	22	2.732919254658385	2.8621743981606098E-8	RAD23B, TBL1XR1, DERL1, ERLIN1, ANAPC10, CDC16, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, BUB3	683	102	13528	4.272040880773979	8.259894281315017E-5	2.848352988027436E-6	5.1316029858750056E-5
GOTERM_BP_FAT	GO:0043161~proteasomal ubiquitin-dependent protein catabolic process	22	2.732919254658385	2.8621743981606098E-8	RAD23B, TBL1XR1, DERL1, ERLIN1, ANAPC10, CDC16, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UBC, PSME3, PSMD4, PSMD6, BUB3	683	102	13528	4.272040880773979	8.259894281315017E-5	2.848352988027436E-6	5.1316029858750056E-5
KEGG_PATHWAY	hsa03430:Mismatch repair	12	1.4906832298136645	4.7247012380818446E-8	RFC5, RPA1, MSH6, RFC3, RFC4, MSH3, RFC1, SSBP1, RFC2, MSH2, PCNA, RPA4	330	23	5085	8.039525691699604	7.465000274486933E-6	7.465000274486933E-6	5.692758443531787E-5
SP_PIR_KEYWORDS	proteasome	15	1.8633540372670807	4.798873801656497E-8	RAD23B, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMC2, PSMD10, PSMA3, UCHL5, PSME3, PSMD4, PSMD6	802	56	19235	6.424229604560029	2.4761882813084668E-5	1.9047819853623693E-6	6.94117624044921E-5
GOTERM_BP_FAT	GO:0050657~nucleic acid transport	21	2.608695652173913	5.9569112577673616E-8	ENY2, NCBP1, NUP98, RAN, MAGOH, EIF5A, NUP155, NXT2, SENP2, HHEX, TMEM48, UPF3B, NUP205, DDX19B, NPM1, NUP50, MAGOHB, GLE1, RANBP2, THOC2, TPR	683	97	13528	4.288056029342954	1.7190168709813047E-4	5.730532376624353E-6	1.0680165259957519E-4
GOTERM_BP_FAT	GO:0051236~establishment of RNA localization	21	2.608695652173913	5.9569112577673616E-8	ENY2, NCBP1, NUP98, RAN, MAGOH, EIF5A, NUP155, NXT2, SENP2, HHEX, TMEM48, UPF3B, NUP205, DDX19B, NPM1, NUP50, MAGOHB, GLE1, RANBP2, THOC2, TPR	683	97	13528	4.288056029342954	1.7190168709813047E-4	5.730532376624353E-6	1.0680165259957519E-4
GOTERM_BP_FAT	GO:0050658~RNA transport	21	2.608695652173913	5.9569112577673616E-8	ENY2, NCBP1, NUP98, RAN, MAGOH, EIF5A, NUP155, NXT2, SENP2, HHEX, TMEM48, UPF3B, NUP205, DDX19B, NPM1, NUP50, MAGOHB, GLE1, RANBP2, THOC2, TPR	683	97	13528	4.288056029342954	1.7190168709813047E-4	5.730532376624353E-6	1.0680165259957519E-4
GOTERM_BP_FAT	GO:0051247~positive regulation of protein metabolic process	35	4.3478260869565215	6.061510577114687E-8	CAV1, IL6ST, PRKAG2, EIF5A, FKBP1A, ANAPC10, CDC16, FNTA, PSMD4, CD24, PSMD6, CUL1, SYK, BMP4, LYN, SKP1, CDC27, UBE2N, PSMA2, MAPK1, PSMA1, PSMC6, PSMD12, PSEN1, PSMA5, PSMD11, PSMC3, PSMD10, PSMC2, PSMA3, UBC, MGEA5, PSME3, BMP7, BMPR1A	683	243	13528	2.8528219125258327	1.7491990043860817E-4	5.643055068560443E-6	1.0867701635275395E-4
GOTERM_BP_FAT	GO:0008104~protein localization	82	10.186335403726709	8.162253051691756E-8	RAB3GAP2, RAB9A, CHMP5, TIMM17A, XPO4, EIF5A, PEX3, CANX, RAB1A, SSR1, PEX1, LOC100129652, GLE1, RANBP2, TPR, AP3B1, SCAMP1, SEC23A, LYN, RAN, RAB4A, RINT1, VTI1B, TIMM23, TIMM8A, SENP2, MAPK1, CHMP1B, PSEN1, NUP205, VAMP7, LYST, MGEA5, RAB5A, RAB14, TOMM22, SRP72, KPNA4, KPNA2, KPNA1, BID, CAV1, YWHAZ, NUP98, DERL1, AKAP12, SNX2, ARF6, LMAN1, SEC63, NXT2, TMED2, CEP57, CSE1L, SH3GLB1, DDX19B, NPM1, NUP50, BCAP29, PPP3CA, EXOC5, CD24, PCSK5, SEC23IP, TNPO3, NMD3, GDI2, LIN7C, AP4S1, NUP155, YWHAE, TMEM48, YWHAH, ARF3, RAB22A, ARF4, PCNA, YWHAQ, SPTBN1, GOSR2, YIPF5, TOB1	683	882	13528	1.8414424823125932	2.3553488997341E-4	7.361305176423194E-6	1.4634126899171207E-4
GOTERM_CC_FAT	GO:0031967~organelle envelope	62	7.7018633540372665	1.0598569637403612E-7	UQCRC2, HCCS, ABCF2, TIMM17A, CBX3, EIF5A, WTAP, ATP5S, RANBP2, GLE1, TPR, LYN, AIFM1, RAN, TMEM70, TIMM23, TIMM8A, SENP2, NPC1, NNT, PSEN1, NUP205, TOMM22, KPNA4, AKAP1, KPNA2, MATR3, KPNA1, BID, NUP98, ALDH18A1, MCL1, POLA1, BCL2L1, ANXA7, SUMO1, ACSL1, CSE1L, SH3GLB1, DDX19B, NUP50, SLC25A46, MRPL19, PAFAH1B1, MYOF, AGK, GPD2, DNM1L, AK2, NUP155, VDAC3, SOD2, PPIF, SLC25A14, TMEM48, FYN, SDHC, NDUFV2, PCNA, BIK, HSPD1, UBXN4	624	620	12782	2.048397435897436	5.447516697487664E-5	6.809558164899698E-6	1.5321621965602716E-4
SP_PIR_KEYWORDS	host-virus interaction	34	4.22360248447205	1.1521005518901811E-7	NUP98, CAV1, DERL1, LDLR, IDE, POLA1, SYNCRIP, DDX3X, CD46, NPM1, PSIP1, HSPA8, DLG1, SYK, NFX1, ABCE1, LYN, RAN, CREB1, STAT1, YWHAE, GTF2B, STAT3, WDR48, MAPK1, EIF4E, FYN, PSMC3, PSMC2, PSMA3, CLDN1, HSPD1, KPNA2, KPNA1	802	285	19235	2.861224132650829	5.944662486778718E-5	4.246304690758151E-6	1.6664179331993267E-4
GOTERM_CC_FAT	GO:0031975~envelope	62	7.7018633540372665	1.2072181520455888E-7	UQCRC2, HCCS, ABCF2, TIMM17A, CBX3, EIF5A, WTAP, ATP5S, RANBP2, GLE1, TPR, LYN, AIFM1, RAN, TMEM70, TIMM23, TIMM8A, SENP2, NPC1, NNT, PSEN1, NUP205, TOMM22, KPNA4, AKAP1, KPNA2, MATR3, KPNA1, BID, NUP98, ALDH18A1, MCL1, POLA1, BCL2L1, ANXA7, SUMO1, ACSL1, CSE1L, SH3GLB1, DDX19B, NUP50, SLC25A46, MRPL19, PAFAH1B1, MYOF, AGK, GPD2, DNM1L, AK2, NUP155, VDAC3, SOD2, PPIF, SLC25A14, TMEM48, FYN, SDHC, NDUFV2, PCNA, BIK, HSPD1, UBXN4	624	622	12782	2.04181094896529	6.204909163942673E-5	6.894533650769752E-6	1.7451919421818118E-4
GOTERM_CC_FAT	GO:0044427~chromosomal part	45	5.590062111801243	1.2529280975069645E-7	XRCC5, NUP98, MORF4, POLA1, CBX3, CBX1, HMGN4, POT1, RPA4, PRIM1, SUMO3, RPA1, SUMO2, ORC2L, MCM7, CDYL, H2AFV, PAFAH1B1, ZWILCH, TPR, STAG2, BUB3, MSH6, TCP1, UBE2A, RBBP4, PDS5A, RAN, CREB1, ATR, SMC3, CDK2, ATRX, MSL3, RFC5, RFC3, ORC3L, RFC4, RFC1, PSEN1, RFC2, PCNA, CLIP1, ORC5L, H3F3B, SMARCA4	624	386	12782	2.3880280988441607	6.439843460026573E-5	6.440030089760462E-6	1.8112715995943773E-4
GOTERM_BP_FAT	GO:0006396~RNA processing	58	7.204968944099378	1.309910859731553E-7	NCBP1, PRPF4B, SNRPD1, SYNCRIP, SKIV2L2, WTAP, RBM9, YBX1, PNN, NONO, SFRS7, PRMT5, LSM4, MAGOHB, FTSJ1, SRPK2, SNRPA1, EXOSC9, MAGOH, PTBP1, EXOSC2, MBNL1, CDC5L, SFRS1, SFRS3, HNRNPU, SFRS2, HNRPDL, SIP1, THOC2, FUS, POLR2K, WBP11, DIMT1L, HNRNPM, HNRNPF, NUDT21, PRKRA, HNRNPD, DHX15, SFRS2IP, HNRNPC, GEMIN4, PRPF40A, CSTF2, RTCD1, GRSF1, SNW1, PRPF18, DDX5, SLBP, PAPOLA, UPF3B, HNRNPH2, NOLC1, HNRNPH1, DUS4L, UTP14A	683	547	13528	2.100165684781358	3.7796885066276875E-4	1.1455701016127584E-5	2.3485419549107434E-4
GOTERM_CC_FAT	GO:0000502~proteasome complex	16	1.9875776397515528	1.537254041794434E-7	RAD23B, IDE, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, UCHL5, PSME3, PSMD4, PSMD6	624	61	12782	5.372845733501471	7.901174223168272E-5	7.183143639677425E-6	2.2223015504474475E-4
GOTERM_MF_FAT	GO:0043566~structure-specific DNA binding	25	3.1055900621118013	1.583647845785977E-7	XRCC5, RAD23B, CNBP, WBP11, RPA4, POT1, YBX1, RPA1, FUBP1, MCM7, ZNF148, SAFB, MYC, FEN1, MSH6, SSBP1, MSH3, MSH2, SUB1, CREB1, MCM4, HNRPDL, TDP1, PCNA, HSPD1	641	145	12983	3.492118995104632	1.4552665855749325E-4	1.3230571437872207E-5	2.475169843640934E-4
KEGG_PATHWAY	hsa03030:DNA replication	14	1.7391304347826086	1.6354776886021745E-7	SSBP1, POLA1, MCM4, RPA4, RFC5, PRIM1, RPA1, RFC3, RFC4, MCM7, RFC1, RFC2, PCNA, FEN1	330	36	5085	5.992424242424243	2.5840215732486627E-5	1.2920191331922126E-5	1.9705740035291797E-4
GOTERM_BP_FAT	GO:0015931~nucleobase, nucleoside, nucleotide and nucleic acid transport	22	2.732919254658385	1.833441973447121E-7	ENY2, NCBP1, NUP98, RAN, MAGOH, EIF5A, NUP155, VDAC3, NXT2, SENP2, HHEX, TMEM48, UPF3B, NUP205, DDX19B, NPM1, NUP50, MAGOHB, GLE1, RANBP2, THOC2, TPR	683	113	13528	3.856178494149963	5.289914368119542E-4	1.556256720036675E-5	3.287180541433621E-4
GOTERM_CC_FAT	GO:0030529~ribonucleoprotein complex	54	6.70807453416149	1.8706147611303037E-7	NCBP1, MRPL42, PRPF4B, SNRPD1, SYNCRIP, SKIV2L2, YBX1, MRPS30, PNN, EDC3, LSM4, MRPL39, API5, SNRPA1, MAGOH, PTBP1, MRPL9, MRPS7, CDC5L, SFRS1, HNRNPU, HNRPDL, PSMA1, EIF2S1, UBC, SRP72, SIP1, MRPS15, STAU1, HNRNPM, MRPL13, HNRNPF, NPM1, RPL3, MRPL19, HNRNPD, DHX15, MRPL18, TAF9, HNRNPC, GEMIN4, HSPA8, ACTB, MRPS28, ILF3, SNW1, PRPF18, DDX5, SLBP, HNRNPH2, ILF2, RHEB, HNRNPH1, UTP14A	624	515	12782	2.147834204630321	9.614498547616535E-5	8.012435208759605E-6	2.704217414883914E-4
KEGG_PATHWAY	hsa04110:Cell cycle	26	3.229813664596273	2.5766900447977343E-7	YWHAZ, PRKDC, ANAPC10, CDC16, CCNE2, ORC2L, MCM7, MYC, CUL1, BUB3, STAG2, TFDP1, CDC6, ATR, SKP1, YWHAE, MCM4, CDC27, CDK2, SMC3, CDKN1C, ORC3L, YWHAH, YWHAQ, PCNA, ORC5L	330	125	5085	3.2050909090909085	4.0710879240402065E-5	1.3570477237156986E-5	3.104631638550792E-4
GOTERM_BP_FAT	GO:0051028~mRNA transport	19	2.360248447204969	2.582007533408879E-7	ENY2, NCBP1, NUP98, MAGOH, EIF5A, NUP155, NXT2, SENP2, HHEX, TMEM48, UPF3B, NUP205, DDX19B, NUP50, MAGOHB, GLE1, RANBP2, THOC2, TPR	683	87	13528	4.3256087915046875	7.44889901992063E-4	2.129027251096538E-5	4.6292817906801176E-4
GOTERM_BP_FAT	GO:0006260~DNA replication	29	3.602484472049689	3.027738302282759E-7	NUP98, POLA1, POT1, RPA4, CCNE2, RPA1, PRIM1, ORC2L, SET, MCM7, FEN1, CDC6, RBBP4, SSBP1, ATR, MCM4, CDK2, RAD1, RFC5, RFC3, ORC3L, RFC4, RFC1, RFC2, RRM1, PCNA, TOP3A, ORC5L, RAD17	683	190	13528	3.023133235724744	8.734237495542363E-4	2.4272077826292815E-5	5.428430521758898E-4
SP_PIR_KEYWORDS	P-loop	20	2.484472049689441	3.078628204944522E-7	ABCE1, DNM1L, ABCF2, RAB9A, GNAI3, MAT2A, RAB4A, AK2, ARF6, DDX5, RAB1A, HNRNPU, DDX18, RFC1, ARF3, RRAS2, ARF4, RAB5A, RHEB, ABCC1	802	116	19235	4.1351362971880645	1.588446226666873E-4	1.0590426575030065E-5	4.4529746894284017E-4
GOTERM_BP_FAT	GO:0006974~response to DNA damage stimulus	44	5.46583850931677	3.304210719772972E-7	XRCC5, RAD23B, MORF4, POLA1, PRKDC, FOXO3, RPA1, NONO, SUMO1, CHD1L, MCM7, TLK2, FOXO3B, FEN1, MSH6, UBE2A, MSH3, LYN, AIFM1, MSH2, USP1, RINT1, BRIP1, ATR, SMC3, SOD2, GTF2H1, RAD1, UBE2N, ATRX, RFC5, MAPK1, RFC3, DCLRE1A, RFC4, RFC1, PSEN1, RFC2, TDP1, UBR5, PCNA, CUL4B, MCTS1, PARP2, RAD17	683	373	13528	2.336451312809361	9.531408436096456E-4	2.5772515752864322E-5	5.924116396993639E-4
GOTERM_BP_FAT	GO:0006886~intracellular protein transport	44	5.46583850931677	3.5600625160251696E-7	BID, RAB3GAP2, NUP98, YWHAZ, DERL1, TIMM17A, SNX2, AKAP12, EIF5A, PEX3, SEC63, SSR1, CSE1L, PEX1, CEP57, NPM1, BCAP29, PPP3CA, RANBP2, CD24, TPR, SEC23IP, AP3B1, SEC23A, RAN, VTI1B, TIMM23, AP4S1, YWHAE, TIMM8A, MAPK1, YWHAH, NUP205, YWHAQ, MGEA5, PCNA, SPTBN1, TOMM22, GOSR2, KPNA4, SRP72, KPNA2, KPNA1, TOB1	683	374	13528	2.3302041167858065	0.001026906595147592	2.7037377245964223E-5	6.382831468032535E-4
GOTERM_BP_FAT	GO:0006605~protein targeting	31	3.8509316770186333	3.869103898606821E-7	BID, YWHAZ, NUP98, TIMM17A, AKAP12, EIF5A, PEX3, SEC63, SSR1, CSE1L, PEX1, CEP57, RANBP2, PPP3CA, TPR, AP3B1, RAN, TIMM23, YWHAE, TIMM8A, MAPK1, NUP205, YWHAQ, MGEA5, SPTBN1, TOMM22, SRP72, KPNA4, KPNA2, KPNA1, TOB1	683	215	13528	2.8558548128979537	0.0011160004089343367	2.8630964512998958E-5	6.936909547339276E-4
GOTERM_CC_FAT	GO:0005694~chromosome	49	6.086956521739131	4.844318930719104E-7	XRCC5, PRPF4B, MORF4, CBX3, CBX1, HMGN4, PRIM1, MCM7, H2AFV, TPR, STAG2, UBE2A, RBBP4, RAN, CDK2, RFC5, RFC3, RFC4, RFC1, PSEN1, RFC2, TOP3A, ORC5L, CLIP1, SMARCA4, NUP98, POLA1, POT1, RPA4, SUMO3, RPA1, SUMO2, ORC2L, CDYL, HNRNPD, PAFAH1B1, ZWILCH, BUB3, MSH6, TCP1, SMCHD1, PDS5A, CREB1, ATR, SMC3, ATRX, MSL3, ORC3L, PCNA, H3F3B	624	460	12782	2.1819885730211817	2.489670558935009E-4	1.915351297954171E-5	7.003080312983911E-4
GOTERM_BP_FAT	GO:0006511~ubiquitin-dependent protein catabolic process	33	4.099378881987578	5.467528794256703E-7	RAD23B, DERL1, ANAPC10, CDC16, ARIH1, UBE2D3, PSMD4, PSMD6, USP34, CUL1, BUB3, TBL1XR1, UBE2A, USP1, ERLIN1, SKP1, UBE2H, CDC27, PSMA2, PSMA1, PSMC6, PSMD12, PSMA5, PSMD11, PSMC3, PSMD10, UBR5, PSMC2, PSMA3, UBC, UCHL5, PSME3, CUL4B	683	242	13528	2.70091840809264	0.0015766849655626247	3.9447452962804164E-5	9.80270945749595E-4
GOTERM_BP_FAT	GO:0007049~cell cycle	72	8.944099378881988	6.267887397643083E-7	CDC16, WTAP, CCNE2, MCM7, PSMD4, RANBP1, TLK2, PSMD6, MYC, STAG2, CUL1, CDC6, RBBP4, CGRRF1, RAN, RINT1, CDC5L, SKP1, CDK2, PSMA2, RAD1, MAPK1, PSMA1, HHEX, DCLRE1A, CHMP1B, PSMA5, PSMA3, UBC, TOP3A, CLIP1, PSME3, MAPRE1, KPNA2, MCTS1, DST, RAD17, EID1, POLA1, ANAPC10, TCF7L2, CCNG2, RPA1, NUMA1, TUBB, NIPBL, NPM1, PAFAH1B1, PPP3CA, ZWILCH, BUB3, TFDP1, CREBL2, MSH6, PDS5A, MSH2, ILF3, ATR, CDC27, SMC3, CDKN1C, PSMC6, PSMD12, NOLC1, PSMC3, PSMD11, PSMC2, PTP4A1, PSMD10, CUL4B, APBB2, CALM1	683	776	13528	1.8377382982898374	0.0018072777731428236	4.4118852831509514E-5	0.0011237661430518742
GOTERM_CC_FAT	GO:0005635~nuclear envelope	29	3.602484472049689	7.362928967014024E-7	NUP98, POLA1, EIF5A, CBX3, WTAP, ANXA7, SUMO1, CSE1L, DDX19B, NUP50, MRPL19, PAFAH1B1, GLE1, RANBP2, TPR, MYOF, RAN, NUP155, SENP2, NPC1, TMEM48, PSEN1, NUP205, PCNA, KPNA4, KPNA2, MATR3, UBXN4, KPNA1	624	205	12782	2.897732958098812	3.7838308326398895E-4	2.7032112354885562E-5	0.001064403402306624
GOTERM_BP_FAT	GO:0070727~cellular macromolecule localization	46	5.714285714285714	9.305357119132757E-7	BID, RAB3GAP2, NUP98, YWHAZ, DERL1, TIMM17A, SNX2, AKAP12, EIF5A, PEX3, SEC63, STAU1, SSR1, CSE1L, PEX1, CEP57, SH3GLB1, NPM1, BCAP29, PPP3CA, RANBP2, CD24, TPR, SEC23IP, AP3B1, SEC23A, RAN, VTI1B, TIMM23, AP4S1, YWHAE, TIMM8A, MAPK1, YWHAH, NUP205, YWHAQ, MGEA5, PCNA, SPTBN1, TOMM22, GOSR2, KPNA4, SRP72, KPNA2, KPNA1, TOB1	683	414	13528	2.2007483325199284	0.0026819245115036194	6.39390823363728E-5	0.0016683481578239068
GOTERM_BP_FAT	GO:0033554~cellular response to stress	57	7.080745341614906	9.401230945947691E-7	XRCC5, MORF4, FOXO3, PRDX3, NONO, MCM7, ATG5, TLK2, FOXO3B, EIF2B3, SYK, UBE2A, LYN, AIFM1, USP1, RINT1, GTF2H1, UBE2N, RFC5, RAD1, MAPK1, RFC3, DCLRE1A, MAP4K5, RFC4, PSEN1, RFC1, RFC2, EIF2S1, UBR5, MAPK9, MCTS1, RAD17, RAD23B, CAV1, DERL1, ATG12, PTPLAD1, POLA1, PRKDC, RPA1, SUMO1, CHD1L, MYOF, FEN1, MSH6, MSH3, MSH2, MAP2K4, BRIP1, ATR, SMC3, SOD2, ATRX, TDP1, PCNA, CUL4B, PARP2	683	566	13528	1.9946711918422673	0.0027095191352551895	6.309560302519834E-5	0.0016855371433921462
GOTERM_CC_FAT	GO:0012505~endomembrane system	70	8.695652173913043	9.46055066351115E-7	SYT1, TUSC3, RAB9A, LDLR, CBX3, EIF5A, ALG6, WTAP, SSR1, ACTR3, PICALM, RC3H2, PIGC, ASPH, RANBP2, GLE1, TPR, DLG1, SEC23A, SCAMP1, SPTLC1, SPTLC2, RAN, SLC33A1, ERLIN1, SENP2, C14ORF147, MAGT1, NPC1, PSEN1, SQLE, VAMP7, NCK1, NUP205, RAB5A, RAB14, KPNA4, KPNA2, MATR3, KPNA1, CAV2, CAV1, NUP98, DERL1, CNIH, POLA1, FKBP1A, LMAN1, ANXA7, SUMO1, TMED2, CSE1L, DDX19B, NUP50, MRPL19, PAFAH1B1, B3GNT2, GAD1, MYOF, PHLDA1, SEC11A, NUP155, AP4S1, LAMP2, TMEM48, PCNA, GOSR2, HSPD1, SPCS2, UBXN4	624	782	12782	1.8336038428749426	4.861543228217302E-4	3.2417643480053826E-5	0.0013676389041039627
GOTERM_CC_FAT	GO:0005643~nuclear pore	17	2.111801242236025	1.0264219590018416E-6	NUP98, RAN, EIF5A, NUP155, SENP2, SUMO1, TMEM48, CSE1L, DDX19B, NUP205, NUP50, KPNA4, GLE1, RANBP2, TPR, KPNA2, KPNA1	624	79	12782	4.407943849399546	5.27442011210133E-4	3.2973278724313104E-5	0.001483818325109798
UP_SEQ_FEATURE	nucleotide phosphate-binding region:ATP	73	9.06832298136646	1.2256415552500543E-6	PRPF4B, NUAK1, CASK, SKIV2L2, MTHFD1, MAP3K7, DDX18, MCM7, PEX1, TLK2, KIF2A, SYK, SRPK2, CDC6, LYN, BRAF, ROCK1, HKDC1, MCM4, HNRNPU, CDK2, RFC5, MAPK1, ATP6V1A, MAP4K5, RFC4, RFC1, RFC2, NAV2, RIOK3, MAPK9, ORC5L, RIPK2, YME1L1, RAD17, SMARCA4, PRPS1, MAPKAPK5, UBA6, GALK2, MTHFS, PTK2, CHD1L, DDX3X, DDX19B, DHX15, PRKAA1, TAF9, STK38L, CSNK1A1, MSH6, MSH3, MAT2A, MSH2, RYK, PDK3, MET, MAP2K4, BRIP1, ATAD2, AK2, ACLY, DDX5, SMC3, GART, ATRX, RPS6KA3, PSMC6, PSMC3, FYN, PSMC2, PGK1, BMPR1A	802	962	19113	1.8084324013251696	0.0026292172120827573	0.0013154738417555656	0.0021248139145946254
GOTERM_CC_FAT	GO:0005681~spliceosome	22	2.732919254658385	1.5224135116043034E-6	SNRPA1, PRPF4B, MAGOH, SNRPD1, SYNCRIP, SKIV2L2, SNW1, CDC5L, SFRS1, PRPF18, DDX5, HNRNPU, PNN, HNRNPM, HNRNPF, DHX15, RHEB, HNRNPC, HNRNPH1, SIP1, API5, GEMIN4	624	132	12782	3.413995726495726	7.82215050795787E-4	4.602959593613676E-5	0.00220082735825633
GOTERM_CC_FAT	GO:0005663~DNA replication factor C complex	6	0.7453416149068323	1.5598462083920308E-6	RFC5, RFC3, RFC4, RFC1, RFC2, PCNA	624	6	12782	20.48397435897436	8.014402515093E-4	4.454131780828874E-5	0.0022549401456517515
GOTERM_BP_FAT	GO:0034613~cellular protein localization	45	5.590062111801243	1.8542564853343461E-6	BID, RAB3GAP2, NUP98, YWHAZ, DERL1, TIMM17A, SNX2, AKAP12, EIF5A, PEX3, SEC63, SSR1, CSE1L, PEX1, CEP57, SH3GLB1, NPM1, BCAP29, PPP3CA, RANBP2, CD24, TPR, SEC23IP, AP3B1, SEC23A, RAN, VTI1B, TIMM23, AP4S1, YWHAE, TIMM8A, MAPK1, YWHAH, NUP205, YWHAQ, MGEA5, PCNA, SPTBN1, TOMM22, GOSR2, KPNA4, SRP72, KPNA2, KPNA1, TOB1	683	411	13528	2.168620619636426	0.005337096002576813	1.2161508560770695E-4	0.003324451887243285
SP_PIR_KEYWORDS	translocation	15	1.8633540372670807	1.8797415073462386E-6	NUP98, TIMM17A, EIF5A, TIMM23, NUP155, TIMM8A, SENP2, TMEM48, DDX19B, NUP205, NUP50, TOMM22, GLE1, RANBP2, TPR	802	74	19235	4.861579160207589	9.694772823576336E-4	6.061988312888733E-5	0.0027188579532988477
GOTERM_BP_FAT	GO:0017038~protein import	22	2.732919254658385	2.316068465937934E-6	BID, YWHAZ, NUP98, RAN, TIMM17A, PEX3, TIMM23, TIMM8A, MAPK1, CEP57, PEX1, CSE1L, NUP205, SPTBN1, TOMM22, KPNA4, RANBP2, PPP3CA, TPR, KPNA2, KPNA1, TOB1	683	131	13528	3.326321907167525	0.006661891882952076	1.485263318300456E-4	0.0041524072561416325
SP_PIR_KEYWORDS	Spliceosome	19	2.360248447204969	2.3495389817247586E-6	SNRPA1, PRPF4B, MAGOH, SNRPD1, SYNCRIP, SKIV2L2, SNW1, CDC5L, SFRS1, PRPF18, DDX5, HNRNPU, PNN, HNRNPM, HNRNPF, HNRNPC, HNRNPH1, SIP1, GEMIN4	802	120	19235	3.797433499584372	0.0012116289230368338	7.131295939288851E-5	0.0033983622314548434
GOTERM_CC_FAT	GO:0046930~pore complex	18	2.236024844720497	2.9090982051940853E-6	NUP98, RAN, EIF5A, NUP155, VDAC3, SENP2, SUMO1, TMEM48, CSE1L, DDX19B, NUP205, NUP50, KPNA4, GLE1, RANBP2, TPR, KPNA2, KPNA1	624	95	12782	3.881174089068826	0.0014941612803116566	7.869577976882258E-5	0.004205403549073505
GOTERM_BP_FAT	GO:0009057~macromolecule catabolic process	70	8.695652173913043	3.2023816446516935E-6	NCBP1, LDLR, IDE, CDC16, FBXO28, PSMD4, RANBP2, PSMD6, MYC, CUL1, NFX1, ABCE1, TBL1XR1, UBE2A, ADAM10, SOCS2, AIFM1, MAGOH, USP1, HERC4, ERLIN1, UBE2H, SKP1, GTF2H1, UBE2N, SENP2, PSMA2, WDR48, GNS, SENP3, PSMA1, PJA1, PSEN1, TRIM33, PSMA5, UBR5, PSMA3, UBC, UCHL5, MGEA5, PSME3, YME1L1, ADAM19, RAD23B, DERL1, ATG12, UBA6, ANAPC10, FKBP1A, RPA1, SUMO3, SUMO2, ARIH1, SUMO1, UBE2D3, HNRNPD, USP34, TPRKB, RNF14, BUB3, FEN1, CDC27, PSMC6, UPF3B, PSMD12, PSMC3, PSMD11, PYGL, PSMC2, PSMD10, CUL4B	683	781	13528	1.7752515358355376	0.009199511394641258	2.008947793491478E-4	0.005741407567816381
GOTERM_BP_FAT	GO:0010604~positive regulation of macromolecule metabolic process	75	9.316770186335404	3.202641431497009E-6	ENY2, NCBP1, IL6ST, PRKAG2, CASK, RHOQ, EIF5A, CDC16, FOXO3, MED21, FNTA, ZNF148, PSMD4, PSMD6, FOXO3B, FOSL1, MYC, CUL1, SYK, TBL1XR1, LYN, RAN, STRN3, SKP1, PROX1, CDK2, GTF2H1, UBE2N, MED6, PSMA2, MAPK1, MED7, PSMA1, HHEX, PSEN1, PSMA5, MED17, PSMA3, UBC, MGEA5, MAPK9, PSME3, SMARCA4, CNBP, CAV1, ABLIM3, PRKDC, ANAPC10, FKBP1A, NFYB, NFYA, TCF7L2, POT1, NPAS2, TAF9, CD24, RUNX1, RNF14, PLAGL2, BMP4, CREB1, ILF3, DDX5, CDC27, STAT3, PSMC6, YWHAH, ILF2, PSMD12, YAF2, PSMC3, PSMD11, PSMC2, PSMD10, BMP7, BMPR1A	683	857	13528	1.7333782082274816	0.009200254244329464	1.9663679151649127E-4	0.0057418733154901425
SP_PIR_KEYWORDS	mental retardation	14	1.7391304347826086	3.24867276401094E-6	RAB3GAP2, TUSC3, ALDH18A1, ATP6AP2, CASK, AMMECR1, ATRX, MAGT1, RPS6KA3, UPF3B, SRPX2, DLG3, CUL4B, FTSJ1	802	67	19235	5.011538318383146	0.001674913633100239	9.312443415854244E-5	0.004698836700889331
SP_PIR_KEYWORDS	ubl conjugation	50	6.211180124223603	3.248753882140934E-6	XRCC5, SYNCRIP, YBX1, FUBP1, RANBP9, ATG5, BAG1, H2AFV, PEX1, NGFRAP1, RANBP2, CUL1, NFX1, SYK, RBBP4, RAN, USP1, UBE2N, SENP2, PSMA1, PJA1, MED7, UBC, DST, EID1, SLC38A2, MCL1, TCF7L2, SUMO3, HNRNPM, SUMO2, TUBB, SET, HNRNPF, NPM1, RCHY1, HNRNPC, RNF14, BUB3, C21ORF59, TMBIM6, DRG2, STAT1, PAPOLA, PSMC3, PKP4, PCNA, H3F3B, CUL4B, HDAC9, CALM1	802	588	19235	2.0394379697015967	0.0016749554200742311	8.82255671705856E-5	0.004698954026471913
GOTERM_BP_FAT	GO:0006913~nucleocytoplasmic transport	24	2.981366459627329	3.4043859559589124E-6	NCBP1, NUP98, RAN, EIF5A, NUP155, MAPK1, HHEX, SET, CEP57, CSE1L, NUP205, DDX19B, NPM1, ANP32A, SPTBN1, PPP3CA, KPNA4, GLE1, RANBP2, THOC2, TPR, KPNA2, KPNA1, TOB1	683	156	13528	3.047189998873747	0.009776966232576623	2.0466810664487856E-4	0.006103561673542757
SP_PIR_KEYWORDS	nuclear pore complex	11	1.3664596273291925	4.032983496745675E-6	SENP2, NUP98, TMEM48, NUP205, DDX19B, NUP50, EIF5A, GLE1, RANBP2, NUP155, TPR	802	40	19235	6.595542394014963	0.002078859852148507	1.0404577089706546E-4	0.005833222422535478
SMART	SM00360:RRM	26	3.229813664596273	4.059808155564399E-6	FUS, ENOX2, SYNCRIP, RBM9, NONO, SFRS7, HNRNPM, SAFB, HNRNPF, HNRNPD, HNRNPC, RBM12, EWSR1, CSTF2, PTBP1, GRSF1, ELAVL1, SFRS1, SFRS3, SFRS2, HNRPDL, EIF4B, HNRNPH2, LARP4, HNRNPH1, MATR3	393	211	9079	2.846664978353412	9.77937258953565E-4	9.77937258953565E-4	0.005243521585007738
GOTERM_BP_FAT	GO:0051169~nuclear transport	24	2.981366459627329	4.244262553289867E-6	NCBP1, NUP98, RAN, EIF5A, NUP155, MAPK1, HHEX, SET, CEP57, CSE1L, NUP205, DDX19B, NPM1, ANP32A, SPTBN1, PPP3CA, KPNA4, GLE1, RANBP2, THOC2, TPR, KPNA2, KPNA1, TOB1	683	158	13528	3.008617973571548	0.01217425448210585	2.499476909872955E-4	0.007609282386578098
GOTERM_BP_FAT	GO:0006261~DNA-dependent DNA replication	14	1.7391304347826086	4.670099955429468E-6	POLA1, MCM4, RPA4, PRIM1, CCNE2, RPA1, RFC3, ORC2L, RFC4, MCM7, RFC1, TOP3A, ORC5L, FEN1	683	58	13528	4.780936032715706	0.013387519194789421	2.6952247115163974E-4	0.008372710405935013
GOTERM_CC_FAT	GO:0044454~nuclear chromosome part	20	2.484472049689441	6.578986239654331E-6	XRCC5, MSH6, TCP1, RBBP4, MORF4, POLA1, CBX3, ATR, CBX1, POT1, RPA4, SMC3, RPA1, PRIM1, ATRX, ORC2L, MCM7, ORC3L, ORC5L, H3F3B	624	122	12782	3.3580285834384194	0.0033758988472241125	1.690662092469486E-4	0.00951037297263202
GOTERM_BP_FAT	GO:0006281~DNA repair	34	4.22360248447205	6.616673547184136E-6	XRCC5, RAD23B, MORF4, POLA1, PRKDC, RPA1, NONO, SUMO1, CHD1L, FEN1, MSH6, UBE2A, MSH3, MSH2, USP1, BRIP1, ATR, SMC3, SOD2, GTF2H1, RAD1, UBE2N, RFC5, ATRX, RFC3, DCLRE1A, RFC4, RFC1, RFC2, TDP1, PCNA, CUL4B, PARP2, RAD17	683	284	13528	2.371228837151754	0.018914613591223595	3.743570291989684E-4	0.01186239677986034
GOTERM_CC_FAT	GO:0044429~mitochondrial part	55	6.832298136645963	7.027917121160237E-6	UQCRC2, HCCS, MRPL42, ABCF2, TIMM17A, MCCC2, ATP5S, NARS2, MRPL39, SSBP1, LYN, AIFM1, TMEM70, MRPL9, DARS2, TIMM23, TIMM8A, NNT, PSEN1, DLD, TOMM22, AKAP1, BID, ME2, MRPS15, ALDH18A1, MCL1, GLUD2, GLUD1, BCL2L1, MRPL13, ACSL1, SH3GLB1, SLC25A46, MRPL18, AGK, FH, ETFA, GPD2, DNM1L, MRPS28, PDK3, AK2, DLAT, VDAC3, IDH3A, SOD2, PPIF, SLC25A14, FYN, GLS, SDHC, NDUFV2, BIK, HSPD1	624	595	12782	1.893476621417798	0.0036058453633193155	1.7200244845272383E-4	0.010159302471113296
INTERPRO	IPR003959:ATPase, AAA-type, core	12	1.4906832298136645	8.916118905990232E-6	RFC5, CDC6, PSMC6, RFC4, PEX1, RFC1, PSMC3, RFC2, PSMC2, ATAD2, TAF9, YME1L1	753	49	16659	5.418001463533621	0.0120703696251796	0.0120703696251796	0.014640475224036997
SP_PIR_KEYWORDS	methylation	27	3.354037267080745	9.877186667570841E-6	FUS, SNRPD1, RHOQ, TUBB, GORASP2, RALB, HNRNPD, RUNX1, GAPDH, EWSR1, RAP2B, ACTB, RAP2C, RAB4A, ELAVL1, ILF3, DDX5, SFRS1, HNRNPU, HNRPDL, HNRNPH2, RRAS2, RAB14, RHEB, H3F3B, HNRNPH1, CALM1	802	242	19235	2.675877455122524	0.005083687589320984	2.4266833655128828E-4	0.014285592796725588
INTERPRO	IPR000504:RNA recognition motif, RNP-1	26	3.229813664596273	1.0232842431310593E-5	FUS, ENOX2, SYNCRIP, RBM9, NONO, SFRS7, HNRNPM, SAFB, HNRNPF, HNRNPD, HNRNPC, RBM12, EWSR1, CSTF2, PTBP1, GRSF1, ELAVL1, SFRS1, SFRS3, SFRS2, HNRPDL, EIF4B, HNRNPH2, LARP4, HNRNPH1, MATR3	753	211	16659	2.7261192198032513	0.013840529529579482	0.006944376950404396	0.016802395377246704
GOTERM_BP_FAT	GO:0000278~mitotic cell cycle	40	4.968944099378882	1.0333763154753836E-5	POLA1, ANAPC10, CDC16, CCNG2, NUMA1, TUBB, NIPBL, PSMD4, PAFAH1B1, PPP3CA, PSMD6, ZWILCH, STAG2, CUL1, BUB3, CDC6, PDS5A, RAN, SKP1, CDC27, SMC3, CDK2, PSMA2, CDKN1C, PSMA1, DCLRE1A, PSMC6, NOLC1, PSMD12, PSMA5, PSMD11, PSMC3, PSMD10, PSMC2, PSMA3, UBC, CLIP1, PSME3, MAPRE1, KPNA2	683	370	13528	2.1412686478572276	0.029383065355120808	5.73362383369802E-4	0.018525825876969382
SP_PIR_KEYWORDS	isopeptide bond	32	3.9751552795031055	1.1278780645131504E-5	MCL1, ATG12, SYNCRIP, TCF7L2, YBX1, SUMO3, SUMO2, SUMO1, TUBB, SET, ATG5, H2AFV, PEX1, HNRNPF, NPM1, RANBP2, HNRNPC, CUL1, BUB3, C21ORF59, RBBP4, RAN, TMBIM6, STAT1, UBE2N, PSMA1, PAPOLA, PKP4, UBC, PCNA, CUL4B, DST, CALM1	802	319	19235	2.405897482000328	0.005802980917289591	2.645051774963214E-4	0.01631259514307537
SP_PIR_KEYWORDS	phosphotransferase	24	2.981366459627329	1.1473003761759196E-5	ROCK1, LYN, BRAF, RYK, MAPKAPK5, PDK3, PHKA1, MAP2K4, MET, PRKAB1, PRKDC, AK2, CDK2, GALK2, MAP3K7, MAPK1, RPS6KA3, FYN, ADK, PRKAR1A, MAPK9, PIK3CA, PGK1, SYK	802	201	19235	2.8637361819332265	0.005902614616556057	2.5736269835685555E-4	0.01659347997138294
INTERPRO	IPR012677:Nucleotide-binding, alpha-beta plait	26	3.229813664596273	1.2068715795071057E-5	FUS, ENOX2, SYNCRIP, RBM9, NONO, SFRS7, HNRNPM, SAFB, HNRNPF, HNRNPD, HNRNPC, RBM12, EWSR1, CSTF2, PTBP1, GRSF1, ELAVL1, SFRS1, SFRS3, SFRS2, HNRPDL, EIF4B, HNRNPH2, UPF3B, HNRNPH1, MATR3	753	213	16659	2.7005218562370232	0.016303328481587442	0.005464246432467124	0.019816631142322017
SMART	SM00382:AAA	20	2.484472049689441	1.2771150264342693E-5	CDC6, ABCE1, ABCF2, ATAD2, MCM4, RFC5, RFC3, PSMC6, MCM7, RFC4, PEX1, RFC1, RFC2, NAV2, PSMC3, PSMC2, DHX15, ABCC1, YME1L1, RAD17	393	144	9079	3.2085807181227026	0.0030731350913038025	0.0015377498830032588	0.016493963253572108
SP_PIR_KEYWORDS	mitochondrion	62	7.7018633540372665	1.286539539528632E-5	UQCRC2, HCCS, MRPL42, TIMM17A, PRDX3, MRPS30, MTFR1, ACOT9, MCCC2, GSR, ATP5S, NARS2, MRPL39, ABCE1, SSBP1, AIFM1, MRPL9, TMEM70, MRPS7, DARS2, TIMM23, BCL2L13, TIMM8A, MTRR, NNT, DLD, TOMM22, YME1L1, AKAP1, BID, ME2, MRPS15, ALDH18A1, MCL1, GLUD2, GLUD1, BCL2L1, MRPL13, ACSL1, SH3GLB1, SLC25A46, MRPL19, MRPL18, GCSH, AGK, ETFA, FH, GPD2, MRPS28, PDK3, C21ORF33, AK2, DLAT, VDAC3, IDH3A, SOD2, PPIF, SLC25A14, GLS, SDHC, NDUFV2, HSPD1	802	832	19235	1.787253620755803	0.006616599991709382	2.7656952793075895E-4	0.01860713063291941
GOTERM_CC_FAT	GO:0005657~replication fork	10	1.2422360248447204	1.4968960982848652E-5	RFC5, RPA1, PRIM1, RFC3, RFC4, RFC1, RFC2, POLA1, PCNA, RPA4	624	32	12782	6.401241987179487	0.007664579685487505	3.496708296139017E-4	0.02163743182012068
GOTERM_BP_FAT	GO:0044265~cellular macromolecule catabolic process	64	7.950310559006211	1.5189634467764845E-5	NCBP1, LDLR, IDE, CDC16, FBXO28, PSMD4, RANBP2, PSMD6, MYC, CUL1, NFX1, ABCE1, TBL1XR1, UBE2A, ADAM10, SOCS2, AIFM1, MAGOH, USP1, HERC4, ERLIN1, UBE2H, SKP1, GTF2H1, UBE2N, WDR48, SENP2, PSMA2, SENP3, PSMA1, PJA1, PSEN1, TRIM33, PSMA5, UBR5, PSMA3, UBC, UCHL5, PSME3, ADAM19, RAD23B, DERL1, ATG12, UBA6, ANAPC10, SUMO3, RPA1, SUMO2, ARIH1, SUMO1, UBE2D3, HNRNPD, USP34, RNF14, BUB3, FEN1, CDC27, PSMC6, UPF3B, PSMD12, PSMC3, PSMD11, PSMC2, PSMD10, CUL4B	683	725	13528	1.7484566062503157	0.042890637825287015	8.267828946980638E-4	0.027230056788385415
SP_PIR_KEYWORDS	DNA damage	24	2.981366459627329	1.584394440678083E-5	XRCC5, RAD23B, MSH6, UBE2A, MSH3, MSH2, USP1, MORF4, PRKDC, BRIP1, ATR, SMC3, GTF2H1, NONO, RAD1, UBE2N, ATRX, DCLRE1A, CHD1L, TDP1, TLK2, CUL4B, MCTS1, RAD17	802	205	19235	2.807858402773554	0.008142211241604747	3.26968137482897E-4	0.022914525590356227
SP_PIR_KEYWORDS	endoplasmic reticulum	55	6.832298136645963	1.664101822946488E-5	CYB5R4, RAB9A, TUSC3, SGPP1, DNAJC10, SYNCRIP, PDIA6, EIF5A, ALG6, C14ORF1, CANX, RAB1A, SSR1, PGRMC1, PIGC, ASPH, DLG1, SEC23A, SPTLC1, SPTLC2, AIFM1, SLC33A1, RINT1, CNPY2, ERLIN1, C14ORF147, MAGT1, PSEN1, SQLE, VAMP7, NCK1, TMCO1, DEGS1, ERMP1, CNBP, DERL1, CNIH, LMAN1, SEC63, STAU1, CALU, ACSL1, SET, BCAP29, SEC23IP, EBP, SEC11A, PTP4A1, YIPF5, SPCS2, PDCD6, UBXN4, ALG13, RCN2, SEL1L	802	713	19235	1.8500820179565114	0.00855007526707241	3.3020842509645654E-4	0.024067175583220024
GOTERM_BP_FAT	GO:0022402~cell cycle process	53	6.583850931677018	1.82490764164523E-5	CDC16, RANBP1, PSMD4, PSMD6, MYC, CUL1, STAG2, CDC6, CGRRF1, RAN, SKP1, CDK2, RAD1, PSMA2, PSMA1, DCLRE1A, PSMA5, PSMA3, UBC, TOP3A, CLIP1, PSME3, MAPRE1, KPNA2, DST, POLA1, ANAPC10, TCF7L2, CCNG2, RPA1, NUMA1, TUBB, NIPBL, NPM1, PAFAH1B1, PPP3CA, ZWILCH, BUB3, MSH6, PDS5A, MSH2, ILF3, CDC27, SMC3, CDKN1C, PSMC6, NOLC1, PSMD12, PSMC3, PSMD11, PSMD10, PSMC2, APBB2	683	565	13528	1.8579769108177095	0.051304423323334514	9.748451794853175E-4	0.03271379045752809
GOTERM_CC_FAT	GO:0044451~nucleoplasm part	51	6.3354037267080745	1.8894810276539667E-5	ENY2, MORF4, MED21, PNN, MCM7, OGT, MYC, TBL1XR1, RBBP4, MAGOH, CDC5L, SFRS1, GTF2B, CDK2, SFRS2, GTF2H1, MED6, MED7, TAF12, MED17, C19ORF2, TOP3A, SIP1, HOXA11, CREM, TAF9B, PRKDC, WBP11, NFYB, NFYA, TRRAP, TCF7L2, RPA1, SUMO1, NPAS2, DDX3X, NUDT21, NPM1, TAF9, GEMIN4, GTF3C4, GTF3C3, TFDP1, PRPF40A, ACTB, POLR3K, SUB1, CREB1, PRPF18, POLR3C, HDAC9	624	555	12782	1.8823111573111573	0.009665014837023755	4.221727832787181E-4	0.02731147279648738
SP_PIR_KEYWORDS	transit peptide	41	5.093167701863354	2.126289731047461E-5	UQCRC2, MRPL42, ME2, MRPS15, GLUD2, GLUD1, PRDX3, ACOT9, MCCC2, GSR, AGPS, ATP5S, NARS2, MRPL19, MRPL18, GCSH, AGK, ETFA, FH, GPD2, MRPS28, SSBP1, AIFM1, PDK3, C21ORF33, MRPL9, TMEM70, DLAT, MRPS7, DARS2, IDH3A, SOD2, MTRR, PPIF, NNT, GLS, SDHC, NDUFV2, DLD, HSPD1, AKAP1	802	476	19235	2.065830696368323	0.010911801299225088	4.062793594570291E-4	0.030750640012999764
GOTERM_BP_FAT	GO:0010608~posttranscriptional regulation of gene expression	27	3.354037267080745	2.243032926282109E-5	NCBP1, EIF5, PRKDC, SYNCRIP, EIF5A, YBX1, HRSP12, PRKRA, HNRNPD, EIF1, EIF2B3, GTPBP4, MAGOH, PAIP1, ELAVL1, ANKHD1, SELT, HNRNPU, EIF4B, LOC645139, MAPK1, EIF4E, SERBP1, NCK1, EIF2S1, NGDN, HSPD1, GATC	683	211	13528	2.534511112807311	0.06268385865094261	0.0011763013648024012	0.04020779496182181
GOTERM_CC_FAT	GO:0005739~mitochondrion	84	10.434782608695652	2.2457830951080932E-5	HCCS, UQCRC2, ACOX1, MRPL42, TUSC3, ABCF2, TIMM17A, PRDX3, MRPS30, MTFR1, ACOT9, MTHFD1, GSR, MCCC2, AGPS, NARS2, ATP5S, MRPL39, ABCE1, LYN, SSBP1, AIFM1, HKDC1, MRPL9, TMEM70, DARS2, MRPS7, BCL2L13, TIMM23, MTRR, TIMM8A, ATP6V1A, NNT, PSEN1, DLD, TOMM22, YME1L1, AKAP1, BID, CAV2, CAV1, YWHAZ, ME2, MRPS15, ALDH18A1, MCL1, GLUD2, GLUD1, BCL2L1, MRPL13, ACSL1, SH3GLB1, SLC25A46, MRPL19, GCSH, MRPL18, PPP3CA, GAD1, AGK, FEN1, ETFA, FH, GPD2, DNM1L, MRPS28, PDK3, CREB1, C21ORF33, AK2, ILF3, DLAT, VDAC3, YWHAE, IDH3A, SOD2, PPIF, SLC25A14, FYN, SDHC, GLS, NDUFV2, BIK, HSPD1, PERP	624	1087	12782	1.5829382209327012	0.011477084681643657	4.8086162938032473E-4	0.03246085708381585
INTERPRO	IPR003593:ATPase, AAA+ type, core	20	2.484472049689441	2.6079544054901823E-5	CDC6, ABCE1, ABCF2, ATAD2, MCM4, RFC5, RFC3, PSMC6, MCM7, RFC4, PEX1, RFC1, RFC2, NAV2, PSMC3, PSMC2, DHX15, ABCC1, YME1L1, RAD17	753	144	16659	3.0727091633466137	0.034897342225652994	0.00884088801987093	0.04281755294460732
GOTERM_MF_FAT	GO:0003689~DNA clamp loader activity	5	0.6211180124223602	2.8115358764773055E-5	RFC5, RFC3, RFC4, RFC1, RFC2	641	5	12983	20.254290171606865	0.02550742361493863	0.0021508816929242114	0.043934046934435145
GOTERM_MF_FAT	GO:0033170~protein-DNA loading ATPase activity	5	0.6211180124223602	2.8115358764773055E-5	RFC5, RFC3, RFC4, RFC1, RFC2	641	5	12983	20.254290171606865	0.02550742361493863	0.0021508816929242114	0.043934046934435145
GOTERM_BP_FAT	GO:0051096~positive regulation of helicase activity	5	0.6211180124223602	3.074407971235358E-5	MSH6, MSH3, SSBP1, MSH2, POT1	683	5	13528	19.806734992679356	0.08490626652698252	0.0015831878979939429	0.05510684469093308
UP_SEQ_FEATURE	transit peptide:Mitochondrion	40	4.968944099378882	3.566643970432472E-5	UQCRC2, MRPL42, ME2, MRPS15, GLUD2, GLUD1, PRDX3, ACOT9, MCCC2, GSR, ATP5S, NARS2, MRPL19, MRPL18, GCSH, AGK, ETFA, FH, GPD2, MRPS28, SSBP1, AIFM1, PDK3, C21ORF33, MRPL9, TMEM70, MRPS7, DARS2, DLAT, IDH3A, SOD2, MTRR, PPIF, NNT, GLS, SDHC, NDUFV2, DLD, HSPD1, AKAP1	802	467	19113	2.041256601536843	0.07375164536631507	0.025214299253884298	0.06181516206248405
SP_PIR_KEYWORDS	nucleotide binding	16	1.9875776397515528	3.656949526761838E-5	ABCE1, RAB9A, GNAI3, RAB4A, ARF6, DDX5, RAB1A, HNRNPU, DDX18, RFC1, ARF3, RRAS2, ARF4, RAB5A, RHEB, ABCC1	802	107	19235	3.586361199804228	0.018693276921344593	6.737088346921993E-4	0.052881763997392195
GOTERM_BP_FAT	GO:0033043~regulation of organelle organization	27	3.354037267080745	3.658946844967305E-5	CAV2, CAV1, CEP76, RHOQ, ARF6, ANAPC10, CDC16, ARPC5, POT1, DSTN, ACTR3, SET, ARPC2, PRMT5, NPM1, RANBP1, TLK2, TPR, MYC, PROX1, NEBL, UBE2N, ARPC1A, NCK1, SPTBN1, MAPRE1, DST	683	217	13528	2.464432464526925	0.10021473436579653	0.0018509014191842033	0.06558109460197414
GOTERM_MF_FAT	GO:0019904~protein domain specific binding	35	4.3478260869565215	4.0408646946442574E-5	HSP90AB1, YWHAZ, RHOQ, ABI2, CBX3, DAZAP2, HNRNPM, PTK2, WBP5, SRR, TAF9, SYK, TFDP1, RAP2B, SCAMP1, ADAM10, STRN3, LIN7C, CDC5L, YWHAE, PROX1, PTPN12, ELMO2, DOCK4, TJP1, CHMP1B, YWHAH, PSEN1, NCK1, YWHAQ, CLDN1, RIPK2, ADAM19, CRK, CALM1	641	331	12983	2.1416923142182487	0.03645520173411765	0.0028525619116746004	0.06313829327283527
GOTERM_CC_FAT	GO:0005730~nucleolus	59	7.329192546583851	4.335569843089146E-5	S100A4, COPS2, SKIV2L2, CCT2, WTAP, ZNF207, PNN, FUBP1, ZNF148, PGRMC1, SRPK2, GTPBP4, EXOSC9, HKDC1, PTBP1, EXOSC2, CDC5L, MCM4, MAPK1, SENP3, TAF12, NAV2, FLII, RAD17, PNMA1, FUS, POLA1, DIMT1L, HNRNPM, SAFB, HNRNPF, NPM1, RPL3, GEMIN4, BUB3, NMD3, PHLDA1, NKRF, CSTF2, TSR1, SUB1, ZMYM6, PNO1, ILF3, SNW1, DDX5, STAT1, STAT3, CDKN1C, PAPOLA, CCT5, HNRNPH2, NOLC1, ILF2, SPTBN1, DNAJB1, HNRNPH1, UTP14A, PARP2	624	698	12782	1.7314534200279186	0.022038828907252284	8.910152937060545E-4	0.06265811139951616
GOTERM_BP_FAT	GO:0033365~protein localization in organelle	21	2.608695652173913	4.3554042697881875E-5	BID, YWHAZ, NUP98, RAN, TIMM17A, TIMM23, TIMM8A, MAPK1, CEP57, CSE1L, NUP205, SPTBN1, TOMM22, SRP72, KPNA4, RANBP2, PPP3CA, TPR, KPNA2, KPNA1, TOB1	683	146	13528	2.848913937303195	0.11812036858841524	0.002164889525470781	0.07805944031794576
KEGG_PATHWAY	hsa03040:Spliceosome	22	2.732919254658385	4.620543093558861E-5	NCBP1, SNRPA1, MAGOH, SNRPD1, WBP11, SNW1, CDC5L, SFRS1, PRPF18, DDX5, HNRNPU, SFRS3, SFRS2, SFRS7, HNRNPM, DHX15, LSM4, MAGOHB, HNRNPC, THOC2, HSPA8, PRPF40A	330	126	5085	2.6904761904761907	0.007274041912601725	0.001823492102751345	0.05565839615142565
SP_PIR_KEYWORDS	dna repair	22	2.732919254658385	4.9393031535324014E-5	XRCC5, RAD23B, MSH6, UBE2A, MSH3, MSH2, USP1, MORF4, PRKDC, BRIP1, ATR, SMC3, GTF2H1, NONO, RAD1, UBE2N, ATRX, DCLRE1A, CHD1L, TDP1, CUL4B, GAPDH	802	191	19235	2.762530845660717	0.025165371074317044	8.784909258171547E-4	0.07141922937603518
KEGG_PATHWAY	hsa05130:Pathogenic Escherichia coli infection	14	1.7391304347826086	4.9949376283579733E-5	ACTB, YWHAZ, ROCK1, ARPC4, ARPC5, ARPC1A, TUBB, CTTN, FYN, ARPC2, LOC100129652, NCK1, YWHAQ, CLDN1	330	57	5085	3.784688995215311	0.00786113692915369	0.0015771946311470275	0.06016705436091563
GOTERM_CC_FAT	GO:0005625~soluble fraction	33	4.099378881987578	6.023723860886153E-5	RAB3GAP2, CAV2, YWHAZ, CAV1, ATG12, IDE, ABI1, HPRT1, ACP1, RAB1A, ANXA7, WARS, GSR, CTTN, ACSL1, SRR, PAFAH1B1, PPP3CA, ACTB, AIFM1, RAB4A, GYG1, CAPN2, PTPN12, ANXA2, SOD2, MAPK1, CD55, BLMH, PYGL, UBR5, YWHAQ, PRPS1	624	313	12782	2.1596522487097567	0.030488432742978078	0.0011901709230955904	0.08704560428598462
GOTERM_BP_FAT	GO:0030163~protein catabolic process	55	6.832298136645963	6.227461437397291E-5	IDE, CDC16, FBXO28, PSMD4, RANBP2, PSMD6, CUL1, NFX1, TBL1XR1, UBE2A, ADAM10, SOCS2, USP1, HERC4, ERLIN1, UBE2H, SKP1, UBE2N, WDR48, SENP2, PSMA2, SENP3, PSMA1, PJA1, TRIM33, PSEN1, PSMA5, UBR5, PSMA3, UBC, UCHL5, PSME3, YME1L1, ADAM19, RAD23B, DERL1, ATG12, UBA6, ANAPC10, SUMO3, ARIH1, SUMO2, SUMO1, UBE2D3, USP34, TPRKB, RNF14, BUB3, CDC27, PSMC6, PSMD12, PSMC3, PSMD11, PSMD10, PSMC2, CUL4B	683	622	13528	1.7513993964587855	0.16450434668346703	0.003041638265283031	0.11159357651547852
GOTERM_BP_FAT	GO:0051726~regulation of cell cycle	35	4.3478260869565215	6.391951637434883E-5	CAV2, CEP76, ANAPC10, TRRAP, CDC16, PDCD4, CCNG2, CCNE2, FNTA, PRMT5, NPM1, RANBP1, TPR, ZWILCH, MYC, FOSL1, BUB3, HSPA8, DLG1, BMP4, CDC6, GTPBP4, MSH2, RINT1, BRIP1, ATR, PROX1, CDK2, GTF2H1, RAD1, CDKN1C, APBB2, BMP7, RAD17, SMARCA4	683	331	13528	2.094367748470627	0.1684614506250901	0.0030699051779057296	0.11453957944488335
GOTERM_BP_FAT	GO:0006270~DNA replication initiation	7	0.8695652173913043	8.3235321685298E-5	CCNE2, ORC2L, MCM7, POLA1, ORC5L, MCM4, RPA4	683	16	13528	8.665446559297218	0.21355079031774316	0.00393040543164036	0.14912785482422697
GOTERM_CC_FAT	GO:0031090~organelle membrane	82	10.186335403726709	8.82788042828768E-5	HCCS, UQCRC2, ACOX1, SYT1, TUSC3, RAB9A, LDLR, TIMM17A, CBX3, ALG6, PEX3, WTAP, SSR1, ACTR3, PEX1, AGPS, ATP5S, PIGC, ASPH, DLG1, SEC23A, SCAMP1, SPTLC1, LYN, SPTLC2, SLC33A1, TMEM70, VTI1B, ERLIN1, TIMM23, ATP6V1D, TIMM8A, C14ORF147, MAGT1, NNT, PSEN1, SQLE, SCYL2, VAMP7, NCK1, RAB5A, TOMM22, AKAP1, MATR3, BID, CAV2, CAV1, DERL1, ALDH18A1, CNIH, MCL1, FKBP1A, BCL2L1, LMAN1, MTMR2, SUMO1, ACSL1, TMED2, SH3GLB1, SLC25A46, MRPL19, PAFAH1B1, B3GNT2, GAD1, AGK, PHLDA1, GPD2, DNM1L, SEC11A, AK2, VDAC3, SOD2, PPIF, LAMP2, SLC25A14, SDHC, NDUFV2, PCNA, GOSR2, HSPD1, SPCS2, ATP6V0A2	624	1096	12782	1.5325601253977168	0.044363155967033	0.0016792295639754817	0.1275429048372856
GOTERM_BP_FAT	GO:0051603~proteolysis involved in cellular protein catabolic process	53	6.583850931677018	8.980386873495433E-5	IDE, CDC16, FBXO28, PSMD4, RANBP2, PSMD6, CUL1, NFX1, TBL1XR1, UBE2A, ADAM10, SOCS2, USP1, HERC4, ERLIN1, UBE2H, SKP1, UBE2N, WDR48, SENP2, PSMA2, SENP3, PSMA1, PJA1, TRIM33, PSEN1, PSMA5, UBR5, PSMA3, UBC, UCHL5, PSME3, ADAM19, RAD23B, DERL1, ATG12, UBA6, ANAPC10, SUMO3, ARIH1, SUMO2, SUMO1, UBE2D3, USP34, RNF14, BUB3, CDC27, PSMC6, PSMD12, PSMC3, PSMD11, PSMD10, PSMC2, CUL4B	683	600	13528	1.749594924353343	0.22832021654621704	0.004171687193188944	0.16088739231761018
UP_SEQ_FEATURE	domain:PCI	7	0.8695652173913043	9.023946698651917E-5	COPS2, PSMD12, PSMD11, COPS3, COPS8, PSMD6, EIF3M	802	19	19113	8.780089250557815	0.17621287127057927	0.04730529706656028	0.1563285160544714
GOTERM_CC_FAT	GO:0031982~vesicle	56	6.956521739130435	9.410610169153007E-5	HSP90AB1, SYT1, LDLR, PDIA6, C14ORF1, CANX, PICALM, SLC2A1, IFNGR1, AP3B1, SEC23A, SCAMP1, ADAM10, RAN, RAB4A, GAL, ANXA2P2, ATP6V1C1, SPAG9, PSEN1, SCYL2, VAMP7, NCK1, DLD, RAB5A, RAB14, DST, CAV2, PRF1, CAV1, YWHAZ, GNAI3, OCRL, CALU, ANXA7, SYPL1, TMED2, KLC1, SLC30A5, GAD1, PCSK5, SEC23IP, MYOF, HSPA8, PHLDA1, BMP4, GGH, RGS19, YWHAE, ANXA2, LAMP1, LAMP2, YIPF5, HSPD1, BMP7, ATP6V0A2	624	670	12782	1.7120933792575583	0.047221486781689026	0.001726108999978937	0.13595670175322594
GOTERM_CC_FAT	GO:0042470~melanosome	15	1.8633540372670807	9.513664184431484E-5	HSP90AB1, YWHAZ, RAN, GGH, PDIA6, YWHAE, CANX, ANXA2, CALU, ANXA2P2, LAMP1, SYPL1, SLC2A1, RAB5A, HSPA8	624	89	12782	3.4523552290406228	0.04772608540184187	0.0016848741809857293	0.1374445879630648
GOTERM_CC_FAT	GO:0048770~pigment granule	15	1.8633540372670807	9.513664184431484E-5	HSP90AB1, YWHAZ, RAN, GGH, PDIA6, YWHAE, CANX, ANXA2, CALU, ANXA2P2, LAMP1, SYPL1, SLC2A1, RAB5A, HSPA8	624	89	12782	3.4523552290406228	0.04772608540184187	0.0016848741809857293	0.1374445879630648
GOTERM_MF_FAT	GO:0019899~enzyme binding	47	5.838509316770186	9.628189733035325E-5	GLRX3, CAV2, EID1, CAV1, PDLIM5, PRKAG2, CBX3, ABI2, CBX1, FOXO3, PRDX3, TCF7L2, POT1, STAU1, RANBP9, SLC2A1, NUDT21, PAFAH1B1, RANBP1, RANBP2, CD24, FOXO3B, TPRKB, CUL1, AP3B1, DLG1, ACTB, UBE2A, ADAM10, RBBP4, LYN, BRAF, ROCK1, STRN3, PRKAB1, YWHAE, STAT3, DOCK4, ANXA2, ANXA2P2, RFC5, MAPK1, SPAG9, YWHAH, CUL4B, HDAC9, AKAP1, KPNA2	641	523	12983	1.8201752161864675	0.08468528642257322	0.006300590623248281	0.15037848124479503
GOTERM_BP_FAT	GO:0044257~cellular protein catabolic process	53	6.583850931677018	1.0190446115080245E-4	IDE, CDC16, FBXO28, PSMD4, RANBP2, PSMD6, CUL1, NFX1, TBL1XR1, UBE2A, ADAM10, SOCS2, USP1, HERC4, ERLIN1, UBE2H, SKP1, UBE2N, WDR48, SENP2, PSMA2, SENP3, PSMA1, PJA1, TRIM33, PSEN1, PSMA5, UBR5, PSMA3, UBC, UCHL5, PSME3, ADAM19, RAD23B, DERL1, ATG12, UBA6, ANAPC10, SUMO3, ARIH1, SUMO2, SUMO1, UBE2D3, USP34, RNF14, BUB3, CDC27, PSMC6, PSMD12, PSMC3, PSMD11, PSMD10, PSMC2, CUL4B	683	603	13528	1.7408904719933762	0.2548064239731753	0.004657552516233121	0.18254741582607314
GOTERM_CC_FAT	GO:0030530~heterogeneous nuclear ribonucleoprotein complex	7	0.8695652173913043	1.0206051983249257E-4	HNRPDL, HNRNPH2, HNRNPF, PTBP1, HNRNPD, HNRNPH1, HNRNPU	624	17	12782	8.434577677224736	0.05110941719320761	0.001747198015255469	0.14744069647836255
GOTERM_BP_FAT	GO:0065003~macromolecular complex assembly	57	7.080745341614906	1.0459948048490439E-4	NCBP1, SYT1, IDE, SNRPD1, SKAP2, RANBP9, PICALM, H2AFV, PRMT5, MYC, SYK, SRPK2, BRAF, PRKAB1, TMEM70, MBNL1, SFRS1, GTF2B, GTF2H1, SPAG9, MED7, TAF12, MED17, NCK1, NUP205, RRM1, VAMP3, TOMM22, SIP1, PARVA, CAV2, NUP98, CAV1, POLR2K, TAF9B, ARPC4, FKBP1A, HPRT1, TUBGCP4, MTMR2, TUBB, PTK2, SET, CSE1L, NPM1, SRR, HSPA4, TAF9, SFRS2IP, GTF3C4, GEMIN4, TCP1, TSR1, SOD2, TMEM48, H3F3B, HSPD1	683	665	13528	1.697720142229659	0.26058052190517333	0.0047059218150559134	0.1873708880259728
INTERPRO	IPR012340:Nucleic acid-binding, OB-fold	11	1.3664596273291925	1.1062400981243968E-4	RPA1, MCM7, SSBP1, EIF2S1, NARS2, EIF5A, DARS2, MCM4, POT1, RPA4, YBX1	753	53	16659	4.591671051642487	0.13987558864701144	0.029686095710789062	0.18150482212835328
UP_SEQ_FEATURE	short sequence motif:Nuclear localization signal	30	3.7267080745341614	1.1262694361241129E-4	NCBP1, MORF4, DEK, FOXO3, PDCD4, TCF7L2, DSTN, LOC440434, MAX, SAFB, NPM1, PSIP1, HNRNPC, OGT, FOXO3B, NET1, NKRF, AIFM1, BRIP1, CDKN1C, SENP2, SENP3, NOLC1, RFC1, DR1, KPNA4, THOC2, KPNA2, PARP2, MATR3, KPNA1	802	325	19113	2.199846537502398	0.21489381231215043	0.04723525193842848	0.1950763321095006
GOTERM_BP_FAT	GO:0006297~nucleotide-excision repair, DNA gap filling	7	0.8695652173913043	1.2317412555823653E-4	RFC5, RPA1, RFC3, RFC4, RFC1, RFC2, PCNA	683	17	13528	8.155714408750324	0.2991787526838392	0.005454338801226699	0.22060929663720863
SP_PIR_KEYWORDS	ATP	24	2.981366459627329	1.420890496072622E-4	ABCE1, ABCF2, ROCK1, LYN, BRAF, MAT2A, RYK, MET, MAP2K4, AK2, DDX5, HNRNPU, CDK2, WARS, MAPK1, RPS6KA3, DDX18, FYN, MAPK9, ABCC1, HSPD1, PGK1, HSPA8, SYK	802	236	19235	2.4390295447821124	0.07069953024880082	0.002441120904188687	0.2053237141415698
KEGG_PATHWAY	hsa03050:Proteasome	12	1.4906832298136645	1.486166443535643E-4	PSMA2, PSMA1, PSMC6, PSMD12, PSMD11, PSMC3, PSMA5, PSMC2, PSMA3, PSMD4, PSME3, PSMD6	330	47	5085	3.9342359767891684	0.02320959082076257	0.0039062132971987573	0.17892022354950576
GOTERM_BP_FAT	GO:0043086~negative regulation of catalytic activity	30	3.7267080745341614	1.5620705864289908E-4	CAV1, GNAI3, PRKAG2, FKBP1A, ANAPC10, CDC16, PRDX3, PDCD4, POT1, PSMD4, PSMD6, BUB3, NF1, HBXIP, CDC27, CDKN1C, PSMA2, PSMA1, PSMC6, PSMD12, PSEN1, PSMA5, PSMD11, PSMC3, PSMC2, PSMD10, PSMA3, UBC, PSME3, DNAJB6	683	277	13528	2.1451337537197857	0.36291282799528135	0.006807763664555155	0.2796942777918976
GOTERM_BP_FAT	GO:0044092~negative regulation of molecular function	34	4.22360248447205	1.7123656952435867E-4	CAV1, GNAI3, PRKAG2, FKBP1A, ANAPC10, CDC16, PRDX3, PDCD4, POT1, SUMO1, PSMD4, PSMD6, BUB3, GTPBP4, NF1, HBXIP, CDC27, PROX1, CDKN1C, PSMA2, PSMA1, PSMC6, PSMD12, PSEN1, PSMA5, PSMD11, PSMC3, PSMD10, PSMC2, PSMA3, UBC, PSME3, DNAJB6, CALM1	683	334	13528	2.016254460332629	0.38996018659664644	0.007349442713599386	0.3065661606614256
GOTERM_BP_FAT	GO:0043933~macromolecular complex subunit organization	59	7.329192546583851	1.7707425927220702E-4	NCBP1, SYT1, IDE, SNRPD1, SKAP2, DSTN, RANBP9, PICALM, H2AFV, PRMT5, MYC, SYK, SRPK2, BRAF, PRKAB1, TMEM70, MBNL1, SFRS1, GTF2B, GTF2H1, SPAG9, MED7, TAF12, MED17, NCK1, NUP205, RRM1, TOMM22, VAMP3, SIP1, PARVA, CAV2, CAV1, NUP98, POLR2K, TAF9B, ABI2, ARPC4, FKBP1A, HPRT1, TUBGCP4, MTMR2, TUBB, PTK2, SET, CSE1L, NPM1, SRR, HSPA4, TAF9, SFRS2IP, GTF3C4, GEMIN4, TCP1, TSR1, SOD2, TMEM48, H3F3B, HSPD1	683	710	13528	1.6459117810818058	0.40015354406434067	0.007487731553964538	0.3170017633744471
GOTERM_BP_FAT	GO:0044093~positive regulation of molecular function	51	6.3354037267080745	1.7897404273674685E-4	PRKAG2, PRDX3, CDC16, MAP3K7, FNTA, PSMD4, PSMD6, MYC, CUL1, SYK, SSBP1, SKP1, BCL2L13, PSMA2, UBE2N, PSMA1, SPAG9, MAP4K5, PSEN1, PSMA5, PSMA3, UBC, RIPK2, PSME3, SMARCA4, CAV1, PTPLAD1, FKBP1A, ANAPC10, POT1, NPM1, PRKAA1, CD24, AGK, MSH6, MSH3, MSH2, MET, NF1, STAT1, CDC27, PSMC6, PSMD12, PSMC3, PSMD11, PSMD10, PSMC2, PRKAR1A, LRP8, HSPD1, CALM1	683	586	13528	1.7237943423662923	0.40343395017195827	0.007458500140905655	0.3203976421717658
GOTERM_BP_FAT	GO:0051095~regulation of helicase activity	5	0.6211180124223602	1.9833410207675725E-4	MSH6, MSH3, SSBP1, MSH2, POT1	683	7	13528	14.147667851913825	0.4358578321249532	0.00814449510368176	0.354997681823066
COG_ONTOLOGY	Posttranslational modification, protein turnover, chaperones	15	1.8633540372670807	2.1468217864691196E-4	COPS2, OSGEP, IDE, OSGEPL1, SKP1, PSMC6, HSPA12A, PSMC3, PSMD11, PSMC2, OGT, RCHY1, DNAJB1, PSMD6, DNAJA2	92	104	1950	3.057065217391304	0.004284898039044749	0.004284898039044749	0.1632769581844884
GOTERM_MF_FAT	GO:0016887~ATPase activity	33	4.099378881987578	2.4745927473559463E-4	XRCC5, ABCF2, IDE, SKIV2L2, DDX18, CHD1L, DDX3X, PEX1, DDX19B, DHX15, PSMD6, HSPA8, MSH6, ABCE1, RBBP4, MSH2, BRIP1, ATAD2, DDX5, ATP6V1D, GTF2H1, RFC5, ATP6V1C1, ATP6V1A, RFC3, PSMC6, RFC4, RFC1, RFC2, PSMC2, ABCC1, HSPD1, SMARCA4	641	334	12983	2.0011723822246306	0.20343234757630801	0.015048503420711956	0.38606877781883764
GOTERM_BP_FAT	GO:0010941~regulation of cell death	65	8.074534161490684	2.4912998559071045E-4	XRCC5, EIF5A, FOXO3, PRDX3, MAP3K7, FNTA, BAG1, ATG5, PIK3CA, NGFRAP1, FOXO3B, FOSL1, MYC, API5, CUL1, NET1, BRAF, ROCK1, SOCS2, AIFM1, GAL, BCL2L13, HBXIP, MAPK1, PSEN1, LYST, UBC, RIPK2, MAPK9, PSME3, BID, YWHAZ, MCL1, TAF9B, PRKDC, BCL2L1, TCF7L2, MSX2, TUBB, SH3GLB1, DDX19B, NPM1, SOS2, PRKRA, TAF9, CD24, PHLDA1, PLAGL2, BMP4, MSH6, MSH2, CREB1, TMBIM6, NF1, STAT1, YWHAE, SOD2, PPIF, BIK, HSPD1, APBB2, PERP, BMP7, PDCD5, PDCD6, DNAJB6	683	815	13528	1.5796782509498872	0.5127990994502803	0.01007675505097072	0.44572550450705517
GOTERM_BP_FAT	GO:0010033~response to organic substance	59	7.329192546583851	2.6859084424686667E-4	HSP90AB1, LDLR, IL6ST, RHOQ, DEK, PRDX3, ACTR3, FNTA, CHRNA5, FOSL1, EIF2B3, MYC, ADAM10, LYN, SOCS2, STRN3, GAL, MAPK1, SQLE, MGEA5, RIPK2, CAV2, PRF1, CAV1, DERL1, MCL1, TAF9B, PRKDC, FKBP1A, BCL2L1, HPRT1, TTC3, MSX2, ACSL1, PRKRA, SRR, DNAJA1, HSPA4, TAF9, PPP3CA, CD24, RNF14, HSPA8, BMP4, MAT2A, MSH2, CREB1, GGH, STAT1, STAT3, GART, FYN, PRKAR1A, DNAJB1, HSPD1, HDAC9, BMP7, UBXN4, DNAJB6	683	721	13528	1.620800783034788	0.539414740377226	0.010709700803589461	0.48046436950904825
GOTERM_BP_FAT	GO:0043085~positive regulation of catalytic activity	46	5.714285714285714	2.7087942534064527E-4	CAV1, PTPLAD1, PRKAG2, ANAPC10, CDC16, POT1, MAP3K7, FNTA, NPM1, PSMD4, PRKAA1, CD24, PSMD6, MYC, AGK, CUL1, SYK, MSH6, MSH3, SSBP1, MSH2, NF1, MET, SKP1, STAT1, BCL2L13, CDC27, UBE2N, PSMA2, SPAG9, PSMA1, MAP4K5, PSMC6, PSMD12, PSEN1, PSMA5, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, PRKAR1A, UBC, LRP8, PSME3, HSPD1	683	520	13528	1.7521342493524046	0.5424476258212225	0.010653311880855387	0.4845488794412489
GOTERM_CC_FAT	GO:0000267~cell fraction	79	9.813664596273291	2.7923396397521436E-4	RAB3GAP2, SGPP1, PDLIM5, IDE, CASK, SYNCRIP, FOXO3, RAB1A, WARS, GSR, SLC16A1, CTTN, PGRMC1, SLC2A1, RC3H2, FOXO3B, FOSL1, LYN, AIFM1, SLC33A1, RAB4A, MAPK1, MGAT2, BLMH, PSEN1, SQLE, UBR5, RAB5A, RAB14, TOMM22, VAMP3, EMP1, PRPS1, DEGS1, BID, CAV2, CAV1, YWHAZ, GNAI3, ATG12, ARFRP1, FKBP1A, ARF6, ABI1, HPRT1, LMAN1, ACP1, ANXA7, ACSL1, TMED2, SH3GLB1, SRR, SLC30A5, PAFAH1B1, PPP3CA, CD24, MOBKL3, ACTB, EBP, RYK, SEC11A, TMBIM6, MET, RGS19, LIN7C, GYG1, CAPN2, VDAC3, PTPN12, SOD2, ANXA2, PPIF, LAMP1, LAMP2, CD55, PYGL, CD59, YWHAQ, ABCC1, SPCS2	624	1083	12782	1.494214196084002	0.13371930946559452	0.004619821447812478	0.40291208468687945
GOTERM_BP_FAT	GO:0051789~response to protein stimulus	16	1.9875776397515528	2.9680316780079496E-4	HSP90AB1, DERL1, LYN, DEK, BCL2L1, TTC3, ACTR3, MSX2, FNTA, DNAJA1, HSPA4, HSPD1, DNAJB1, UBXN4, HSPA8, DNAJB6	683	107	13528	2.9617547652604643	0.5754396365333501	0.011510285594520275	0.5308048302285928
GOTERM_CC_FAT	GO:0000785~chromatin	23	2.857142857142857	3.0154628919922607E-4	MSH6, TCP1, UBE2A, RBBP4, PDS5A, RAN, CREB1, MORF4, POLA1, CBX3, ATR, CBX1, HMGN4, SMC3, ATRX, MSL3, ORC2L, CDYL, MCM7, H2AFV, H3F3B, STAG2, SMARCA4	624	200	12782	2.3556570512820514	0.14360038035544254	0.0048326029173432206	0.4350416862419104
UP_SEQ_FEATURE	domain:RRM 1	14	1.7391304347826086	3.023403201167535E-4	PTBP1, GRSF1, ELAVL1, SYNCRIP, SFRS1, HNRPDL, NONO, HNRNPM, HNRNPH2, HNRNPF, HNRNPD, HNRNPH1, RBM12, MATR3	802	101	19113	3.3033999160514553	0.47770629777609397	0.10260055171334259	0.5228602709263619
UP_SEQ_FEATURE	domain:RRM 2	14	1.7391304347826086	3.023403201167535E-4	PTBP1, GRSF1, ELAVL1, SYNCRIP, SFRS1, HNRPDL, NONO, HNRNPM, HNRNPH2, HNRNPF, HNRNPD, HNRNPH1, RBM12, MATR3	802	101	19113	3.3033999160514553	0.47770629777609397	0.10260055171334259	0.5228602709263619
GOTERM_BP_FAT	GO:0042981~regulation of apoptosis	64	7.950310559006211	3.0293128757761384E-4	XRCC5, EIF5A, FOXO3, PRDX3, MAP3K7, FNTA, BAG1, ATG5, PIK3CA, NGFRAP1, FOXO3B, FOSL1, MYC, API5, CUL1, NET1, BRAF, ROCK1, SOCS2, AIFM1, GAL, BCL2L13, HBXIP, MAPK1, PSEN1, LYST, UBC, RIPK2, MAPK9, PSME3, BID, YWHAZ, MCL1, TAF9B, PRKDC, BCL2L1, TCF7L2, MSX2, TUBB, SH3GLB1, DDX19B, NPM1, SOS2, PRKRA, TAF9, CD24, PLAGL2, PHLDA1, MSH6, MSH2, CREB1, TMBIM6, NF1, STAT1, YWHAE, SOD2, PPIF, BIK, HSPD1, APBB2, PDCD5, PERP, BMP7, PDCD6, DNAJB6	683	804	13528	1.5766555218053218	0.5828845107983456	0.01159086421518607	0.5417363185714286
SP_PIR_KEYWORDS	Chaperone	18	2.236024844720497	3.2451439559345917E-4	HSP90AB1, ABCE1, TCP1, C1GALT1C1, DNAJC10, CCT2, CANX, SEC63, TIMM8A, CCT5, BAG1, NPM1, DNAJA1, HSPD1, DNAJB1, HSPA8, DNAJB6, DNAJA2	802	158	19235	2.7323305659900883	0.15420359458898358	0.005387903990557996	0.46835947110863696
SP_PIR_KEYWORDS	transcription factor	11	1.3664596273291925	3.326865441338168E-4	GABPB1, TAF12, CREB1, CREM, ILF3, TFCP2, SKP1, NFYA, TCF7L2, STAT3, TFDP1	802	65	19235	4.058795319393823	0.1577638312648434	0.005351094694464931	0.48012762541563836
GOTERM_CC_FAT	GO:0000228~nuclear chromosome	20	2.484472049689441	3.408818608954627E-4	XRCC5, MSH6, TCP1, RBBP4, MORF4, POLA1, CBX3, ATR, CBX1, POT1, RPA4, SMC3, RPA1, PRIM1, ATRX, ORC2L, MCM7, ORC3L, ORC5L, H3F3B	624	162	12782	2.5288857233301676	0.16074706570871755	0.00529632314849926	0.4916611546470606
GOTERM_BP_FAT	GO:0010942~positive regulation of cell death	40	4.968944099378882	3.4832062762672907E-4	BID, PRKDC, EIF5A, BCL2L1, FOXO3, MSX2, TUBB, SH3GLB1, DDX19B, SOS2, PRKRA, NGFRAP1, CD24, FOXO3B, FOSL1, MYC, CUL1, NET1, PLAGL2, PHLDA1, BMP4, MSH6, AIFM1, NF1, STAT1, BCL2L13, GAL, YWHAE, MAPK1, PSEN1, LYST, UBC, RIPK2, MAPK9, BIK, HSPD1, APBB2, PDCD5, PERP, BMP7, PDCD6	683	435	13528	1.821308964844079	0.6341121624144025	0.013142198813416273	0.6226676129991615
GOTERM_BP_FAT	GO:0006606~protein import into nucleus	14	1.7391304347826086	3.5120310117106395E-4	NUP98, RAN, MAPK1, CSE1L, CEP57, NUP205, SPTBN1, KPNA4, RANBP2, PPP3CA, TPR, KPNA2, KPNA1, TOB1	683	86	13528	3.224352208110593	0.6371443479309663	0.013079299460339477	0.6278050963405168
KEGG_PATHWAY	hsa03420:Nucleotide excision repair	11	1.3664596273291925	3.8401666276284834E-4	RFC5, RPA1, RAD23B, RFC3, RFC4, RFC1, RFC2, PCNA, CUL4B, RPA4, GTF2H1	330	44	5085	3.8522727272727275	0.058881564251579976	0.008631997905096944	0.461718679279699
GOTERM_BP_FAT	GO:0019941~modification-dependent protein catabolic process	49	6.086956521739131	3.861259744456583E-4	CDC16, FBXO28, PSMD4, RANBP2, PSMD6, CUL1, NFX1, TBL1XR1, UBE2A, SOCS2, USP1, HERC4, ERLIN1, UBE2H, SKP1, WDR48, SENP2, PSMA2, UBE2N, PJA1, SENP3, PSMA1, TRIM33, PSMA5, UBR5, PSMA3, UCHL5, UBC, PSME3, RAD23B, DERL1, ATG12, UBA6, ANAPC10, SUMO3, ARIH1, SUMO2, UBE2D3, SUMO1, USP34, RNF14, BUB3, CDC27, PSMC6, PSMD12, PSMC3, PSMD11, PSMD10, PSMC2, CUL4B	683	574	13528	1.6908188408384817	0.67194524850318	0.014187810782986476	0.6900288268141042
GOTERM_BP_FAT	GO:0043632~modification-dependent macromolecule catabolic process	49	6.086956521739131	3.861259744456583E-4	CDC16, FBXO28, PSMD4, RANBP2, PSMD6, CUL1, NFX1, TBL1XR1, UBE2A, SOCS2, USP1, HERC4, ERLIN1, UBE2H, SKP1, WDR48, SENP2, PSMA2, UBE2N, PJA1, SENP3, PSMA1, TRIM33, PSMA5, UBR5, PSMA3, UCHL5, UBC, PSME3, RAD23B, DERL1, ATG12, UBA6, ANAPC10, SUMO3, ARIH1, SUMO2, UBE2D3, SUMO1, USP34, RNF14, BUB3, CDC27, PSMC6, PSMD12, PSMC3, PSMD11, PSMD10, PSMC2, CUL4B	683	574	13528	1.6908188408384817	0.67194524850318	0.014187810782986476	0.6900288268141042
GOTERM_BP_FAT	GO:0043067~regulation of programmed cell death	64	7.950310559006211	3.8762398151639304E-4	XRCC5, EIF5A, FOXO3, PRDX3, MAP3K7, FNTA, BAG1, ATG5, PIK3CA, NGFRAP1, FOXO3B, FOSL1, MYC, API5, CUL1, NET1, BRAF, ROCK1, SOCS2, AIFM1, GAL, BCL2L13, HBXIP, MAPK1, PSEN1, LYST, UBC, RIPK2, MAPK9, PSME3, BID, YWHAZ, MCL1, TAF9B, PRKDC, BCL2L1, TCF7L2, MSX2, TUBB, SH3GLB1, DDX19B, NPM1, SOS2, PRKRA, TAF9, CD24, PLAGL2, PHLDA1, MSH6, MSH2, CREB1, TMBIM6, NF1, STAT1, YWHAE, SOD2, PPIF, BIK, HSPD1, APBB2, PDCD5, PERP, BMP7, PDCD6, DNAJB6	683	812	13528	1.5611219698663532	0.673360995882204	0.014063459599466088	0.6926970736109594
GOTERM_MF_FAT	GO:0008094~DNA-dependent ATPase activity	11	1.3664596273291925	4.1714548676337186E-4	RFC5, XRCC5, RFC3, RBBP4, RFC4, CHD1L, RFC1, RFC2, BRIP1, SMARCA4, GTF2H1	641	57	12983	3.9087226646960618	0.3184847713662209	0.023679917200514433	0.649994613547833
GOTERM_BP_FAT	GO:0051170~nuclear import	14	1.7391304347826086	4.4171191497838154E-4	NUP98, RAN, MAPK1, CSE1L, CEP57, NUP205, SPTBN1, KPNA4, RANBP2, PPP3CA, TPR, KPNA2, KPNA1, TOB1	683	88	13528	3.151071476108079	0.7205864153227677	0.015811935424720036	0.7889930442963822
GOTERM_BP_FAT	GO:0012501~programmed cell death	51	6.3354037267080745	4.750725694804034E-4	FASTKD3, SGPP1, FOXO3, PDCD4, MRPS30, BAG1, ATG5, NGFRAP1, SEMA3A, FOXO3B, MYC, CUL1, API5, NET1, ROCK1, AIFM1, BCL2L13, ELMO2, PSEN1, UBC, RIPK2, PSME3, BID, PRF1, TNFRSF21, MCL1, GULP1, TAF9B, PRKDC, ARF6, BCL2L1, PEG10, CSE1L, SH3GLB1, SOS2, TCTN3, BCAP29, CD24, PHLDA1, DNM1L, PDCD10, MSH2, TMBIM6, STAT1, YWHAE, NCKAP1, SOD2, BIK, HSPD1, PDCD5, PERP, PDCD6	683	611	13528	1.653262658963416	0.7462447895562183	0.016788163122201327	0.8483430370939127
GOTERM_BP_FAT	GO:0051493~regulation of cytoskeleton organization	18	2.236024844720497	4.828245773905283E-4	CAV2, CAV1, CEP76, RHOQ, ARF6, ARPC5, PROX1, DSTN, NEBL, ARPC1A, ACTR3, ARPC2, NCK1, NPM1, SPTBN1, RANBP1, MAPRE1, DST	683	136	13528	2.6214796313840325	0.7518615022952873	0.01685353654402888	0.8621293809151109
GOTERM_CC_FAT	GO:0031988~membrane-bounded vesicle	47	5.838509316770186	4.8320198307746833E-4	HSP90AB1, CAV2, SYT1, PRF1, YWHAZ, GNAI3, LDLR, PDIA6, C14ORF1, OCRL, CANX, CALU, SYPL1, PICALM, TMED2, SLC2A1, SLC30A5, GAD1, PCSK5, HSPA8, PHLDA1, SEC23A, BMP4, SCAMP1, ADAM10, RAN, RAB4A, GGH, RGS19, GAL, YWHAE, ANXA2, ANXA2P2, SPAG9, LAMP1, LAMP2, SCYL2, VAMP7, NCK1, DLD, RAB14, RAB5A, YIPF5, HSPD1, BMP7, DST, ATP6V0A2	624	568	12782	1.69497675153485	0.2199722976274091	0.007280013855176848	0.6962658955415479
GOTERM_BP_FAT	GO:0006461~protein complex assembly	44	5.46583850931677	5.250807682227479E-4	CAV2, SYT1, NUP98, CAV1, POLR2K, TAF9B, IDE, ARPC4, FKBP1A, HPRT1, SKAP2, MTMR2, TUBGCP4, RANBP9, PTK2, TUBB, PICALM, CSE1L, NPM1, SRR, HSPA4, TAF9, MYC, GTF3C4, SYK, TCP1, BRAF, PRKAB1, TMEM70, GTF2B, SOD2, GTF2H1, SPAG9, MED7, TAF12, TMEM48, MED17, NCK1, NUP205, RRM1, VAMP3, TOMM22, HSPD1, PARVA	683	505	13528	1.725735326094835	0.7803634371421722	0.018096675194643752	0.937246915640233
GOTERM_BP_FAT	GO:0070271~protein complex biogenesis	44	5.46583850931677	5.250807682227479E-4	CAV2, SYT1, NUP98, CAV1, POLR2K, TAF9B, IDE, ARPC4, FKBP1A, HPRT1, SKAP2, MTMR2, TUBGCP4, RANBP9, PTK2, TUBB, PICALM, CSE1L, NPM1, SRR, HSPA4, TAF9, MYC, GTF3C4, SYK, TCP1, BRAF, PRKAB1, TMEM70, GTF2B, SOD2, GTF2H1, SPAG9, MED7, TAF12, TMEM48, MED17, NCK1, NUP205, RRM1, VAMP3, TOMM22, HSPD1, PARVA	683	505	13528	1.725735326094835	0.7803634371421722	0.018096675194643752	0.937246915640233
GOTERM_MF_FAT	GO:0019900~kinase binding	21	2.608695652173913	5.275821621780577E-4	ACTB, GLRX3, CAV2, CAV1, ADAM10, BRAF, PDLIM5, PRKAG2, PRKAB1, ABI2, FOXO3, PRDX3, TCF7L2, STAT3, MAPK1, SPAG9, SLC2A1, CD24, FOXO3B, AKAP1, TPRKB, DLG1	641	179	12983	2.376201640244381	0.38428799592431995	0.028124915914338966	0.8214133820579006
GOTERM_BP_FAT	GO:0043065~positive regulation of apoptosis	39	4.84472049689441	5.448386296896146E-4	BID, PRKDC, EIF5A, BCL2L1, FOXO3, MSX2, TUBB, SH3GLB1, DDX19B, SOS2, PRKRA, NGFRAP1, CD24, FOXO3B, FOSL1, MYC, CUL1, NET1, PLAGL2, PHLDA1, MSH6, AIFM1, NF1, STAT1, BCL2L13, GAL, YWHAE, MAPK1, PSEN1, LYST, UBC, RIPK2, MAPK9, BIK, HSPD1, APBB2, PDCD5, PERP, BMP7, PDCD6	683	430	13528	1.796424801661616	0.792543332871291	0.018549991101277197	0.9723514181286808
GOTERM_BP_FAT	GO:0006091~generation of precursor metabolites and energy	31	3.8509316770186333	5.554277081046459E-4	UQCRC2, ACOX1, CYB5R4, ENOX2, IL6ST, PRKAG2, PHKA1, GAPDH, ETFA, FH, ENO1, GLRX, MSH2, HKDC1, GYG1, DLAT, ATP6V1D, IDH3A, SOD2, ATP6V1C1, ATP6V1A, SLC25A14, NNT, PPP1R2, PYGL, SDHC, NDUFV2, DLD, PGK1, STEAP1, ATP6V0A2	683	313	13528	1.961689408220639	0.7987907154424218	0.018686838433121244	0.9911605794235889
INTERPRO	IPR005225:Small GTP-binding protein	19	2.360248447204969	5.557946873422379E-4	RAP2B, GTPBP4, RAP2C, RAB9A, RAN, RAB4A, ARFRP1, RHOQ, ARF6, DRG2, RAB1A, ARF3, RRAS2, ARF4, RAB22A, RAB5A, RALB, RAB14, RHEB	753	167	16659	2.517045590094711	0.5310235890613024	0.11856187111302274	0.9087896301039122
GOTERM_BP_FAT	GO:0010721~negative regulation of cell development	10	1.2422360248447204	5.702934440912765E-4	BMP4, PTK2, YWHAH, PSEN1, NF1, SEMA3A, CD24, BMP7, TTC3, BMPR1A	683	48	13528	4.126403123474866	0.8072452014602107	0.01896137409683174	1.0175605872699278
PIR_SUPERFAMILY	PIRSF004274:phage T4 DNA polymerase accessory protein 44	4	0.4968944099378882	5.72227947204422E-4	RFC5, RFC3, RFC4, RFC2	394	4	7396	18.77157360406091	0.22972726830274925	0.22972726830274925	0.8102863553125839
GOTERM_BP_FAT	GO:0007005~mitochondrion organization	18	2.236024844720497	5.725054631508287E-4	BID, CAV2, YWHAZ, DNM1L, SSBP1, TIMM17A, TMEM70, PRDX3, BCL2L1, TIMM23, SOD2, TIMM8A, PPIF, SH3GLB1, HSPA4, TOMM22, CD24, MYC	683	138	13528	2.583487172958177	0.8084725059379287	0.018817524013845954	1.0214883359284888
SMART	SM00088:PINT	6	0.7453416149068323	5.882938031178842E-4	COPS2, PSMD12, PSMD11, COPS3, PSMD6, EIF3M	393	17	9079	8.153569824876515	0.132223014699707	0.04617351812484094	0.7571827167003775
GOTERM_BP_FAT	GO:0051052~regulation of DNA metabolic process	16	1.9875776397515528	5.922376655734295E-4	CDC6, MSH6, GTPBP4, MSH3, MSH2, USP1, ATR, CDK2, POT1, UBE2N, PCNA, MGEA5, KPNA2, MYC, KPNA1, RAD17	683	114	13528	2.7798926305514886	0.8190807045156716	0.019240941014654456	1.0565191050484701
GOTERM_BP_FAT	GO:0043488~regulation of mRNA stability	7	0.8695652173913043	5.981529903491926E-4	LOC645139, SERBP1, PAIP1, HNRNPD, ELAVL1, SYNCRIP, HNRNPU, YBX1	683	22	13528	6.302142952216158	0.8221448853467699	0.019215081001443757	1.0670183571713787
GOTERM_BP_FAT	GO:0006457~protein folding	21	2.608695652173913	6.078981755298261E-4	HSP90AB1, TCP1, DNAJC10, PDIA6, FKBP1A, CCT2, LMAN1, CANX, SEC63, PPIF, CCT5, SH3GLB1, PPID, DNAJA1, C19ORF2, DNAJB1, HSPD1, RANBP2, HSPA8, DNAJB6, DNAJA2	683	177	13528	2.3499516093009407	0.8270802383005809	0.01931031587165455	1.0843130265064893
GOTERM_BP_FAT	GO:0043068~positive regulation of programmed cell death	39	4.84472049689441	6.123291204345872E-4	BID, PRKDC, EIF5A, BCL2L1, FOXO3, MSX2, TUBB, SH3GLB1, DDX19B, SOS2, PRKRA, NGFRAP1, CD24, FOXO3B, FOSL1, MYC, CUL1, NET1, PLAGL2, PHLDA1, MSH6, AIFM1, NF1, STAT1, BCL2L13, GAL, YWHAE, MAPK1, PSEN1, LYST, UBC, RIPK2, MAPK9, BIK, HSPD1, APBB2, PDCD5, PERP, BMP7, PDCD6	683	433	13528	1.78397844044918	0.8292787400074803	0.019238068907295514	1.0921756299457241
GOTERM_BP_FAT	GO:0000075~cell cycle checkpoint	14	1.7391304347826086	6.141469361367457E-4	CDC6, MSH2, RINT1, BRIP1, TRRAP, ATR, CCNG2, RAD1, CCNE2, ZWILCH, TPR, RAD17, BUB3, DLG1	683	91	13528	3.047189998873747	0.8301725820753043	0.019086933646568438	1.0954011287657606
GOTERM_BP_FAT	GO:0048255~mRNA stabilization	6	0.7453416149068323	6.312582442498244E-4	LOC645139, PAIP1, HNRNPD, ELAVL1, SYNCRIP, HNRNPU, YBX1	683	15	13528	7.922693997071742	0.8383604708463097	0.01940480939428657	1.1257582525457166
GOTERM_BP_FAT	GO:0043489~RNA stabilization	6	0.7453416149068323	6.312582442498244E-4	LOC645139, PAIP1, HNRNPD, ELAVL1, SYNCRIP, HNRNPU, YBX1	683	15	13528	7.922693997071742	0.8383604708463097	0.01940480939428657	1.1257582525457166
GOTERM_CC_FAT	GO:0005783~endoplasmic reticulum	70	8.695652173913043	6.540580721042324E-4	CYB5R4, TUSC3, RAB9A, SGPP1, DNAJC10, EIF5A, SYNCRIP, PDIA6, ALG6, TPD52, C14ORF1, CANX, RAB1A, SSR1, PGRMC1, ANP32A, PIGC, ASPH, IFNGR1, DLG1, SEC23A, SPTLC1, SPTLC2, AIFM1, SLC33A1, RINT1, CNPY2, ERLIN1, C14ORF147, MAGT1, NPC1, PSEN1, SQLE, NCK1, RRAS2, VAMP7, RAB14, MOSPD2, TMCO1, DEGS1, ERMP1, CNBP, CAV1, DERL1, CNIH, FKBP1A, ABI1, LMAN1, SEC63, STAU1, CALU, ACSL1, SET, BCAP29, PCMT1, SEC23IP, EBP, DNM1L, YIPF6, SEC11A, TMBIM6, PTP4A1, GOSR2, YIPF5, SPCS2, PDCD6, UBXN4, ALG13, RCN2, SEL1L	624	960	12782	1.4936231303418803	0.28558827669885223	0.009562438869902157	0.9413777534899692
SP_PIR_KEYWORDS	ribonucleoprotein	25	3.1055900621118013	6.57418370397094E-4	MRPL42, MRPS15, SNRPD1, SYNCRIP, MRPS30, HNRNPM, MRPL13, HNRNPF, MRPL19, RPL3, HNRNPD, LSM4, MRPL18, MRPL39, HNRNPC, SNRPA1, MRPS28, MRPL9, MRPS7, HNRNPU, SLBP, HNRNPH2, UBC, SRP72, HNRNPH1	802	279	19235	2.1490851723737254	0.28775935159304256	0.010230323768635974	0.94670487859837
GOTERM_CC_FAT	GO:0005759~mitochondrial matrix	24	2.981366459627329	7.180054264116921E-4	MRPL42, ME2, MRPS15, MRPS28, SSBP1, GLUD2, GLUD1, PDK3, MRPL9, DARS2, DLAT, IDH3A, SOD2, PPIF, MCCC2, MRPL13, GLS, NARS2, DLD, MRPL18, MRPL39, HSPD1, ETFA, FH	624	227	12782	2.1657065401558793	0.3087041120263394	0.010202798699082694	1.0329723468319951
GOTERM_CC_FAT	GO:0031980~mitochondrial lumen	24	2.981366459627329	7.180054264116921E-4	MRPL42, ME2, MRPS15, MRPS28, SSBP1, GLUD2, GLUD1, PDK3, MRPL9, DARS2, DLAT, IDH3A, SOD2, PPIF, MCCC2, MRPL13, GLS, NARS2, DLD, MRPL18, MRPL39, HSPD1, ETFA, FH	624	227	12782	2.1657065401558793	0.3087041120263394	0.010202798699082694	1.0329723468319951
GOTERM_BP_FAT	GO:0034622~cellular macromolecular complex assembly	31	3.8509316770186333	7.246684268418608E-4	NCBP1, CAV2, CAV1, NUP98, SNRPD1, ARPC4, FKBP1A, PTK2, TUBB, SET, PICALM, CSE1L, H2AFV, PRMT5, NPM1, HSPA4, SFRS2IP, GEMIN4, SRPK2, TCP1, TSR1, TMEM70, MBNL1, SFRS1, TMEM48, NUP205, NCK1, H3F3B, TOMM22, HSPD1, SIP1	683	318	13528	1.930845235135409	0.8765786575948691	0.022011069944085415	1.2913219513911556
INTERPRO	IPR000717:Proteasome component region PCI	6	0.7453416149068323	7.270210393473112E-4	COPS2, PSMD12, PSMD11, COPS3, PSMD6, EIF3M	753	17	16659	7.808296226857276	0.6286323657895188	0.13195260949937082	1.187198296808889
GOTERM_MF_FAT	GO:0003924~GTPase activity	23	2.857142857142857	7.366338004784623E-4	RAP2B, GTPBP4, DNM1L, GNAI3, RAP2C, RAB9A, RAN, RAB4A, HBS1L, EIF5, ARFRP1, RHOQ, ARF6, RAB1A, TUBB, ARF3, RRAS2, ARF4, RAB22A, RAB5A, RALB, RAB14, RHEB	641	211	12983	2.207813620601696	0.49197058185383347	0.036924150813776535	1.145143595972442
SP_PIR_KEYWORDS	prenylation	17	2.111801242236025	8.142127528048955E-4	RAP2B, RAP2C, RAB9A, RAB4A, PHKA1, RHOQ, RAB1A, PTP4A1, RRAS2, PTP4A2, RAB22A, DNAJA1, RAB5A, RALB, RAB14, RHEB, DNAJA2	802	156	19235	2.6136181980945072	0.34315349142428686	0.012285814671951556	1.171258596560254
GOTERM_BP_FAT	GO:0034504~protein localization in nucleus	14	1.7391304347826086	8.402118511145454E-4	NUP98, RAN, MAPK1, CSE1L, CEP57, NUP205, SPTBN1, KPNA4, RANBP2, PPP3CA, TPR, KPNA2, KPNA1, TOB1	683	94	13528	2.9499392542288403	0.911598882474893	0.02521220781369382	1.4957532849720678
GOTERM_BP_FAT	GO:0006508~proteolysis	77	9.565217391304348	8.841947960363701E-4	UQCRC2, METAP2, ATP6AP2, IDE, CDC16, CD46, FBXO28, PSMD4, RANBP2, PSMD6, CUL1, NFX1, TBL1XR1, UBE2A, ADAM10, SOCS2, USP1, HERC4, ERLIN1, OSGEPL1, SKP1, UBE2H, UBE2N, SENP2, PSMA2, WDR48, PSMA1, SENP3, PJA1, BLMH, PSEN1, TRIM33, PSMA5, UBR5, PSMA3, DLD, UBC, UCHL5, PSME3, YME1L1, ADAM19, RAD23B, ERMP1, DERL1, ATG12, AMZ2, UBA6, ANAPC10, SUMO3, LOC440434, SUMO2, ARIH1, SUMO1, UBE2D3, PEG10, USP34, PCSK5, RNF14, BUB3, CAPN7, TMPRSS2, KLK7, OSGEP, SEC11A, CAPN2, CDC27, XPNPEP1, CD55, PSMC6, PSMD12, PSMC3, PSMD11, PSMC2, PSMD10, LRP8, CUL4B, SPCS2, PLAU	683	1054	13528	1.4469815886492507	0.9221456094574976	0.02624238780438426	1.5734673380504827
GOTERM_BP_FAT	GO:0007006~mitochondrial membrane organization	8	0.9937888198757764	8.942804992000815E-4	PPIF, BID, DNM1L, SH3GLB1, HSPA4, TOMM22, BCL2L1, TIMM8A	683	32	13528	4.951683748169839	0.9243810397693129	0.026267889693258883	1.591279740236351
UP_SEQ_FEATURE	compositionally biased region:Asp/Glu-rich (highly acidic)	7	0.8695652173913043	9.076255638110908E-4	SET, EIF5, NPM1, ANP32A, DEK, APLP2, SEC63	802	28	19113	5.95791770573566	0.857792069193045	0.24318607067116038	1.5618947393324478
SP_PIR_KEYWORDS	acetylated amino end	13	1.6149068322981366	9.120138512360362E-4	YWHAZ, EIF5A, GYG1, CAPN2, HPRT1, ACP1, ANXA2, DSTN, GSR, PCMT1, GLRX, FH, CALM1	802	100	19235	3.1178927680798	0.3755061980428053	0.013361753509172236	1.3110847721003793
GOTERM_BP_FAT	GO:0043487~regulation of RNA stability	7	0.8695652173913043	9.898912848898024E-4	LOC645139, SERBP1, PAIP1, HNRNPD, ELAVL1, SYNCRIP, HNRNPU, YBX1	683	24	13528	5.776964372864812	0.9426304242690782	0.028744511235487935	1.7599872190192545
GOTERM_BP_FAT	GO:0002768~immune response-regulating cell surface receptor signaling pathway	9	1.1180124223602486	0.0010292171254329876	MAP3K7, UBE2N, MAPK1, PSEN1, LYN, FYN, RIPK2, CD24, SYK	683	42	13528	4.244300355574148	0.948791524628956	0.029572603086070015	1.8292992940376118
UP_SEQ_FEATURE	domain:RRM 3	9	1.1180124223602486	0.0010346650804150892	HNRNPM, HNRNPH2, HNRNPF, PTBP1, GRSF1, ELAVL1, SYNCRIP, HNRNPH1, RBM12	802	50	19113	4.289700748129675	0.8917823863151043	0.24266636705885536	1.778668739796041
GOTERM_BP_FAT	GO:0006915~apoptosis	49	6.086956521739131	0.0010706707145022088	FASTKD3, SGPP1, FOXO3, PDCD4, MRPS30, ATG5, BAG1, NGFRAP1, SEMA3A, FOXO3B, MYC, CUL1, API5, NET1, ROCK1, AIFM1, BCL2L13, ELMO2, PSEN1, UBC, RIPK2, PSME3, BID, PRF1, TNFRSF21, MCL1, GULP1, ARF6, BCL2L1, PEG10, CSE1L, SH3GLB1, SOS2, TCTN3, BCAP29, CD24, PHLDA1, PDCD10, DNM1L, MSH2, TMBIM6, STAT1, YWHAE, NCKAP1, SOD2, BIK, HSPD1, PDCD5, PERP, PDCD6	683	602	13528	1.6121761040552964	0.9545712914215826	0.030443094461107933	1.9023115498164933
GOTERM_BP_FAT	GO:0050851~antigen receptor-mediated signaling pathway	8	0.9937888198757764	0.001086378156299	MAP3K7, UBE2N, MAPK1, PSEN1, LYN, FYN, RIPK2, SYK	683	33	13528	4.801632725498026	0.9565867961241361	0.030581937651490643	1.929963688566172
GOTERM_MF_FAT	GO:0032135~DNA insertion or deletion binding	4	0.4968944099378882	0.0011064834910933035	MSH6, MSH3, MSH2, PCNA	641	5	12983	16.203432137285493	0.638473998081429	0.05214002194654943	1.715458589400487
GOTERM_BP_FAT	GO:0034621~cellular macromolecular complex subunit organization	33	4.099378881987578	0.0011561100608965505	NCBP1, CAV2, NUP98, CAV1, SNRPD1, ABI2, ARPC4, FKBP1A, DSTN, PTK2, TUBB, SET, PICALM, CSE1L, H2AFV, PRMT5, NPM1, HSPA4, SFRS2IP, GEMIN4, SRPK2, TCP1, TSR1, TMEM70, MBNL1, SFRS1, TMEM48, NUP205, NCK1, H3F3B, TOMM22, HSPD1, SIP1	683	357	13528	1.830874663188848	0.9645085630266845	0.032200206009288745	2.0526342602341763
GOTERM_CC_FAT	GO:0031410~cytoplasmic vesicle	50	6.211180124223603	0.0011721942774912664	HSP90AB1, SYT1, LDLR, PDIA6, C14ORF1, CANX, PICALM, SLC2A1, AP3B1, SEC23A, SCAMP1, ADAM10, RAN, RAB4A, GAL, ANXA2P2, ATP6V1C1, SPAG9, PSEN1, SCYL2, VAMP7, DLD, RAB14, RAB5A, DST, PRF1, CAV2, CAV1, YWHAZ, GNAI3, OCRL, CALU, SYPL1, TMED2, KLC1, SLC30A5, PCSK5, SEC23IP, MYOF, HSPA8, PHLDA1, GGH, RGS19, YWHAE, ANXA2, LAMP1, LAMP2, YIPF5, HSPD1, ATP6V0A2	624	642	12782	1.5953251058391247	0.4527564139418525	0.016161525807388055	1.6812620298673253
GOTERM_BP_FAT	GO:0006271~DNA strand elongation during DNA replication	4	0.4968944099378882	0.0011817976121618733	RFC3, RFC4, POLA1, FEN1	683	5	13528	15.845387994143485	0.9670473915583113	0.03258998165167981	2.0977866118614408
GOTERM_BP_FAT	GO:0008219~cell death	56	6.956521739130435	0.0012633370304155715	FASTKD3, SGPP1, FOXO3, PDCD4, MRPS30, BAG1, ATG5, NGFRAP1, SEMA3A, FOXO3B, MYC, API5, CUL1, NET1, ROCK1, AIFM1, SLC33A1, BCL2L13, ELMO2, PSEN1, UBC, MGEA5, RIPK2, PSME3, BID, FUS, PRF1, TNFRSF21, MCL1, GULP1, TAF9B, PRKDC, ARF6, BCL2L1, HPRT1, PEG10, CSE1L, SH3GLB1, SOS2, TCTN3, BCAP29, CD24, PHLDA1, DNM1L, PDCD10, MSH2, TMBIM6, STAT1, YWHAE, SOD2, NCKAP1, TDP1, BIK, HSPD1, PDCD5, PERP, PDCD6	683	719	13528	1.5426664250209234	0.9739645359599115	0.03447160319704501	2.240982536391478
GOTERM_MF_FAT	GO:0048037~cofactor binding	25	3.1055900621118013	0.0013101128003647636	ACOX1, ME2, GLUD1, UXS1, GSR, AGPS, SRR, GCSH, GAPDH, GAD1, ETFA, SPTLC1, SPTLC2, AIFM1, DLAT, IDH3A, MTRR, NNT, SQLE, PYGL, DLD, NDUFV2, DUS4L, PSAT1, STEAP1	641	249	12983	2.033563270241653	0.700242971300595	0.05846066420801421	2.0281426334457286
GOTERM_CC_FAT	GO:0005667~transcription factor complex	22	2.732919254658385	0.001419573504999927	SUB1, CREB1, HOXA11, CREM, TAF9B, PRKDC, NFYB, TRRAP, NFYA, GTF2B, TCF7L2, CDK2, GTF2H1, MED7, NPAS2, TAF12, MED17, TAF9, HDAC9, GTF3C4, TFDP1, GTF3C3	624	210	12782	2.145940170940171	0.5181773485956491	0.019031805516642852	2.0326955198423313
GOTERM_BP_FAT	GO:0016265~death	56	6.956521739130435	0.001448139934971126	FASTKD3, SGPP1, FOXO3, PDCD4, MRPS30, BAG1, ATG5, NGFRAP1, SEMA3A, FOXO3B, MYC, API5, CUL1, NET1, ROCK1, AIFM1, SLC33A1, BCL2L13, ELMO2, PSEN1, UBC, MGEA5, RIPK2, PSME3, BID, FUS, PRF1, TNFRSF21, MCL1, GULP1, TAF9B, PRKDC, ARF6, BCL2L1, HPRT1, PEG10, CSE1L, SH3GLB1, SOS2, TCTN3, BCAP29, CD24, PHLDA1, DNM1L, PDCD10, MSH2, TMBIM6, STAT1, YWHAE, SOD2, NCKAP1, TDP1, BIK, HSPD1, PDCD5, PERP, PDCD6	683	724	13528	1.5320126513674641	0.9847375681643377	0.039049142951249394	2.564793547760913
GOTERM_BP_FAT	GO:0006417~regulation of translation	17	2.111801242236025	0.0014606205684268025	NCBP1, MAGOH, PAIP1, EIF5, EIF5A, ANKHD1, SELT, EIF4B, LOC645139, MAPK1, EIF4E, EIF2S1, NCK1, HRSP12, NGDN, EIF1, EIF2B3, GATC	683	137	13528	2.4577700355879495	0.9852782969437767	0.03901505181083764	2.586625522953079
GOTERM_MF_FAT	GO:0051082~unfolded protein binding	15	1.8633540372670807	0.0015438185006021881	HSP90AB1, TCP1, DNAJC10, CCT2, LMAN1, CANX, SEC63, CCT5, NPM1, DNAJA1, C19ORF2, HSPD1, DNAJB1, HSPA8, DNAJA2	641	115	12983	2.6418639354269824	0.7582534683468329	0.06537756348064971	2.385862977167663
GOTERM_BP_FAT	GO:0031334~positive regulation of protein complex assembly	8	0.9937888198757764	0.0015667098203508661	ACTR3, CAV2, SUMO1, CAV1, ARPC2, NCK1, ARF6, CD24	683	35	13528	4.527253712612424	0.9891660461751738	0.04140861152524822	2.772017664012294
GOTERM_BP_FAT	GO:0006289~nucleotide-excision repair	10	1.2422360248447204	0.0015792240285521198	RFC5, RPA1, RAD23B, RFC3, DCLRE1A, RFC4, RFC1, RFC2, PCNA, GTF2H1	683	55	13528	3.6012245441235193	0.9895509384399228	0.04135431224611141	2.793864401157453
GOTERM_BP_FAT	GO:0016447~somatic recombination of immunoglobulin gene segments	6	0.7453416149068323	0.0015877497760881992	MSH6, MSH3, SWAP70, MSH2, PRKDC, HSPD1	683	18	13528	6.602244997559785	0.9898053013992679	0.04119960248358823	2.8087456098729757
GOTERM_BP_FAT	GO:0050768~negative regulation of neurogenesis	9	1.1180124223602486	0.0016454174651339103	BMP4, PTK2, YWHAH, PSEN1, NF1, SEMA3A, CD24, BMP7, BMPR1A	683	45	13528	3.961346998535871	0.9913706480673795	0.042285273955677716	2.909344822208748
KEGG_PATHWAY	hsa04114:Oocyte meiosis	17	2.111801242236025	0.0017115879722221885	YWHAZ, ANAPC10, CDC16, SKP1, YWHAE, CDC27, SMC3, CDK2, CCNE2, MAPK1, RPS6KA3, YWHAH, YWHAQ, PPP2R5E, PPP3CA, CUL1, CALM1	330	110	5085	2.381404958677686	0.23712615121520075	0.03326689492147594	2.042891788062018
SP_PIR_KEYWORDS	disease mutation	91	11.304347826086957	0.0017128791152433986	HCCS, ACOX1, RAB3GAP2, LDLR, PRKAG2, CASK, ALG6, PEX3, MTHFD1, MCCC2, SLC16A1, PEX1, AGPS, CD46, SLC2A1, PIK3CA, GLE1, EIF2B3, IFNGR1, AP3B1, SEC23A, SPTLC1, C1GALT1C1, BRAF, SLC33A1, DARS2, MTRR, NEBL, TIMM8A, MGAT2, MAGT1, NPC1, PSEN1, LYST, RRAS2, DLD, GPR56, GIGYF2, PRPS1, FUS, PRF1, CAV1, ALDH18A1, GLUD1, PHKA1, ITGB4, OCRL, HPRT1, SEC63, MTMR2, MSX2, NPAS2, GPHN, NIPBL, PRKRA, PAFAH1B1, SH3TC2, RUNX1, GAD1, ETFA, FH, ACTB, BMP4, MSH6, EBP, LIPA, MSH2, NF1, MET, BRIP1, AK2, STAT1, SMC3, STAT3, PTPN12, DOCK4, CDKN1C, ATRX, LAMP2, RPS6KA3, CCT5, UPF3B, SRPX2, PYGL, TDP1, PRKAR1A, CUL4B, HSPD1, PSAT1, PGK1, BMPR1A	802	1591	19235	1.3717944297019864	0.5871221321804718	0.02427287630304098	2.4491727265785412
SP_PIR_KEYWORDS	GTP binding	10	1.2422360248447204	0.001766944023397887	DNM1L, GNAI3, RAB9A, RAB4A, ARF3, RRAS2, ARF4, RAB5A, RHEB, RAB1A	802	67	19235	3.5796702274165333	0.5985007307736818	0.024361842694376912	2.5255609670202905
SP_PIR_KEYWORDS	cell cycle	34	4.22360248447205	0.001799239558707178	EID1, ANAPC10, CDC16, WTAP, CCNG2, CCNE2, MCM7, NIPBL, PAFAH1B1, TLK2, ZWILCH, STAG2, BUB3, TFDP1, CREBL2, CSNK1A1, CDC6, RBBP4, CGRRF1, PDS5A, RAN, RINT1, CDC5L, SMC3, CDK2, CDKN1C, MAPK1, DCLRE1A, CHMP1B, PTP4A1, PSME3, MAPRE1, MCTS1, RAD17	802	461	19235	1.7688695830921615	0.6051478268552091	0.024157213532143507	2.5711647195423404
GOTERM_BP_FAT	GO:0002764~immune response-regulating signal transduction	10	1.2422360248447204	0.0017992424053775882	MAP3K7, UBE2N, MAPK1, PSEN1, LYN, FYN, RIPK2, HSPD1, CD24, SYK	683	56	13528	3.5369169629784563	0.9944684686118629	0.045743177358617104	3.1772062133008316
GOTERM_BP_FAT	GO:0006006~glucose metabolic process	18	2.236024844720497	0.0018231012626204438	GPD2, IL6ST, CREM, HKDC1, PDK3, PRKAG2, PHKA1, DLAT, GYG1, PPP1R2, PYGL, PIK3CA, PRKAA1, PGK1, GAPDH, MYC, UGP2, ENO1	683	153	13528	2.330204116785807	0.9948371791763387	0.04593195807061001	3.218690015225434
UP_SEQ_FEATURE	cross-link:Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)	19	2.360248447204969	0.0018326337567346428	RBBP4, MCL1, RAN, TMBIM6, SYNCRIP, YBX1, PSMA1, TUBB, SET, PEX1, H2AFV, PKP4, UBC, PCNA, DST, BUB3, CUL1, CALM1, C21ORF59	802	199	19113	2.2753856564618604	0.9805539011330459	0.3545385985387828	3.130030652045346
SP_PIR_KEYWORDS	kinase	46	5.714285714285714	0.001862876134802388	ALDH18A1, PRPF4B, NUAK1, MAPKAPK5, PRKDC, CASK, ZMYND8, MAP3K7, GALK2, PTK2, PIK3CA, ETNK1, TAF9, PRKAA1, TLK2, STK38L, AGK, SYK, CSNK1A1, SRPK2, LYN, ROCK1, BRAF, RYK, PDK3, HKDC1, MAP2K4, MET, AK2, ATR, CDK2, MAPK1, SPAG9, RPS6KA3, MAP4K5, RIOK3, FYN, ADK, PRKAR1A, MAPK9, RIPK2, PGK1, PLAU, CALM1, BMPR1A, PRPS1	802	688	19235	1.6035673896653715	0.6179258343807953	0.024368446219541595	2.6609662878341434
GOTERM_MF_FAT	GO:0043531~ADP binding	6	0.7453416149068323	0.0018704980602572052	MSH6, GLUD2, MSH2, GLUD1, PRKAG2, PRPS1	641	19	12983	6.39609163313901	0.8210407954333954	0.07522884587627454	2.8838447825699554
GOTERM_MF_FAT	GO:0003712~transcription cofactor activity	32	3.9751552795031055	0.0020537465326549006	ENY2, EID1, COPS2, CREM, TAF9B, TRRAP, MED21, RBM9, MAX, PIR, NPM1, TAF9, RNF14, TFDP1, ENO1, TBL1XR1, SUB1, RAN, CREB1, DDX5, PROX1, SFRS2, MED6, MED7, TAF12, YAF2, PSMC3, MED17, DR1, C19ORF2, HDAC9, TOB1	641	363	12983	1.7855021638882085	0.8488275188352373	0.078861569382772	3.1621419017393904
UP_SEQ_FEATURE	short sequence motif:Effector region	12	1.4906832298136645	0.0020682930435175217	RAP2B, RAP2C, RAB9A, RAB4A, RRAS2, RAB22A, RALB, RAB5A, RAB14, RHEB, RHOQ, RAB1A	802	95	19113	3.0103163144769653	0.9882897903536527	0.35900230616826445	3.525756857259943
GOTERM_BP_FAT	GO:0044087~regulation of cellular component biogenesis	17	2.111801242236025	0.00212402961483095	CAV2, CAV1, RHOQ, ARF6, ARPC5, PROX1, ARPC1A, ACTR3, SUMO1, PTK2, ARPC2, NCK1, UBC, SPTBN1, PRKAA1, CD24, MAPRE1	683	142	13528	2.371228837151754	0.9978374534613837	0.05285684806718194	3.7404806128430224
GOTERM_MF_FAT	GO:0032405~MutLalpha complex binding	4	0.4968944099378882	0.002131922011757867	MSH6, MSH2, PCNA, ATR	641	6	12983	13.502860114404577	0.8593284827502004	0.07847188331811483	3.2806387035064555
UP_SEQ_FEATURE	domain:Leucine-zipper	13	1.6149068322981366	0.00220718756591396	XRCC5, CREM, CREB1, PRKDC, TSN, BATF, MAX, BIK, FOSL1, MYC, GEMIN4, API5, CREBL2	802	110	19113	2.816470188165949	0.9913160499968274	0.3504528748658182	3.75827871317842
UP_SEQ_FEATURE	site:Interaction with phosphoserine on interacting protein	4	0.4968944099378882	0.002261109418547103	YWHAZ, YWHAH, YWHAQ, YWHAE	802	7	19113	13.61809761311008	0.9922678032484731	0.33315447458182446	3.848406330868781
GOTERM_BP_FAT	GO:0022616~DNA strand elongation	4	0.4968944099378882	0.0022750558810784717	RFC3, RFC4, POLA1, FEN1	683	6	13528	13.204489995119571	0.9986028088985272	0.05602958276168757	4.001348363805146
GOTERM_BP_FAT	GO:0022618~ribonucleoprotein complex assembly	11	1.3664596273291925	0.0022816660386396847	SRPK2, NCBP1, TSR1, PRMT5, NPM1, SNRPD1, SFRS2IP, MBNL1, SIP1, SFRS1, GEMIN4	683	69	13528	3.1575954336155494	0.9986292700789728	0.055713176751924776	4.012750830740163
SP_PIR_KEYWORDS	er-golgi transport	11	1.3664596273291925	0.0023107920788771373	SEC23A, CNIH, TMED2, ARF3, ARF4, RINT1, BCAP29, ARF6, YIPF5, LMAN1, RAB1A	802	83	19235	3.178574647718054	0.6969169736934473	0.029402786014829152	3.2908721803087237
GOTERM_MF_FAT	GO:0019901~protein kinase binding	17	2.111801242236025	0.0024133088494393534	ACTB, GLRX3, ADAM10, BRAF, PDLIM5, PRKAG2, PRKAB1, FOXO3, PRDX3, TCF7L2, STAT3, MAPK1, SPAG9, CD24, FOXO3B, AKAP1, TPRKB, DLG1	641	147	12983	2.342332876988549	0.8914464089725993	0.08499015303755664	3.706036636780996
UP_SEQ_FEATURE	repeat:TPR 4	12	1.4906832298136645	0.0024436551940354764	RPAP3, TTC26, KLC1, STIP1, SRP72, CDC16, ASPH, OGT, SH3TC2, CDC27, TTC3, GTF3C3	802	97	19113	2.9482479368588836	0.9947807165781846	0.33253022211506067	4.152932228280893
SMART	SM00101:14_3_3	4	0.4968944099378882	0.0024549960265769616	YWHAZ, YWHAH, YWHAQ, YWHAE	393	7	9079	13.201017811704837	0.4469912680244408	0.137651132785379	3.12490485176401
UP_SEQ_FEATURE	compositionally biased region:Poly-Lys	19	2.360248447204969	0.0025392752839747176	CDV3, METAP2, SWAP70, PTPLAD1, POLA1, WBP11, ILF3, ZMYND8, TTC3, RPAP3, ATRX, PAPOLA, DDX18, CEP57, NAV2, PKP4, SRP72, ASPH, SMARCA4	802	205	19113	2.2087890031020008	0.9957519707964955	0.3230059979729263	4.3120843061980825
GOTERM_CC_FAT	GO:0016023~cytoplasmic membrane-bounded vesicle	43	5.341614906832298	0.002590454843404265	HSP90AB1, CAV2, PRF1, SYT1, YWHAZ, GNAI3, LDLR, PDIA6, C14ORF1, OCRL, CANX, CALU, SYPL1, PICALM, TMED2, SLC2A1, SLC30A5, PCSK5, HSPA8, PHLDA1, SEC23A, SCAMP1, ADAM10, RAN, RAB4A, GGH, RGS19, GAL, YWHAE, ANXA2, ANXA2P2, SPAG9, LAMP1, LAMP2, SCYL2, VAMP7, DLD, RAB14, RAB5A, YIPF5, HSPD1, DST, ATP6V0A2	624	550	12782	1.6014743589743592	0.7363733446152056	0.03360745216971883	3.6802727321110007
SP_PIR_KEYWORDS	Apoptosis	29	3.602484472049689	0.002699770042569059	BID, TNFRSF21, MCL1, GULP1, BCL2L1, FOXO3, PDCD4, PEG10, ATG5, BAG1, SH3GLB1, TCTN3, BCAP29, NGFRAP1, FOXO3B, API5, PHLDA1, PDCD10, ROCK1, AIFM1, TMBIM6, BCL2L13, ELMO2, PSEN1, RIPK2, BIK, PSME3, PERP, PDCD5, PDCD6	802	381	19235	1.8255378613832873	0.7521583470920656	0.03345125038225283	3.8348128496584977
GOTERM_MF_FAT	GO:0008134~transcription factor binding	41	5.093167701863354	0.0027264556208004337	ENY2, EID1, COPS2, YWHAZ, CREM, TAF9B, PRKDC, TRRAP, MED21, RBM9, TCF7L2, RAB1A, MAX, PIR, NPM1, TAF9, RUNX1, RNF14, ENO1, TFDP1, TBL1XR1, SUB1, RAN, CREB1, DDX5, PROX1, STAT3, SFRS2, MED6, HHEX, MED7, TAF12, YAF2, PSMC3, MED17, DR1, C19ORF2, APBB2, HDAC9, TOB1, SMARCA4	641	513	12983	1.6187639318438234	0.9186532712128583	0.0919913127667098	4.177389688703492
INTERPRO	IPR000308:14-3-3 protein	4	0.4968944099378882	0.0027972226850930017	YWHAZ, YWHAH, YWHAQ, YWHAE	753	7	16659	12.64200341491178	0.9779657167332838	0.37929196682961075	4.4956673004010295
GOTERM_MF_FAT	GO:0003690~double-stranded DNA binding	13	1.6149068322981366	0.002851138249236284	XRCC5, MSH6, MSH3, MSH2, CREB1, YBX1, HNRPDL, ZNF148, SAFB, TDP1, PCNA, MYC, FEN1	641	97	12983	2.7144924972256623	0.9274833027472992	0.09260997527543247	4.364461958224131
SP_PIR_KEYWORDS	gtp-binding	26	3.229813664596273	0.002877089303584728	RAB9A, GNAI3, GLUD1, ARFRP1, HBS1L, EIF5, RHOQ, ARF6, RAB1A, TUBB, RALB, RAP2B, GTPBP4, RAP2C, DNM1L, RAN, RAB4A, DRG2, NOLC1, RRAS2, ARF3, RAB22A, ARF4, RAB5A, RAB14, RHEB	802	329	19235	1.8953755429056538	0.7738864150376924	0.03477886000229724	4.081827093379664
GOTERM_BP_FAT	GO:0010638~positive regulation of organelle organization	12	1.4906832298136645	0.0029068387098005856	UBE2N, ACTR3, CAV2, CAV1, ARPC2, NCK1, NPM1, RANBP1, ARF6, PROX1, POT1, DSTN	683	83	13528	2.8636243362909912	0.9997754367447962	0.06986492181161441	5.0854075222028
GOTERM_BP_FAT	GO:0002429~immune response-activating cell surface receptor signaling pathway	8	0.9937888198757764	0.0030093655619832117	MAP3K7, UBE2N, MAPK1, PSEN1, LYN, FYN, RIPK2, SYK	683	39	13528	4.06291999849833	0.9998331012977313	0.07164672643992043	5.260236726125022
GOTERM_BP_FAT	GO:0051053~negative regulation of DNA metabolic process	8	0.9937888198757764	0.0030093655619832117	MSH6, CDC6, GTPBP4, MSH3, MSH2, ATR, POT1, RAD17	683	39	13528	4.06291999849833	0.9998331012977313	0.07164672643992043	5.260236726125022
GOTERM_BP_FAT	GO:0007264~small GTPase mediated signal transduction	28	3.4782608695652173	0.0032363105401484586	RAB9A, PTPLAD1, ARFRP1, RHOQ, ARF6, RGL1, RAB1A, SOS2, RALB, RAPGEF2, RAP2B, GDI2, RAP2C, ROCK1, BRAF, RAB4A, NF1, RGS19, MAPK1, RRAS2, ARF3, RAB22A, ARF4, RAB5A, RAB14, YWHAQ, RHEB, BCAR3	683	305	13528	1.8183232124426951	0.9999134803034324	0.07621954135480147	5.646143384057289
GOTERM_BP_FAT	GO:0006917~induction of apoptosis	29	3.602484472049689	0.0032766608027715196	BID, EIF5A, FOXO3, TUBB, SH3GLB1, DDX19B, PRKRA, SOS2, NGFRAP1, CD24, FOXO3B, MYC, CUL1, PLAGL2, PHLDA1, NET1, MSH6, AIFM1, STAT1, BCL2L13, YWHAE, MAPK1, PSEN1, LYST, UBC, MAPK9, BIK, PERP, PDCD5, PDCD6	683	320	13528	1.7949853587115665	0.9999230203749927	0.07651099454834653	5.714601046920054
UP_SEQ_FEATURE	nucleotide phosphate-binding region:GTP	24	2.981366459627329	0.00327701168691828	RAP2B, GTPBP4, DNM1L, GNAI3, RAP2C, RAB9A, RAN, RAB4A, HBS1L, EIF5, ARFRP1, RHOQ, ARF6, DRG2, RAB1A, TUBB, ARF3, RRAS2, ARF4, RAB22A, RAB5A, RALB, RAB14, RHEB	802	295	19113	1.9388477957648254	0.9991330938550484	0.37502189132529606	5.531642542522541
SP_PIR_KEYWORDS	transport	93	11.5527950310559	0.0033692693567904442	ENY2, UQCRC2, NCBP1, ENOX2, RAB9A, LDLR, SLC20A1, CHMP5, TIMM17A, XPO4, PITPNB, SLC7A8, EIF5A, RAB1A, SLC16A1, PEX1, ATP5S, SLC2A1, CHRNA5, MAGOHB, GLE1, RANBP2, TPR, APOO, AP3B1, SEC23A, SCAMP1, SLC33A1, RAN, MAGOH, RAB4A, RINT1, VTI1B, TIMM23, ATP6V1D, TIMM8A, ATP6V1C1, SENP2, ATP6V1A, CHMP1B, NUP205, LYST, VAMP7, RAB5A, RAB14, TOMM22, KPNA4, TMCO3, THOC2, KPNA2, STEAP1, KPNA1, NUP98, SLC38A2, DERL1, RBP1, CNIH, GULP1, SNX2, ARF6, LMAN1, SEC63, NXT2, TMED2, CSE1L, DDX19B, NUP50, SLC25A46, BCAP29, SLC30A5, PAFAH1B1, EXOC5, ETFA, MOBKL3, TNPO3, NMD3, GLRX, LIN7C, AP4S1, NUP155, VDAC3, SLC25A14, TMEM48, UPF3B, SDHC, ARF3, RAB22A, NDUFV2, ARF4, ABCC1, GOSR2, YIPF5, ATP6V0A2	802	1670	19235	1.335624262696552	0.8247388958337549	0.039690352949036445	4.7643661574541145
GOTERM_BP_FAT	GO:0012502~induction of programmed cell death	29	3.602484472049689	0.0033737196934905877	BID, EIF5A, FOXO3, TUBB, SH3GLB1, DDX19B, PRKRA, SOS2, NGFRAP1, CD24, FOXO3B, MYC, CUL1, PLAGL2, PHLDA1, NET1, MSH6, AIFM1, STAT1, BCL2L13, YWHAE, MAPK1, PSEN1, LYST, UBC, MAPK9, BIK, PERP, PDCD5, PDCD6	683	321	13528	1.7893935040115305	0.9999418809039943	0.0780600019784331	5.879077702848868
GOTERM_CC_FAT	GO:0005885~Arp2/3 protein complex	4	0.4968944099378882	0.003480131883792227	ACTR3, ARPC2, ARPC4, ARPC5	624	7	12782	11.705128205128204	0.8333580261999747	0.04380909164500035	4.914875781360106
GOTERM_MF_FAT	GO:0008565~protein transporter activity	12	1.4906832298136645	0.0035463083827579917	CSE1L, MCL1, TIMM17A, RAB4A, SNX2, TOMM22, KPNA4, AP4S1, TIMM23, KPNA2, KPNA1, AP3B1	641	87	12983	2.7936951960837053	0.9617973316528479	0.11006048802205448	5.401235643599023
GOTERM_MF_FAT	GO:0003688~DNA replication origin binding	4	0.4968944099378882	0.003594576478763954	ORC2L, ORC3L, ORC5L, HSPD1	641	7	12983	11.573880098061066	0.9634607129815383	0.10784563973062067	5.472830451667154
GOTERM_MF_FAT	GO:0050662~coenzyme binding	19	2.360248447204969	0.0036154746229419433	ACOX1, ME2, AIFM1, GLUD1, DLAT, UXS1, IDH3A, MTRR, GSR, NNT, AGPS, SQLE, DLD, NDUFV2, GCSH, DUS4L, STEAP1, GAPDH, ETFA	641	181	12983	2.1261409572404997	0.9641582592319792	0.10502074288524532	5.503812388141238
GOTERM_BP_FAT	GO:0006302~double-strand break repair	10	1.2422360248447204	0.0036851416269620746	RPA1, UBE2N, XRCC5, MSH2, TDP1, POLA1, PRKDC, BRIP1, FEN1, SOD2	683	62	13528	3.194634676238606	0.9999764165022937	0.08429182221136089	6.404988143489209
GOTERM_BP_FAT	GO:0008652~cellular amino acid biosynthetic process	9	1.1180124223602486	0.0037281877977380804	MTHFD1, ALDH18A1, MAT2A, GLUD2, GLUD1, SRR, ENOPH1, PSAT1, MTRR	683	51	13528	3.49530617517871	0.999979181255224	0.08456676282001974	6.477463250108794
UP_SEQ_FEATURE	splice variant	350	43.47826086956522	0.003923364712786177	RAB3GAP2, IL6ST, PITPNB, MORF4, SYNCRIP, CDC16, TPD52, WTAP, UXS1, RAB1A, SSR1, MAP3K7, SFRS7, PICALM, CD46, C7ORF49, OGT, TLK2, MRPL39, GLE1, EIF2B3, APOO, SYK, STRN3, HKDC1, PTBP1, RAP1GDS1, VTI1B, SKP1, BCL2L13, SFRS1, TANK, RAD1, SPAG9, RFC1, RFC2, NAV2, MTF2, MED17, SERBP1, MAPK9, YME1L1, SIP1, GIGYF2, MCTS1, FUS, CDV3, AKAP12, ASAP1, UBA6, BCL2L1, OCRL, ACP1, CALU, SYPL1, GORASP2, BZW1L1, TCTN3, RCHY1, ARNTL2, GAD1, SEC23IP, PRPF40A, FH, ZC3H14, GPD2, PAIP1, RTCD1, LGALS8, TFCP2, ATR, VDAC3, GART, NCKAP1, CD55, RPE, C1ORF116, UPF3B, NOLC1, NSMCE4A, AIDA, PARP8, CD58, PKP4, PON2, MAP7, GOSR2, C15ORF44, UTP14A, PARP2, PLAU, COPS2, ENOX2, NUAK1, PION, DNAJC10, PDIA6, CCNE2, MCCC2, CTAGE4, BAG1, FAM115A, KIAA1033, CLDND1, MYC, AP3B1, C1ORF144, EXOSC9, LYN, AIFM1, CNPY2, HERC4, HN1, CD164, RNF170, MTRR, HNRPDL, WDR48, PJA1, TAF12, PRUNE, PSEN1, ADK, NAB1, C19ORF2, MGEA5, TOP3A, MOSPD2, ADAM19, MOSPD1, THOC2, TMCO3, TMCO1, PARVA, BID, ALDH18A1, ATG12, GULP1, CREM, PPFIA1, ABI2, ABI1, POT1, STAU1, NXT2, GIN1, GPHN, NUMA1, ACSL1, SET, KLC1, LINS1, DDX19B, PCMT1, PRKAA1, PPP3CA, USP34, ZWILCH, TPRKB, BCAS4, AGK, BUB3, NBPF14, CSNK1A1, PDS5A, ILF3, ANKHD1, STAT1, PRPF18, CAPRIN1, STAT3, ATRX, PAPOLA, TJP1, FYN, YAF2, SVIL, PTP4A2, ABCC1, LRP8, APBB2, PSAT1, BCAR3, MPZL1, TUSC3, CEP76, HBS1L, EIF5A, CASK, RBM9, TCEAL1, RGL1, PNN, GABPB1, FNTA, ATG5, PSIP1, RC3H2, ENOPH1, RNF146, API5, NET1, SCAMP1, NUDT4, TOR1AIP1, TMEM126B, HNRNPU, LOC645139, PSMA1, ZNF195, TRIM33, RIOK3, VAMP7, LYST, GPR56, PSMA3, CLIP1, RIPK2, AKAP1, DST, RAD17, CAV2, EID1, CAV1, CNBP, SLC38A2, MCL1, MAPKAPK5, PHKA1, TH1L, ITGB4, ARPC4, ARPC5, TRRAP, ZMYND8, TTC3, HNRNPM, PEG10, UBE2D3, PTK2, NIPBL, CSE1L, NPM1, PRKRA, HNRNPD, RNFT1, SLC30A5, SSX2IP, HNRNPC, B3GNT2, RUNX1, SH3TC2, EWSR1, TMEM30A, CSTF2, SMCHD1, RYK, ZMYM6, MET, C21ORF33, AK2, BRIP1, ATAD2, SMEK1, MOBKL1B, IDH3A, DOCK4, MSL3, CDKN1C, LAMP2, SLC25A14, GLS, SPTBN1, YIPF5, WDR1, HDAC9, PDCD6, DNAJB6, C6ORF62, SEL1L, KIAA0802, ACOX1, PRKAG2, ECHDC1, AMMECR1, DPY19L1, ZNF207, FUBP1, ACOT9, WARS, GSR, MAX, RANBP9, MCM7, CAMSAP1, SNTB1, DLG3, PSMD4, PDE8A, NFX1, KIF2A, DLG1, TMEM70, OSGEPL1, MBNL2, MBNL1, C20ORF30, LARP4, UCHL5, PSME3, UGP2, NUP98, ABLIM3, PRKDC, NFYA, TCF7L2, TPM4, APLP2, C3ORF63, ANXA7, CHD1L, CDYL, CEP57, SH3GLB1, PAFAH1B1, SFRS2IP, MYOF, HSPA8, MOBKL3, TNPO3, ENO1, GTF3C3, DCTD, MSH6, KLK7, LIPA, DNM1L, CEP192, CREB1, NF1, GYG1, NUP155, XPNPEP1, ANXA2, RPAP3, TMEM48, ORC3L, NGDN, CUL4B, DUS4L, CRK	802	7458	19113	1.1184077216452033	0.9997848042821232	0.410067800190953	6.588081852271033
GOTERM_BP_FAT	GO:0008637~apoptotic mitochondrial changes	7	0.8695652173913043	0.0040103261488101906	BID, DNM1L, SH3GLB1, BCL2L1, CD24, MYC, SOD2	683	31	13528	4.4724885467340485	0.9999908070241278	0.08997674870507155	6.951177981386303
GOTERM_BP_FAT	GO:0006405~RNA export from nucleus	8	0.9937888198757764	0.0040319094167733695	HHEX, NCBP1, RAN, DDX19B, NPM1, EIF5A, GLE1, THOC2	683	41	13528	3.8647287790593867	0.9999913643506801	0.08974375048111283	6.987323182734839
GOTERM_BP_FAT	GO:0016445~somatic diversification of immunoglobulins	6	0.7453416149068323	0.00412829523149521	MSH6, MSH3, SWAP70, MSH2, PRKDC, HSPD1	683	22	13528	5.401836816185279	0.9999934688056147	0.09109196886472526	7.14857743750329
SP_PIR_KEYWORDS	mitosis	17	2.111801242236025	0.0042028917250523995	ACTB, CSNK1A1, CDC6, PDS5A, RAN, ANAPC10, CDC16, CCNG2, SMC3, CDK2, NUMA1, DCLRE1A, PAFAH1B1, MAPRE1, ZWILCH, BUB3, STAG2	802	183	19235	2.228002398375646	0.8861942611265656	0.04819236212280098	5.910102132698558
GOTERM_BP_FAT	GO:0007346~regulation of mitotic cell cycle	17	2.111801242236025	0.0042129736875216595	CDC6, CAV2, ANAPC10, CDC16, TRRAP, PROX1, CDK2, PRMT5, RANBP1, ZWILCH, APBB2, TPR, MYC, RAD17, BUB3, SMARCA4, DLG1	683	152	13528	2.2152269399707176	0.9999948900771155	0.09217259581364745	7.290027327334325
GOTERM_BP_FAT	GO:0002757~immune response-activating signal transduction	9	1.1180124223602486	0.004215986371926781	MAP3K7, UBE2N, MAPK1, PSEN1, LYN, FYN, RIPK2, HSPD1, SYK	683	52	13528	3.4280887487329657	0.9999949344997064	0.0915435495487571	7.295056071813466
SMART	SM00028:TPR	13	1.6149068322981366	0.004221751406074936	STIP1, CDC16, CDC27, TTC3, RPAP3, KLC1, PPID, OGT, ASPH, RANBP2, SRP72, SH3TC2, GTF3C3	393	116	9079	2.588992717381767	0.6392592946801092	0.1844717117607737	5.317743659995145
GOTERM_CC_FAT	GO:0005626~insoluble fraction	59	7.329192546583851	0.004252469164360728	SGPP1, PDLIM5, CASK, SYNCRIP, FOXO3, RAB1A, SLC16A1, PGRMC1, SLC2A1, RC3H2, FOXO3B, FOSL1, LYN, AIFM1, SLC33A1, RAB4A, MAPK1, MGAT2, PSEN1, SQLE, RAB14, RAB5A, VAMP3, TOMM22, EMP1, DEGS1, BID, CAV2, CAV1, GNAI3, ATG12, ARFRP1, ARF6, ABI1, FKBP1A, LMAN1, ANXA7, ACSL1, TMED2, SH3GLB1, SLC30A5, PAFAH1B1, PPP3CA, CD24, MOBKL3, EBP, RYK, SEC11A, TMBIM6, MET, LIN7C, RGS19, CAPN2, VDAC3, PPIF, LAMP1, LAMP2, CD59, ABCC1, SPCS2	624	839	12782	1.4404701873414627	0.8881313457798279	0.05202307496955727	5.974686093784587
GOTERM_BP_FAT	GO:0022613~ribonucleoprotein complex biogenesis	19	2.360248447204969	0.00431796006534339	SRPK2, NCBP1, GTPBP4, EXOSC9, TSR1, EXOSC2, SNRPD1, WBP11, MBNL1, SFRS1, DIMT1L, NOLC1, PRMT5, NPM1, SFRS2IP, UTP14A, FTSJ1, SIP1, GEMIN4	683	180	13528	2.090710915893932	0.9999962306759312	0.0929587076703573	7.465117783698128
INTERPRO	IPR000426:Proteasome, alpha-subunit, conserved site	4	0.4968944099378882	0.004326003868979674	PSMA2, PSMA1, PSMA5, PSMA3	753	8	16659	11.061752988047807	0.9972736691614852	0.48112316291977675	6.871784228658551
PIR_SUPERFAMILY	PIRSF000868:14-3-3	4	0.4968944099378882	0.004438814084703948	YWHAZ, YWHAH, YWHAQ, YWHAE	394	7	7396	10.726613488034808	0.8684811196368537	0.6373446810494209	6.127520495584249
PIR_SUPERFAMILY	PIRSF000868:14-3-3 protein	4	0.4968944099378882	0.004438814084703948	YWHAZ, YWHAH, YWHAQ, YWHAE	394	7	7396	10.726613488034808	0.8684811196368537	0.6373446810494209	6.127520495584249
SP_PIR_KEYWORDS	ligase	24	2.981366459627329	0.004543246192104663	UBE2A, RTCD1, UBA6, HERC4, CTPS2, ARPC4, DARS2, UBE2H, GART, UBE2N, MTHFD1, WARS, PJA1, MCCC2, MTHFS, UBE2D3, ACSL1, TRIM33, UBR5, NARS2, RCHY1, PAICS, RNF14, NFX1	802	305	19235	1.8872490903887822	0.9045980843176585	0.05087482926312337	6.374188109905543
GOTERM_CC_FAT	GO:0005740~mitochondrial envelope	34	4.22360248447205	0.004544179187516565	UQCRC2, HCCS, BID, ALDH18A1, ABCF2, MCL1, TIMM17A, BCL2L1, ACSL1, SH3GLB1, ATP5S, SLC25A46, AGK, GPD2, DNM1L, LYN, AIFM1, AK2, TMEM70, TIMM23, VDAC3, TIMM8A, SOD2, PPIF, SLC25A14, NNT, PSEN1, FYN, SDHC, NDUFV2, BIK, TOMM22, HSPD1, AKAP1	624	419	12782	1.6621840768618812	0.9037716409918173	0.05421389244180985	6.3721053263387955
SP_PIR_KEYWORDS	transferase	79	9.813664596273291	0.004569355138175335	NAMPT, PRPF4B, NUAK1, CASK, ALG6, MAP3K7, FNTB, PRIM1, FNTA, AGPS, PRMT5, PIK3CA, PIGC, OGT, TLK2, FTSJ1, SYK, SRPK2, SPTLC1, LYN, BRAF, ROCK1, SPTLC2, HKDC1, CDK2, MTRR, MAPK1, MGAT2, MAP4K5, RIOK3, ADK, MGEA5, MAPK9, RIPK2, MTAP, HAS2, UGP2, PRPS1, ALDH18A1, MAPKAPK5, POLA1, PRKDC, HPRT1, DIMT1L, GALK2, PTK2, CDYL, ETNK1, PCMT1, PRKAA1, TAF9, B3GNT2, AGK, STK38L, GTF3C4, B4GALT4, CSNK1A1, MAT2A, RYK, PDK3, MET, MAP2K4, AK2, ACLY, GYG1, DLAT, ATR, GART, PAPOLA, RPS6KA3, PYGL, FYN, PARP8, MBOAT2, PSAT1, PGK1, PARP2, ALG13, BMPR1A	802	1394	19235	1.3591961631072964	0.905880544546747	0.050076388472766964	6.409700486831471
SP_PIR_KEYWORDS	membrane protein	10	1.2422360248447204	0.004615859845358627	TJP1, NNT, IL6ST, RRAS2, CD59, SPTBN1, DST, CAPRIN1, RAB1A, SSR1	802	77	19235	3.114777990089711	0.9081223652549605	0.04952514024775345	6.472923332888259
UP_SEQ_FEATURE	short sequence motif:BH3	5	0.6211180124223602	0.004707083182988776	BID, MCL1, BIK, BCL2L1, BCL2L13	802	17	19113	7.009314947924307	0.9999603208952843	0.44907576867674215	7.854107532212284
GOTERM_CC_FAT	GO:0000790~nuclear chromatin	9	1.1180124223602486	0.004885117173570208	ATRX, MSH6, TCP1, RBBP4, MORF4, CBX3, H3F3B, ATR, CBX1	624	55	12782	3.3519230769230774	0.9193069975243029	0.056856928916319105	6.834609817644466
GOTERM_BP_FAT	GO:0051172~negative regulation of nitrogen compound metabolic process	41	5.093167701863354	0.004901385557373285	EID1, COPS2, CAV1, TH1L, TAF9B, CBX3, RBM9, TCEAL1, PDCD4, POT1, SUMO1, ORC2L, ZNF148, LANCL2, NPM1, ENO1, NFX1, NKRF, MSH6, CDC6, TBL1XR1, GTPBP4, MSH3, MSH2, STRN3, ILF3, SNW1, ATR, PROX1, STAT3, CDKN1C, HHEX, TRIM33, YAF2, DR1, NAB1, YWHAQ, HDAC9, DNAJB6, RAD17, SMARCA4	683	519	13528	1.5646939011557874	0.999999305572754	0.1040976567506613	8.4324476538709
INTERPRO	IPR011990:Tetratricopeptide-like helical	16	1.9875776397515528	0.004988382539168388	C1ORF163, TTC26, STIP1, CDC16, CDC27, TTC3, RPAP3, KLC1, PPID, SRP72, OGT, ASPH, RANBP2, SH3TC2, GTF3C3, SEL1L	753	157	16659	2.254624812850509	0.9988986070282806	0.49394906678770234	7.883953850874448
SP_PIR_KEYWORDS	Flavoprotein	12	1.4906832298136645	0.004990263663648079	GPD2, ACOX1, GSR, CYB5R4, AGPS, AIFM1, SQLE, DLD, DUS4L, STEAP1, MTRR, ETFA	802	107	19235	2.689770899853171	0.9243337010685374	0.052359088236702656	6.98047633093577
GOTERM_BP_FAT	GO:0050852~T cell receptor signaling pathway	6	0.7453416149068323	0.005059737117671272	MAP3K7, UBE2N, MAPK1, PSEN1, FYN, RIPK2	683	23	13528	5.166974345916354	0.9999995613081314	0.10650210174577157	8.693345209663095
UP_SEQ_FEATURE	lipid moiety-binding region:S-farnesyl cysteine	8	0.9937888198757764	0.005134421605094517	PTP4A1, RRAS2, PTP4A2, PHKA1, DNAJA1, RHEB, RHOQ, DNAJA2	802	51	19113	3.73830130555963	0.9999842260070677	0.45897294898129204	8.53760409091725
UP_SEQ_FEATURE	repeat:TPR 3	14	1.7391304347826086	0.005333061269179736	TTC26, PRKDC, STIP1, CDC16, CDC27, TTC3, RPAP3, KLC1, PPID, OGT, ASPH, SRP72, SH3TC2, GTF3C3	802	138	19113	2.4177057356608476	0.9999897278156294	0.4536688828519624	8.85368463338998
INTERPRO	IPR001440:Tetratricopeptide TPR-1	12	1.4906832298136645	0.005402085649368887	RPAP3, KLC1, PPID, STIP1, SRP72, CDC16, OGT, RANBP2, SH3TC2, CDC27, TTC3, GTF3C3	753	100	16659	2.654820717131474	0.9993748918103031	0.48864418501849827	8.510875602502798
GOTERM_BP_FAT	GO:0043254~regulation of protein complex assembly	12	1.4906832298136645	0.005457285459489933	ACTR3, ARPC1A, CAV2, SUMO1, CAV1, ARPC2, NCK1, SPTBN1, ARF6, ARPC5, MAPRE1, CD24	683	90	13528	2.640897999023914	0.9999998615640684	0.1135727042433704	9.345250055276155
SP_PIR_KEYWORDS	alternative splicing	348	43.22981366459627	0.005457735173830342	RAB3GAP2, IL6ST, PITPNB, MORF4, SYNCRIP, CDC16, TPD52, WTAP, UXS1, RAB1A, SSR1, MAP3K7, SFRS7, PICALM, CD46, C7ORF49, OGT, TLK2, MRPL39, GLE1, EIF2B3, APOO, SYK, STRN3, HKDC1, PTBP1, RAP1GDS1, VTI1B, SKP1, BCL2L13, SFRS1, TANK, RAD1, SPAG9, RFC1, RFC2, NAV2, MTF2, MED17, SERBP1, MAPK9, YME1L1, SIP1, GIGYF2, MCTS1, FUS, CDV3, AKAP12, ASAP1, UBA6, BCL2L1, OCRL, ACP1, CALU, SYPL1, GORASP2, BZW1L1, TCTN3, RCHY1, ARNTL2, GAD1, SEC23IP, PRPF40A, ZC3H14, GPD2, PAIP1, RTCD1, LGALS8, TFCP2, DLAT, ATR, VDAC3, GART, NCKAP1, CD55, RPE, C1ORF116, UPF3B, NOLC1, NSMCE4A, AIDA, PARP8, CD58, PKP4, PON2, MAP7, GOSR2, C15ORF44, UTP14A, PARP2, PLAU, COPS2, ENOX2, NUAK1, PION, DNAJC10, PDIA6, CCNE2, MCCC2, CTAGE4, BAG1, FAM115A, KIAA1033, CLDND1, MYC, AP3B1, C1ORF144, EXOSC9, LYN, AIFM1, CNPY2, HERC4, HN1, CD164, RNF170, MTRR, HNRPDL, WDR48, PJA1, PRUNE, PSEN1, ADK, NAB1, C19ORF2, MGEA5, TOP3A, MOSPD2, ADAM19, MOSPD1, THOC2, TMCO3, TMCO1, PARVA, BID, ALDH18A1, ATG12, GULP1, CREM, PPFIA1, ABI2, ABI1, POT1, STAU1, NXT2, GIN1, GPHN, NUMA1, ACSL1, SET, KLC1, LINS1, DDX19B, PCMT1, PRKAA1, PPP3CA, USP34, ZWILCH, TPRKB, BCAS4, AGK, PCSK5, BUB3, NBPF14, CSNK1A1, PDS5A, ILF3, ANKHD1, STAT1, PRPF18, CAPRIN1, STAT3, ATRX, PAPOLA, TJP1, FYN, YAF2, SVIL, PTP4A2, ABCC1, LRP8, APBB2, PSAT1, BCAR3, MPZL1, TUSC3, CEP76, HBS1L, EIF5A, CASK, RBM9, TCEAL1, RGL1, PNN, GABPB1, FNTA, ATG5, PSIP1, RC3H2, ENOPH1, RNF146, API5, NET1, SCAMP1, NUDT4, TOR1AIP1, TMEM126B, HNRNPU, LOC645139, PSMA1, ZNF195, TRIM33, RIOK3, VAMP7, LYST, GPR56, PSMA3, CLIP1, RIPK2, AKAP1, DST, RAD17, CAV2, EID1, CNBP, SLC38A2, MCL1, MAPKAPK5, PHKA1, TH1L, ITGB4, ARPC4, ARPC5, TRRAP, ZMYND8, TTC3, HNRNPM, UBE2D3, PTK2, NIPBL, CSE1L, NPM1, PRKRA, HNRNPD, RNFT1, SLC30A5, SSX2IP, HNRNPC, B3GNT2, RUNX1, SH3TC2, EWSR1, TMEM30A, CSTF2, SMCHD1, RYK, ZMYM6, MET, C21ORF33, AK2, BRIP1, ATAD2, SMEK1, MOBKL1B, IDH3A, DOCK4, MSL3, CDKN1C, LAMP2, SLC25A14, GLS, SPTBN1, YIPF5, WDR1, EMR2, HDAC9, PDCD6, DNAJB6, C6ORF62, SEL1L, KIAA0802, ACOX1, PRKAG2, ECHDC1, AMMECR1, DPY19L1, ZNF207, FUBP1, ACOT9, WARS, MAX, RANBP9, MCM7, PRMT5, CAMSAP1, SNTB1, DLG3, PSMD4, PDE8A, KIF2A, DLG1, NFX1, TMEM70, OSGEPL1, MBNL2, MBNL1, C20ORF30, LARP4, UCHL5, PSME3, UGP2, NUP98, ABLIM3, PRKDC, NFYA, TCF7L2, TPM4, APLP2, C3ORF63, ANXA7, CHD1L, CDYL, CEP57, SH3GLB1, PAFAH1B1, SFRS2IP, MYOF, HSPA8, MOBKL3, TNPO3, GTF3C3, DCTD, MSH6, KLK7, LIPA, DNM1L, CEP192, CREB1, NF1, GYG1, NUP155, XPNPEP1, ANXA2, RPAP3, TMEM48, ORC3L, NGDN, CUL4B, DUS4L, CRK	802	7488	19235	1.114631290363834	0.9406263313604968	0.056001500974164564	7.610595534476827
GOTERM_MF_FAT	GO:0032404~mismatch repair complex binding	4	0.4968944099378882	0.005541769053886631	MSH6, MSH2, PCNA, ATR	641	8	12983	10.127145085803432	0.9939460838132301	0.15188882193284536	8.319119771838013
GOTERM_BP_FAT	GO:0007178~transmembrane receptor protein serine/threonine kinase signaling pathway	13	1.6149068322981366	0.005593348315947229	BMP4, CREB1, FSTL1, FKBP1A, MAP3K7, MSX2, UBE2D3, FNTA, SPTBN1, BMP7, BAMBI, BMPR1A, TOB1	683	103	13528	2.499879173833317	0.9999999067253371	0.11541283427445304	9.567356376831803
SP_PIR_KEYWORDS	nad	17	2.111801242236025	0.00572712421579275	CYB5R4, ME2, ENOX2, GLUD2, GLUD1, UXS1, VDAC3, IDH3A, BLVRA, SCCPDH, NNT, PARP8, DLD, NDUFV2, STEAP1, GAPDH, PARP2	802	189	19235	2.1572721635065775	0.948371990418786	0.05755132619913583	7.971906351714586
INTERPRO	IPR007695:DNA mismatch repair protein MutS-like, N-terminal	3	0.37267080745341613	0.0059220379425739995	MSH6, MSH3, MSH2	753	3	16659	22.123505976095615	0.9996933469018205	0.4904103331370342	9.293124305211297
INTERPRO	IPR013748:Replication factor C	3	0.37267080745341613	0.0059220379425739995	RFC5, RFC4, RFC2	753	3	16659	22.123505976095615	0.9996933469018205	0.4904103331370342	9.293124305211297
INTERPRO	IPR012996:Zinc finger, CHHC-type	3	0.37267080745341613	0.0059220379425739995	HNRNPH2, HNRNPF, HNRNPH1	753	3	16659	22.123505976095615	0.9996933469018205	0.4904103331370342	9.293124305211297
GOTERM_MF_FAT	GO:0008092~cytoskeletal protein binding	39	4.84472049689441	0.005986546553187791	PDLIM5, ABLIM3, ABI2, ABI1, ARPC4, ARPC5, ARFGEF1, TPM4, DSTN, ACTR3, NUMA1, FNTA, ARPC2, LOC100129652, SNTB1, PAFAH1B1, SSX2IP, CDC42EP3, STK38L, DLG1, CAPN2, NEBL, ANXA2P2, ANXA2, CORO1C, ARPC1A, SPAG9, YWHAH, FYN, NCK1, SVIL, CLIP1, SPTBN1, FLII, WDR1, MAPRE1, DST, CALM1, PARVA	641	504	12983	1.5672962632791028	0.9959868154618126	0.15839358855371988	8.957915000696614
GOTERM_BP_FAT	GO:0002562~somatic diversification of immune receptors via germline recombination within a single locus	6	0.7453416149068323	0.006130749178906148	MSH6, MSH3, SWAP70, MSH2, PRKDC, HSPD1	683	24	13528	4.951683748169839	0.9999999804012795	0.12492188027228479	10.439586610790919
GOTERM_BP_FAT	GO:0016444~somatic cell DNA recombination	6	0.7453416149068323	0.006130749178906148	MSH6, MSH3, SWAP70, MSH2, PRKDC, HSPD1	683	24	13528	4.951683748169839	0.9999999804012795	0.12492188027228479	10.439586610790919
GOTERM_CC_FAT	GO:0005768~endosome	27	3.354037267080745	0.006154830713018521	RAB9A, LDLR, CHMP5, ARF6, PRDX3, SCAMP1, RAB4A, CD164, ANXA2P2, ANXA2, LAMP1, LAMP2, NPC1, CHMP1B, SCYL2, FYN, PTP4A1, VAMP7, RAB22A, PTP4A2, RAB5A, RAB14, CLIP1, HSPD1, CRK, STEAP1, ATP6V0A2	624	315	12782	1.7557692307692307	0.9581372462021387	0.0695824270310883	8.538416689584283
SP_PIR_KEYWORDS	viral nucleoprotein	6	0.7453416149068323	0.006392653257005705	HNRNPM, SNRPA1, HNRNPF, SNRPD1, SYNCRIP, HNRNPU	802	29	19235	4.9621635566256765	0.9634545162074489	0.06282591915892599	8.858898427649475
GOTERM_BP_FAT	GO:0045934~negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	40	4.968944099378882	0.006503264799844786	EID1, COPS2, TH1L, TAF9B, CBX3, RBM9, TCEAL1, PDCD4, POT1, SUMO1, ORC2L, ZNF148, LANCL2, NPM1, ENO1, NFX1, NKRF, MSH6, CDC6, TBL1XR1, GTPBP4, MSH3, MSH2, STRN3, ILF3, SNW1, ATR, PROX1, STAT3, CDKN1C, HHEX, TRIM33, YAF2, DR1, NAB1, YWHAQ, HDAC9, DNAJB6, RAD17, SMARCA4	683	512	13528	1.5474011713030746	0.9999999933570926	0.13109394749748915	11.039531133691572
GOTERM_BP_FAT	GO:0006310~DNA recombination	13	1.6149068322981366	0.0065185962797663565	XRCC5, MSH6, MSH3, MSH2, SWAP70, PRKDC, TSN, ATRX, RPA1, UBE2N, NONO, PSIP1, HSPD1	683	105	13528	2.452262427665063	0.9999999936464539	0.13047594435393595	11.064141327359112
INTERPRO	IPR019734:Tetratricopeptide repeat	13	1.6149068322981366	0.006578431413038781	STIP1, CDC16, CDC27, TTC3, RPAP3, KLC1, PPID, OGT, ASPH, RANBP2, SRP72, SH3TC2, GTF3C3	753	117	16659	2.4581673306772904	0.9998752781207786	0.4991728133824096	10.271675206827279
GOTERM_BP_FAT	GO:0051173~positive regulation of nitrogen compound metabolic process	48	5.962732919254658	0.006724181126503679	HSP90AB1, ENY2, NCBP1, RHOQ, CASK, FOXO3, MED21, ZNF148, FOXO3B, MYC, FOSL1, TBL1XR1, RAN, STRN3, PROX1, CDK2, GTF2H1, MED6, UBE2N, MED7, HHEX, MAPK1, MED17, MGEA5, UBC, SMARCA4, CNBP, ABLIM3, PRKDC, NFYB, NFYA, HPRT1, TCF7L2, POT1, NPAS2, TAF9, RUNX1, RNF14, PLAGL2, BMP4, CREB1, ILF3, DDX5, STAT3, SOD2, YWHAH, ILF2, YAF2, BMP7	683	644	13528	1.4762783845475296	0.999999996503577	0.13339584987456288	11.393527060271369
GOTERM_BP_FAT	GO:0051495~positive regulation of cytoskeleton organization	8	0.9937888198757764	0.006840978320730519	ACTR3, CAV2, CAV1, ARPC2, NCK1, ARF6, PROX1, DSTN	683	45	13528	3.5211973320318855	0.9999999975098028	0.13463607524022492	11.58014476735879
GOTERM_BP_FAT	GO:0032271~regulation of protein polymerization	10	1.2422360248447204	0.006854409482865759	ACTR3, ARPC1A, CAV2, CAV1, ARPC2, NCK1, SPTBN1, ARF6, ARPC5, MAPRE1	683	68	13528	2.9127551459822585	0.9999999976051219	0.13397378378024039	11.601581172055631
GOTERM_BP_FAT	GO:0043066~negative regulation of apoptosis	30	3.7267080745341614	0.006939950462108032	XRCC5, YWHAZ, MCL1, TAF9B, BCL2L1, PRDX3, TCF7L2, MSX2, MAP3K7, FNTA, ATG5, BAG1, SH3GLB1, NPM1, PIK3CA, TAF9, MYC, API5, ROCK1, SOCS2, BRAF, MSH2, TMBIM6, HBXIP, SOD2, PSEN1, UBC, RIPK2, HSPD1, APBB2	683	354	13528	1.6785368637863862	0.9999999981322276	0.13462614608116552	11.737991188088692
SP_PIR_KEYWORDS	sh3 domain	18	2.236024844720497	0.0069664009392687454	LYN, ABI2, ASAP1, CASK, ABI1, SKAP2, DOCK4, NEBL, TJP1, CTTN, SH3GLB1, FYN, NCK1, DLG3, SH3TC2, CRK, DST, DLG1	802	210	19235	2.0557534734592093	0.9728734485431499	0.06701862768263622	9.617173556424397
SP_PIR_KEYWORDS	protein degradation	5	0.6211180124223602	0.007014822773619505	PSMA2, PSMD12, PSMD11, PSMA3, UBC	802	19	19235	6.311523822023887	0.9735474795322013	0.06624008244884994	9.680899245012997
GOTERM_MF_FAT	GO:0032142~single guanine insertion binding	3	0.37267080745341613	0.007040719660284298	MSH6, MSH3, MSH2	641	3	12983	20.254290171606865	0.9984864646354639	0.17861790900161045	10.455332465527366
GOTERM_MF_FAT	GO:0032356~oxidized DNA binding	3	0.37267080745341613	0.007040719660284298	MSH6, MSH3, MSH2	641	3	12983	20.254290171606865	0.9984864646354639	0.17861790900161045	10.455332465527366
GOTERM_MF_FAT	GO:0032357~oxidized purine DNA binding	3	0.37267080745341613	0.007040719660284298	MSH6, MSH3, MSH2	641	3	12983	20.254290171606865	0.9984864646354639	0.17861790900161045	10.455332465527366
GOTERM_MF_FAT	GO:0032139~dinucleotide insertion or deletion binding	3	0.37267080745341613	0.007040719660284298	MSH3, MSH2, PCNA	641	3	12983	20.254290171606865	0.9984864646354639	0.17861790900161045	10.455332465527366
SP_PIR_KEYWORDS	tpr repeat	15	1.8633540372670807	0.0070923255897475486	TTC26, PRKDC, STIP1, CDC16, CDC27, TTC3, RPAP3, KLC1, PPID, SRP72, OGT, ASPH, RANBP2, SH3TC2, GTF3C3	802	160	19235	2.2484803615960103	0.9745916996543518	0.0657512802639253	9.782810000948949
GOTERM_BP_FAT	GO:0006458~'de novo' protein folding	5	0.6211180124223602	0.007167902445078594	SH3GLB1, FKBP1A, DNAJB1, HSPD1, HSPA8	683	16	13528	6.189604685212299	0.9999999990370911	0.1378218008663692	12.100530505546303
GOTERM_CC_FAT	GO:0015630~microtubule cytoskeleton	41	5.093167701863354	0.007205459499971146	CEP76, CBX3, ARPC4, CBX1, CDC16, STAU1, FNTB, TUBGCP4, NUMA1, RANBP9, TUBB, FNTA, CEP57, KLC1, LOC100129652, CAMSAP1, NUDT21, NPM1, PAFAH1B1, RANBP1, MYOF, MYC, KIF2A, CDC6, TBL1XR1, TCP1, ROCK1, CEP192, C21ORF33, SMEK1, CDC27, DCTN4, SMC3, LYST, PTP4A1, CLIP1, FLII, MAP7, MAPRE1, DST, CALM1	624	549	12782	1.5297685768997245	0.9756935545501269	0.07928091937877868	9.926260839967782
GOTERM_MF_FAT	GO:0016564~transcription repressor activity	27	3.354037267080745	0.007324813641488901	COPS2, EID1, TAF9B, CBX3, RBM9, TCF7L2, YBX1, ZNF148, ENO1, NKRF, TBL1XR1, STRN3, ILF3, SNW1, PROX1, SFRS2, CDKN1C, HHEX, RFC1, YAF2, PSMC3, DR1, NAB1, C19ORF2, HDAC9, DNAJB6, TOB1	641	316	12983	1.730588084282865	0.9988364484790687	0.18021573721700557	10.854916884862199
GOTERM_BP_FAT	GO:0016310~phosphorylation	57	7.080745341614906	0.007348606197425707	UQCRC2, PRPF4B, NUAK1, CASK, MAP3K7, PIK3CA, TLK2, SYK, SRPK2, ADAM10, LYN, ROCK1, BRAF, ATP6V1D, CDK2, ATP6V1C1, MAPK1, SPAG9, ATP6V1A, MAP4K5, PSEN1, SCYL2, RIOK3, EIF2S1, DLD, RIPK2, MAPK9, UGP2, CAV2, PTPLAD1, MAPKAPK5, ABI2, PRKDC, ABI1, GALK2, PTK2, PRKRA, PRKAA1, STK38L, AGK, CSNK1A1, RYK, MSH2, PDK3, CREB1, MET, MAP2K4, ATR, STAT1, RPS6KA3, FYN, NDUFV2, SPTBN1, BMP7, PGK1, ATP6V0A2, BMPR1A	683	800	13528	1.4112298682284041	0.9999999994305706	0.1401241653631239	12.3869257014794
GOTERM_BP_FAT	GO:0009309~amine biosynthetic process	11	1.3664596273291925	0.007350912346164905	MTHFD1, ALDH18A1, MAT2A, GLUD2, GLUD1, SRR, ETNK1, ENOPH1, PSAT1, AMD1, MTRR	683	81	13528	2.689803517524357	0.9999999994343757	0.13925014542069047	12.390574988302516
GOTERM_BP_FAT	GO:0032273~positive regulation of protein polymerization	6	0.7453416149068323	0.007351531617550186	ACTR3, CAV2, CAV1, ARPC2, NCK1, ARF6	683	25	13528	4.753616398243046	0.9999999994353932	0.13835792906063427	12.391554908848745
GOTERM_BP_FAT	GO:0043570~maintenance of DNA repeat elements	3	0.37267080745341613	0.007358892539730081	MSH6, MSH3, MSH2	683	3	13528	19.806734992679356	0.999999999447348	0.13759459335160873	12.403201867243862
GOTERM_CC_FAT	GO:0048471~perinuclear region of cytoplasm	25	3.1055900621118013	0.007423954539502004	CYB5R4, CAV2, CAV1, TPD52, SET, PRKRA, ANP32A, RC3H2, PAFAH1B1, GAPDH, MOBKL3, SEC23A, GTPBP4, LYN, ANXA2P2, ANXA2, SPAG9, NPC1, SCYL2, SERBP1, ARF3, RAB5A, RAB14, MAP7, DNAJB6	624	288	12782	1.7781227742165244	0.9782935908984127	0.07989186765668455	10.212411810113798
SP_PIR_KEYWORDS	Redox-active center	7	0.8695652173913043	0.007464700214150912	GSR, AIFM1, DLD, PDIA6, PRDX3, SELT, GLRX	802	42	19235	3.9972984206151287	0.9790629187060372	0.06788133920799377	10.27096554044632
GOTERM_BP_FAT	GO:0044271~nitrogen compound biosynthetic process	28	3.4782608695652173	0.007522449680629551	NAMPT, ALDH18A1, GLUD2, GLUD1, PRKAG2, CTPS2, HPRT1, MTHFD1, GPHN, ATP5S, SRR, ETNK1, ENOPH1, AMD1, DCTD, MAT2A, MSH2, ATP6V1D, MTRR, GART, ATP6V1C1, ATP6V1A, ADK, RRM1, PSAT1, PAICS, ATP6V0A2, PRPS1	683	325	13528	1.7064263993692983	0.9999999996565079	0.13954044741192162	12.661616407366516
GOTERM_BP_FAT	GO:0006839~mitochondrial transport	10	1.2422360248447204	0.007540320999450225	PPIF, BID, SLC25A14, YWHAZ, PSEN1, TIMM17A, TOMM22, BCL2L1, TIMM23, TIMM8A	683	69	13528	2.870541303286863	0.9999999996739026	0.1389607937356394	12.689808799614255
GOTERM_CC_FAT	GO:0009925~basal plasma membrane	6	0.7453416149068323	0.007590539219384252	ACTR3, CAV2, CAV1, MET, ITGB4, DST	624	26	12782	4.72707100591716	0.9800877449282274	0.0799507548777737	10.43000987700432
UP_SEQ_FEATURE	domain:SH3	16	1.9875776397515528	0.007668908335887737	LYN, ABI2, ASAP1, CASK, ABI1, SKAP2, NEBL, DOCK4, TJP1, CTTN, SH3GLB1, FYN, DLG3, SH3TC2, DST, DLG1	802	177	19113	2.1542753286275835	0.9999999341775033	0.5625597737099401	12.494151633568261
GOTERM_BP_FAT	GO:0008283~cell proliferation	35	4.3478260869565215	0.0076992267481052375	XRCC5, COPS2, CDV3, MORF4, POLA1, FKBP1A, CDC16, HPRT1, TCF7L2, PDAP1, ANXA7, MCM7, CSE1L, PRMT5, PAFAH1B1, MYC, BUB3, CUL1, DLG1, SYK, TFDP1, BMP4, LIPA, MET, VTI1B, CDC27, HHEX, PSEN1, FYN, UBR5, PCNA, RIPK2, HSPD1, MAPRE1, EMP1	683	436	13528	1.5899901943664618	0.9999999997945767	0.14078933689667605	12.940108453526399
GOTERM_BP_FAT	GO:0043623~cellular protein complex assembly	17	2.111801242236025	0.007747590434915077	CAV2, CAV1, TCP1, NUP98, TMEM70, ARPC4, FKBP1A, TUBB, PTK2, TMEM48, PICALM, CSE1L, NCK1, NUP205, HSPA4, TOMM22, HSPD1	683	162	13528	2.0784845362688213	0.9999999998215321	0.14072502640902163	13.016153703954792
SP_PIR_KEYWORDS	Proto-oncogene	19	2.360248447204969	0.007864887642057724	FUS, BRAF, LYN, MET, DEK, FOXO3, DOCK4, PICALM, SET, FYN, RRAS2, NPM1, TPR, RUNX1, FOXO3B, CRK, BCAS4, MYC, EWSR1, NET1	802	230	19235	1.9812696519570638	0.9829963144788397	0.07017213975979575	10.792839828388667
GOTERM_CC_FAT	GO:0016604~nuclear body	17	2.111801242236025	0.007957530930414427	MAGOH, WBP11, CDC5L, SFRS1, PRPF18, PNN, SFRS2, RPA1, SUMO1, DDX3X, NPM1, NUDT21, TOP3A, SIP1, MYC, GEMIN4, PRPF40A	624	168	12782	2.0727831196581197	0.9835352176222883	0.0819952749490519	10.907655104555957
SP_PIR_KEYWORDS	FAD	12	1.4906832298136645	0.007988582766660915	GPD2, ACOX1, GSR, CYB5R4, AGPS, AIFM1, SQLE, DLD, DUS4L, STEAP1, MTRR, ETFA	802	114	19235	2.524609528809555	0.9840558267047848	0.07003479008722235	10.953574985832537
GOTERM_BP_FAT	GO:0043069~negative regulation of programmed cell death	30	3.7267080745341614	0.00830777900217974	XRCC5, YWHAZ, MCL1, TAF9B, BCL2L1, PRDX3, TCF7L2, MSX2, MAP3K7, FNTA, ATG5, BAG1, SH3GLB1, NPM1, PIK3CA, TAF9, MYC, API5, ROCK1, SOCS2, BRAF, MSH2, TMBIM6, HBXIP, SOD2, PSEN1, UBC, RIPK2, HSPD1, APBB2	683	359	13528	1.6551589130372721	0.9999999999650254	0.1492071307512306	13.892414993230718
GOTERM_BP_FAT	GO:0019318~hexose metabolic process	19	2.360248447204969	0.008357271793191005	GPD2, IL6ST, CREM, HKDC1, PDK3, PRKAG2, PHKA1, GYG1, DLAT, GALK2, PPP1R2, PYGL, PIK3CA, PRKAA1, PGK1, GAPDH, MYC, UGP2, ENO1	683	192	13528	1.9600414836505613	0.999999999969717	0.14910758105461253	13.969430832985886
SP_PIR_KEYWORDS	DNA binding	25	3.1055900621118013	0.008456925786247429	XRCC5, CNBP, CREM, HOXA11, POLA1, PRKDC, NFYB, NFYA, TCF7L2, YBX1, MSX2, MAX, ZNF148, HNRNPD, FOSL1, TFDP1, SSBP1, SUB1, CREB1, GTF2B, STAT3, ZBTB25, HHEX, RFC1, H3F3B	802	340	19235	1.76351400909491	0.987503797202261	0.07277351389028264	11.559721958699443
GOTERM_BP_FAT	GO:0009113~purine base biosynthetic process	4	0.4968944099378882	0.008526374048209709	HPRT1, PAICS, GART, PRPS1	683	9	13528	8.802993330079714	0.9999999999814884	0.15096913401283207	14.232080748749665
INTERPRO	IPR013026:Tetratricopeptide region	13	1.6149068322981366	0.008541169112766008	TTC26, STIP1, CDC16, CDC27, TTC3, RPAP3, KLC1, PPID, OGT, ASPH, RANBP2, SRP72, GTF3C3	753	121	16659	2.3769056007375453	0.9999915642932597	0.5659096761478407	13.138913135283225
GOTERM_MF_FAT	GO:0050660~FAD binding	10	1.2422360248447204	0.008618851082373558	ACOX1, GSR, AGPS, AIFM1, SQLE, DLD, DUS4L, STEAP1, MTRR, ETFA	641	72	12983	2.81309585716762	0.9996491161572153	0.20330813610133014	12.653984810716034
GOTERM_BP_FAT	GO:0005996~monosaccharide metabolic process	21	2.608695652173913	0.008640367344974	GPD2, IL6ST, CREM, HKDC1, PDK3, PRKAG2, PHKA1, GYG1, DLAT, GALK2, PPP1R2, PYGL, MGEA5, PIK3CA, PRKAA1, PGK1, MYC, GAPDH, UGP2, ENO1, PRPS1	683	222	13528	1.8736100668750744	0.9999999999867158	0.1519079843159864	14.408707907268559
GOTERM_BP_FAT	GO:0060548~negative regulation of cell death	30	3.7267080745341614	0.008669618540484212	XRCC5, YWHAZ, MCL1, TAF9B, BCL2L1, PRDX3, TCF7L2, MSX2, MAP3K7, FNTA, ATG5, BAG1, SH3GLB1, NPM1, PIK3CA, TAF9, MYC, API5, ROCK1, SOCS2, BRAF, MSH2, TMBIM6, HBXIP, SOD2, PSEN1, UBC, RIPK2, HSPD1, APBB2	683	360	13528	1.6505612493899464	0.9999999999878003	0.15146658357011034	14.453975830452602
GOTERM_BP_FAT	GO:0009890~negative regulation of biosynthetic process	43	5.341614906832298	0.009319776035888669	EID1, COPS2, CAV1, TAF9B, TH1L, CBX3, RBM9, TCEAL1, PDCD4, POT1, SUMO1, ORC2L, FNTA, ZNF148, LANCL2, PRKAA1, EIF2B3, ENO1, NFX1, NKRF, CDC6, TBL1XR1, GTPBP4, STRN3, ILF3, SNW1, ANKHD1, ATR, PROX1, STAT3, INHBB, CDKN1C, HHEX, TRIM33, YAF2, DR1, NAB1, YWHAQ, MGEA5, HDAC9, DNAJB6, RAD17, SMARCA4	683	573	13528	1.4863692926443497	0.9999999999981632	0.1609407782056015	15.454316237827538
GOTERM_MF_FAT	GO:0051219~phosphoprotein binding	6	0.7453416149068323	0.009376951991703615	CAV2, MAPK1, LYN, PAFAH1B1, CRK, YWHAE	641	27	12983	4.500953371468192	0.9998262817458605	0.21376701001526555	13.692107658089403
GOTERM_MF_FAT	GO:0042802~identical protein binding	46	5.714285714285714	0.01009308801964855	S100A4, CAV2, SYT1, CAV1, IL6ST, GLUD1, IDE, BCL2L1, PRDX3, HPRT1, LMAN1, TPD52, ACP1, APLP2, MTMR2, NONO, GSR, CEP57, SH3GLB1, NPM1, PRKRA, SRR, PCMT1, PAFAH1B1, HNRNPC, RUNX1, BMP4, ADAM10, PDS5A, MSH3, ROCK1, MSH2, ELAVL1, CDK2, INHBB, FYN, PYGL, CLDN1, CLIP1, PON2, ORC5L, PSME3, PAICS, BMPR1A, PRPS1, SMARCA4	641	640	12983	1.4557771060842435	0.9999106254616581	0.22272742183609695	14.66214720043677
KEGG_PATHWAY	hsa03018:RNA degradation	10	1.2422360248447204	0.010125297002579931	PAPOLA, CNOT8, EXOSC9, WDR61, EDC3, EXOSC2, LSM4, SKIV2L2, HSPD1, ENO1	330	57	5085	2.7033492822966507	0.799702441530093	0.1636108194983925	11.54010001819289
GOTERM_BP_FAT	GO:0016192~vesicle-mediated transport	43	5.341614906832298	0.010179584394686499	CAV2, CAV1, YWHAZ, GNAI3, LDLR, CNIH, CHMP5, GULP1, SNX2, ARF6, LMAN1, ARFGEF1, RAB1A, PICALM, TMED2, BCAP29, EXOC5, CD24, HSPA8, RBM12, AP3B1, SEC23A, SCAMP1, LYN, RINT1, LIN7C, VTI1B, AP4S1, ELMO2, CORO1C, NPC1, PSEN1, ARF3, VAMP7, LYST, ARF4, RAB22A, RAB14, RAB5A, VAMP3, GOSR2, YIPF5, LRP8	683	576	13528	1.4786277859118269	0.9999999999998501	0.17346134776988176	16.760274168065603
GOTERM_MF_FAT	GO:0047485~protein N-terminus binding	10	1.2422360248447204	0.01026433825770754	ACOX1, TBL1XR1, PDLIM5, MORF4, YWHAQ, EIF5A, DCTN4, CALM1, SMARCA4, GLRX	641	74	12983	2.737066239406333	0.9999237636427678	0.22082350005486362	14.892596794294821
GOTERM_BP_FAT	GO:0002200~somatic diversification of immune receptors	6	0.7453416149068323	0.010281616006549985	MSH6, MSH3, SWAP70, MSH2, PRKDC, HSPD1	683	27	13528	4.401496665039857	0.9999999999998886	0.17402806518198077	16.91397886896848
GOTERM_BP_FAT	GO:0016044~membrane organization	31	3.8509316770186333	0.010352281469240818	BID, CAV2, CAV1, GNAI3, LDLR, GULP1, SNX2, BCL2L1, PICALM, SH3GLB1, HSPA4, PAFAH1B1, CD24, HSPA8, AP3B1, SCAMP1, SEC23A, DNM1L, VTI1B, ELMO2, TIMM8A, CORO1C, PPIF, NPC1, VAMP7, RAB22A, RAB5A, LRP8, GOSR2, TOMM22, VAMP3	683	381	13528	1.6115716135775855	0.9999999999999094	0.17410630269220573	17.020275167506394
INTERPRO	IPR009072:Histone-fold	8	0.9937888198757764	0.010381658793417934	TAF12, H2AFV, DR1, TAF9B, SOS2, TAF9, H3F3B, NFYB	753	54	16659	3.277556440903054	0.9999993284844376	0.6123226702550402	15.74919732625938
GOTERM_BP_FAT	GO:0031327~negative regulation of cellular biosynthetic process	42	5.217391304347826	0.010644137474468157	EID1, COPS2, CAV1, TAF9B, TH1L, CBX3, RBM9, TCEAL1, PDCD4, POT1, SUMO1, ORC2L, ZNF148, LANCL2, PRKAA1, EIF2B3, ENO1, NFX1, NKRF, CDC6, TBL1XR1, GTPBP4, STRN3, ILF3, SNW1, ANKHD1, ATR, PROX1, STAT3, INHBB, CDKN1C, HHEX, TRIM33, YAF2, DR1, NAB1, YWHAQ, MGEA5, HDAC9, DNAJB6, RAD17, SMARCA4	683	561	13528	1.4828571652273317	0.9999999999999614	0.17754874951941746	17.45793157325194
GOTERM_CC_FAT	GO:0042588~zymogen granule	4	0.4968944099378882	0.010691301506510318	SCAMP1, GNAI3, TMED2, RAB5A	624	10	12782	8.193589743589742	0.9960137971044309	0.10662905368496789	14.391793258098618
INTERPRO	IPR013753:Ras	13	1.6149068322981366	0.010933666425458007	RAP2B, RAP2C, RAB9A, RAN, RAB4A, RHOQ, RAB1A, RRAS2, RAB22A, RALB, RAB14, RAB5A, RHEB	753	125	16659	2.300844621513944	0.9999996859338408	0.6077492149448183	16.517608483749445
GOTERM_BP_FAT	GO:0010558~negative regulation of macromolecule biosynthetic process	41	5.093167701863354	0.011032243444506883	EID1, COPS2, TH1L, TAF9B, CBX3, RBM9, TCEAL1, PDCD4, POT1, SUMO1, ORC2L, FNTA, ZNF148, LANCL2, EIF2B3, ENO1, NFX1, NKRF, CDC6, TBL1XR1, GTPBP4, STRN3, ILF3, SNW1, ANKHD1, ATR, PROX1, STAT3, INHBB, CDKN1C, HHEX, TRIM33, YAF2, DR1, NAB1, YWHAQ, MGEA5, HDAC9, DNAJB6, RAD17, SMARCA4	683	547	13528	1.4845998806213048	0.9999999999999876	0.18238065357318511	18.036545319756115
UP_SEQ_FEATURE	repeat:TPR 2	14	1.7391304347826086	0.011071985861364528	TTC26, PRKDC, STIP1, CDC16, CDC27, TTC3, RPAP3, KLC1, PPID, OGT, ASPH, SRP72, SH3TC2, GTF3C3	802	151	19113	2.209558884246338	0.9999999999589104	0.6798040711093017	17.553466213865487
UP_SEQ_FEATURE	repeat:TPR 1	14	1.7391304347826086	0.011071985861364528	TTC26, PRKDC, STIP1, CDC16, CDC27, TTC3, RPAP3, KLC1, PPID, OGT, ASPH, SRP72, SH3TC2, GTF3C3	802	151	19113	2.209558884246338	0.9999999999589104	0.6798040711093017	17.553466213865487
GOTERM_BP_FAT	GO:0002443~leukocyte mediated immunity	11	1.3664596273291925	0.011081285762601398	MSH6, CD55, YWHAZ, TUBB, LYN, SWAP70, MSH2, LYST, VAMP7, CD46, HSPD1	683	86	13528	2.533419592086894	0.9999999999999892	0.18208298678141188	18.10938765978237
UP_SEQ_FEATURE	domain:RRM	12	1.4906832298136645	0.011362925377630777	FUS, EIF4B, SFRS7, ENOX2, CSTF2, LARP4, SAFB, HNRNPC, RBM9, EWSR1, SFRS3, SFRS2	802	119	19113	2.403193696431191	0.9999999999781604	0.672342389210224	17.972963233980856
GOTERM_MF_FAT	GO:0016667~oxidoreductase activity, acting on sulfur group of donors	7	0.8695652173913043	0.011399622013031904	GLRX3, GSR, ENOX2, AIFM1, DLD, PRDX3, GLRX	641	39	12983	3.6353854154166165	0.999973448465273	0.23674621817432573	16.40566744724996
INTERPRO	IPR007860:DNA mismatch repair protein MutS, connector	3	0.37267080745341613	0.01148990692938758	MSH6, MSH3, MSH2	753	4	16659	16.592629482071715	0.9999998540281614	0.6038148609416756	17.2852509346882
INTERPRO	IPR017998:Chaperone, tailless complex polypeptide 1	4	0.4968944099378882	0.011516418289575062	CCT5, TCP1, CCT2, HSPD1	753	11	16659	8.044911264034768	0.999999859264105	0.583748485523466	17.3216720490748
GOTERM_BP_FAT	GO:0016053~organic acid biosynthetic process	16	1.9875776397515528	0.011624668746953361	ALDH18A1, MAT2A, GLUD2, GLUD1, PRKAG2, PRKAB1, MTRR, MTHFD1, SH3GLB1, SRR, PRKAA1, ENOPH1, PSAT1, UGP2, SYK, DEGS1	683	155	13528	2.0445661927927077	0.9999999999999978	0.1890900214936031	18.912392024091083
GOTERM_BP_FAT	GO:0046394~carboxylic acid biosynthetic process	16	1.9875776397515528	0.011624668746953361	ALDH18A1, MAT2A, GLUD2, GLUD1, PRKAG2, PRKAB1, MTRR, MTHFD1, SH3GLB1, SRR, PRKAA1, ENOPH1, PSAT1, UGP2, SYK, DEGS1	683	155	13528	2.0445661927927077	0.9999999999999978	0.1890900214936031	18.912392024091083
GOTERM_BP_FAT	GO:0006793~phosphorus metabolic process	66	8.198757763975156	0.011806132114145697	UQCRC2, PRPF4B, SLC20A1, NUAK1, CASK, MAP3K7, PIK3CA, TLK2, SYK, SRPK2, ADAM10, LYN, BRAF, ROCK1, ATP6V1D, CDK2, ATP6V1C1, MAPK1, SPAG9, ATP6V1A, MAP4K5, PSEN1, SCYL2, RIOK3, EIF2S1, DLD, RIPK2, MAPK9, UGP2, CAV2, PTPLAD1, MAPKAPK5, ABI2, PRKDC, ABI1, ACP1, GALK2, MTMR2, PTK2, PRKRA, PRKAA1, PPP3CA, STK38L, AGK, CSNK1A1, GPD2, MSH2, RYK, PDK3, CREB1, MET, MAP2K4, ATR, STAT1, PTPN12, PPA1, RPS6KA3, FYN, PTP4A1, PTP4A2, NDUFV2, SPTBN1, BMP7, PGK1, ATP6V0A2, BMPR1A	683	973	13528	1.343519537016277	0.9999999999999987	0.19069180252427698	19.178896084513863
GOTERM_BP_FAT	GO:0006796~phosphate metabolic process	66	8.198757763975156	0.011806132114145697	UQCRC2, PRPF4B, SLC20A1, NUAK1, CASK, MAP3K7, PIK3CA, TLK2, SYK, SRPK2, ADAM10, LYN, BRAF, ROCK1, ATP6V1D, CDK2, ATP6V1C1, MAPK1, SPAG9, ATP6V1A, MAP4K5, PSEN1, SCYL2, RIOK3, EIF2S1, DLD, RIPK2, MAPK9, UGP2, CAV2, PTPLAD1, MAPKAPK5, ABI2, PRKDC, ABI1, ACP1, GALK2, MTMR2, PTK2, PRKRA, PRKAA1, PPP3CA, STK38L, AGK, CSNK1A1, GPD2, MSH2, RYK, PDK3, CREB1, MET, MAP2K4, ATR, STAT1, PTPN12, PPA1, RPS6KA3, FYN, PTP4A1, PTP4A2, NDUFV2, SPTBN1, BMP7, PGK1, ATP6V0A2, BMPR1A	683	973	13528	1.343519537016277	0.9999999999999987	0.19069180252427698	19.178896084513863
GOTERM_CC_FAT	GO:0009898~internal side of plasma membrane	26	3.229813664596273	0.01192110857872869	CAV2, RAB9A, PHKA1, EIF5A, BCL2L1, GPHN, PTK2, LOC100129652, DDX19B, RALB, SNTB1, TPR, SEC23IP, AP3B1, RAP2B, RAP2C, NUP155, NCKAP1, TJP1, RRAS2, SVIL, RAB5A, RAB14, RHEB, SPTBN1, PARVA	624	316	12782	1.6853902953586497	0.9978967377557826	0.11598859407673434	15.917424531031244
GOTERM_BP_FAT	GO:0048285~organelle fission	21	2.608695652173913	0.011927654120729273	CDC6, DNM1L, PDS5A, RAN, ANAPC10, CDC16, CDC27, CCNG2, CDK2, SMC3, NUMA1, TUBB, DCLRE1A, NIPBL, NOLC1, CLIP1, PAFAH1B1, MAPRE1, ZWILCH, BUB3, STAG2	683	229	13528	1.8163381434334782	0.9999999999999991	0.1914032284824767	19.35690535226322
GOTERM_CC_FAT	GO:0042175~nuclear envelope-endoplasmic reticulum network	24	2.981366459627329	0.011953833725309896	SPTLC1, TUSC3, DERL1, RAB9A, SPTLC2, SLC33A1, SEC11A, EIF5A, ALG6, FKBP1A, ERLIN1, LMAN1, SSR1, C14ORF147, MAGT1, PSEN1, SQLE, VAMP7, RAB14, PIGC, GOSR2, SPCS2, ASPH, DLG1	624	284	12782	1.7310400866738895	0.9979322405272497	0.11414478647072535	15.957673708127695
GOTERM_CC_FAT	GO:0005720~nuclear heterochromatin	6	0.7453416149068323	0.012154276506739909	ATRX, TCP1, CBX3, H3F3B, ATR, CBX1	624	29	12782	4.238063660477454	0.9981370132155045	0.1138565450804957	16.20381039903247
GOTERM_CC_FAT	GO:0005876~spindle microtubule	6	0.7453416149068323	0.012154276506739909	TBL1XR1, NUMA1, PAFAH1B1, CDC16, CDC27, CALM1	624	29	12782	4.238063660477454	0.9981370132155045	0.1138565450804957	16.20381039903247
GOTERM_BP_FAT	GO:0042127~regulation of cell proliferation	55	6.832298136645963	0.012226014918589224	NAMPT, CNOT8, IL6ST, IGFBP6, EIF5A, PRDX3, SKAP2, RBM9, SSR1, FNTB, WARS, FNTA, DLG3, ASPH, IL13RA1, FOSL1, MYC, CUL1, SYK, CDC6, GTPBP4, UBE2A, RBBP4, ADAM10, CGRRF1, LYN, GAL, CD164, PROX1, CDK2, MAPK1, HHEX, NCK1, RIPK2, MCTS1, CAV2, CAV1, CNBP, ABI1, BCL2L1, MSX2, RPA1, PRKRA, NPM1, CD24, DNAJA2, BMP4, NF1, STAT1, SOD2, CDKN1C, BMP7, PLAU, TOB1, BMPR1A	683	787	13528	1.3842063844947454	0.9999999999999997	0.194646577427809	19.792384717354107
GOTERM_CC_FAT	GO:0005819~spindle	15	1.8633540372670807	0.012557950229892565	TBL1XR1, CDC6, CBX3, CDC16, CBX1, CDC27, SMC3, TUBGCP4, NUMA1, PTP4A1, NPM1, PAFAH1B1, MAPRE1, MYC, CALM1	624	147	12782	2.0902014652014653	0.9984900192866403	0.11534681529467294	16.697472466623942
SP_PIR_KEYWORDS	transforming protein	6	0.7453416149068323	0.012630289468570388	BRAF, LYN, FYN, RRAS2, RHEB, RAB1A	802	34	19235	4.232433621827783	0.9985823241601306	0.10520892624007094	16.79396532593068
KEGG_PATHWAY	hsa04910:Insulin signaling pathway	17	2.111801242236025	0.012948361165153422	BRAF, SOCS2, PRKAG2, PHKA1, PRKAB1, RHOQ, MAPK1, EIF4E, PYGL, PRKAR1A, SOS2, PIK3CA, MAPK9, RHEB, PRKAA1, CRK, CALM1	330	135	5085	1.9404040404040404	0.8724442386196116	0.186101950048299	14.532395557064426
GOTERM_BP_FAT	GO:0042493~response to drug	20	2.484472049689441	0.013077180501074481	CAV2, CAV1, YWHAZ, MAT2A, LYN, MSH2, CREB1, GGH, GAL, STAT1, STAT3, SOD2, BLMH, ACSL1, ATG5, SRR, ABCC1, SRP72, FOSL1, BCAR3	683	216	13528	1.8339569437666072	1.0	0.20565748096222503	21.02255260695364
SP_PIR_KEYWORDS	chromosomal rearrangement	21	2.608695652173913	0.013165551466665194	FUS, NUP98, CREB1, MET, ABI1, DEK, FOXO3, CDC5L, NONO, PICALM, SET, TRIM33, NPM1, PSIP1, HAS2, TPR, RUNX1, FOXO3B, HDAC9, BCAS4, MYC, EWSR1	802	279	19235	1.805231544793929	0.9989283337185667	0.10772034071138237	17.44402170985959
KEGG_PATHWAY	hsa04722:Neurotrophin signaling pathway	16	1.9875776397515528	0.013299054394048389	YWHAZ, BRAF, FOXO3, YWHAE, MAPK1, RPS6KA3, YWHAH, PSEN1, SOS2, YWHAQ, RIPK2, PIK3CA, MAPK9, NGFRAP1, FOXO3B, CRK, CALM1	330	124	5085	1.9882697947214076	0.8794086889853212	0.17494429007915047	14.897557321761445
GOTERM_BP_FAT	GO:0045454~cell redox homeostasis	9	1.1180124223602486	0.013389878535787984	GLRX3, GSR, AIFM1, DLD, DNAJC10, PDIA6, PRDX3, SELT, GLRX	683	63	13528	2.829533570382765	1.0	0.20892529211472755	21.46999566487333
GOTERM_BP_FAT	GO:0030832~regulation of actin filament length	9	1.1180124223602486	0.013389878535787984	ACTR3, ARPC1A, ARPC2, NCK1, SPTBN1, ARF6, ARPC5, DSTN, NEBL	683	63	13528	2.829533570382765	1.0	0.20892529211472755	21.46999566487333
GOTERM_CC_FAT	GO:0005813~centrosome	20	2.484472049689441	0.013425983993144819	TCP1, ROCK1, CEP192, CEP76, C21ORF33, CDC16, SMEK1, CDC27, DCTN4, TUBGCP4, CEP57, NPM1, NUDT21, FLII, RANBP1, PAFAH1B1, MAPRE1, MYOF, CALM1, KIF2A	624	224	12782	1.828926282051282	0.9990391581230371	0.1207281209058334	17.749856138014685
SMART	SM00337:BCL	5	0.6211180124223602	0.013494968968651206	BID, MCL1, BIK, BCL2L1, BCL2L13	393	22	9079	5.250404811473513	0.9621616344829254	0.420586342263806	16.095237374481396
UP_SEQ_FEATURE	nucleotide phosphate-binding region:FAD	8	0.9937888198757764	0.013520720872617822	GPD2, GSR, CYB5R4, AIFM1, SQLE, DLD, MTRR, ETFA	802	61	19113	3.125465025959691	0.9999999999998	0.7195421744204802	21.02203043630153
GOTERM_MF_FAT	GO:0032137~guanine/thymine mispair binding	3	0.37267080745341613	0.01362197670864244	MSH6, MSH3, MSH2	641	4	12983	15.19071762870515	0.9999966436044689	0.27029582956987286	19.294945055650846
GOTERM_MF_FAT	GO:0032138~single base insertion or deletion binding	3	0.37267080745341613	0.01362197670864244	MSH6, MSH3, MSH2	641	4	12983	15.19071762870515	0.9999966436044689	0.27029582956987286	19.294945055650846
GOTERM_MF_FAT	GO:0032134~mispaired DNA binding	3	0.37267080745341613	0.01362197670864244	MSH6, MSH3, MSH2	641	4	12983	15.19071762870515	0.9999966436044689	0.27029582956987286	19.294945055650846
SP_PIR_KEYWORDS	ubl conjugation pathway	33	4.099378881987578	0.013639082283247724	RAD23B, ATG12, UBA6, ANAPC10, CDC16, SUMO3, ARIH1, SUMO2, SUMO1, UBE2D3, FBXO28, RANBP2, RCHY1, USP34, RNF14, CUL1, NFX1, TBL1XR1, UBE2A, SOCS2, USP1, HERC4, UBE2H, SKP1, CDC27, UBE2N, WDR48, SENP2, PJA1, SENP3, TRIM33, UBR5, UCHL5, CUL4B	802	509	19235	1.5549412323807377	0.9991634311289614	0.10967368832704227	18.01516351657064
GOTERM_CC_FAT	GO:0000792~heterochromatin	7	0.8695652173913043	0.0137361485324331	ATRX, TCP1, CBX3, H3F3B, ATR, CBX1, SMARCA4	624	41	12782	3.4972639149468416	0.9991825495288894	0.12125486140213038	18.122881640832155
GOTERM_BP_FAT	GO:0032956~regulation of actin cytoskeleton organization	11	1.3664596273291925	0.013921005695303558	ACTR3, ARPC1A, ARPC2, NCK1, RHOQ, SPTBN1, ARF6, ARPC5, PROX1, DSTN, NEBL	683	89	13528	2.4480234260614937	1.0	0.21515200139249702	22.224510534949715
GOTERM_BP_FAT	GO:0015980~energy derivation by oxidation of organic compounds	15	1.8633540372670807	0.01394046480243127	UQCRC2, IL6ST, PHKA1, PRKAG2, GYG1, IDH3A, SOD2, SLC25A14, NNT, PPP1R2, PYGL, SDHC, DLD, NDUFV2, FH	683	144	13528	2.063201561737433	1.0	0.21428579510101375	22.25202356828898
GOTERM_CC_FAT	GO:0045178~basal part of cell	6	0.7453416149068323	0.014015014142122136	ACTR3, CAV2, CAV1, MET, ITGB4, DST	624	30	12782	4.096794871794872	0.9992931372461079	0.12150736116625216	18.45691987352668
SP_PIR_KEYWORDS	prenylated cysteine	5	0.6211180124223602	0.014050580934714375	RAB4A, RRAS2, PHKA1, RAB5A, RAB1A	802	23	19235	5.213867505150168	0.999325484569729	0.11109631235388884	18.50849705443126
UP_SEQ_FEATURE	repeat:TPR 5	9	1.1180124223602486	0.014068905457093734	RPAP3, KLC1, STIP1, SRP72, CDC16, OGT, SH3TC2, CDC27, GTF3C3	802	76	19113	2.822171544822155	0.9999999999999394	0.7186366975335878	21.77944982036052
GOTERM_BP_FAT	GO:0080135~regulation of cellular response to stress	12	1.4906832298136645	0.014568942482646736	MAP3K7, UBE2N, MAP4K5, NPC1, AIDA, LYN, PTPLAD1, USP1, NPM1, RIPK2, PDCD4, SYK	683	103	13528	2.3075807758461386	1.0	0.22168412675362537	23.13569635738486
GOTERM_BP_FAT	GO:0045935~positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	45	5.590062111801243	0.014679070139439015	ENY2, NCBP1, CNBP, ABLIM3, PRKDC, CASK, RHOQ, NFYB, NFYA, FOXO3, MED21, TCF7L2, POT1, NPAS2, ZNF148, TAF9, FOXO3B, RUNX1, FOSL1, MYC, RNF14, PLAGL2, BMP4, TBL1XR1, RAN, STRN3, CREB1, ILF3, DDX5, PROX1, STAT3, CDK2, GTF2H1, UBE2N, MED6, MAPK1, HHEX, MED7, YWHAH, ILF2, YAF2, MED17, UBC, MGEA5, BMP7, SMARCA4	683	624	13528	1.428370311972069	1.0	0.22201334191543354	23.289561816271565
INTERPRO	IPR004365:Nucleic acid binding, OB-fold, tRNA/helicase-type	4	0.4968944099378882	0.014847053468289228	RPA1, NARS2, DARS2, RPA4	753	12	16659	7.374501992031871	0.999999998580989	0.6577723927810963	21.77937920867401
SP_PIR_KEYWORDS	molecular chaperone	4	0.4968944099378882	0.015047703529024474	TCP1, HSPD1, CANX, HSPA8	802	13	19235	7.379627853443315	0.9995998325942946	0.11678318492050532	19.692480556763993
GOTERM_MF_FAT	GO:0003729~mRNA binding	9	1.1180124223602486	0.015402013558102725	HNRPDL, SERBP1, HNRNPD, GRSF1, ELAVL1, SYNCRIP, TSN, HNRNPC, SLBP	641	66	12983	2.7619486597645726	0.9999993617822548	0.2938423311729057	21.541461285208385
GOTERM_MF_FAT	GO:0042623~ATPase activity, coupled	23	2.857142857142857	0.015513012541139985	XRCC5, RBBP4, BRIP1, SKIV2L2, DDX5, ATP6V1D, GTF2H1, ATP6V1C1, RFC5, ATP6V1A, RFC3, DDX18, RFC4, CHD1L, PEX1, DDX3X, RFC1, RFC2, DDX19B, DHX15, ABCC1, HSPA8, SMARCA4	641	272	12983	1.712678948334404	0.9999994245974366	0.28972275774415035	21.679591620836725
GOTERM_BP_FAT	GO:0000279~M phase	27	3.354037267080745	0.015547586443529495	ANAPC10, CDC16, CCNG2, RPA1, TUBB, NUMA1, NIPBL, RANBP1, PAFAH1B1, ZWILCH, BUB3, STAG2, CDC6, MSH6, PDS5A, RAN, ILF3, CDC27, CDK2, SMC3, RAD1, DCLRE1A, NOLC1, TOP3A, CLIP1, MAPRE1, KPNA2	683	329	13528	1.625476731922014	1.0	0.23238029932795579	24.492863600030113
GOTERM_BP_FAT	GO:0000280~nuclear division	20	2.484472049689441	0.015629368140700463	CDC6, PDS5A, RAN, ANAPC10, CDC16, CDC27, CCNG2, CDK2, SMC3, NUMA1, TUBB, DCLRE1A, NIPBL, NOLC1, CLIP1, PAFAH1B1, MAPRE1, ZWILCH, BUB3, STAG2	683	220	13528	1.8006122720617597	1.0	0.23227005146325597	24.605246722601937
GOTERM_BP_FAT	GO:0007067~mitosis	20	2.484472049689441	0.015629368140700463	CDC6, PDS5A, RAN, ANAPC10, CDC16, CDC27, CCNG2, CDK2, SMC3, NUMA1, TUBB, DCLRE1A, NIPBL, NOLC1, CLIP1, PAFAH1B1, MAPRE1, ZWILCH, BUB3, STAG2	683	220	13528	1.8006122720617597	1.0	0.23227005146325597	24.605246722601937
GOTERM_BP_FAT	GO:0008285~negative regulation of cell proliferation	29	3.602484472049689	0.015689509235116354	CAV2, CAV1, CNOT8, IGFBP6, ABI1, SKAP2, MSX2, FNTB, WARS, PRKRA, NPM1, DLG3, CD24, ASPH, FOSL1, CUL1, BMP4, CDC6, GTPBP4, CGRRF1, RBBP4, NF1, GAL, CD164, PROX1, SOD2, CDKN1C, BMP7, TOB1	683	361	13528	1.5911227556446021	1.0	0.23187948010404424	24.68779086978924
INTERPRO	IPR000712:Apoptosis regulator Bcl-2, BH	5	0.6211180124223602	0.015740839486752263	BID, MCL1, BIK, BCL2L1, BCL2L13	753	22	16659	5.028069540021731	0.9999999995878152	0.6605665813471575	22.936622911069136
SMART	SM00173:RAS	5	0.6211180124223602	0.015792213832185965	RAP2B, RAP2C, RRAS2, RALB, RHEB	393	23	9079	5.0221263414094475	0.9784266322502657	0.42191955558020067	18.58413158745068
GOTERM_BP_FAT	GO:0006446~regulation of translational initiation	7	0.8695652173913043	0.016013362355823898	EIF4B, NCBP1, EIF2S1, EIF5, EIF1, ANKHD1, EIF2B3	683	41	13528	3.3816376816769633	1.0	0.23490135203660512	25.13081701731045
GOTERM_BP_FAT	GO:0002377~immunoglobulin production	6	0.7453416149068323	0.016034131781015225	MSH6, MSH3, SWAP70, MSH2, PRKDC, HSPD1	683	30	13528	3.961346998535871	1.0	0.2339965415453562	25.159145143021455
GOTERM_BP_FAT	GO:0009891~positive regulation of biosynthetic process	49	6.086956521739131	0.01625399367040092	HSP90AB1, ENY2, CASK, RHOQ, EIF5A, FOXO3, MED21, FNTA, ZNF148, FOXO3B, FOSL1, MYC, SYK, TBL1XR1, RAN, STRN3, PROX1, CDK2, GTF2H1, MED6, HHEX, MED7, MAPK1, MED17, UBC, SMARCA4, CNBP, ABLIM3, PRKDC, NFYB, NFYA, TCF7L2, POT1, NPAS2, NPM1, PRKAA1, TAF9, RUNX1, RNF14, PLAGL2, BMP4, CREB1, ILF3, DDX5, STAT3, SOD2, YWHAH, ILF2, YAF2, BMP7	683	695	13528	1.3964460642320697	1.0	0.2356415263617222	25.45840228049193
SP_PIR_KEYWORDS	amino-acid biosynthesis	5	0.6211180124223602	0.016317448325402176	MTHFD1, ALDH18A1, ENOPH1, PSAT1, MTRR	802	24	19235	4.996623025768911	0.9997943335216394	0.12422371693082646	21.177000702291117
GOTERM_CC_FAT	GO:0005624~membrane fraction	54	6.70807453416149	0.016571887717018903	SGPP1, PDLIM5, CASK, SYNCRIP, FOXO3, SLC16A1, PGRMC1, SLC2A1, RC3H2, FOXO3B, FOSL1, LYN, AIFM1, SLC33A1, RAB4A, MGAT2, PSEN1, SQLE, RAB14, RAB5A, VAMP3, TOMM22, EMP1, DEGS1, BID, CAV2, CAV1, GNAI3, ATG12, ARFRP1, ARF6, ABI1, FKBP1A, LMAN1, ACSL1, TMED2, SH3GLB1, SLC30A5, PAFAH1B1, PPP3CA, CD24, MOBKL3, EBP, RYK, SEC11A, MET, LIN7C, RGS19, VDAC3, PPIF, LAMP1, LAMP2, CD59, ABCC1, SPCS2	624	809	12782	1.367286298374061	0.9998139172555531	0.13988554306642542	21.46107256952363
GOTERM_BP_FAT	GO:0043627~response to estrogen stimulus	12	1.4906832298136645	0.01663759587051114	BMP4, CAV2, MAPK1, CAV1, SOCS2, LDLR, STRN3, CD24, GAL, BMP7, RNF14, STAT3	683	105	13528	2.263626856306212	1.0	0.23933289416531667	25.97782508307992
SP_PIR_KEYWORDS	alternative initiation	8	0.9937888198757764	0.0167647537881134	CAV2, GSR, CAV1, TAF12, BAG1, TH1L, FH, ENO1	802	64	19235	2.997973815461347	0.9998373559390288	0.125597567578428	21.693853730226852
GOTERM_BP_FAT	GO:0006412~translation	27	3.354037267080745	0.016800053789428407	MRPL42, MRPS15, HBS1L, EIF5, EIF5A, MRPS30, WARS, MRPL13, NARS2, MRPL19, RPL3, MRPL18, EIF1, TPR, EIF2B3, EIF3M, PAIP1, MRPL9, DARS2, MRPS7, SELT, GTF2B, EIF4B, LOC645139, HNRNPH2, EIF4E, EIF2S1, UBC	683	331	13528	1.6156551202487694	1.0	0.24020103773163148	26.19677207439234
SMART	SM00533:MUTSd	3	0.37267080745341613	0.017049392585729656	MSH6, MSH3, MSH2	393	5	9079	13.861068702290076	0.9841460097204744	0.4043140958012963	19.917177044184122
GOTERM_CC_FAT	GO:0031252~cell leading edge	14	1.7391304347826086	0.017177512701512042	SWAP70, ABI2, ABI1, ARF6, ACTR3, PTK2, CTTN, ARPC2, LOC100129652, RAB5A, PIK3CA, PAFAH1B1, APBB2, PARVA	624	138	12782	2.0780843552582686	0.9998644206502942	0.14234291062153048	22.15738691195862
GOTERM_BP_FAT	GO:0032970~regulation of actin filament-based process	11	1.3664596273291925	0.01727302426912107	ACTR3, ARPC1A, ARPC2, NCK1, RHOQ, SPTBN1, ARF6, ARPC5, PROX1, DSTN, NEBL	683	92	13528	2.368196575211662	1.0	0.24491472120591506	26.830725176939264
INTERPRO	IPR003960:ATPase, AAA-type, conserved site	6	0.7453416149068323	0.017369383125528423	PSMC6, PEX1, PSMC3, PSMC2, ATAD2, YME1L1	753	34	16659	3.904148113428638	0.9999999999567907	0.67903618946485	25.00397841155181
GOTERM_BP_FAT	GO:0034097~response to cytokine stimulus	10	1.2422360248447204	0.017598368270150187	FNTA, ADAM10, MCL1, IL6ST, RIPK2, TAF9, BCL2L1, STAT1, FOSL1, STAT3	683	79	13528	2.5071816446429565	1.0	0.2477396504189725	27.263816173828037
GOTERM_BP_FAT	GO:0070507~regulation of microtubule cytoskeleton organization	7	0.8695652173913043	0.017910181435828378	CAV2, CAV1, CEP76, NPM1, RANBP1, MAPRE1, DST	683	42	13528	3.301122498779893	1.0	0.25035961703921406	27.676622702944453
GOTERM_BP_FAT	GO:0045941~positive regulation of transcription	41	5.093167701863354	0.018002277974035693	ENY2, CNBP, ABLIM3, PRKDC, CASK, RHOQ, NFYB, NFYA, FOXO3, MED21, TCF7L2, NPAS2, ZNF148, TAF9, FOXO3B, RUNX1, MYC, FOSL1, RNF14, PLAGL2, BMP4, TBL1XR1, RAN, STRN3, CREB1, ILF3, DDX5, PROX1, STAT3, CDK2, GTF2H1, MED6, MAPK1, HHEX, MED7, YWHAH, ILF2, YAF2, MED17, UBC, BMP7, SMARCA4	683	564	13528	1.439851302659315	1.0	0.2502874866095075	27.798124628982634
GOTERM_BP_FAT	GO:0010628~positive regulation of gene expression	42	5.217391304347826	0.01806878874034744	ENY2, CNBP, ABLIM3, PRKDC, CASK, RHOQ, NFYB, NFYA, FOXO3, MED21, TCF7L2, NPAS2, ZNF148, TAF9, FOXO3B, RUNX1, FOSL1, MYC, RNF14, PLAGL2, BMP4, TBL1XR1, RAN, STRN3, CREB1, ILF3, DDX5, PROX1, STAT3, CDK2, GTF2H1, MED6, MAPK1, HHEX, MED7, YWHAH, ILF2, YAF2, MED17, UBC, MAPK9, BMP7, SMARCA4	683	581	13528	1.4318121681454956	1.0	0.24990806935343457	27.88575164992905
SP_PIR_KEYWORDS	activator	33	4.099378881987578	0.01807106431487123	ENY2, CREM, NFYB, TRRAP, FOXO3, NFYA, MED21, TCF7L2, PNN, NONO, MAX, BZW1L1, ARNTL2, FOXO3B, MYC, TFDP1, PLAGL2, CREBL2, NFX1, TBL1XR1, SUB1, CREB1, ATAD2, CDC5L, STAT1, STAT3, MED6, HNRPDL, MED7, RFC1, ILF2, MED17, FLII, SMARCA4	802	520	19235	1.5220482447726835	0.9999180950824451	0.13287750237780915	23.185268381034476
GOTERM_CC_FAT	GO:0031966~mitochondrial membrane	30	3.7267080745341614	0.018221452249514013	UQCRC2, HCCS, BID, ALDH18A1, MCL1, TIMM17A, BCL2L1, ACSL1, SH3GLB1, ATP5S, SLC25A46, AGK, GPD2, DNM1L, LYN, AK2, TMEM70, TIMM23, VDAC3, TIMM8A, SOD2, PPIF, SLC25A14, NNT, PSEN1, SDHC, NDUFV2, TOMM22, HSPD1, AKAP1	624	394	12782	1.559693479109723	0.9999214839003144	0.1480324979187715	23.344178227234092
GOTERM_BP_FAT	GO:0022406~membrane docking	6	0.7453416149068323	0.018346402094515935	CAV2, ROCK1, LOC100129652, VTI1B, VAMP3, EXOC5	683	31	13528	3.8335616114863273	1.0	0.2520594174275894	28.25042030594632
GOTERM_BP_FAT	GO:0002440~production of molecular mediator of immune response	6	0.7453416149068323	0.018346402094515935	MSH6, MSH3, SWAP70, MSH2, PRKDC, HSPD1	683	31	13528	3.8335616114863273	1.0	0.2520594174275894	28.25042030594632
GOTERM_BP_FAT	GO:0006084~acetyl-CoA metabolic process	6	0.7453416149068323	0.018346402094515935	NNT, SDHC, DLD, DLAT, IDH3A, FH	683	31	13528	3.8335616114863273	1.0	0.2520594174275894	28.25042030594632
INTERPRO	IPR003577:Ras small GTPase, Ras type	5	0.6211180124223602	0.01838995988859221	RAP2B, RAP2C, RRAS2, RALB, RHEB	753	23	16659	4.809457820890351	0.9999999999895068	0.6830795161738241	26.272880781534845
GOTERM_BP_FAT	GO:0000087~M phase of mitotic cell cycle	20	2.484472049689441	0.01855621464012954	CDC6, PDS5A, RAN, ANAPC10, CDC16, CDC27, CCNG2, CDK2, SMC3, NUMA1, TUBB, DCLRE1A, NIPBL, NOLC1, CLIP1, PAFAH1B1, MAPRE1, ZWILCH, BUB3, STAG2	683	224	13528	1.7684584814892281	1.0	0.25337814591687324	28.52487084544315
INTERPRO	IPR003151:PIK-related kinase, FAT	3	0.37267080745341613	0.018579426090580692	PRKDC, ATR, TRRAP	753	5	16659	13.27410358565737	0.9999999999919328	0.670630253278292	26.50621743649729
INTERPRO	IPR007696:DNA mismatch repair protein MutS, core	3	0.37267080745341613	0.018579426090580692	MSH6, MSH3, MSH2	753	5	16659	13.27410358565737	0.9999999999919328	0.670630253278292	26.50621743649729
GOTERM_BP_FAT	GO:0014070~response to organic cyclic substance	13	1.6149068322981366	0.018954506475203012	BMP4, LYN, MSH2, TAF9B, FKBP1A, BCL2L1, STAT1, STAT3, ACSL1, FNTA, CHRNA5, SRR, FOSL1	683	121	13528	2.1279963215275344	1.0	0.2568991894213659	29.04314171125494
INTERPRO	IPR001806:Ras GTPase	13	1.6149068322981366	0.01917077181816363	RAP2B, RAP2C, RAB9A, RAB4A, ARFRP1, RHOQ, RAB1A, RRAS2, RAB22A, RALB, RAB14, RAB5A, RHEB	753	135	16659	2.130411686586985	0.9999999999964502	0.6666308563805501	27.230035657543418
SP_PIR_KEYWORDS	Protease	31	3.8509316770186333	0.019806803575783592	ERMP1, METAP2, AMZ2, IDE, F2RL1, LOC440434, USP34, PCSK5, KLK7, TMPRSS2, CAPN7, ADAM10, OSGEP, USP1, SEC11A, OSGEPL1, CAPN2, XPNPEP1, PSMA2, SENP2, PSMA1, SENP3, BLMH, PSEN1, PSMA5, PSMA3, UCHL5, YME1L1, SPCS2, ADAM19, PLAU	802	484	19235	1.5361518723851528	0.9999671277976226	0.14279045738195606	25.126073177620235
GOTERM_BP_FAT	GO:0002253~activation of immune response	11	1.3664596273291925	0.019816626660641712	MAP3K7, UBE2N, MAPK1, CD55, PSEN1, LYN, FYN, CD46, RIPK2, HSPD1, SYK	683	94	13528	2.3178094140369456	1.0	0.26574874547971405	30.15283433971557
GOTERM_BP_FAT	GO:0045190~isotype switching	4	0.4968944099378882	0.019945185256851822	MSH6, SWAP70, MSH2, HSPD1	683	12	13528	6.602244997559786	1.0	0.2660206881166518	30.316899950436138
GOTERM_BP_FAT	GO:0002208~somatic diversification of immunoglobulins during immune response	4	0.4968944099378882	0.019945185256851822	MSH6, SWAP70, MSH2, HSPD1	683	12	13528	6.602244997559786	1.0	0.2660206881166518	30.316899950436138
GOTERM_BP_FAT	GO:0030838~positive regulation of actin filament polymerization	4	0.4968944099378882	0.019945185256851822	ACTR3, ARPC2, NCK1, ARF6	683	12	13528	6.602244997559786	1.0	0.2660206881166518	30.316899950436138
GOTERM_BP_FAT	GO:0002204~somatic recombination of immunoglobulin genes during immune response	4	0.4968944099378882	0.019945185256851822	MSH6, SWAP70, MSH2, HSPD1	683	12	13528	6.602244997559786	1.0	0.2660206881166518	30.316899950436138
GOTERM_CC_FAT	GO:0030027~lamellipodium	9	1.1180124223602486	0.02009719275961961	ACTR3, CTTN, PTK2, SWAP70, ABI2, PIK3CA, ABI1, APBB2, PARVA	624	70	12782	2.6336538461538463	0.9999706192452958	0.15963546552093233	25.434378688508453
SP_PIR_KEYWORDS	Initiation factor	7	0.8695652173913043	0.020447878151164525	EIF4B, EIF4E, EIF2S1, EIF5, EIF1, EIF2B3, EIF3M	802	52	19235	3.2285871858814503	0.9999765460688349	0.14510075020234314	25.831269696527713
GOTERM_BP_FAT	GO:0051276~chromosome organization	36	4.472049689440994	0.020545815216078324	XRCC5, ENY2, MORF4, PRKDC, CBX3, CBX1, TRRAP, POT1, RPA1, NIPBL, SET, CHD1L, CDYL, H2AFV, PRMT5, SAFB, NPM1, TAF9, TLK2, BUB3, MSH6, TBL1XR1, UBE2A, RBBP4, SMCHD1, MSH3, AIFM1, MSH2, SMC3, UBE2N, MSL3, TAF12, RFC1, H3F3B, HDAC9, SMARCA4	683	485	13528	1.47019063863187	1.0	0.2716685944492203	31.078610079539704
GOTERM_BP_FAT	GO:0051130~positive regulation of cellular component organization	17	2.111801242236025	0.02070187702954731	CAV2, CAV1, RHOQ, EIF5A, ARF6, PROX1, POT1, DSTN, UBE2N, ACTR3, SUMO1, ARPC2, NCK1, NPM1, MGEA5, RANBP1, CD24	683	181	13528	1.8603010766604922	1.0	0.272216092856046	31.275234737562364
GOTERM_MF_FAT	GO:0004386~helicase activity	14	1.7391304347826086	0.020803787242694487	XRCC5, BRIP1, SKIV2L2, DDX5, MCM4, ATRX, DDX18, CHD1L, MCM7, DDX3X, NAV2, DDX19B, DHX15, SMARCA4	641	140	12983	2.0254290171606866	0.9999999959329703	0.3619320728434492	28.005756305074147
GOTERM_BP_FAT	GO:0000245~spliceosome assembly	6	0.7453416149068323	0.020868066630138574	SRPK2, SNRPD1, SFRS2IP, MBNL1, SIP1, SFRS1	683	32	13528	3.713762811127379	1.0	0.272871384801709	31.484037153623245
SP_PIR_KEYWORDS	hydrolase	82	10.186335403726709	0.021086148513343384	XRCC5, UQCRC2, METAP2, SGPP1, IDE, SKIV2L2, ACOT9, MTHFD1, DDX18, HRSP12, ENOPH1, PDE8A, EXOSC9, ADAM10, NUDT4, USP1, EXOSC2, OSGEPL1, GNS, PSMA2, SENP2, RAD1, PSMA1, ATP6V1A, SENP3, BLMH, PRUNE, PSEN1, NAV2, PSMA5, PSMA3, UCHL5, MGEA5, YME1L1, ADAM19, SMARCA4, ERMP1, ABHD6, AMZ2, ABHD2, OCRL, ACP1, MTMR2, LOC440434, CHD1L, ACSL1, DDX3X, DDX19B, DHX15, PPP3CA, C12ORF5, USP34, GAPDH, PCSK5, FEN1, DCTD, CAPN7, TMPRSS2, KLK7, DNM1L, LIPA, OSGEP, GDE1, SEC11A, GGH, BRIP1, ATAD2, DDX5, CAPN2, PTPN12, XPNPEP1, PPA1, ATRX, PTP4A1, GLS, TDP1, PTP4A2, PON2, ABCC1, SPCS2, HDAC9, PLAU	802	1555	19235	1.2647400790627932	0.9999832448447218	0.14732258433888012	26.52723528036567
SP_PIR_KEYWORDS	translation regulation	8	0.9937888198757764	0.021108904984029078	LOC645139, NCBP1, EIF4E, EIF2S1, PAIP1, MAGOH, NCK1, NGDN, ANKHD1	802	67	19235	2.8637361819332265	0.9999834446290758	0.1455254592259828	26.55193617790459
INTERPRO	IPR003095:Heat shock protein DnaJ	5	0.6211180124223602	0.021299469907904614	DNAJC10, DNAJA1, DNAJB1, SEC63, DNAJA2	753	24	16659	4.60906374501992	0.9999999999998159	0.6905415209224628	29.78055928709642
GOTERM_CC_FAT	GO:0017059~serine C-palmitoyltransferase complex	3	0.37267080745341613	0.021497618805947673	C14ORF147, SPTLC1, SPTLC2	624	5	12782	12.290384615384616	0.9999859132812634	0.16733119901766724	26.96019533988072
GOTERM_CC_FAT	GO:0031211~palmitoyltransferase complex	3	0.37267080745341613	0.021497618805947673	C14ORF147, SPTLC1, SPTLC2	624	5	12782	12.290384615384616	0.9999859132812634	0.16733119901766724	26.96019533988072
GOTERM_MF_FAT	GO:0003725~double-stranded RNA binding	6	0.7453416149068323	0.021646606575776516	NKRF, ILF2, PRKRA, ILF3, MBNL1, STAU1	641	33	12983	3.68259821301943	0.9999999981566853	0.3668729083871046	28.96820412073525
SMART	SM00326:SH3	17	2.111801242236025	0.02195515562571311	LYN, ABI2, ASAP1, CASK, ABI1, SKAP2, NEBL, DOCK4, TJP1, CTTN, SH3GLB1, FYN, NCK1, DLG3, SH3TC2, CRK, DLG1	393	213	9079	1.8438041309775532	0.9952525203515459	0.44813959588675234	24.928716016034812
GOTERM_MF_FAT	GO:0017056~structural constituent of nuclear pore	3	0.37267080745341613	0.021965638853589417	NUP98, TMEM48, NUP155	641	5	12983	12.15257410296412	0.9999999986340654	0.3646550922060088	29.329366862145754
GOTERM_MF_FAT	GO:0004758~serine C-palmitoyltransferase activity	3	0.37267080745341613	0.021965638853589417	C14ORF147, SPTLC1, SPTLC2	641	5	12983	12.15257410296412	0.9999999986340654	0.3646550922060088	29.329366862145754
GOTERM_MF_FAT	GO:0016454~C-palmitoyltransferase activity	3	0.37267080745341613	0.021965638853589417	C14ORF147, SPTLC1, SPTLC2	641	5	12983	12.15257410296412	0.9999999986340654	0.3646550922060088	29.329366862145754
SP_PIR_KEYWORDS	myristylation	6	0.7453416149068323	0.0220603883678244	GNAI3, LYN, FYN, ARF3, ARF4, ARF6	802	39	19235	3.6898139267216568	0.9999899766836896	0.14966175906586465	27.57782759553934
GOTERM_CC_FAT	GO:0005769~early endosome	10	1.2422360248447204	0.02231504137368498	PTP4A1, RAB22A, PTP4A2, RAB5A, RAB14, ARF6, PRDX3, HSPD1, ANXA2P2, ANXA2	624	85	12782	2.4098793363499245	0.9999908324782487	0.17063443586368554	27.837322899028692
GOTERM_CC_FAT	GO:0045121~membrane raft	14	1.7391304347826086	0.022393430692488447	CAV2, CAV1, GNAI3, LYN, LDLR, RHOQ, TUBB, CD55, PSEN1, SLC2A1, RAB5A, LRP8, CD24, BMPR1A	624	143	12782	2.005424063116371	0.9999912026231699	0.16871175748571154	27.920920558976903
UP_SEQ_FEATURE	topological domain:Vesicular	6	0.7453416149068323	0.02260424596143301	SYT1, SYPL1, VAMP7, VTI1B, GOSR2, VAMP3	802	39	19113	3.66641089583733	1.0	0.8597661373141438	32.72461612213144
GOTERM_BP_FAT	GO:0050435~beta-amyloid metabolic process	3	0.37267080745341613	0.022923167569217334	PSEN1, IDE, FKBP1A	683	5	13528	11.884040995607613	1.0	0.29430667517016285	34.01707980191031
KEGG_PATHWAY	hsa00471:D-Glutamine and D-glutamate metabolism	3	0.37267080745341613	0.022948597342914084	GLUD2, GLUD1, GLS	330	4	5085	11.556818181818182	0.9744758562371958	0.2633758858307642	24.40107858818822
GOTERM_CC_FAT	GO:0005815~microtubule organizing center	21	2.608695652173913	0.023134637370070828	TCP1, ROCK1, CEP192, CEP76, C21ORF33, CDC16, SMEK1, CDC27, DCTN4, TUBGCP4, CEP57, LOC100129652, NPM1, NUDT21, FLII, RANBP1, PAFAH1B1, MAPRE1, MYOF, CALM1, KIF2A	624	253	12782	1.7002508361204012	0.9999940428113407	0.171371204768637	28.706930690592948
GOTERM_BP_FAT	GO:0006357~regulation of transcription from RNA polymerase II promoter	50	6.211180124223603	0.023322705352131164	CASK, RHOQ, DEK, FOXO3, MED21, TCEAL1, GABPB1, ZNF148, FOXO3B, FOSL1, MYC, NFX1, TBL1XR1, STRN3, PROX1, GTF2H1, MED6, HHEX, MED7, MED17, C19ORF2, SMARCA4, EID1, CNBP, ABLIM3, TAF9B, PRKDC, NFYA, TCF7L2, ORC2L, NPAS2, TAF9, RUNX1, RNF14, PLAGL2, ENO1, TFDP1, BMP4, SUB1, CREB1, BRIP1, SNW1, TFCP2, STAT3, SOD2, CDKN1C, DR1, PRKAR1A, HDAC9, BMP7, CRK	683	727	13528	1.3622238646959666	1.0	0.2973415041456907	34.49915545619518
GOTERM_MF_FAT	GO:0032561~guanyl ribonucleotide binding	29	3.602484472049689	0.023375691853746165	RAB9A, GNAI3, GLUD2, GLUD1, ARFRP1, HBS1L, EIF5, RHOQ, ARF6, RAB1A, TUBB, LANCL2, RALB, RAP2B, GTPBP4, DNM1L, RAP2C, RAN, RAB4A, DRG2, NOLC1, RRAS2, ARF3, RAB22A, ARF4, RAB5A, RAB14, RHEB, PRPS1	641	382	12983	1.5376293585774845	0.9999999996372564	0.3765897943052531	30.90513763934599
GOTERM_MF_FAT	GO:0019001~guanyl nucleotide binding	29	3.602484472049689	0.023375691853746165	RAB9A, GNAI3, GLUD2, GLUD1, ARFRP1, HBS1L, EIF5, RHOQ, ARF6, RAB1A, TUBB, LANCL2, RALB, RAP2B, GTPBP4, DNM1L, RAP2C, RAN, RAB4A, DRG2, NOLC1, RRAS2, ARF3, RAB22A, ARF4, RAB5A, RAB14, RHEB, PRPS1	641	382	12983	1.5376293585774845	0.9999999996372564	0.3765897943052531	30.90513763934599
UP_SEQ_FEATURE	repeat:TPR 6	8	0.9937888198757764	0.02342081279337257	RPAP3, KLC1, STIP1, CDC16, OGT, SH3TC2, CDC27, GTF3C3	802	68	19113	2.8037259791697227	1.0	0.8588508679478326	33.69239934048901
UP_SEQ_FEATURE	region of interest:NLS binding site (minor)	3	0.37267080745341613	0.0235146204335277	KPNA4, KPNA2, KPNA1	802	6	19113	11.915835411471322	1.0	0.8493904129366145	33.80273480024905
UP_SEQ_FEATURE	repeat:ARM 10; atypical	3	0.37267080745341613	0.0235146204335277	KPNA4, KPNA2, KPNA1	802	6	19113	11.915835411471322	1.0	0.8493904129366145	33.80273480024905
UP_SEQ_FEATURE	domain:FATC	3	0.37267080745341613	0.0235146204335277	PRKDC, ATR, TRRAP	802	6	19113	11.915835411471322	1.0	0.8493904129366145	33.80273480024905
UP_SEQ_FEATURE	domain:FAT	3	0.37267080745341613	0.0235146204335277	PRKDC, ATR, TRRAP	802	6	19113	11.915835411471322	1.0	0.8493904129366145	33.80273480024905
UP_SEQ_FEATURE	region of interest:NLS binding site (major)	3	0.37267080745341613	0.0235146204335277	KPNA4, KPNA2, KPNA1	802	6	19113	11.915835411471322	1.0	0.8493904129366145	33.80273480024905
UP_SEQ_FEATURE	repeat:ARM 1; truncated	3	0.37267080745341613	0.0235146204335277	KPNA4, KPNA2, KPNA1	802	6	19113	11.915835411471322	1.0	0.8493904129366145	33.80273480024905
GOTERM_BP_FAT	GO:0006352~transcription initiation	10	1.2422360248447204	0.023571701291523414	MED7, TAF12, POLR2K, MED17, TAF9B, TAF9, GTF2B, MYC, GTF3C4, GTF2H1	683	83	13528	2.386353613575826	1.0	0.29872724088838576	34.797905654130254
GOTERM_BP_FAT	GO:0006612~protein targeting to membrane	6	0.7453416149068323	0.023605404056506435	MGEA5, PEX3, SRP72, SEC63, SSR1, TIMM8A	683	33	13528	3.6012245441235193	1.0	0.2978087191799177	34.838243890018816
GOTERM_BP_FAT	GO:0006406~mRNA export from nucleus	6	0.7453416149068323	0.023605404056506435	HHEX, NCBP1, DDX19B, EIF5A, GLE1, THOC2	683	33	13528	3.6012245441235193	1.0	0.2978087191799177	34.838243890018816
GOTERM_CC_FAT	GO:0070461~SAGA-type complex	5	0.6211180124223602	0.023643153375583224	ENY2, TAF12, TAF9B, TAF9, TRRAP	624	23	12782	4.4530379041248604	0.9999954416455025	0.17238602239487855	29.241562226788865
SP_PIR_KEYWORDS	helicase	12	1.4906832298136645	0.02437486594578591	ATRX, XRCC5, DDX18, CHD1L, DDX3X, NAV2, DDX19B, DHX15, BRIP1, SKIV2L2, DDX5, SMARCA4	802	134	19235	2.14780213644992	0.9999970486703473	0.16209517635093906	30.017883717320657
GOTERM_BP_FAT	GO:0006413~translational initiation	7	0.8695652173913043	0.024509511323357065	LOC645139, EIF4E, PAIP1, EIF5, EIF1, EIF2B3, GTF2B, EIF3M	683	45	13528	3.0810476655278998	1.0	0.3060714570867268	35.91160016414332
GOTERM_MF_FAT	GO:0019201~nucleotide kinase activity	5	0.6211180124223602	0.024533752548306205	CASK, DLG3, AK2, TAF9, DLG1	641	23	12983	4.4031065590449705	0.9999999998780856	0.38473105464440926	32.17463983642275
SMART	SM00534:MUTSac	3	0.37267080745341613	0.024849519823060943	MSH6, MSH3, MSH2	393	6	9079	11.55089058524173	0.9976758455448949	0.4547112990884634	27.748098175250124
SP_PIR_KEYWORDS	cytoskeleton	38	4.720496894409938	0.024851780673885653	CEP76, ITGB4, AKAP12, ABI2, ABI1, ARPC4, CDC16, ARPC5, TPM4, TUBGCP4, ACTR3, GPHN, CTTN, CEP57, ARPC2, LOC100129652, SNTB1, PAFAH1B1, STK38L, CDC42EP3, KIF2A, CSNK1A1, ACTB, ROCK1, CEP192, SMEK1, DCTN4, ARPC1A, SVIL, PTP4A1, CLIP1, SPTBN1, FLII, WDR1, MAPRE1, DST, CALM1, PARVA	802	636	19235	1.432993773428065	0.9999977067777966	0.16296072238033854	30.511068949167395
GOTERM_BP_FAT	GO:0002381~immunoglobulin production during immune response	4	0.4968944099378882	0.024975670653608895	MSH6, SWAP70, MSH2, HSPD1	683	13	13528	6.094379997747494	1.0	0.30963435951497387	36.45848015677363
SP_PIR_KEYWORDS	protein biosynthesis	15	1.8633540372670807	0.025892178336802758	METAP2, HBS1L, EIF5, EIF5A, DARS2, EIF4B, WARS, EIF4E, NARS2, EIF2S1, RPL3, UBC, EIF1, EIF2B3, EIF3M	802	188	19235	1.913600307741285	0.9999986780112271	0.16716852119359515	31.57575493031238
GOTERM_BP_FAT	GO:0006163~purine nucleotide metabolic process	17	2.111801242236025	0.025946195347486538	MSH2, PRKAG2, RHOQ, ACLY, HPRT1, ATP6V1D, GART, ATP6V1C1, MTHFD1, ATP6V1A, ATP5S, ADK, MGEA5, PDE8A, PAICS, ATP6V0A2, PRPS1	683	186	13528	1.8102929832018766	1.0	0.3183086176916228	37.582957208047404
GOTERM_BP_FAT	GO:0009165~nucleotide biosynthetic process	17	2.111801242236025	0.025946195347486538	DCTD, NAMPT, MSH2, PRKAG2, CTPS2, HPRT1, ATP6V1D, GART, ATP6V1C1, MTHFD1, ATP6V1A, ATP5S, ADK, RRM1, PAICS, ATP6V0A2, PRPS1	683	186	13528	1.8102929832018766	1.0	0.3183086176916228	37.582957208047404
GOTERM_BP_FAT	GO:0006986~response to unfolded protein	9	1.1180124223602486	0.025966933248607545	HSP90AB1, DERL1, DNAJA1, HSPA4, DNAJB1, HSPD1, UBXN4, DNAJB6, HSPA8	683	71	13528	2.5107128863959747	1.0	0.3172055999473088	37.606778419243426
GOTERM_BP_FAT	GO:0009112~nucleobase metabolic process	5	0.6211180124223602	0.026393096833433178	MAPK1, HPRT1, PAICS, GART, PRPS1	683	23	13528	4.305811954930295	1.0	0.32020809244846404	38.09440737303039
GOTERM_BP_FAT	GO:0032774~RNA biosynthetic process	24	2.981366459627329	0.026487474234664233	COPS2, POLR3K, POLR2K, CREB1, TAF9B, NFYA, STAT1, GTF2B, YBX1, GTF2H1, PRIM1, FUBP1, MSL3, MED7, MAX, TAF12, MED17, PIR, TAF9, MYC, FOSL1, GTF3C4, GTF3C3, NFX1	683	296	13528	1.6059514858929207	1.0	0.3198488301478901	38.20190899309265
GOTERM_BP_FAT	GO:0070585~protein localization in mitochondrion	6	0.7453416149068323	0.026564040863010053	BID, YWHAZ, TIMM17A, TOMM22, TIMM23, TIMM8A	683	34	13528	3.49530617517871	1.0	0.3193151137735839	38.28899352081323
GOTERM_BP_FAT	GO:0006626~protein targeting to mitochondrion	6	0.7453416149068323	0.026564040863010053	BID, YWHAZ, TIMM17A, TOMM22, TIMM23, TIMM8A	683	34	13528	3.49530617517871	1.0	0.3193151137735839	38.28899352081323
SP_PIR_KEYWORDS	membrane trafficking	4	0.4968944099378882	0.02685989555375668	SYT1, RAB4A, RAB5A, RAB1A	802	16	19235	5.995947630922694	0.9999992084263426	0.1708243285917841	32.55241421708993
GOTERM_MF_FAT	GO:0003714~transcription corepressor activity	14	1.7391304347826086	0.02686881424144629	TBL1XR1, EID1, COPS2, TAF9B, RBM9, PROX1, SFRS2, YAF2, PSMC3, DR1, C19ORF2, HDAC9, ENO1, TOB1	641	145	12983	1.955586637258594	0.9999999999865257	0.40634871166366593	34.66829711274505
GOTERM_MF_FAT	GO:0051287~NAD or NADH binding	7	0.8695652173913043	0.026983417048927757	ME2, NNT, GLUD1, NDUFV2, DLD, GAPDH, IDH3A	641	47	12983	3.016596408537193	0.9999999999879079	0.4013211368497578	34.78844625054711
INTERPRO	IPR000432:DNA mismatch repair protein MutS, C-terminal	3	0.37267080745341613	0.027042236282841556	MSH6, MSH3, MSH2	753	6	16659	11.061752988047807	0.9999999999999999	0.7621472736304058	36.248991004992305
INTERPRO	IPR014009:PIK-related kinase	3	0.37267080745341613	0.027042236282841556	PRKDC, ATR, TRRAP	753	6	16659	11.061752988047807	0.9999999999999999	0.7621472736304058	36.248991004992305
INTERPRO	IPR003152:PIK-related kinase, FATC	3	0.37267080745341613	0.027042236282841556	PRKDC, ATR, TRRAP	753	6	16659	11.061752988047807	0.9999999999999999	0.7621472736304058	36.248991004992305
UP_SEQ_FEATURE	compositionally biased region:Arg/Ser-rich (RS domain)	4	0.4968944099378882	0.027306645654359026	SFRS7, SFRS1, SFRS3, SFRS2	802	16	19113	5.95791770573566	1.0	0.8804406645572892	38.12077479329798
INTERPRO	IPR002423:Chaperonin Cpn60/TCP-1	4	0.4968944099378882	0.027771723372295914	CCT5, TCP1, CCT2, HSPD1	753	15	16659	5.899601593625498	1.0	0.7584672252682871	37.02937961840491
GOTERM_MF_FAT	GO:0046983~protein dimerization activity	38	4.720496894409938	0.027809873683079467	CAV2, RAB3GAP2, MCL1, IL6ST, CREM, IDE, POLA1, BCL2L1, HPRT1, TPD52, MTMR2, BATF, MAX, GSR, CEP57, SH3GLB1, PRKRA, NPM1, SRR, PAFAH1B1, PPP3CA, RUNX1, FOSL1, CREBL2, BMP4, ADAM10, MSH3, BRAF, MSH2, CREB1, SMC3, STAT3, INHBB, PYGL, CLIP1, PDCD6, BMPR1A, PRPS1	641	542	12983	1.420042484356201	0.999999999994462	0.4045200180820059	35.64879598932077
GOTERM_CC_FAT	GO:0030894~replisome	4	0.4968944099378882	0.028052671490628706	RPA1, PRIM1, POLA1, RPA4	624	14	12782	5.852564102564102	0.9999995549965001	0.19875915144372813	33.723534565988835
GOTERM_CC_FAT	GO:0043601~nuclear replisome	4	0.4968944099378882	0.028052671490628706	RPA1, PRIM1, POLA1, RPA4	624	14	12782	5.852564102564102	0.9999995549965001	0.19875915144372813	33.723534565988835
GOTERM_CC_FAT	GO:0033276~transcription factor TFTC complex	4	0.4968944099378882	0.028052671490628706	TAF12, TAF9B, TAF9, TRRAP	624	14	12782	5.852564102564102	0.9999995549965001	0.19875915144372813	33.723534565988835
UP_SEQ_FEATURE	domain:LisH	5	0.6211180124223602	0.028164781565957555	SMU1, TBL1XR1, RANBP9, NOLC1, PAFAH1B1	802	28	19113	4.2556555040969	1.0	0.8794966292960371	39.060411498006
GOTERM_CC_FAT	GO:0000313~organellar ribosome	7	0.8695652173913043	0.02820192189351621	MRPL42, MRPL13, MRPS28, MRPS15, MRPL18, MRPL9, MRPL39	624	48	12782	2.9872462606837606	0.9999995887722433	0.19705130366164092	33.87050882278886
GOTERM_CC_FAT	GO:0005761~mitochondrial ribosome	7	0.8695652173913043	0.02820192189351621	MRPL42, MRPL13, MRPS28, MRPS15, MRPL18, MRPL9, MRPL39	624	48	12782	2.9872462606837606	0.9999995887722433	0.19705130366164092	33.87050882278886
GOTERM_BP_FAT	GO:0031328~positive regulation of cellular biosynthetic process	47	5.838509316770186	0.028225873181226414	ENY2, HSP90AB1, CNBP, ABLIM3, PRKDC, CASK, RHOQ, EIF5A, NFYB, NFYA, FOXO3, MED21, TCF7L2, POT1, NPAS2, ZNF148, NPM1, TAF9, FOXO3B, RUNX1, FOSL1, MYC, RNF14, SYK, PLAGL2, BMP4, TBL1XR1, RAN, STRN3, CREB1, ILF3, DDX5, PROX1, STAT3, CDK2, GTF2H1, SOD2, MED6, MAPK1, HHEX, MED7, YWHAH, ILF2, YAF2, MED17, UBC, BMP7, SMARCA4	683	685	13528	1.3590022549721603	1.0	0.3343905978909043	40.15080331426727
GOTERM_CC_FAT	GO:0005794~Golgi apparatus	56	6.956521739130435	0.0282494071490032	RAB9A, F2RL1, IGFBP6, PITPNB, UXS1, RAB1A, ACTR3, PICALM, ZNF148, AP3B1, SEC23A, SCAMP1, ADAM10, LYN, ROCK1, STRN3, VTI1B, GAL, MGAT2, PSEN1, SCYL2, VAMP7, NAB1, RAB14, MAPRE1, TMCO1, CAV2, CAV1, GNAI3, CNIH, ARFRP1, STIP1, ARF6, OCRL, LMAN1, CALU, MTHFS, TMED2, CEP57, ARPC2, SH3GLB1, GORASP2, SLC30A5, B3GNT2, PCSK5, B4GALT4, MOBKL3, GDI2, DNM1L, RGS19, AP4S1, ARF3, ARF4, YIPF5, GOSR2, PERP	624	872	12782	1.3154845918607387	0.9999995989721538	0.19475314518091746	33.917206249151974
GOTERM_CC_FAT	GO:0016607~nuclear speck	11	1.3664596273291925	0.028426058648334772	SUMO1, DDX3X, MAGOH, NPM1, WBP11, CDC5L, SFRS1, PRPF18, PRPF40A, SFRS2, PNN	624	103	12782	2.1876089121234754	0.9999996347493167	0.1933145608049065	34.09065756463557
GOTERM_MF_FAT	GO:0005525~GTP binding	28	3.4782608695652173	0.028586708119297324	RAB9A, GNAI3, GLUD2, GLUD1, ARFRP1, HBS1L, EIF5, RHOQ, ARF6, RAB1A, TUBB, LANCL2, RALB, RAP2B, GTPBP4, DNM1L, RAP2C, RAN, RAB4A, DRG2, NOLC1, RRAS2, ARF3, RAB22A, ARF4, RAB5A, RAB14, RHEB	641	372	12983	1.524516464529549	0.9999999999973435	0.4070394915858824	36.44779127175077
SP_PIR_KEYWORDS	endosome	16	1.9875776397515528	0.02888004972372562	SCAMP1, CHMP5, ARF6, CD164, LAMP1, LAMP2, NPC1, CHMP1B, SCYL2, PTP4A1, VAMP7, RAB22A, PTP4A2, RAB5A, STEAP1, ATP6V0A2	802	209	19235	1.83607965731604	0.9999997291030556	0.18042344246915054	34.54956120623842
GOTERM_BP_FAT	GO:0051254~positive regulation of RNA metabolic process	35	4.3478260869565215	0.028965251042407415	ENY2, NCBP1, CNBP, ABLIM3, PRKDC, CASK, RHOQ, NFYB, FOXO3, NFYA, MED21, TCF7L2, NPAS2, ZNF148, TAF9, FOXO3B, RUNX1, MYC, FOSL1, RNF14, PLAGL2, BMP4, TBL1XR1, RAN, STRN3, CREB1, ILF3, PROX1, STAT3, GTF2H1, MED6, HHEX, ILF2, MED17, BMP7, SMARCA4	683	481	13528	1.4412385129808263	1.0	0.3402041746886175	40.961991884960504
GOTERM_BP_FAT	GO:0022403~cell cycle phase	31	3.8509316770186333	0.02923226635150024	POLA1, ANAPC10, CDC16, CCNG2, RPA1, TUBB, NUMA1, NIPBL, RANBP1, PAFAH1B1, PPP3CA, ZWILCH, CUL1, BUB3, STAG2, CDC6, MSH6, PDS5A, RAN, ILF3, CDC27, CDK2, SMC3, RAD1, CDKN1C, DCLRE1A, NOLC1, TOP3A, CLIP1, MAPRE1, KPNA2	683	414	13528	1.4831130066982126	1.0	0.34141925797403994	41.25238050638744
GOTERM_BP_FAT	GO:0009060~aerobic respiration	6	0.7453416149068323	0.029748934965309656	UQCRC2, SLC25A14, NNT, SDHC, IDH3A, FH	683	35	13528	3.3954402844593186	1.0	0.3449861918816488	41.81045052188935
GOTERM_BP_FAT	GO:0016126~sterol biosynthetic process	6	0.7453416149068323	0.029748934965309656	EBP, CNBP, SQLE, PRKAG2, PRKAA1, C14ORF1	683	35	13528	3.3954402844593186	1.0	0.3449861918816488	41.81045052188935
GOTERM_BP_FAT	GO:0005977~glycogen metabolic process	6	0.7453416149068323	0.029748934965309656	PPP1R2, PYGL, IL6ST, PRKAG2, PHKA1, GYG1	683	35	13528	3.3954402844593186	1.0	0.3449861918816488	41.81045052188935
GOTERM_MF_FAT	GO:0003743~translation initiation factor activity	8	0.9937888198757764	0.029749266938803327	EIF4B, EIF4E, EIF2S1, EIF5, EIF1, EIF2B3, GTF2B, EIF3M	641	61	12983	2.6563003503746705	0.9999999999991162	0.41359243887409014	37.62618550308861
KEGG_PATHWAY	hsa05120:Epithelial cell signaling in Helicobacter pylori infection	10	1.2422360248447204	0.029809332117710936	ATP6V1C1, ATP6V1A, TJP1, ADAM10, LYN, MET, MAP2K4, MAPK9, ATP6V1D, ATP6V0A2	330	68	5085	2.266042780748663	0.991616590552178	0.3077497375721713	30.554834210548222
BBID	74.CD47-IAP_with_avB3	3	0.37267080745341613	0.029948643999506454	PTK2, LYN, SYK	28	4	358	9.589285714285714	0.7813566089608588	0.7813566089608588	25.387000158311068
GOTERM_CC_FAT	GO:0030141~secretory granule	16	1.9875776397515528	0.029964080853514093	SCAMP1, SYT1, GNAI3, RAB4A, GAL, SPAG9, LAMP2, SYPL1, TMED2, DLD, RAB5A, RAB14, SLC30A5, HSPD1, PCSK5, ATP6V0A2	624	180	12782	1.8207977207977208	0.9999998382153253	0.20019370183634888	35.583011068414784
GOTERM_BP_FAT	GO:0010557~positive regulation of macromolecule biosynthetic process	45	5.590062111801243	0.0302594621150839	ENY2, CNBP, ABLIM3, PRKDC, CASK, RHOQ, EIF5A, NFYB, NFYA, FOXO3, MED21, TCF7L2, POT1, NPAS2, FNTA, ZNF148, TAF9, FOXO3B, RUNX1, FOSL1, MYC, RNF14, SYK, PLAGL2, BMP4, TBL1XR1, RAN, STRN3, CREB1, ILF3, DDX5, PROX1, STAT3, CDK2, GTF2H1, MED6, MAPK1, HHEX, MED7, YWHAH, ILF2, YAF2, MED17, UBC, BMP7, SMARCA4	683	654	13528	1.362848738028396	1.0	0.3484446707234008	42.356967400630474
GOTERM_BP_FAT	GO:0051168~nuclear export	8	0.9937888198757764	0.0305429301772404	HHEX, NCBP1, RAN, DDX19B, NPM1, EIF5A, GLE1, THOC2	683	60	13528	2.640897999023914	1.0	0.34974443635224295	42.65832228439523
GOTERM_BP_FAT	GO:0006144~purine base metabolic process	4	0.4968944099378882	0.030622104158824007	HPRT1, PAICS, GART, PRPS1	683	14	13528	5.65906714076553	1.0	0.3491384355869027	42.74222599479642
GOTERM_BP_FAT	GO:0046112~nucleobase biosynthetic process	4	0.4968944099378882	0.030622104158824007	HPRT1, PAICS, GART, PRPS1	683	14	13528	5.65906714076553	1.0	0.3491384355869027	42.74222599479642
SMART	SM00667:LisH	5	0.6211180124223602	0.03085576317363751	SMU1, TBL1XR1, RANBP9, NOLC1, PAFAH1B1	393	28	9079	4.125318066157761	0.9994756652784864	0.49675136961488575	33.28971537931964
GOTERM_CC_FAT	GO:0000125~PCAF complex	3	0.37267080745341613	0.03121484675677709	TAF12, TAF9, TRRAP	624	6	12782	10.24198717948718	0.9999999166468672	0.20513261928382087	36.77338287359786
GOTERM_CC_FAT	GO:0005664~nuclear origin of replication recognition complex	3	0.37267080745341613	0.03121484675677709	ORC2L, ORC3L, ORC5L	624	6	12782	10.24198717948718	0.9999999166468672	0.20513261928382087	36.77338287359786
GOTERM_BP_FAT	GO:0050778~positive regulation of immune response	14	1.7391304347826086	0.03147738297382657	LYN, IL6ST, POLR3C, MAP3K7, UBE2N, MAPK1, CD55, PSEN1, FYN, CD46, RIPK2, CD24, HSPD1, SYK	683	145	13528	1.9123744130862828	1.0	0.35566976607996537	43.64123864904613
UP_SEQ_FEATURE	repeat:ARM 5	5	0.6211180124223602	0.03162087474259741	PKP4, RAP1GDS1, KPNA4, KPNA2, KPNA1	802	29	19113	4.108908762576318	1.0	0.8998036261681075	42.71034414793289
SP_PIR_KEYWORDS	glycogen storage disease	4	0.4968944099378882	0.031629524053247274	LAMP2, PYGL, PRKAG2, PHKA1	802	17	19235	5.643244829103711	0.9999999372758684	0.19376770539292965	37.179369305531566
SP_PIR_KEYWORDS	proteinase	4	0.4968944099378882	0.031629524053247274	UQCRC2, PSMA2, PSMA5, PSMA3	802	17	19235	5.643244829103711	0.9999999372758684	0.19376770539292965	37.179369305531566
SP_PIR_KEYWORDS	methionine biosynthesis	3	0.37267080745341613	0.03163950667536863	MTHFD1, ENOPH1, MTRR	802	7	19235	10.278767367296046	0.9999999376086315	0.19159349138754456	37.18873562846912
UP_SEQ_FEATURE	binding site:ATP	33	4.099378881987578	0.03199997902448372	PRPF4B, NUAK1, MAPKAPK5, CASK, MAP3K7, MTHFS, PTK2, PRKAA1, TLK2, STK38L, SYK, CSNK1A1, SRPK2, LYN, ROCK1, MAT2A, BRAF, RYK, HKDC1, PDK3, MET, MAP2K4, CDK2, MAPK1, RPS6KA3, MAP4K5, RIOK3, FYN, MAPK9, RIPK2, PGK1, BMPR1A, PRPS1	802	542	19113	1.4510057881127438	1.0	0.8949733281207264	43.09792566319398
UP_SEQ_FEATURE	calcium-binding region:4	4	0.4968944099378882	0.032149409040847995	PDCD6, CALM1, RCN2, CALU	802	17	19113	5.607451958339445	1.0	0.8884721189023429	43.250017119781084
INTERPRO	IPR001452:Src homology-3 domain	17	2.111801242236025	0.032247770178062254	LYN, ABI2, ASAP1, CASK, ABI1, SKAP2, NEBL, DOCK4, TJP1, CTTN, SH3GLB1, FYN, NCK1, DLG3, SH3TC2, CRK, DLG1	753	213	16659	1.765725829078054	1.0	0.7969845577264734	41.62479014963005
GOTERM_BP_FAT	GO:0032582~negative regulation of gene-specific transcription	7	0.8695652173913043	0.032561319138446364	CDKN1C, HHEX, TBL1XR1, TAF9B, HDAC9, PROX1, SMARCA4	683	48	13528	2.888482186432406	1.0	0.3641400532638488	44.76145847232716
GOTERM_BP_FAT	GO:0008064~regulation of actin polymerization or depolymerization	8	0.9937888198757764	0.03306181666940895	ACTR3, ARPC1A, ARPC2, NCK1, SPTBN1, ARF6, ARPC5, DSTN	683	61	13528	2.5976045892038497	1.0	0.3672537004127734	45.27158395191707
GOTERM_BP_FAT	GO:0044042~glucan metabolic process	6	0.7453416149068323	0.03316436446651926	PPP1R2, PYGL, IL6ST, PRKAG2, PHKA1, GYG1	683	36	13528	3.3011224987798924	1.0	0.3668031992768541	45.37555388042903
GOTERM_BP_FAT	GO:0006073~cellular glucan metabolic process	6	0.7453416149068323	0.03316436446651926	PPP1R2, PYGL, IL6ST, PRKAG2, PHKA1, GYG1	683	36	13528	3.3011224987798924	1.0	0.3668031992768541	45.37555388042903
GOTERM_BP_FAT	GO:0006538~glutamate catabolic process	3	0.37267080745341613	0.033247223413345336	GLUD2, GLUD1, GAD1	683	6	13528	9.903367496339678	1.0	0.36618262933479706	45.459425658739924
GOTERM_CC_FAT	GO:0044432~endoplasmic reticulum part	26	3.229813664596273	0.03329864189919286	TUSC3, DERL1, RAB9A, DNAJC10, PDIA6, ALG6, FKBP1A, LMAN1, CALU, SSR1, PIGC, ASPH, DLG1, SPTLC1, SPTLC2, SLC33A1, AIFM1, SEC11A, ERLIN1, C14ORF147, MAGT1, SQLE, VAMP7, GOSR2, SPCS2, RCN2	624	347	12782	1.5348222862632084	0.9999999724414118	0.2147579124315756	38.71119168313994
GOTERM_CC_FAT	GO:0000776~kinetochore	9	1.1180124223602486	0.03341780360169373	SUMO3, SUMO2, ORC2L, NUP98, PSEN1, CLIP1, PAFAH1B1, ZWILCH, TPR, BUB3	624	77	12782	2.394230769230769	0.9999999741334292	0.21283655841877036	38.82031641592122
GOTERM_CC_FAT	GO:0000123~histone acetyltransferase complex	7	0.8695652173913043	0.03368220217244071	ENY2, ACTB, TAF12, TAF9B, MORF4, TAF9, TRRAP	624	50	12782	2.8677564102564106	0.9999999775265905	0.21178594406843942	39.06179922634274
GOTERM_CC_FAT	GO:0005856~cytoskeleton	83	10.31055900621118	0.0337045097121739	ENOX2, CEP76, PDLIM5, CASK, CBX3, RHOQ, CBX1, CDC16, DSTN, PNN, ACTR3, FNTB, RANBP9, CTTN, FNTA, BAG1, LOC100129652, CAMSAP1, SNTB1, RANBP1, MYC, STAG2, IFNGR1, KIF2A, DLG1, TBL1XR1, CDC6, ADAM10, LYN, ROCK1, DCTN4, ELMO2, ARPC1A, MAPK1, PSEN1, LYST, PSMA3, CLIP1, FLII, MAPRE1, DST, PARVA, YWHAZ, AKAP12, ABI2, ABI1, ARPC4, ARPC5, TPM4, STAU1, RPA1, TUBGCP4, TUBB, PTK2, NUMA1, GPHN, CEP57, ARPC2, KLC1, LANCL2, NPM1, NUDT21, PAFAH1B1, MYOF, CDC42EP3, STK38L, ACTB, TCP1, CEP192, C21ORF33, SMEK1, CDC27, SMC3, CORO1C, HNRNPH2, PTP4A1, SVIL, PSMD10, SPTBN1, MAP7, WDR1, HNRNPH1, CALM1	624	1381	12782	1.2311150411259029	0.9999999777916813	0.2094059483831313	39.08213270411854
GOTERM_CC_FAT	GO:0043596~nuclear replication fork	4	0.4968944099378882	0.03382584138177318	RPA1, PRIM1, POLA1, RPA4	624	15	12782	5.462393162393162	0.9999999791798113	0.2076310848024978	39.19261682011816
GOTERM_BP_FAT	GO:0000226~microtubule cytoskeleton organization	14	1.7391304347826086	0.03463992903214092	CAV2, CAV1, RAN, ARPC4, SMC3, TUBGCP4, TUBB, PTK2, RANBP9, NPM1, MAP7, RANBP1, PAFAH1B1, DST	683	147	13528	1.88635571358851	1.0	0.3770101341318296	46.851085560739726
GOTERM_BP_FAT	GO:0034654~nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process	17	2.111801242236025	0.03488019633109312	DCTD, NAMPT, MSH2, PRKAG2, CTPS2, HPRT1, ATP6V1D, GART, ATP6V1C1, MTHFD1, ATP6V1A, ATP5S, ADK, RRM1, PAICS, ATP6V0A2, PRPS1	683	193	13528	1.7446346884743476	1.0	0.3777168190737271	47.08775495624883
GOTERM_BP_FAT	GO:0034404~nucleobase, nucleoside and nucleotide biosynthetic process	17	2.111801242236025	0.03488019633109312	DCTD, NAMPT, MSH2, PRKAG2, CTPS2, HPRT1, ATP6V1D, GART, ATP6V1C1, MTHFD1, ATP6V1A, ATP5S, ADK, RRM1, PAICS, ATP6V0A2, PRPS1	683	193	13528	1.7446346884743476	1.0	0.3777168190737271	47.08775495624883
GOTERM_BP_FAT	GO:0001934~positive regulation of protein amino acid phosphorylation	10	1.2422360248447204	0.035047294003315514	BMP4, CAV1, PSEN1, LYN, IL6ST, PRKAG2, CD24, BMP7, BMPR1A, SYK	683	89	13528	2.225475841874085	1.0	0.3777895267651967	47.251763349984145
GOTERM_BP_FAT	GO:0032886~regulation of microtubule-based process	7	0.8695652173913043	0.03558489153934592	CAV2, CAV1, CEP76, NPM1, RANBP1, MAPRE1, DST	683	49	13528	2.829533570382765	1.0	0.3810172729715877	47.77617151080461
INTERPRO	IPR006594:LisH dimerisation motif	5	0.6211180124223602	0.03563981168778934	SMU1, TBL1XR1, RANBP9, NOLC1, PAFAH1B1	753	28	16659	3.950626067159932	1.0	0.8181181727042883	44.89545822244011
INTERPRO	IPR015609:Molecular chaperone, heat shock protein, Hsp40, DnaJ	6	0.7453416149068323	0.036206577411139106	DNAJC10, DNAJA1, DNAJB1, SEC63, DNAJB6, DNAJA2	753	41	16659	3.237586240404237	1.0	0.8125559327748098	45.4248703759927
UP_SEQ_FEATURE	repeat:TPR 7	7	0.8695652173913043	0.03648663962610157	RPAP3, STIP1, CDC16, OGT, SH3TC2, CDC27, GTF3C3	802	59	19113	2.827486368823703	1.0	0.9110213744212207	47.50118459811461
INTERPRO	IPR019586:Guanylate kinase-associated, C-terminal	3	0.37267080745341613	0.03674024172170192	TJP1, DLG3, DLG1	753	7	16659	9.481502561183836	1.0	0.8069102706919848	45.91899320019272
INTERPRO	IPR005937:26S proteasome subunit P45	3	0.37267080745341613	0.03674024172170192	PSMC6, PSMC3, PSMC2	753	7	16659	9.481502561183836	1.0	0.8069102706919848	45.91899320019272
GOTERM_BP_FAT	GO:0000097~sulfur amino acid biosynthetic process	4	0.4968944099378882	0.03687862601791332	MTHFD1, MAT2A, ENOPH1, MTRR	683	15	13528	5.281795998047828	1.0	0.3905372688011536	49.018060227069114
GOTERM_MF_FAT	GO:0005544~calcium-dependent phospholipid binding	5	0.6211180124223602	0.03689859265875457	ANXA7, ANXA3, RBM12, ANXA2P2, ANXA2	641	26	12983	3.8950558022320894	0.999999999999999	0.478950546691694	44.435074780662454
GOTERM_BP_FAT	GO:0042113~B cell activation	9	1.1180124223602486	0.037068709519345475	MSH6, SWAP70, MSH2, PRKDC, HSPD1, CD24, SKAP2, HDAC9, TPD52	683	76	13528	2.345534407027819	1.0	0.39074352398186196	49.19815928987057
GOTERM_BP_FAT	GO:0045321~leukocyte activation	20	2.484472049689441	0.03721744261495626	MSH6, YWHAZ, ADAM10, LYN, SWAP70, MSH2, PRKDC, FKBP1A, TPD52, SKAP2, HPRT1, PSEN1, FYN, VAMP7, NCK1, RIPK2, CD24, HSPD1, HDAC9, SYK	683	242	13528	1.6369202473288726	1.0	0.39060645679573147	49.338660840649084
UP_SEQ_FEATURE	repeat:ARM 9	4	0.4968944099378882	0.03740851753010943	PKP4, KPNA4, KPNA2, KPNA1	802	18	19113	5.295926849542809	1.0	0.9100657918464213	48.365229169995
UP_SEQ_FEATURE	domain:PI3K/PI4K	4	0.4968944099378882	0.03740851753010943	PRKDC, PIK3CA, ATR, TRRAP	802	18	19113	5.295926849542809	1.0	0.9100657918464213	48.365229169995
SP_PIR_KEYWORDS	blocked amino end	9	1.1180124223602486	0.0378554370098531	EIF4B, GNAI3, LYN, FYN, ARF3, ARF4, ARF6, PGK1, AMD1	802	92	19235	2.3462403773175757	0.9999999977508921	0.22280181822010492	42.77509498309557
GOTERM_BP_FAT	GO:0002252~immune effector process	13	1.6149068322981366	0.03806968179708596	MSH6, YWHAZ, LYN, MSH3, MSH2, SWAP70, PRKDC, TUBB, CD55, CD46, LYST, VAMP7, HSPD1	683	134	13528	1.9215489172002362	1.0	0.39623633946448533	50.13668511050622
SP_PIR_KEYWORDS	EF hand	7	0.8695652173913043	0.0381526341658127	GPD2, S100A4, MAPKAPK5, S100A10, CAPN2, CALM1, RCN2	802	60	19235	2.7981088944305896	0.9999999980823094	0.22190122491451258	43.03023606737132
SP_PIR_KEYWORDS	monomer	5	0.6211180124223602	0.03847879996229814	RPS6KA3, FYN, ARF4, RHEB, GAPDH	802	31	19235	3.8683533102727057	0.9999999983901926	0.22117182652345613	43.3090274748788
SP_PIR_KEYWORDS	phosphatidylinositol linkage	5	0.6211180124223602	0.03847879996229814	CD55, CD59, CD58, CD24, CAPRIN1	802	31	19235	3.8683533102727057	0.9999999983901926	0.22117182652345613	43.3090274748788
UP_SEQ_FEATURE	repeat:ARM 4	5	0.6211180124223602	0.03924765606530048	PKP4, RAP1GDS1, KPNA4, KPNA2, KPNA1	802	31	19113	3.8438178746681686	1.0	0.9143277820906838	50.04911266060592
GOTERM_BP_FAT	GO:0006351~transcription, DNA-dependent	23	2.857142857142857	0.03926592227860015	COPS2, POLR3K, POLR2K, CREB1, TAF9B, NFYA, STAT1, GTF2B, YBX1, GTF2H1, FUBP1, MSL3, MED7, MAX, TAF12, MED17, PIR, TAF9, MYC, FOSL1, GTF3C4, GTF3C3, NFX1	683	292	13528	1.5601195370946068	1.0	0.404535731151477	51.236824450252506
GOTERM_BP_FAT	GO:0000018~regulation of DNA recombination	5	0.6211180124223602	0.03959214845524099	MSH6, MSH3, MSH2, KPNA2, KPNA1	683	26	13528	3.8089874985921837	1.0	0.405761869397385	51.53284158946169
GOTERM_CC_FAT	GO:0005901~caveola	7	0.8695652173913043	0.039808029687060514	CAV2, CAV1, TUBB, LDLR, SLC2A1, LRP8, BMPR1A	624	52	12782	2.7574580867850096	0.999999999144839	0.23750958590422533	44.41436294294954
GOTERM_BP_FAT	GO:0045893~positive regulation of transcription, DNA-dependent	34	4.22360248447205	0.04003444109070296	ENY2, CNBP, ABLIM3, PRKDC, CASK, RHOQ, NFYB, FOXO3, NFYA, MED21, TCF7L2, NPAS2, ZNF148, TAF9, FOXO3B, RUNX1, MYC, FOSL1, RNF14, PLAGL2, BMP4, TBL1XR1, RAN, STRN3, CREB1, ILF3, PROX1, STAT3, GTF2H1, MED6, HHEX, ILF2, MED17, BMP7, SMARCA4	683	477	13528	1.4118008170882559	1.0	0.407894408435712	51.93146842319931
SMART	SM00146:PI3Kc	4	0.4968944099378882	0.040246857108477606	PRKDC, PIK3CA, ATR, TRRAP	393	18	9079	5.133729148996325	0.9999498293351916	0.5617679315913587	41.17354902352095
GOTERM_BP_FAT	GO:0006468~protein amino acid phosphorylation	45	5.590062111801243	0.04034772137097714	CAV2, PRPF4B, NUAK1, PTPLAD1, MAPKAPK5, PRKDC, CASK, ABI2, ABI1, MAP3K7, PTK2, PRKRA, PIK3CA, PRKAA1, TLK2, STK38L, SYK, CSNK1A1, SRPK2, ADAM10, LYN, ROCK1, BRAF, RYK, CREB1, PDK3, MAP2K4, MET, ATR, STAT1, CDK2, MAPK1, SPAG9, RPS6KA3, MAP4K5, PSEN1, RIOK3, FYN, SCYL2, EIF2S1, MAPK9, RIPK2, SPTBN1, BMP7, BMPR1A	683	667	13528	1.3362864687714708	1.0	0.4089883101193421	52.211944658503064
GOTERM_CC_FAT	GO:0005789~endoplasmic reticulum membrane	21	2.608695652173913	0.04043174803459951	SPTLC1, TUSC3, DERL1, RAB9A, SPTLC2, SLC33A1, SEC11A, ALG6, FKBP1A, ERLIN1, LMAN1, SSR1, C14ORF147, MAGT1, SQLE, VAMP7, PIGC, GOSR2, SPCS2, ASPH, DLG1	624	269	12782	1.5991206748641693	0.9999999993876532	0.23812349121350762	44.93406416644149
GOTERM_BP_FAT	GO:0007242~intracellular signaling cascade	78	9.68944099378882	0.040526365951330065	RAB9A, IL6ST, PRKAG2, RHOQ, RBM9, RAB1A, RGL1, MAP3K7, ANP32A, RALB, PIK3CA, TLK2, RAPGEF2, NET1, SYK, RAP2B, SRPK2, RAP2C, LYN, NUDT4, BRAF, ROCK1, SOCS2, AIFM1, RAN, RAB4A, RINT1, TANK, RAD1, MAPK1, SPAG9, MAP4K5, RFC4, PSEN1, MED17, UBR5, RRAS2, RAB5A, RAB14, MAPK9, RAD17, CAV1, CNIH, PTPLAD1, CREM, ARFRP1, ARF6, SOS2, DNAJA1, PRKAA1, STK38L, FEN1, RNF14, MSH6, GDI2, MSH2, NF1, MET, MAP2K4, BRIP1, RGS19, ATR, STAT1, YWHAE, STAT3, RPS6KA3, YWHAH, FYN, ARF3, ARF4, RAB22A, PRKAR1A, YWHAQ, PCNA, RHEB, APBB2, CRK, BCAR3	683	1256	13528	1.2300360903097052	1.0	0.40901792607916176	52.37119052862072
SP_PIR_KEYWORDS	redox-active disulfide	3	0.37267080745341613	0.04103845725702155	GSR, PDIA6, GLRX	802	8	19235	8.99392144638404	0.9999999995931685	0.23178874567727759	45.45322089619963
SP_PIR_KEYWORDS	carboxy-lyase	3	0.37267080745341613	0.04103845725702155	AMD1, GAD1, PAICS	802	8	19235	8.99392144638404	0.9999999995931685	0.23178874567727759	45.45322089619963
GOTERM_BP_FAT	GO:0001764~neuron migration	8	0.9937888198757764	0.04143599538960251	CAV2, PTK2, PSEN1, FYN, MET, PAFAH1B1, APBB2, YWHAE	683	64	13528	2.4758418740849195	1.0	0.41472223053855783	53.174303592337345
UP_SEQ_FEATURE	domain:Helicase ATP-binding	10	1.2422360248447204	0.041481280727789435	ATRX, DDX18, CHD1L, DDX3X, DDX19B, DHX15, BRIP1, SKIV2L2, DDX5, SMARCA4	802	110	19113	2.166515529358422	1.0	0.9201694609992835	52.02460875595576
UP_SEQ_FEATURE	domain:IBB	3	0.37267080745341613	0.041519553165746306	KPNA4, KPNA2, KPNA1	802	8	19113	8.93687655860349	1.0	0.9147226998055448	52.05780769369306
KEGG_PATHWAY	hsa04666:Fc gamma R-mediated phagocytosis	12	1.4906832298136645	0.041666821155397916	ARPC1A, MAPK1, DNM1L, LYN, ARPC2, ASAP1, PIK3CA, ARF6, ARPC4, ARPC5, CRK, SYK	330	95	5085	1.9464114832535884	0.9987988124044961	0.38141302079315886	40.11833374529247
GOTERM_MF_FAT	GO:0003727~single-stranded RNA binding	5	0.6211180124223602	0.04168496494934009	HNRPDL, CNBP, PTBP1, SYNCRIP, HNRNPH1	641	27	12983	3.750794476223493	1.0	0.5154945206574285	48.597670616591074
GOTERM_CC_FAT	GO:0042589~zymogen granule membrane	3	0.37267080745341613	0.04230873270537411	SCAMP1, TMED2, RAB5A	624	7	12782	8.778846153846155	0.9999999997761686	0.2451735640948085	46.47086949238282
GOTERM_CC_FAT	GO:0005832~chaperonin-containing T-complex	3	0.37267080745341613	0.04230873270537411	CCT5, TCP1, CCT2	624	7	12782	8.778846153846155	0.9999999997761686	0.2451735640948085	46.47086949238282
GOTERM_CC_FAT	GO:0032300~mismatch repair complex	3	0.37267080745341613	0.04230873270537411	MSH6, MSH3, MSH2	624	7	12782	8.778846153846155	0.9999999997761686	0.2451735640948085	46.47086949238282
GOTERM_MF_FAT	GO:0031405~lipoic acid binding	3	0.37267080745341613	0.04319766559355197	DLD, GCSH, DLAT	641	7	12983	8.680410073545799	1.0	0.5218580649994582	49.85129339992862
KEGG_PATHWAY	hsa05210:Colorectal cancer	11	1.3664596273291925	0.043231690414977805	MAPK1, MSH6, MSH3, BRAF, MSH2, MET, SOS2, MAPK9, PIK3CA, MYC, TCF7L2	330	84	5085	2.017857142857143	0.9990721632706057	0.372185362052729	41.285922625678374
UP_SEQ_FEATURE	compositionally biased region:Asp-rich	5	0.6211180124223602	0.04342007051560432	EIF4B, POLA1, ATAD2, WBP11, C11ORF58	802	32	19113	3.723698566084788	1.0	0.9186712481563747	53.67942591488388
GOTERM_BP_FAT	GO:0030900~forebrain development	14	1.7391304347826086	0.043530763794904545	BMP4, CREB1, NF1, HPRT1, YWHAE, APLP2, ATRX, HHEX, DKK1, PSEN1, FYN, PAFAH1B1, LRP8, SMARCA4	683	152	13528	1.8243045387994143	1.0	0.42930504723158824	54.975419770315845
GOTERM_BP_FAT	GO:0001959~regulation of cytokine-mediated signaling pathway	4	0.4968944099378882	0.04373494684223397	HSP90AB1, CAV1, IL6ST, CD24	683	16	13528	4.951683748169839	1.0	0.42944213779174945	55.14743655783219
GOTERM_BP_FAT	GO:0031124~mRNA 3'-end processing	4	0.4968944099378882	0.04373494684223397	PAPOLA, CSTF2, GRSF1, SLBP	683	16	13528	4.951683748169839	1.0	0.42944213779174945	55.14743655783219
SP_PIR_KEYWORDS	pyridoxal phosphate	7	0.8695652173913043	0.04374065541113191	SPTLC1, SPTLC2, PYGL, SRR, PROSC, PSAT1, GAD1	802	62	19235	2.7078473171908937	0.9999999999051457	0.24274586722973202	47.6347390270771
SMART	SM00160:RanBD	3	0.37267080745341613	0.043808834259245845	NUP50, RANBP1, RANBP2	393	8	9079	8.663167938931297	0.9999795223936778	0.5641579100559568	43.931920147812285
GOTERM_BP_FAT	GO:0045910~negative regulation of DNA recombination	3	0.37267080745341613	0.04501307389171619	MSH6, MSH3, MSH2	683	7	13528	8.488600711148294	1.0	0.43753213822953807	56.21019302267691
GOTERM_BP_FAT	GO:0043243~positive regulation of protein complex disassembly	3	0.37267080745341613	0.04501307389171619	MGEA5, EIF5A, DSTN	683	7	13528	8.488600711148294	1.0	0.43753213822953807	56.21019302267691
INTERPRO	IPR000403:Phosphatidylinositol 3- and 4-kinase, catalytic	4	0.4968944099378882	0.04508098851986435	PRKDC, PIK3CA, ATR, TRRAP	753	18	16659	4.916334661354581	1.0	0.8596133373071311	53.11614712930722
INTERPRO	IPR018936:Phosphatidylinositol 3- and 4-kinase, conserved site	4	0.4968944099378882	0.04508098851986435	PRKDC, PIK3CA, ATR, TRRAP	753	18	16659	4.916334661354581	1.0	0.8596133373071311	53.11614712930722
GOTERM_MF_FAT	GO:0003678~DNA helicase activity	6	0.7453416149068323	0.045392678412307416	ATRX, XRCC5, MCM7, CHD1L, BRIP1, MCM4	641	40	12983	3.03814352574103	1.0	0.5334374063314995	51.61956285787568
GOTERM_BP_FAT	GO:0006732~coenzyme metabolic process	14	1.7391304347826086	0.04548428468656694	NAMPT, ACLY, DLAT, IDH3A, SOD2, MTHFD1, ACOT9, GSR, MTHFS, GPHN, NNT, SDHC, DLD, FH	683	153	13528	1.8123809797222943	1.0	0.4395865821200925	56.59596883948637
SMART	SM00487:DEXDc	10	1.2422360248447204	0.04566944609160848	ATRX, DDX18, CHD1L, DDX3X, DDX19B, DHX15, BRIP1, SKIV2L2, DDX5, SMARCA4	393	109	9079	2.1194294651819687	0.9999871938773668	0.5527711281780185	45.32484057829562
GOTERM_BP_FAT	GO:0006997~nucleus organization	7	0.8695652173913043	0.04571320063580455	NUMA1, NUP98, TMEM48, AIFM1, PAFAH1B1, CD24, MYC	683	52	13528	2.6662912490145287	1.0	0.439858629425122	56.78221988061614
GOTERM_BP_FAT	GO:0031570~DNA integrity checkpoint	7	0.8695652173913043	0.04571320063580455	RAD1, CDC6, MSH2, RINT1, BRIP1, ATR, RAD17	683	52	13528	2.6662912490145287	1.0	0.439858629425122	56.78221988061614
GOTERM_BP_FAT	GO:0009064~glutamine family amino acid metabolic process	7	0.8695652173913043	0.04571320063580455	ALDH18A1, GLUD2, GLUD1, GLS, GGH, CTPS2, GAD1	683	52	13528	2.6662912490145287	1.0	0.439858629425122	56.78221988061614
KEGG_PATHWAY	hsa00020:Citrate cycle (TCA cycle)	6	0.7453416149068323	0.046591625898938456	SDHC, DLD, ACLY, DLAT, IDH3A, FH	330	31	5085	2.9824046920821115	0.9994677985894733	0.37571952617637316	43.7226492825724
GOTERM_BP_FAT	GO:0010551~regulation of specific transcription from RNA polymerase II promoter	10	1.2422360248447204	0.04716005391591702	HHEX, TBL1XR1, CREB1, TAF9B, PRKDC, RHOQ, TAF9, HDAC9, TCF7L2, SMARCA4	683	94	13528	2.1070994673063144	1.0	0.44888006272022896	57.94206676539388
COG_ONTOLOGY	DNA replication, recombination, and repair	8	0.9937888198757764	0.0473493087887886	NBPF14, PRIM1, MSH6, MSH3, MSH2, TOP3A, SKIV2L2, DST	92	72	1950	2.3550724637681157	0.6209698668128583	0.38434576815623056	30.870087770400257
INTERPRO	IPR002652:Importin-alpha-like, importin-beta-binding region	3	0.37267080745341613	0.047544987672184236	KPNA4, KPNA2, KPNA1	753	8	16659	8.296314741035857	1.0	0.8660774693046613	55.063690018086085
INTERPRO	IPR004099:Pyridine nucleotide-disulphide oxidoreductase, dimerisation	3	0.37267080745341613	0.047544987672184236	GSR, AIFM1, DLD	753	8	16659	8.296314741035857	1.0	0.8660774693046613	55.063690018086085
INTERPRO	IPR013720:LisH dimerisation motif, subgroup	3	0.37267080745341613	0.047544987672184236	TBL1XR1, RANBP9, PAFAH1B1	753	8	16659	8.296314741035857	1.0	0.8660774693046613	55.063690018086085
INTERPRO	IPR000156:Ran Binding Protein 1	3	0.37267080745341613	0.047544987672184236	NUP50, RANBP1, RANBP2	753	8	16659	8.296314741035857	1.0	0.8660774693046613	55.063690018086085
BBID	11.IL-6_gp130-Jak-STAT	3	0.37267080745341613	0.04759691155540957	IL6ST, STAT1, STAT3	28	5	358	7.671428571428572	0.9126948720656142	0.7045255883593542	37.48068203399282
GOTERM_BP_FAT	GO:0043408~regulation of MAPKKK cascade	11	1.3664596273291925	0.04817882234888722	MAP3K7, CAV1, MAP4K5, AIDA, ATP6AP2, PTPLAD1, NF1, RIPK2, CD24, PDCD4, SYK	683	109	13528	1.9988448157749807	1.0	0.45469232224432987	58.74104435293097
KEGG_PATHWAY	hsa04150:mTOR signaling pathway	8	0.9937888198757764	0.048339944528475565	EIF4B, MAPK1, RPS6KA3, EIF4E, BRAF, RHEB, PIK3CA, PRKAA1	330	52	5085	2.3706293706293704	0.9996017728643215	0.3690314728755022	44.953566666754355
SP_PIR_KEYWORDS	threonine protease	4	0.4968944099378882	0.048382038602105604	PSMA2, PSMA1, PSMA5, PSMA3	802	20	19235	4.796758104738155	0.9999999999922959	0.2626069901536239	51.19328643249522
GOTERM_MF_FAT	GO:0002039~p53 binding	4	0.4968944099378882	0.048401698507507016	TAF9, PSME3, HSPD1, SMARCA4	641	17	12983	4.765715334495733	1.0	0.5506212942253745	53.9488957991265
GOTERM_BP_FAT	GO:0019220~regulation of phosphate metabolic process	34	4.22360248447205	0.04845479513880089	CAV1, IL6ST, PTPLAD1, PRKAG2, FKBP1A, PRDX3, PDCD4, APLP2, CCNE2, MAP3K7, MCM7, NPM1, PRKAA1, CD24, AGK, SYK, BMP4, CDC6, GTPBP4, LYN, NF1, MET, YWHAE, GTF2H1, CDKN1C, SPAG9, MAP4K5, PPP1R2, PSEN1, PRKAR1A, LRP8, BMP7, RAD17, BMPR1A	683	485	13528	1.3885133809300994	1.0	0.4552246347019071	58.95499848219422
GOTERM_BP_FAT	GO:0051174~regulation of phosphorus metabolic process	34	4.22360248447205	0.04845479513880089	CAV1, IL6ST, PTPLAD1, PRKAG2, FKBP1A, PRDX3, PDCD4, APLP2, CCNE2, MAP3K7, MCM7, NPM1, PRKAA1, CD24, AGK, SYK, BMP4, CDC6, GTPBP4, LYN, NF1, MET, YWHAE, GTF2H1, CDKN1C, SPAG9, MAP4K5, PPP1R2, PSEN1, PRKAR1A, LRP8, BMP7, RAD17, BMPR1A	683	485	13528	1.3885133809300994	1.0	0.4552246347019071	58.95499848219422
GOTERM_BP_FAT	GO:0044264~cellular polysaccharide metabolic process	7	0.8695652173913043	0.049448669977171344	PPP1R2, PYGL, IL6ST, PRKAG2, PHKA1, GYG1, B3GNT2	683	53	13528	2.6159838669576505	1.0	0.4607330266384929	59.716874509554216
PIR_SUPERFAMILY	PIRSF005673:pendulin	3	0.37267080745341613	0.049515649999983306	KPNA4, KPNA2, KPNA1	394	7	7396	8.044960116026106	0.9999999999123188	0.9995557417389279	51.41369287225316
KEGG_PATHWAY	hsa04914:Progesterone-mediated oocyte maturation	11	1.3664596273291925	0.049532524648568915	HSP90AB1, MAPK1, RPS6KA3, GNAI3, BRAF, MAPK9, PIK3CA, ANAPC10, CDC16, CDC27, CDK2	330	86	5085	1.9709302325581395	0.9996733466705611	0.3597668288853948	45.77899431470486
PIR_SUPERFAMILY	PIRSF037165:ras protein	4	0.4968944099378882	0.04978867317167062	RAP2B, RAP2C, RRAS2, RALB	394	16	7396	4.692893401015228	0.9999999999230847	0.9970385585739993	51.61168825347271
GOTERM_BP_FAT	GO:0000387~spliceosomal snRNP biogenesis	5	0.6211180124223602	0.05013631524378328	NCBP1, PRMT5, SNRPD1, SIP1, GEMIN4	683	28	13528	3.5369169629784563	1.0	0.46405576500366974	60.236166745290944
GOTERM_BP_FAT	GO:0008156~negative regulation of DNA replication	5	0.6211180124223602	0.05013631524378328	CDC6, GTPBP4, ATR, POT1, RAD17	683	28	13528	3.5369169629784563	1.0	0.46405576500366974	60.236166745290944
GOTERM_MF_FAT	GO:0016563~transcription activator activity	29	3.602484472049689	0.05042459731610083	ENY2, CREM, TRRAP, FOXO3, NFYA, MED21, MAX, ZNF148, NPM1, HNRNPD, TAF9, FOXO3B, RUNX1, FOSL1, RNF14, TFDP1, TBL1XR1, SUB1, RAN, ILF3, STAT3, CDKN1C, MED6, MED7, YWHAH, TAF12, YAF2, PSMC3, MED17, SMARCA4	641	410	12983	1.4326205243331684	1.0	0.559487628194587	55.45538853917441
BIOCARTA	h_fbw7Pathway:Cyclin E Destruction Pathway	4	0.4968944099378882	0.0508435331202385	SKP1, CDK2, CUL1, TFDP1	143	9	1437	4.466200466200466	0.9999690810739407	0.9999690810739407	47.97811620657374
BIOCARTA	h_eifPathway:Eukaryotic protein translation	4	0.4968944099378882	0.0508435331202385	EIF4E, EIF2S1, EIF5, EIF1	143	9	1437	4.466200466200466	0.9999690810739407	0.9999690810739407	47.97811620657374
GOTERM_BP_FAT	GO:0010629~negative regulation of gene expression	35	4.3478260869565215	0.051087115137115696	EID1, COPS2, TH1L, TAF9B, CBX3, BCL2L1, RBM9, TCEAL1, PDCD4, SUMO1, ORC2L, ZNF148, LANCL2, PRKRA, MYC, ENO1, NFX1, NKRF, BMP4, TBL1XR1, STRN3, ILF3, SNW1, PROX1, STAT3, CDKN1C, HHEX, TRIM33, YAF2, DR1, NAB1, YWHAQ, HDAC9, DNAJB6, SMARCA4	683	504	13528	1.3754677078249553	1.0	0.4691143890726044	60.94378234956683
SP_PIR_KEYWORDS	signalosome	3	0.37267080745341613	0.05133373317609874	COPS2, COPS3, COPS8	802	9	19235	7.9945968412302575	0.9999999999984492	0.27378497952634784	53.33783478663956
INTERPRO	IPR001353:Proteasome, subunit alpha/beta	4	0.4968944099378882	0.05179335376431661	PSMA2, PSMA1, PSMA5, PSMA3	753	19	16659	4.657580205493813	1.0	0.8812151220267362	58.2443049578089
GOTERM_BP_FAT	GO:0007010~cytoskeleton organization	31	3.8509316770186333	0.05191756565937469	CAV2, CAV1, ABLIM3, RHOQ, ABI2, ARF6, ARPC4, ARPC5, DSTN, TUBGCP4, RANBP9, PTK2, TUBB, LOC100129652, NPM1, RANBP1, PAFAH1B1, DLG1, ROCK1, RAN, NF1, PROX1, SMC3, ARPC1A, NCK1, SVIL, MAP7, CRK, DST, DNAJB6, PARVA	683	436	13528	1.4082770292960092	1.0	0.4732866145622461	61.55208614872887
SP_PIR_KEYWORDS	autophosphorylation	6	0.7453416149068323	0.05223632500163643	BRAF, LYN, FYN, MET, PHKA1, SYK	802	49	19235	2.9367906763702987	0.9999999999990511	0.27522975274261463	53.9758882717882
GOTERM_MF_FAT	GO:0008135~translation factor activity, nucleic acid binding	10	1.2422360248447204	0.052263022360016884	EIF4B, EIF4E, EIF2S1, HBS1L, EIF5, EIF5A, EIF1, EIF2B3, GTF2B, EIF3M	641	98	12983	2.0667643032251903	1.0	0.5666056437477509	56.784369405417024
GOTERM_BP_FAT	GO:0030833~regulation of actin filament polymerization	7	0.8695652173913043	0.05336633296495352	ACTR3, ARPC1A, ARPC2, NCK1, SPTBN1, ARF6, ARPC5	683	54	13528	2.56753972127325	1.0	0.48146707981982406	62.591944522705525
UP_SEQ_FEATURE	domain:J	6	0.7453416149068323	0.0534139022639876	DNAJC10, DNAJA1, DNAJB1, SEC63, DNAJB6, DNAJA2	802	49	19113	2.9181637742378745	1.0	0.9513623186981648	61.39001613281012
SP_PIR_KEYWORDS	actin-binding	17	2.111801242236025	0.053790563754604656	ARPC4, ARPC5, TPM4, DSTN, NEBL, ARPC1A, ACTR3, CORO1C, ARPC2, SVIL, SNTB1, SPTBN1, FLII, WDR1, STK38L, DST, PARVA	802	247	19235	1.6507062303754783	0.9999999999995931	0.27959005594025865	55.05560191742105
GOTERM_BP_FAT	GO:0050818~regulation of coagulation	6	0.7453416149068323	0.053801248520283514	CAV1, PSEN1, F2RL1, PLAU, ANXA2P2, ANXA2	683	41	13528	2.89854658429454	1.0	0.48289958881035766	62.89888707814421
GOTERM_CC_FAT	GO:0019866~organelle inner membrane	24	2.981366459627329	0.05385707259582459	UQCRC2, HCCS, GPD2, ALDH18A1, LYN, TIMM17A, AK2, CBX3, TIMM23, VDAC3, SOD2, TIMM8A, PPIF, SLC25A14, NNT, PSEN1, ATP5S, SDHC, NDUFV2, SLC25A46, PCNA, TOMM22, HSPD1, MATR3	624	329	12782	1.4942716857610476	0.9999999999995617	0.29931616015823026	55.081731023810974
UP_SEQ_FEATURE	topological domain:Lumenal	27	3.354037267080745	0.0543009640797785	DERL1, CNIH, LMAN1, CANX, UXS1, SEC63, SSR1, TMED2, BCAP29, B3GNT2, ASPH, B4GALT4, SCAMP1, C1GALT1C1, GDE1, SEC11A, TOR1AIP1, ERLIN1, MGAT2, LAMP1, C14ORF147, LAMP2, PSEN1, YIPF5, SPCS2, ATP6V0A2, SEL1L	802	444	19113	1.449223225719485	1.0	0.950119222260524	62.01250846535008
GOTERM_CC_FAT	GO:0000808~origin recognition complex	3	0.37267080745341613	0.0546224395387419	ORC2L, ORC3L, ORC5L	624	8	12782	7.681490384615385	0.9999999999997109	0.2998372552073737	55.604165177685246
GOTERM_BP_FAT	GO:0001932~regulation of protein amino acid phosphorylation	15	1.8633540372670807	0.054663093012669674	BMP4, CAV1, LYN, IL6ST, PTPLAD1, PRKAG2, FKBP1A, PDCD4, MAP4K5, PSEN1, PRKAR1A, CD24, BMP7, SYK, BMPR1A	683	173	13528	1.7173469646831812	1.0	0.4870755977552924	63.500123747501355
SMART	SM00271:DnaJ	6	0.7453416149068323	0.054821234079267464	DNAJC10, DNAJA1, DNAJB1, SEC63, DNAJB6, DNAJA2	393	48	9079	2.8877226463104324	0.9999987443648042	0.5958050355209705	51.72322529213263
GOTERM_BP_FAT	GO:0051129~negative regulation of cellular component organization	13	1.6149068322981366	0.05502457519327693	RHOQ, ARF6, TTC3, POT1, PTK2, SET, YWHAH, PSEN1, NPM1, SPTBN1, MAPRE1, SEMA3A, TPR	683	142	13528	1.8132926401748706	1.0	0.4879916225822285	63.74955084416977
GOTERM_BP_FAT	GO:0060284~regulation of cell development	17	2.111801242236025	0.05509852476820519	BMP4, XRCC5, LYN, HOXA11, NF1, PROX1, TTC3, ACTR3, PTK2, YWHAH, PSEN1, UBC, SEMA3A, CD24, HDAC9, BMP7, BMPR1A	683	205	13528	1.6425097311002392	1.0	0.4870638180721526	63.800378253100774
GOTERM_BP_FAT	GO:0010035~response to inorganic substance	17	2.111801242236025	0.05509852476820519	ACTB, SYT1, CAV1, GGH, PRDX3, BCL2L1, STAT1, SOD2, GART, NPC1, FNTA, DDX19B, SLC30A5, MAPK9, PDCD6, FOSL1, CALM1	683	205	13528	1.6425097311002392	1.0	0.4870638180721526	63.800378253100774
GOTERM_BP_FAT	GO:0042327~positive regulation of phosphorylation	10	1.2422360248447204	0.05561924777077504	BMP4, CAV1, PSEN1, LYN, IL6ST, PRKAG2, CD24, BMP7, BMPR1A, SYK	683	97	13528	2.041931442544264	1.0	0.48898533011974	64.15638373502118
GOTERM_BP_FAT	GO:0043393~regulation of protein binding	5	0.6211180124223602	0.05593023021232203	GTPBP4, AIDA, PSEN1, FKBP1A, ATR	683	29	13528	3.4149543090826473	1.0	0.48956253898503155	64.36741535023074
GOTERM_BP_FAT	GO:0070646~protein modification by small protein removal	5	0.6211180124223602	0.05593023021232203	ENY2, WDR48, SENP2, USP1, TRRAP	683	29	13528	3.4149543090826473	1.0	0.48956253898503155	64.36741535023074
GOTERM_MF_FAT	GO:0008320~protein transmembrane transporter activity	4	0.4968944099378882	0.056022922192331716	MCL1, TIMM17A, TOMM22, TIMM23	641	18	12983	4.500953371468192	1.0	0.5864834888872008	59.387630254088265
GOTERM_MF_FAT	GO:0015036~disulfide oxidoreductase activity	4	0.4968944099378882	0.056022922192331716	GLRX3, GSR, ENOX2, GLRX	641	18	12983	4.500953371468192	1.0	0.5864834888872008	59.387630254088265
GOTERM_BP_FAT	GO:0002684~positive regulation of immune system process	19	2.360248447204969	0.05638969442640924	ADAM10, LYN, IL6ST, F2RL1, POLR3C, UBE2N, MAP3K7, MAPK1, CD55, PSEN1, FYN, CD46, NCK1, RIPK2, CD24, HSPD1, IL13RA1, AP3B1, SYK	683	238	13528	1.5812099363903687	1.0	0.49106780671980843	64.67706017630105
GOTERM_CC_FAT	GO:0044438~microbody part	6	0.7453416149068323	0.05668799586180695	ACOX1, ACSL1, PEX1, AGPS, IDE, PEX3	624	43	12782	2.858228980322004	0.9999999999999061	0.30636278568031106	56.98600755700003
GOTERM_CC_FAT	GO:0044439~peroxisomal part	6	0.7453416149068323	0.05668799586180695	ACOX1, ACSL1, PEX1, AGPS, IDE, PEX3	624	43	12782	2.858228980322004	0.9999999999999061	0.30636278568031106	56.98600755700003
GOTERM_BP_FAT	GO:0032535~regulation of cellular component size	21	2.608695652173913	0.05669040387400573	ADAM10, CGRRF1, ENOX2, CREB1, TAF9B, ARF6, ARPC5, DDX5, DSTN, NEBL, ARPC1A, ACTR3, ARPC2, NCK1, NPM1, SPTBN1, TAF9, SEMA3A, APBB2, EMP1, ENO1	683	271	13528	1.534839242975153	1.0	0.4915671239404804	64.87833859249434
GOTERM_BP_FAT	GO:0045944~positive regulation of transcription from RNA polymerase II promoter	27	3.354037267080745	0.05684195261105042	CNBP, ABLIM3, PRKDC, CASK, RHOQ, FOXO3, NFYA, MED21, TCF7L2, NPAS2, ZNF148, TAF9, FOXO3B, RUNX1, MYC, FOSL1, PLAGL2, BMP4, TBL1XR1, STRN3, CREB1, STAT3, GTF2H1, MED6, HHEX, MED17, BMP7, SMARCA4	683	371	13528	1.4414604981195218	1.0	0.4911343032682409	64.97936611353165
GOTERM_BP_FAT	GO:0006916~anti-apoptosis	17	2.111801242236025	0.0570871624854863	YWHAZ, BRAF, SOCS2, MCL1, BCL2L1, HBXIP, TCF7L2, SOD2, PSEN1, BAG1, SH3GLB1, NPM1, UBC, RIPK2, PIK3CA, MYC, API5	683	206	13528	1.6345363828910149	1.0	0.49128603224881096	65.14225035575116
INTERPRO	IPR014001:DEAD-like helicase, N-terminal	10	1.2422360248447204	0.058003560877138795	ATRX, DDX18, CHD1L, DDX3X, DDX19B, DHX15, BRIP1, SKIV2L2, DDX5, SMARCA4	753	109	16659	2.029679447348222	1.0	0.9022435252044998	62.515345012629155
GOTERM_BP_FAT	GO:0006465~signal peptide processing	3	0.37267080745341613	0.05804954804382935	SEC11A, SPCS2, PCSK5	683	8	13528	7.427525622254758	1.0	0.4958503898304051	65.77464193115483
GOTERM_BP_FAT	GO:0043094~cellular metabolic compound salvage	3	0.37267080745341613	0.05804954804382935	ADK, ENOPH1, HPRT1	683	8	13528	7.427525622254758	1.0	0.4958503898304051	65.77464193115483
GOTERM_BP_FAT	GO:0046605~regulation of centrosome cycle	3	0.37267080745341613	0.05804954804382935	CEP76, NPM1, RANBP1	683	8	13528	7.427525622254758	1.0	0.4958503898304051	65.77464193115483
GOTERM_BP_FAT	GO:0006301~postreplication repair	3	0.37267080745341613	0.05804954804382935	UBE2N, UBE2A, MSH2	683	8	13528	7.427525622254758	1.0	0.4958503898304051	65.77464193115483
GOTERM_BP_FAT	GO:0070302~regulation of stress-activated protein kinase signaling pathway	8	0.9937888198757764	0.05823017944398206	MAP3K7, MAP4K5, AIDA, LYN, PTPLAD1, RIPK2, PDCD4, SYK	683	69	13528	2.2964330426294906	1.0	0.49558848157152324	65.89212234234859
COG_ONTOLOGY	Energy production and conversion	5	0.6211180124223602	0.05874167877642613	GPD2, PRUNE, AGPS, ACLY, ETFA	92	32	1950	3.311820652173913	0.7020272340119218	0.33207834504037104	36.91878722757227
GOTERM_MF_FAT	GO:0019205~nucleobase, nucleoside, nucleotide kinase activity	6	0.7453416149068323	0.058972516086611	ADK, CASK, DLG3, AK2, TAF9, DLG1	641	43	12983	2.826180023945144	1.0	0.5997755468648435	61.32631546756569
GOTERM_MF_FAT	GO:0034062~RNA polymerase activity	6	0.7453416149068323	0.058972516086611	PRIM1, POLR3K, POLR2K, POLA1, POLR3C, MED21	641	43	12983	2.826180023945144	1.0	0.5997755468648435	61.32631546756569
GOTERM_MF_FAT	GO:0003899~DNA-directed RNA polymerase activity	6	0.7453416149068323	0.058972516086611	PRIM1, POLR3K, POLR2K, POLA1, POLR3C, MED21	641	43	12983	2.826180023945144	1.0	0.5997755468648435	61.32631546756569
GOTERM_BP_FAT	GO:0032940~secretion by cell	17	2.111801242236025	0.059124751366431874	SCAMP1, SYT1, CYB5R4, YWHAZ, LYN, LIN7C, VTI1B, GAL, CANX, ARFGEF1, PSEN1, VAMP7, RAB14, VAMP3, EXOC5, PCSK5, SYK	683	207	13528	1.6266400718625558	1.0	0.49965949436566404	66.46834982404874
GOTERM_BP_FAT	GO:0032508~DNA duplex unwinding	4	0.4968944099378882	0.05918741660435478	MCM7, TOP3A, MCM4, POT1	683	18	13528	4.401496665039857	1.0	0.4986769936553588	66.50836841708366
GOTERM_BP_FAT	GO:0032392~DNA geometric change	4	0.4968944099378882	0.05918741660435478	MCM7, TOP3A, MCM4, POT1	683	18	13528	4.401496665039857	1.0	0.4986769936553588	66.50836841708366
INTERPRO	IPR001327:Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region	3	0.37267080745341613	0.05933707328556015	GSR, AIFM1, DLD	753	9	16659	7.374501992031872	1.0	0.9011627334174149	63.3772837269727
INTERPRO	IPR002939:Chaperone DnaJ, C-terminal	3	0.37267080745341613	0.05933707328556015	DNAJA1, DNAJB1, DNAJA2	753	9	16659	7.374501992031872	1.0	0.9011627334174149	63.3772837269727
GOTERM_BP_FAT	GO:0070647~protein modification by small protein conjugation or removal	14	1.7391304347826086	0.06088237819182085	ENY2, UBE2A, USP1, UBE2H, TRRAP, SENP2, WDR48, SUMO3, UBE2N, SUMO2, SUMO1, UBE2D3, TRIM33, UBC, RNF14	683	160	13528	1.7330893118594437	1.0	0.5074384465895916	67.57383581366211
SP_PIR_KEYWORDS	decarboxylase	4	0.4968944099378882	0.061507327470651144	AMD1, GAD1, PAICS, UXS1	802	22	19235	4.360689186125595	0.999999999999994	0.31080083692660343	60.07588345463344
SP_PIR_KEYWORDS	phospholipid binding	4	0.4968944099378882	0.061507327470651144	ANXA7, SYT1, ANXA3, ANXA2	802	22	19235	4.360689186125595	0.999999999999994	0.31080083692660343	60.07588345463344
GOTERM_BP_FAT	GO:0010564~regulation of cell cycle process	11	1.3664596273291925	0.06177337725497991	CAV2, CEP76, PRMT5, NPM1, RANBP1, ANAPC10, CDC16, APBB2, TPR, PROX1, SMARCA4	683	114	13528	1.9111761835041485	1.0	0.5113162370126645	68.12101015933652
GOTERM_BP_FAT	GO:0002449~lymphocyte mediated immunity	8	0.9937888198757764	0.062026552396341805	MSH6, CD55, TUBB, SWAP70, MSH2, LYST, CD46, HSPD1	683	70	13528	2.263626856306212	1.0	0.5114352419241371	68.27489053480296
GOTERM_CC_FAT	GO:0005778~peroxisomal membrane	5	0.6211180124223602	0.06203428952339886	ACOX1, ACSL1, PEX1, AGPS, PEX3	624	31	12782	3.303866832092638	0.9999999999999949	0.32739479680656736	60.37896792872439
GOTERM_CC_FAT	GO:0031903~microbody membrane	5	0.6211180124223602	0.06203428952339886	ACOX1, ACSL1, PEX1, AGPS, PEX3	624	31	12782	3.303866832092638	0.9999999999999949	0.32739479680656736	60.37896792872439
GOTERM_BP_FAT	GO:0033044~regulation of chromosome organization	5	0.6211180124223602	0.062068091510495416	UBE2N, SET, TLK2, MYC, POT1	683	30	13528	3.301122498779893	1.0	0.510323917452871	68.300071019498
SP_PIR_KEYWORDS	transport protein	3	0.37267080745341613	0.06243458257308688	ABCF2, RBP1, ABCC1	802	10	19235	7.195137157107232	0.9999999999999964	0.31186748275315845	60.642658989762275
UP_SEQ_FEATURE	repeat:ARM 8	4	0.4968944099378882	0.06245905582266509	PKP4, KPNA4, KPNA2, KPNA1	802	22	19113	4.333031058716844	1.0	0.9659151008515614	67.31048607590124
UP_SEQ_FEATURE	repeat:ARM 3	5	0.6211180124223602	0.06249118886338864	PKP4, RAP1GDS1, KPNA4, KPNA2, KPNA1	802	36	19113	3.309954280964256	1.0	0.9631243449542652	67.3299043325591
SP_PIR_KEYWORDS	Isomerase	10	1.2422360248447204	0.06315688685779636	PPIF, EBP, RPE, PPID, SRR, ECHDC1, TOP3A, PDIA6, FKBP1A, RANBP2	802	120	19235	1.9986492103075644	0.9999999999999976	0.31205025628774785	61.07896096134711
GOTERM_BP_FAT	GO:0007167~enzyme linked receptor protein signaling pathway	25	3.1055900621118013	0.06372829389609756	MPZL1, IL6ST, RHOQ, FKBP1A, ABI1, FSTL1, MSX2, MAP3K7, PTK2, UBE2D3, FNTA, CEP57, SYK, BMP4, SOCS2, CREB1, MET, STAT3, NCK1, ARF4, SPTBN1, BMP7, BAMBI, BMPR1A, TOB1	683	342	13528	1.4478607450789003	1.0	0.518539034545836	69.29115526953274
GOTERM_BP_FAT	GO:0006112~energy reserve metabolic process	6	0.7453416149068323	0.06374297088178121	PPP1R2, PYGL, IL6ST, PRKAG2, PHKA1, GYG1	683	43	13528	2.7637304640947935	1.0	0.5172724964030153	69.29978501300775
GOTERM_BP_FAT	GO:0007093~mitotic cell cycle checkpoint	6	0.7453416149068323	0.06374297088178121	TRRAP, ZWILCH, TPR, BUB3, RAD17, DLG1	683	43	13528	2.7637304640947935	1.0	0.5172724964030153	69.29978501300775
GOTERM_MF_FAT	GO:0003713~transcription coactivator activity	17	2.111801242236025	0.06390774445483027	ENY2, SUB1, RAN, CREM, TRRAP, MED21, MED6, MED7, MAX, TAF12, YAF2, PSMC3, MED17, NPM1, TAF9, RNF14, TFDP1	641	214	12983	1.6089856678379284	1.0	0.6242764559897205	64.37761374818875
GOTERM_MF_FAT	GO:0042393~histone binding	6	0.7453416149068323	0.06396061194283792	TBL1XR1, RBBP4, SET, NPM1, DEK, SMARCA4	641	44	12983	2.761948659764572	1.0	0.6187070901536922	64.40904491623103
GOTERM_MF_FAT	GO:0042826~histone deacetylase binding	5	0.6211180124223602	0.06415331840210478	RBBP4, NUDT21, HDAC9, KPNA2, YWHAE	641	31	12983	3.2668209954204617	1.0	0.6140619865968169	64.52339455266345
GOTERM_MF_FAT	GO:0030983~mismatched DNA binding	4	0.4968944099378882	0.0641755447338481	MSH6, MSH3, MSH2, PCNA	641	19	12983	4.26406108875934	1.0	0.6084988945034606	64.5365612421207
INTERPRO	IPR001623:Heat shock protein DnaJ, N-terminal	6	0.7453416149068323	0.06420148207743018	DNAJC10, DNAJA1, DNAJB1, SEC63, DNAJB6, DNAJA2	753	48	16659	2.765438247011952	1.0	0.9130641209707071	66.36627396519927
SP_PIR_KEYWORDS	glycosyltransferase	15	1.8633540372670807	0.0642142538036701	NAMPT, ALG6, GYG1, HPRT1, MGAT2, PYGL, PARP8, MTAP, PIGC, HAS2, B3GNT2, OGT, PARP2, ALG13, B4GALT4	802	214	19235	1.6811068124082318	0.9999999999999987	0.31362598755957904	61.70954107317868
GOTERM_BP_FAT	GO:0003001~generation of a signal involved in cell-cell signaling	9	1.1180124223602486	0.0642636989484334	SYT1, CYB5R4, YWHAZ, PSEN1, LYN, RAB14, LIN7C, GAL, SYK	683	85	13528	2.0971837051072257	1.0	0.5188861584584199	69.60448401154231
GOTERM_CC_FAT	GO:0031965~nuclear membrane	8	0.9937888198757764	0.06440719229224691	SUMO1, PSEN1, MRPL19, PCNA, CBX3, PAFAH1B1, WTAP, MATR3	624	73	12782	2.2448191078328064	0.9999999999999987	0.3346054972879938	61.80358827641115
UP_SEQ_FEATURE	lipid moiety-binding region:S-geranylgeranyl cysteine	9	1.1180124223602486	0.0644830003745176	RAP2B, RAP2C, RAB9A, RAB4A, RAB22A, RALB, RAB5A, RAB14, RAB1A	802	102	19113	2.102794484377292	1.0	0.9641960769564756	68.51257756491789
SP_PIR_KEYWORDS	repressor	26	3.229813664596273	0.06455179907661354	EID1, CNBP, CNOT8, CREM, TH1L, CBX3, TCF7L2, YBX1, BATF, MAX, ZNF148, SAFB, ANP32A, EWSR1, ENO1, NFX1, NKRF, TBL1XR1, RBBP4, HNRPDL, HHEX, TRIM33, DR1, NAB1, NGDN, HDAC9	802	435	19235	1.4335139163585289	0.9999999999999989	0.3122057122328161	61.90883118649793
GOTERM_BP_FAT	GO:0045937~positive regulation of phosphate metabolic process	10	1.2422360248447204	0.06500537014237026	BMP4, CAV1, PSEN1, LYN, IL6ST, PRKAG2, CD24, BMP7, BMPR1A, SYK	683	100	13528	1.9806734992679358	1.0	0.5217255012014961	70.0335393478702
GOTERM_BP_FAT	GO:0010562~positive regulation of phosphorus metabolic process	10	1.2422360248447204	0.06500537014237026	BMP4, CAV1, PSEN1, LYN, IL6ST, PRKAG2, CD24, BMP7, BMPR1A, SYK	683	100	13528	1.9806734992679358	1.0	0.5217255012014961	70.0335393478702
UP_SEQ_FEATURE	site:Cleavage	7	0.8695652173913043	0.06501697948393832	BID, TMPRSS2, PSEN1, SUB1, MET, POLA1, EMR2	802	68	19113	2.4532602317735073	1.0	0.9624430000917436	68.82271046168711
UP_SEQ_FEATURE	zinc finger region:C4-type	7	0.8695652173913043	0.06501697948393832	RPA1, POLR3K, POLR2K, UBC, POLA1, TOP3A, ASAP1	802	68	19113	2.4532602317735073	1.0	0.9624430000917436	68.82271046168711
SP_PIR_KEYWORDS	heterodimer	9	1.1180124223602486	0.0655398831395966	INHBB, FNTA, MAT2A, CREM, ITGB4, SPTBN1, PPP3CA, CAPN2, PLAU	802	103	19235	2.0956710166331747	0.9999999999999993	0.31346962426090563	62.48666996904143
BBID	61.Myc_network	4	0.4968944099378882	0.06580559656691176	MAX, EIF4E, YAF2, MYC	28	13	358	3.9340659340659334	0.9667445323416277	0.6784209954545238	48.08786202795855
GOTERM_BP_FAT	GO:0010552~positive regulation of specific transcription from RNA polymerase II promoter	7	0.8695652173913043	0.0662202680685214	HHEX, CREB1, PRKDC, RHOQ, TAF9, TCF7L2, SMARCA4	683	57	13528	2.4324060517325528	1.0	0.5271562393696807	70.72402284173458
GOTERM_CC_FAT	GO:0031968~organelle outer membrane	10	1.2422360248447204	0.0669249086374527	BID, DNM1L, ACSL1, PSEN1, MCL1, SH3GLB1, TOMM22, BCL2L1, AKAP1, VDAC3	624	104	12782	1.9696129191321494	0.9999999999999997	0.342215120102358	63.26291922127887
SMART	SM00177:ARF	4	0.4968944099378882	0.06698120734176163	ARF3, ARFRP1, ARF4, ARF6	393	22	9079	4.200323849178811	0.9999999445904909	0.6480556326954559	59.15825599658366
SMART	SM00358:DSRM	4	0.4968944099378882	0.06698120734176163	NKRF, PRKRA, ILF3, STAU1	393	22	9079	4.200323849178811	0.9999999445904909	0.6480556326954559	59.15825599658366
BIOCARTA	h_skp2e2fPathway:E2F1 Destruction Pathway	4	0.4968944099378882	0.067509647974111	SKP1, CDK2, CUL1, TFDP1	143	10	1437	4.01958041958042	0.9999990896150458	0.9990458590490735	58.32883713101688
GOTERM_BP_FAT	GO:0006383~transcription from RNA polymerase III promoter	4	0.4968944099378882	0.0677462354334242	POLR3K, POLR2K, GTF3C4, GTF3C3	683	19	13528	4.169838945827233	1.0	0.5341891473509253	71.57002690380901
GOTERM_CC_FAT	GO:0044445~cytosolic part	13	1.6149068322981366	0.06781810794049722	TCP1, IDE, RGS19, CCT2, MRPS7, PRDX3, TCF7L2, CCT5, RPL3, C19ORF2, UBC, PIK3CA, ENO1	624	152	12782	1.7519188596491226	0.9999999999999998	0.34277623179739225	63.768044614311655
UP_SEQ_FEATURE	repeat:ARM 2	5	0.6211180124223602	0.06784541166518235	PKP4, RAP1GDS1, KPNA4, KPNA2, KPNA1	802	37	19113	3.2204960571544112	1.0	0.9650411009107791	70.41801749780147
GOTERM_CC_FAT	GO:0016281~eukaryotic translation initiation factor 4F complex	3	0.37267080745341613	0.06801110662130877	EIF4B, EIF4E, ANKHD1	624	9	12782	6.827991452991454	0.9999999999999998	0.34040519435681005	63.876337112855666
GOTERM_BP_FAT	GO:0051187~cofactor catabolic process	5	0.6211180124223602	0.06854537883113976	BLVRA, NNT, SDHC, IDH3A, FH	683	31	13528	3.194634676238606	1.0	0.5371758026663875	72.00381315657354
UP_SEQ_FEATURE	active site:Glycyl thioester intermediate	7	0.8695652173913043	0.06881315166684693	UBE2N, UBE2D3, UBE2A, UBR5, HERC4, UBA6, UBE2H	802	69	19113	2.4177057356608476	1.0	0.9641775941361	70.94595301619965
INTERPRO	IPR018253:Heat shock protein DnaJ, conserved site	6	0.7453416149068323	0.06896934649745179	DNAJC10, DNAJA1, DNAJB1, SEC63, DNAJB6, DNAJA2	753	49	16659	2.7090007317668103	1.0	0.9228024165196658	69.07239600489602
GOTERM_BP_FAT	GO:0030509~BMP signaling pathway	6	0.7453416149068323	0.06907492780028704	MSX2, BMP4, UBE2D3, FSTL1, BMP7, BMPR1A	683	44	13528	2.7009184080926394	1.0	0.5386828133920343	72.28780883042951
GOTERM_MF_FAT	GO:0050998~nitric-oxide synthase binding	3	0.37267080745341613	0.06938936452970272	ACTB, CAV2, CAV1	641	9	12983	6.751430057202289	1.0	0.6326177061306739	67.50192748975135
GOTERM_MF_FAT	GO:0016668~oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	3	0.37267080745341613	0.06938936452970272	GSR, DLD, PRDX3	641	9	12983	6.751430057202289	1.0	0.6326177061306739	67.50192748975135
GOTERM_BP_FAT	GO:0042325~regulation of phosphorylation	32	3.9751552795031055	0.06955554786544774	CAV1, IL6ST, PTPLAD1, PRKAG2, FKBP1A, PRDX3, PDCD4, APLP2, CCNE2, MAP3K7, MCM7, NPM1, PRKAA1, CD24, AGK, SYK, BMP4, CDC6, GTPBP4, LYN, NF1, MET, GTF2H1, CDKN1C, SPAG9, MAP4K5, PSEN1, PRKAR1A, LRP8, BMP7, RAD17, BMPR1A	683	466	13528	1.360119141128196	1.0	0.5399148544781299	72.54320727795877
UP_SEQ_FEATURE	domain:Guanylate kinase-like	4	0.4968944099378882	0.06967472157012751	TJP1, CASK, DLG3, DLG1	802	23	19113	4.144638403990025	1.0	0.9631409096961341	71.4084863112295
GOTERM_BP_FAT	GO:0008284~positive regulation of cell proliferation	29	3.602484472049689	0.06970809111563943	NAMPT, CNBP, IL6ST, EIF5A, BCL2L1, PRDX3, SSR1, RPA1, FNTB, FNTA, NPM1, CD24, IL13RA1, MYC, FOSL1, SYK, DNAJA2, BMP4, UBE2A, ADAM10, LYN, STAT1, PROX1, CDK2, MAPK1, NCK1, RIPK2, MCTS1, BMPR1A	683	414	13528	1.3874282965886504	1.0	0.5393960601153448	72.6238020432482
GOTERM_BP_FAT	GO:0006164~purine nucleotide biosynthetic process	13	1.6149068322981366	0.07065701510406912	MSH2, PRKAG2, HPRT1, ATP6V1D, GART, ATP6V1C1, MTHFD1, ATP6V1A, ATP5S, ADK, PAICS, ATP6V0A2, PRPS1	683	148	13528	1.7397807763839974	1.0	0.5430832620454725	73.12016205006661
GOTERM_BP_FAT	GO:0030518~steroid hormone receptor signaling pathway	7	0.8695652173913043	0.07087268723220848	YWHAH, RAN, MED17, UBR5, DNAJA1, RBM9, RNF14	683	58	13528	2.390468016357853	1.0	0.5428919848328795	73.23178379587073
GOTERM_CC_FAT	GO:0005839~proteasome core complex	4	0.4968944099378882	0.07089768633663938	PSMA2, PSMA1, PSMA5, PSMA3	624	20	12782	4.096794871794871	1.0	0.349178263083999	65.46048040593705
SP_PIR_KEYWORDS	multifunctional enzyme	7	0.8695652173913043	0.07100591159167784	MTHFD1, GPHN, ALDH18A1, MGEA5, GAPDH, PAICS, GART	802	70	19235	2.398379052369077	1.0	0.33256109979353676	65.53855471282877
GOTERM_MF_FAT	GO:0031072~heat shock protein binding	8	0.9937888198757764	0.07164619531242042	NPAS2, PPID, DNAJC10, DNAJA1, DNAJB1, SEC63, DNAJB6, DNAJA2	641	74	12983	2.1896529915250666	1.0	0.6393008077190299	68.71210219576619
GOTERM_CC_FAT	GO:0005741~mitochondrial outer membrane	9	1.1180124223602486	0.07180193003474386	BID, DNM1L, ACSL1, MCL1, SH3GLB1, TOMM22, BCL2L1, AKAP1, VDAC3	624	90	12782	2.048397435897436	1.0	0.34969704448602623	65.94326610495803
INTERPRO	IPR002194:Chaperonin TCP-1, conserved site	3	0.37267080745341613	0.07200559769968513	CCT5, TCP1, CCT2	753	10	16659	6.637051792828685	1.0	0.9264497776289701	70.68765621097401
GOTERM_BP_FAT	GO:0050853~B cell receptor signaling pathway	3	0.37267080745341613	0.07219902633032364	MAPK1, LYN, SYK	683	9	13528	6.602244997559785	1.0	0.5484705203500018	73.90867092898345
GOTERM_BP_FAT	GO:0009086~methionine biosynthetic process	3	0.37267080745341613	0.07219902633032364	MTHFD1, ENOPH1, MTRR	683	9	13528	6.602244997559785	1.0	0.5484705203500018	73.90867092898345
GOTERM_BP_FAT	GO:0046641~positive regulation of alpha-beta T cell proliferation	3	0.37267080745341613	0.07219902633032364	RIPK2, CD24, SYK	683	9	13528	6.602244997559785	1.0	0.5484705203500018	73.90867092898345
GOTERM_MF_FAT	GO:0016796~exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4	0.4968944099378882	0.07283958353865906	RAD1, EXOSC9, EXOSC2, FEN1	641	20	12983	4.050858034321373	1.0	0.64016128349779	69.33485036765587
GOTERM_MF_FAT	GO:0004298~threonine-type endopeptidase activity	4	0.4968944099378882	0.07283958353865906	PSMA2, PSMA1, PSMA5, PSMA3	641	20	12983	4.050858034321373	1.0	0.64016128349779	69.33485036765587
GOTERM_MF_FAT	GO:0070003~threonine-type peptidase activity	4	0.4968944099378882	0.07283958353865906	PSMA2, PSMA1, PSMA5, PSMA3	641	20	12983	4.050858034321373	1.0	0.64016128349779	69.33485036765587
UP_SEQ_FEATURE	compositionally biased region:Arg/Lys-rich (basic)	5	0.6211180124223602	0.07342862683513947	PRPF4B, METAP2, SNRPD1, SEMA3A, TTC3	802	38	19113	3.1357461609135058	1.0	0.9670519431777229	73.3439856268733
UP_SEQ_FEATURE	domain:Helicase C-terminal	9	1.1180124223602486	0.07372872014898735	ATRX, DDX18, CHD1L, DDX3X, DDX19B, DHX15, SKIV2L2, DDX5, SMARCA4	802	105	19113	2.042714641966512	1.0	0.9651733878334854	73.49326021664422
SMART	SM00185:ARM	5	0.6211180124223602	0.07377788408085623	PKP4, RAP1GDS1, KPNA4, KPNA2, KPNA1	393	37	9079	3.121862320335603	0.9999999904862804	0.6626053002999321	62.83853577150907
SP_PIR_KEYWORDS	golgi apparatus	33	4.099378881987578	0.07399246307602086	CAV2, CAV1, RAB9A, CNIH, ARFRP1, PITPNB, ARF6, LMAN1, UXS1, RAB1A, PICALM, TMED2, SH3GLB1, GORASP2, SLC30A5, B3GNT2, B4GALT4, MOBKL3, AP3B1, SCAMP1, SEC23A, LYN, ROCK1, AP4S1, MGAT2, PSEN1, SCYL2, VAMP7, ARF3, ARF4, YIPF5, GOSR2, TMCO1	802	588	19235	1.3460290600030536	1.0	0.34133568071943776	67.10678248170396
SP_PIR_KEYWORDS	endonexin fold	3	0.37267080745341613	0.0742562413543605	ANXA7, ANXA3, ANXA2	802	11	19235	6.541033779188393	1.0	0.3394768993928243	67.24204955708511
INTERPRO	IPR001159:Double-stranded RNA binding	4	0.4968944099378882	0.07458385167057827	NKRF, PRKRA, ILF3, STAU1	753	22	16659	4.022455632017384	1.0	0.9285869872231263	71.99672060312021
INTERPRO	IPR006688:ADP-ribosylation factor	4	0.4968944099378882	0.07458385167057827	ARF3, ARFRP1, ARF4, ARF6	753	22	16659	4.022455632017384	1.0	0.9285869872231263	71.99672060312021
GOTERM_MF_FAT	GO:0016763~transferase activity, transferring pentosyl groups	6	0.7453416149068323	0.07462383814221572	NAMPT, MSH2, PARP8, MTAP, HPRT1, PARP2	641	46	12983	2.6418639354269824	1.0	0.6440418758768605	70.24432565488877
UP_SEQ_FEATURE	short sequence motif:BH1	3	0.37267080745341613	0.0750879120589223	MCL1, BCL2L1, BCL2L13	802	11	19113	6.499546588075266	1.0	0.9650316158844487	74.1595499313114
UP_SEQ_FEATURE	cross-link:Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)	3	0.37267080745341613	0.0750879120589223	SUMO3, SUMO2, SUMO1, UBC	802	11	19113	6.499546588075266	1.0	0.9650316158844487	74.1595499313114
GOTERM_BP_FAT	GO:0032583~regulation of gene-specific transcription	12	1.4906832298136645	0.0757417517481137	CDKN1C, HHEX, TBL1XR1, CREB1, TAF9B, PRKDC, RHOQ, TAF9, HDAC9, PROX1, TCF7L2, SMARCA4	683	134	13528	1.7737374620309874	1.0	0.5651027273070925	75.63831639917763
SP_PIR_KEYWORDS	serine/threonine-protein kinase	23	2.857142857142857	0.07636836439255967	CSNK1A1, SRPK2, PRPF4B, ROCK1, BRAF, NUAK1, MAPKAPK5, MAP2K4, PRKDC, CASK, ATR, CDK2, MAP3K7, MAPK1, RPS6KA3, MAP4K5, RIOK3, MAPK9, RIPK2, PRKAA1, TLK2, STK38L, BMPR1A	802	381	19235	1.447840372821228	1.0	0.34465824250521415	68.3066349308534
GOTERM_BP_FAT	GO:0009065~glutamine family amino acid catabolic process	4	0.4968944099378882	0.07683117343339443	GLUD2, GLUD1, GLS, GAD1	683	20	13528	3.961346998535871	1.0	0.5691645077789277	76.14804563628911
UP_SEQ_FEATURE	repeat:ARM 7	4	0.4968944099378882	0.0772472377991355	PKP4, KPNA4, KPNA2, KPNA1	802	24	19113	3.9719451371571073	1.0	0.9661563450595567	75.18571577806026
GOTERM_MF_FAT	GO:0016776~phosphotransferase activity, phosphate group as acceptor	5	0.6211180124223602	0.07733714275607616	CASK, DLG3, AK2, TAF9, DLG1	641	33	12983	3.0688318441828586	1.0	0.6524117977875667	71.57909607864626
INTERPRO	IPR017936:Thioredoxin-like	5	0.6211180124223602	0.0775718430420098	GLRX3, AIFM1, DNAJC10, PDIA6, PRDX3	753	36	16659	3.0727091633466137	1.0	0.9315967937709246	73.44509673934176
GOTERM_BP_FAT	GO:0046649~lymphocyte activation	16	1.9875776397515528	0.07823164378239511	MSH6, MSH2, SWAP70, PRKDC, FKBP1A, TPD52, SKAP2, HPRT1, PSEN1, FYN, NCK1, RIPK2, CD24, HSPD1, HDAC9, SYK	683	199	13528	1.592501305944069	1.0	0.5746741103071595	76.78852659363386
GOTERM_MF_FAT	GO:0030145~manganese ion binding	13	1.6149068322981366	0.07823474429222893	NUDT4, ATR, IDH3A, XPNPEP1, GART, SOD2, PRUNE, FYN, B3GNT2, PDE8A, B4GALT4, FEN1, BMPR1A	641	154	12983	1.709777741759021	1.0	0.6516165108006732	72.00817532902686
KEGG_PATHWAY	hsa05221:Acute myeloid leukemia	8	0.9937888198757764	0.07848388909033653	MAPK1, BRAF, SOS2, PIK3CA, RUNX1, MYC, TCF7L2, STAT3	330	58	5085	2.1253918495297803	0.9999975370061855	0.4932265441563295	62.64933989247419
UP_SEQ_FEATURE	compositionally biased region:Poly-Asp	8	0.9937888198757764	0.07961870131086785	ATRX, PJA1, TAF9B, C1ORF107, C19ORF2, TAF9, TPR, BCAR3	802	89	19113	2.142172658242035	1.0	0.9675217683469722	76.2684002962227
UP_SEQ_FEATURE	cross-link:Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)	8	0.9937888198757764	0.07961870131086785	SUMO3, SUMO2, PAPOLA, HNRNPF, NPM1, HNRNPC, RANBP2, STAT1, TCF7L2	802	89	19113	2.142172658242035	1.0	0.9675217683469722	76.2684002962227
GOTERM_MF_FAT	GO:0009055~electron carrier activity	17	2.111801242236025	0.07997961512376689	GLRX3, ACOX1, ABCE1, CYB5R4, ME2, AIFM1, MTRR, GSR, NNT, SDHC, DLD, NDUFV2, ASPH, STEAP1, GLRX, ETFA, DEGS1	641	221	12983	1.5580223208928359	1.0	0.6549240631881558	72.82497892053846
GOTERM_BP_FAT	GO:0018108~peptidyl-tyrosine phosphorylation	6	0.7453416149068323	0.08045276232544635	LYN, FYN, ABI2, ABI1, STAT1, SYK	683	46	13528	2.583487172958177	1.0	0.5839828826987559	77.77112205863484
GOTERM_CC_FAT	GO:0019867~outer membrane	10	1.2422360248447204	0.0806450308691847	BID, DNM1L, ACSL1, PSEN1, MCL1, SH3GLB1, TOMM22, BCL2L1, AKAP1, VDAC3	624	108	12782	1.8966642924976256	1.0	0.3813448159688013	70.3447353144244
GOTERM_CC_FAT	GO:0000775~chromosome, centromeric region	11	1.3664596273291925	0.08077156940428706	SUMO3, SUMO2, ORC2L, NUP98, PSEN1, CBX3, CLIP1, PAFAH1B1, CBX1, ZWILCH, TPR, BUB3	624	124	12782	1.817126757650951	1.0	0.37855489336351367	70.40368711006698
SP_PIR_KEYWORDS	lipoamide	2	0.2484472049689441	0.0815536260526066	GCSH, DLAT	802	2	19235	23.983790523690775	1.0	0.3610498632721979	70.7851615625614
SP_PIR_KEYWORDS	gout	2	0.2484472049689441	0.0815536260526066	HPRT1, PRPS1	802	2	19235	23.983790523690775	1.0	0.3610498632721979	70.7851615625614
GOTERM_CC_FAT	GO:0000922~spindle pole	5	0.6211180124223602	0.08171095152920406	TUBGCP4, NUMA1, NPM1, SMC3, CALM1	624	34	12782	3.0123491704374055	1.0	0.3788913965668077	70.8379278736335
GOTERM_BP_FAT	GO:0000165~MAPKKK cascade	15	1.8633540372670807	0.08175378141581952	CAV1, BRAF, PTPLAD1, MET, MAP2K4, NF1, MAP3K7, SPAG9, MAPK1, MAP4K5, PSEN1, MAPK9, PRKAA1, RAPGEF2, SYK	683	184	13528	1.6146794830988607	1.0	0.5887747310670831	78.32829633323793
UP_SEQ_FEATURE	region of interest:2 X 16 AA Gly-rich approximate repeats	2	0.2484472049689441	0.082063063198543	HNRNPH2, HNRNPH1	802	2	19113	23.83167082294264	1.0	0.9688923082779097	77.33767918793232
UP_SEQ_FEATURE	region of interest:Interaction with DNA	2	0.2484472049689441	0.082063063198543	TDP1, RUNX1	802	2	19113	23.83167082294264	1.0	0.9688923082779097	77.33767918793232
UP_SEQ_FEATURE	region of interest:First lumenal domain	2	0.2484472049689441	0.082063063198543	LAMP1, LAMP2	802	2	19113	23.83167082294264	1.0	0.9688923082779097	77.33767918793232
UP_SEQ_FEATURE	region of interest:Second lumenal domain	2	0.2484472049689441	0.082063063198543	LAMP1, LAMP2	802	2	19113	23.83167082294264	1.0	0.9688923082779097	77.33767918793232
UP_SEQ_FEATURE	glycosylation site:N-linked (GlcNAc...) (polylactosaminoglycan)	2	0.2484472049689441	0.082063063198543	LAMP1, LAMP2	802	2	19113	23.83167082294264	1.0	0.9688923082779097	77.33767918793232
UP_SEQ_FEATURE	region of interest:2 X 19 AA perfect repeats	2	0.2484472049689441	0.082063063198543	HNRNPH2, HNRNPH1	802	2	19113	23.83167082294264	1.0	0.9688923082779097	77.33767918793232
OMIM_DISEASE	Nonsmall cell lung cancer, somatic	2	0.2484472049689441	0.08215195764545605	BRAF, PIK3CA	155	2	3671	23.683870967741935	0.999999999979336	0.999999999979336	67.9471139427916
OMIM_DISEASE	Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33	2	0.2484472049689441	0.08215195764545605	ECHDC1, RNF146	155	2	3671	23.683870967741935	0.999999999979336	0.999999999979336	67.9471139427916
GOTERM_CC_FAT	GO:0008180~signalosome	3	0.37267080745341613	0.08234105789970901	COPS2, COPS3, COPS8	624	10	12782	6.145192307692308	1.0	0.37806648009808386	71.12587100395582
GOTERM_BP_FAT	GO:0001709~cell fate determination	5	0.6211180124223602	0.08249449506943568	BMP4, MCL1, PROX1, IFRD1, SMARCA4	683	33	13528	3.001020453436266	1.0	0.5908998262259043	78.63959591237858
GOTERM_BP_FAT	GO:0021987~cerebral cortex development	5	0.6211180124223602	0.08249449506943568	PSEN1, NF1, LRP8, PAFAH1B1, YWHAE	683	33	13528	3.001020453436266	1.0	0.5908998262259043	78.63959591237858
SMART	SM00547:ZnF_RBZ	4	0.4968944099378882	0.0827079419336523	FUS, YAF2, RANBP2, EWSR1	393	24	9079	3.8502968617472435	0.9999999990788303	0.6852114918877061	67.20945960331812
INTERPRO	IPR008144:Guanylate kinase	4	0.4968944099378882	0.08301293543795761	TJP1, CASK, DLG3, DLG1	753	23	16659	3.847566256712281	1.0	0.9398143928134297	75.90357414670623
GOTERM_BP_FAT	GO:0030522~intracellular receptor-mediated signaling pathway	8	0.9937888198757764	0.08322624366504805	YWHAH, RAN, MED17, CREM, UBR5, DNAJA1, RBM9, RNF14	683	75	13528	2.112718399219131	1.0	0.5929603956161915	78.94297834485718
GOTERM_BP_FAT	GO:0006366~transcription from RNA polymerase II promoter	18	2.236024844720497	0.08324038307121462	COPS2, POLR2K, NFYA, STAT1, GTF2B, YBX1, GTF2H1, FUBP1, MSL3, MED7, MAX, TAF12, MED17, PIR, TAF9, FOSL1, MYC, NFX1	683	234	13528	1.5235949994368736	1.0	0.59171654313352	78.94880026585133
GOTERM_BP_FAT	GO:0007243~protein kinase cascade	26	3.229813664596273	0.08354007886350628	CAV1, IL6ST, PTPLAD1, PRKAG2, MAP3K7, PIK3CA, PRKAA1, RAPGEF2, STK38L, SYK, SRPK2, BRAF, SOCS2, MET, MAP2K4, NF1, STAT1, STAT3, TANK, SPAG9, MAPK1, RPS6KA3, MAP4K5, PSEN1, FYN, MAPK9	683	370	13528	1.3918246211071978	1.0	0.5917860127034167	79.07184350753751
GOTERM_BP_FAT	GO:0006928~cell motion	32	3.9751552795031055	0.08377690963588605	CAV2, PRKDC, ABI2, ARF6, ARPC5, TPM4, DSTN, ACTR3, PTK2, TUBB, ARPC2, DNAJA1, PAFAH1B1, SEMA3A, CD24, B3GNT2, SYK, ACTB, ROCK1, MSH2, MET, YWHAE, STAT3, PSEN1, FYN, NCK1, LYST, UBC, LRP8, BMP7, APBB2, PLAU	683	475	13528	1.3343484626647144	1.0	0.5915687187751277	79.16859618265993
INTERPRO	IPR000225:Armadillo	5	0.6211180124223602	0.08402023986824268	PKP4, RAP1GDS1, KPNA4, KPNA2, KPNA1	753	37	16659	2.989662969742651	1.0	0.9379477795457424	76.3345814831452
SP_PIR_KEYWORDS	cell division	17	2.111801242236025	0.08472270552712935	CSNK1A1, CDC6, PDS5A, RAN, ANAPC10, CDC16, CCNG2, SMC3, CDK2, CCNE2, DCLRE1A, CHMP1B, PAFAH1B1, MAPRE1, ZWILCH, BUB3, STAG2	802	264	19235	1.5444107534194818	1.0	0.3696119759588954	72.20983742892987
UP_SEQ_FEATURE	repeat:2-1	4	0.4968944099378882	0.08516282332238878	HNRNPH2, SYNCRIP, HNRNPH1, CANX	802	25	19113	3.813067331670823	1.0	0.9710037081280195	78.62843448057481
GOTERM_BP_FAT	GO:0016481~negative regulation of transcription	31	3.8509316770186333	0.0852978871367155	COPS2, EID1, TH1L, TAF9B, CBX3, RBM9, TCEAL1, PDCD4, SUMO1, ORC2L, ZNF148, LANCL2, ENO1, NFX1, NKRF, TBL1XR1, STRN3, ILF3, SNW1, PROX1, STAT3, CDKN1C, HHEX, TRIM33, YAF2, DR1, NAB1, YWHAQ, HDAC9, DNAJB6, SMARCA4	683	459	13528	1.3377097707474077	1.0	0.5971578996909038	79.779968241069
GOTERM_BP_FAT	GO:0051098~regulation of binding	13	1.6149068322981366	0.08568413412781253	GTPBP4, FKBP1A, PRDX3, ATR, PROX1, UBE2N, SUMO1, PSEN1, AIDA, NPM1, RIPK2, SMARCA4, CALM1	683	153	13528	1.682925195456416	1.0	0.597596963122144	79.93250437731217
BIOCARTA	h_ranbp2Pathway:Sumoylation by RanBP2 Regulates Transcriptional Repression	4	0.4968944099378882	0.08631304314919457	SUMO1, RAN, RANBP2, HDAC9	143	11	1437	3.6541640178003814	0.9999999841988888	0.9974906424711416	67.7121124366034
BIOCARTA	h_actinYPathway:Y branching of actin filaments	4	0.4968944099378882	0.08631304314919457	NCK1, PIR, ABI2, NCKAP1	143	11	1437	3.6541640178003814	0.9999999841988888	0.9974906424711416	67.7121124366034
GOTERM_BP_FAT	GO:0001836~release of cytochrome c from mitochondria	4	0.4968944099378882	0.08641813996993873	BID, BCL2L1, MYC, SOD2	683	21	13528	3.7727114271770206	1.0	0.5995793536885299	80.21938744312628
SP_PIR_KEYWORDS	purine biosynthesis	3	0.37267080745341613	0.08671959285601497	MTHFD1, PAICS, GART	802	12	19235	5.995947630922693	1.0	0.37379379588739803	73.07404507322576
SMART	SM00490:HELICc	9	1.1180124223602486	0.08721271872537323	ATRX, DDX18, CHD1L, DDX3X, DDX19B, DHX15, SKIV2L2, DDX5, SMARCA4	393	106	9079	1.961471986173124	0.9999999997187654	0.6857180712835137	69.22957636071816
GOTERM_BP_FAT	GO:0018196~peptidyl-asparagine modification	3	0.37267080745341613	0.08731651250794076	MGAT2, MAGT1, TUSC3	683	10	13528	5.9420204978038065	1.0	0.6022642056909302	80.56524298389056
GOTERM_BP_FAT	GO:0018279~protein amino acid N-linked glycosylation via asparagine	3	0.37267080745341613	0.08731651250794076	MGAT2, MAGT1, TUSC3	683	10	13528	5.9420204978038065	1.0	0.6022642056909302	80.56524298389056
GOTERM_BP_FAT	GO:0006303~double-strand break repair via nonhomologous end joining	3	0.37267080745341613	0.08731651250794076	XRCC5, POLA1, PRKDC	683	10	13528	5.9420204978038065	1.0	0.6022642056909302	80.56524298389056
UP_SEQ_FEATURE	domain:DRBM 1	3	0.37267080745341613	0.08767598436545283	PRKRA, ILF3, STAU1	802	12	19113	5.957917705735661	1.0	0.9722258040139148	79.62374144788187
UP_SEQ_FEATURE	compositionally biased region:Gly/Ser-rich	3	0.37267080745341613	0.08767598436545283	DDX3X, MAP2K4, AMMECR1	802	12	19113	5.957917705735661	1.0	0.9722258040139148	79.62374144788187
UP_SEQ_FEATURE	domain:DRBM 2	3	0.37267080745341613	0.08767598436545283	PRKRA, ILF3, STAU1	802	12	19113	5.957917705735661	1.0	0.9722258040139148	79.62374144788187
GOTERM_BP_FAT	GO:0050870~positive regulation of T cell activation	8	0.9937888198757764	0.08790889205565564	MAP3K7, IL6ST, NCK1, RIPK2, HSPD1, CD24, SYK, AP3B1	683	76	13528	2.0849194729136165	1.0	0.603581071423916	80.79016487732002
INTERPRO	IPR017861:Peptidase M22, glycoprotease, subgroup	2	0.2484472049689441	0.08824642838780344	OSGEP, OSGEPL1	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR016151:DNA mismatch repair protein MutS, N-terminal	2	0.2484472049689441	0.08824642838780344	MSH6, MSH3	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR006844:OST3/OST6	2	0.2484472049689441	0.08824642838780344	MAGT1, TUSC3	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR006096:Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal	2	0.2484472049689441	0.08824642838780344	GLUD2, GLUD1	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR003162:Transcription factor TAFII-31	2	0.2484472049689441	0.08824642838780344	TAF9B, TAF9	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR006095:Glutamate/phenylalanine/leucine/valine dehydrogenase	2	0.2484472049689441	0.08824642838780344	GLUD2, GLUD1	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR000905:Peptidase M22, glycoprotease	2	0.2484472049689441	0.08824642838780344	OSGEP, OSGEPL1	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR004023:Mago nashi protein	2	0.2484472049689441	0.08824642838780344	MAGOH, MAGOHB	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR003957:Transcription factor, CBFA/NFYB, DNA topoisomerase	2	0.2484472049689441	0.08824642838780344	DR1, NFYB	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
INTERPRO	IPR006097:Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region	2	0.2484472049689441	0.08824642838780344	GLUD2, GLUD1	753	2	16659	22.123505976095615	1.0	0.9427170438670606	78.06521120919454
GOTERM_BP_FAT	GO:0051604~protein maturation	11	1.3664596273291925	0.08825786096732469	CD55, METAP2, PSEN1, ATP6AP2, CD46, SEC11A, FKBP1A, SPCS2, HSPD1, PCSK5, MYC	683	122	13528	1.7858531550776469	1.0	0.6038275455824529	80.9215128310078
GOTERM_BP_FAT	GO:0042254~ribosome biogenesis	11	1.3664596273291925	0.08825786096732469	GTPBP4, EXOSC9, TSR1, NOLC1, NPM1, EXOSC2, WBP11, FTSJ1, UTP14A, DIMT1L, GEMIN4	683	122	13528	1.7858531550776469	1.0	0.6038275455824529	80.9215128310078
GOTERM_BP_FAT	GO:0048584~positive regulation of response to stimulus	18	2.236024844720497	0.08849501802232654	ADAM10, LYN, IL6ST, F2RL1, POLR3C, UBE2N, MAP3K7, MAPK1, CD55, PSEN1, FYN, CD46, LANCL2, RIPK2, TAF9, CD24, HSPD1, SYK	683	236	13528	1.5106831774077476	1.0	0.6035874135619193	81.01029159226977
GOTERM_BP_FAT	GO:0043434~response to peptide hormone stimulus	13	1.6149068322981366	0.08891112849056362	CAV2, SOCS2, LYN, GGH, RHOQ, PRKDC, BCL2L1, GAL, STAT1, STAT3, HDAC9, BMP7, EIF2B3	683	154	13528	1.671997109771634	1.0	0.6041235565919296	81.16511891620856
GOTERM_CC_FAT	GO:0030863~cortical cytoskeleton	6	0.7453416149068323	0.08895498565795594	ACTB, LOC100129652, LANCL2, SPTBN1, MAPRE1, DSTN	624	49	12782	2.508241758241758	1.0	0.39915786759508165	73.99272422532555
UP_SEQ_FEATURE	domain:Protein kinase	27	3.354037267080745	0.08939797030277422	PRPF4B, NUAK1, MAPKAPK5, CASK, MAP3K7, PTK2, PRKAA1, TLK2, STK38L, SYK, CSNK1A1, SRPK2, BRAF, ROCK1, LYN, RYK, MET, MAP2K4, CDK2, MAPK1, MAP4K5, RIOK3, SCYL2, FYN, MAPK9, RIPK2, BMPR1A	802	469	19113	1.371972520723777	1.0	0.9724601331011418	80.28031601586902
GOTERM_BP_FAT	GO:0043648~dicarboxylic acid metabolic process	5	0.6211180124223602	0.08995188896296084	ME2, DLD, GAD1, IDH3A, FH	683	34	13528	2.9127551459822585	1.0	0.6073372884101504	81.54716510257695
GOTERM_CC_FAT	GO:0044437~vacuolar part	7	0.8695652173913043	0.09076478267086538	MTMR2, LAMP2, PSEN1, VAMP7, DLD, VTI1B, ATP6V1D	624	64	12782	2.2404346955128207	1.0	0.4023915122974975	74.72968982937176
GOTERM_BP_FAT	GO:0006275~regulation of DNA replication	7	0.8695652173913043	0.09130650481819047	CDC6, GTPBP4, PCNA, ATR, POT1, RAD17, CDK2	683	62	13528	2.2362442733670242	1.0	0.6118353343599351	82.0334702274183
GOTERM_BP_FAT	GO:0022415~viral reproductive process	7	0.8695652173913043	0.09130650481819047	XRCC5, DERL1, PSIP1, DEK, THOC2, HBXIP, PCSK5	683	62	13528	2.2362442733670242	1.0	0.6118353343599351	82.0334702274183
INTERPRO	IPR001876:Zinc finger, RanBP2-type	4	0.4968944099378882	0.09182914479848682	FUS, YAF2, RANBP2, EWSR1	753	24	16659	3.6872509960159356	1.0	0.9458159456440383	79.43852052057228
SP_PIR_KEYWORDS	SH2 domain	9	1.1180124223602486	0.09193695335043862	SOCS2, LYN, FYN, NCK1, STAT1, CRK, STAT3, BCAR3, SYK	802	111	19235	1.9446316640830357	1.0	0.38903210549588896	75.215381924991
GOTERM_BP_FAT	GO:0000077~DNA damage checkpoint	6	0.7453416149068323	0.09276479914457396	RAD1, MSH2, RINT1, BRIP1, ATR, RAD17	683	48	13528	2.4758418740849195	1.0	0.6166917587830294	82.54345799577256
GOTERM_BP_FAT	GO:0018212~peptidyl-tyrosine modification	6	0.7453416149068323	0.09276479914457396	LYN, FYN, ABI2, ABI1, STAT1, SYK	683	48	13528	2.4758418740849195	1.0	0.6166917587830294	82.54345799577256
UP_SEQ_FEATURE	repeat:ARM 6	4	0.4968944099378882	0.093407022908917	PKP4, KPNA4, KPNA2, KPNA1	802	26	19113	3.66641089583733	1.0	0.975161918392003	81.73252078942164
UP_SEQ_FEATURE	repeat:1-2	4	0.4968944099378882	0.093407022908917	HNRNPH2, SYNCRIP, HNRNPH1, CANX	802	26	19113	3.66641089583733	1.0	0.975161918392003	81.73252078942164
SP_PIR_KEYWORDS	ribosomal protein	13	1.6149068322981366	0.09435787017076902	MRPL42, MRPS28, MRPS15, MRPL9, MRPS7, MRPS30, MRPL13, HNRNPH2, MRPL19, RPL3, UBC, MRPL18, MRPL39	802	188	19235	1.658453600042447	1.0	0.39430899617820403	76.15415741794482
GOTERM_CC_FAT	GO:0032301~MutSalpha complex	2	0.2484472049689441	0.09510883188208241	MSH6, MSH2	624	2	12782	20.483974358974358	1.0	0.4143884671202088	76.4200500973477
GOTERM_CC_FAT	GO:0032302~MutSbeta complex	2	0.2484472049689441	0.09510883188208241	MSH3, MSH2	624	2	12782	20.483974358974358	1.0	0.4143884671202088	76.4200500973477
PIR_SUPERFAMILY	PIRSF002584:molecular chaperone t-complex-type	3	0.37267080745341613	0.09555974736465042	CCT5, TCP1, CCT2	394	10	7396	5.631472081218274	1.0	0.9998948412788734	76.01212800690797
UP_SEQ_FEATURE	region of interest:Substrate binding	10	1.2422360248447204	0.0960279716146213	MTMR2, MTHFD1, MTHFS, RRM1, IDE, ENOPH1, PGK1, GAD1, FH, ENO1	802	130	19113	1.8332054479186648	1.0	0.9762193994238264	82.62677619773164
GOTERM_MF_FAT	GO:0004353~glutamate dehydrogenase [NAD(P)+] activity	2	0.2484472049689441	0.09616405454844151	GLUD2, GLUD1	641	2	12983	20.254290171606865	1.0	0.7199663085157302	79.40794506922691
GOTERM_MF_FAT	GO:0004352~glutamate dehydrogenase activity	2	0.2484472049689441	0.09616405454844151	GLUD2, GLUD1	641	2	12983	20.254290171606865	1.0	0.7199663085157302	79.40794506922691
GOTERM_MF_FAT	GO:0004660~protein farnesyltransferase activity	2	0.2484472049689441	0.09616405454844151	FNTB, FNTA	641	2	12983	20.254290171606865	1.0	0.7199663085157302	79.40794506922691
GOTERM_MF_FAT	GO:0032143~single thymine insertion binding	2	0.2484472049689441	0.09616405454844151	MSH6, MSH2	641	2	12983	20.254290171606865	1.0	0.7199663085157302	79.40794506922691
GOTERM_MF_FAT	GO:0032181~dinucleotide repeat insertion binding	2	0.2484472049689441	0.09616405454844151	MSH3, MSH2	641	2	12983	20.254290171606865	1.0	0.7199663085157302	79.40794506922691
GOTERM_MF_FAT	GO:0070728~leucine binding	2	0.2484472049689441	0.09616405454844151	GLUD2, GLUD1	641	2	12983	20.254290171606865	1.0	0.7199663085157302	79.40794506922691
GOTERM_MF_FAT	GO:0016639~oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	2	0.2484472049689441	0.09616405454844151	GLUD2, GLUD1	641	2	12983	20.254290171606865	1.0	0.7199663085157302	79.40794506922691
GOTERM_CC_FAT	GO:0005758~mitochondrial intermembrane space	5	0.6211180124223602	0.09633292584150985	LYN, AIFM1, AK2, TIMM23, TIMM8A	624	36	12782	2.844996438746439	1.0	0.41535776865551755	76.87700206457077
GOTERM_CC_FAT	GO:0022624~proteasome accessory complex	3	0.37267080745341613	0.097489058560077	PSMD12, PSMD10, PSME3	624	11	12782	5.586538461538462	1.0	0.4160807662437457	77.30100278426832
GOTERM_BP_FAT	GO:0042592~homeostatic process	47	5.838509316770186	0.09768909836187054	XRCC5, GLRX3, CYB5R4, CAV1, DERL1, LDLR, MCL1, IL6ST, F2RL1, DNAJC10, SLC7A8, PRKDC, PDIA6, FKBP1A, BCL2L1, PRDX3, FOXO3, TCF7L2, APLP2, POT1, RPA1, ANXA7, GSR, NPM1, SLC30A5, PPP3CA, CD24, FOXO3B, MYC, GLRX, FH, BMP4, LIPA, LYN, AIFM1, NF1, SELT, STAT3, SOD2, CD55, NPC1, RFC1, PSEN1, PYGL, NAB1, DLD, MGEA5, CLDN1	683	751	13528	1.239569300473941	1.0	0.6354459512713613	84.16640407441703
GOTERM_BP_FAT	GO:0001765~membrane raft formation	2	0.2484472049689441	0.09828988452301021	CAV2, CAV1	683	2	13528	19.806734992679356	1.0	0.6365726515129341	84.35435931373888
GOTERM_BP_FAT	GO:0002441~histamine secretion during acute inflammatory response	2	0.2484472049689441	0.09828988452301021	YWHAZ, LYN	683	2	13528	19.806734992679356	1.0	0.6365726515129341	84.35435931373888
GOTERM_BP_FAT	GO:0002349~histamine production during acute inflammatory response	2	0.2484472049689441	0.09828988452301021	YWHAZ, LYN	683	2	13528	19.806734992679356	1.0	0.6365726515129341	84.35435931373888
GOTERM_BP_FAT	GO:0002553~histamine secretion by mast cell	2	0.2484472049689441	0.09828988452301021	YWHAZ, LYN	683	2	13528	19.806734992679356	1.0	0.6365726515129341	84.35435931373888
GOTERM_BP_FAT	GO:0001821~histamine secretion	2	0.2484472049689441	0.09828988452301021	YWHAZ, LYN	683	2	13528	19.806734992679356	1.0	0.6365726515129341	84.35435931373888
GOTERM_BP_FAT	GO:0002842~positive regulation of T cell mediated immune response to tumor cell	2	0.2484472049689441	0.09828988452301021	HSPD1, CD24	683	2	13528	19.806734992679356	1.0	0.6365726515129341	84.35435931373888
GOTERM_BP_FAT	GO:0018347~protein amino acid farnesylation	2	0.2484472049689441	0.09828988452301021	FNTB, FNTA	683	2	13528	19.806734992679356	1.0	0.6365726515129341	84.35435931373888
GOTERM_BP_FAT	GO:0002840~regulation of T cell mediated immune response to tumor cell	2	0.2484472049689441	0.09828988452301021	HSPD1, CD24	683	2	13528	19.806734992679356	1.0	0.6365726515129341	84.35435931373888
GOTERM_MF_FAT	GO:0003684~damaged DNA binding	6	0.7453416149068323	0.09863663886844863	RAD1, RAD23B, MSH6, MSH3, MSH2, FEN1	641	50	12983	2.430514820592824	1.0	0.724637038095298	80.27100044386492
GOTERM_MF_FAT	GO:0016251~general RNA polymerase II transcription factor activity	6	0.7453416149068323	0.09863663886844863	MED6, MED7, TAF12, MED17, GTF2B, GTF2H1	641	50	12983	2.430514820592824	1.0	0.724637038095298	80.27100044386492
UP_SEQ_FEATURE	nucleotide phosphate-binding region:NAD	7	0.8695652173913043	0.09887525256820706	ME2, NNT, GLUD1, DLD, GAPDH, VDAC3, UXS1	802	76	19113	2.1950223126394537	1.0	0.9774126943449887	83.55143250097883
COG_ONTOLOGY	Translation, ribosomal structure and biogenesis	7	0.8695652173913043	0.09899558751629275	EXOSC9, EIF2S1, HBS1L, EXOSC2, DUS4L, MCTS1, NMD3	92	69	1950	2.1502835538752367	0.8756807569807854	0.4062076621589715	54.76961793720303
GOTERM_CC_FAT	GO:0005637~nuclear inner membrane	4	0.4968944099378882	0.09908012689833257	PSEN1, PCNA, CBX3, MATR3	624	23	12782	3.5624303232998886	1.0	0.4182528816417529	77.87268764801546
BIOCARTA	h_p38mapkPathway:p38 MAPK Signaling Pathway 	7	0.8695652173913043	0.09914502493402622	MAP3K7, MAX, MAPKAPK5, CREB1, MAP2K4, RAPGEF2, STAT1	143	33	1437	2.1315956770502225	0.9999999990530624	0.9944527166993591	72.95341743076777
GOTERM_MF_FAT	GO:0004385~guanylate kinase activity	3	0.37267080745341613	0.09939347571487117	CASK, DLG3, DLG1	641	11	12983	5.523897319529144	1.0	0.7227297409367894	80.52832954895392
GOTERM_MF_FAT	GO:0050750~low-density lipoprotein receptor binding	3	0.37267080745341613	0.09939347571487117	SYT1, DKK1, DNAJA1	641	11	12983	5.523897319529144	1.0	0.7227297409367894	80.52832954895392
GOTERM_MF_FAT	GO:0016566~specific transcriptional repressor activity	5	0.6211180124223602	0.09941994825795446	NKRF, EID1, RFC1, HDAC9, TCF7L2	641	36	12983	2.81309585716762	1.0	0.7181103427643012	80.53727325060832
INTERPRO	IPR002475:BCL2-like apoptosis inhibitor	3	0.37267080745341613	0.099567754384982	MCL1, BCL2L1, BCL2L13	753	12	16659	5.530876494023904	1.0	0.9551920903871156	82.13413620280257
GOTERM_BP_FAT	GO:0060537~muscle tissue development	11	1.3664596273291925	0.09971701155010448	CAV2, GPHN, CAV1, ATG5, SVIL, NDUFV2, NF1, FKBP1A, PPP3CA, MBNL1, PROX1	683	125	13528	1.7429926793557833	1.0	0.6409163112382961	84.7924236790772
SMART	SM00072:GuKc	4	0.4968944099378882	0.09985194510516938	TJP1, CASK, DLG3, DLG1	393	26	9079	3.5541201800743787	0.9999999999902353	0.7184969752012167	74.30084041888195